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9040509 Method of treating human skin and a skin care composition for use in such a method  
One aspect of the invention concerns a cosmetic method of treating human skin by delivering an estrogenic component to said skin. The method comprises applying to the skin a composition...
9034859 Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation  
Methods and compositions for the prevention and treatment of liver damage or disease in a subject in need thereof are provided. The methods involve providing the sulfated oxysterol...
9029414 Triterpenoid compounds and methods of use thereof  
The present invention provides therapeutically active compounds and compositions as receptor antagonists and methods of use thereof. In one aspect, the compounds are useful in modulating pain,...
9029355 Solid ganaxolone compositions and methods for the making and use thereof  
In certain embodiments, the invention is directed to composition comprising stable particles comprising ganaxolone, wherein the volume weighted median diameter (D50) of the particles is from about...
9011309 Devices for thermally induced transformations controlled by irradiation of functionalized fullerenes  
An electromagnetic radiation activated device comprises a property changing material and at least one functionalized fullerene that upon irradiation of the functionalized fullerenes with...
8999963 Transdermal compositions and methods for treatment of fibromyalgia and chronic fatigue syndrome  
Compositions and methods for alleviating the symptoms associated with chronic fatigue syndrome and fibromyalgia syndrome are provided. The compositions are based on use of a transdermal gel...
8999964 TGR5 modulators and methods of use thereof  
The invention relates to compounds of Formula (A): (A) or a salt, solvate, hydrate, or amino acid conjugate thereof. The compounds of formula A are TGR5 modulators useful for the prevention and...
8993551 Composition for the regulation of the human immune system and the prevention and treatment of diseases thereof  
A nutritional supplement composed of phytosterols, anti-oxidants, and other complexes, including essential fatty acids, amino acids, peptides, proline rich polypeptides and digestive enzymes is...
8987241 Time-release and micro-dose formulations for topical application of estrogen and estrogen analogs or other estrogen receptor modulators in the treatment of dry eye syndrome, and methods of preparation and application  
A topical application formulation of estrogen and estrogen analogs or other estrogen receptor modulators is disclosed for the treatment of primary or secondary dry eye syndrome (also known as...
8987240 Pharmaceutical compositions comprising estetrol derivatives for use in cancer therapy  
The present invention relates to a method of treating or preventing estrogen-suppressed tumors in a mammal, said method comprising the administration of a therapeutically effective amount of an...
8987236 Therapeutic uses for an aminosterol compound  
A pharmaceutical composition includes, as an active ingredient, a compound according to formula 1436 as shown in FIG. 1, or a pharmaceutically acceptable salt thereof, and a pharmaceutically...
8975243 Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract  
Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those...
8975246 Bile acid or bile salt fatty acid conjugates  
A method for treating a disease or disorder associated with altered glucose metabolism or insulin action in a subject in need thereof. The method includes administering to the subject a BAFAC...
8969330 Steroids as agonists for FXR  
The invention relates to compounds of formula (I): wherein R is ethyl, propyl or allyl, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula...
8969329 Allopregnanolone in a method for enhancing neurological function  
Neuro-enhancing agents, compositions and methods are disclosed herein. Preferred neuro-enhancing agents of the present invention include progesterone and metabolites of progesterone, such as...
8968763 Block biodegradable copolymers for medical devices  
Disclosed herein are implantable medical devices comprising controlled release biodegradable block copolymers or coated with controlled release block copolymers and at least one drug releasable...
8969326 Estrogen antagonists as treatments for sclerosing disorders  
The present invention relates to methods and compositions for treating a subject suffering from a sclerosing disorder, comprising administering, to the subject, an effective amount of an estrogen...
8957054 Pharmaceutical compositions  
Novel methods for treating or reducing the likelihood of acquiring symptoms or diseases due to the menopause, in postmenopausal women, particularly osteoporosis, vaginal atrophy and dryness,...
8957055 Aminoalkylsterol compounds with antitumoral and neuroprotective activity  
Sterol derivatives of formula (I) and a method for the production of the compounds, a medicament using one of the compounds and a pharmaceutical composition comprising the medicament.
8951996 17-hydroxyprogesterone ester-containing oral compositions and related methods  
The present invention provides for bioavailable oral dosage forms containing esters of 17-hydroxyprogesterone as well as related methods. The oral dosage forms can be formulated for pregnancy...
8951995 Use of 24-nor-UDCA  
The present invention relates to the use of nor-ursodeoxycholic acid for the manufacture of a drug for the treatment and/or the prevention of liver diseases, preferably chronic liver diseases.
8946199 Co-administration of steroids and Zoledronic acid to prevent and treat side effects from Zoledronic acid infusion  
Zoledronic Acid is used for treatment of hypercalcemia of malignancy, for the treatment of bone metastasis associated with malignancies such as prostate and breast cancer, for the prevention of...
8936809 Method for treating prostate diseases based on local delivery of active substances  
A method for treating prostate related diseases in a subject, the method comprising i) optionally administering to subject an initial boost dose of one or more active substances and/or prodrugs,...
8932614 Incorporation of particulate ceragenins in polymers  
A composite that includes a polymeric material having a void structure and particulate ceragenin material (i.e., ceragenin particles) associated with the void structure. The average particle size...
8933063 Preparation of a crystalline antibiotic substance  
The present invention relates to processes for the crystallisation and for the preparation and isolation of a novel crystalline form of fusidic acid, to the use of said processes in the...
8895541 Methods for inhibiting the development of huntington's disease  
This invention relates to Huntington's disease and more specifically to methods for inhibiting the development of or treating Huntington's disease by administering estrogen, testosterone,...
8895542 Medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer and a process to make it  
Disclosed is a medicinal cream that includes flisidic acid which is made in situ under an oxygen-free environment using sodium fusidate. The fusidic acid is made by dissolving the sodium fusidate...
8889662 Method to alter sex ratios in avian offspring  
The present invention includes methods of influencing the sex chromosome ovulated by a female bird and altering the sex ratio in avian offspring by altering the exposure of an ovulating female...
8883769 Methods for the treatment of fibromyalgia and chronic fatigue syndrome  
The invention relates to methods for the treatment of fibromyalgia and chronic fatigue syndrome by administration of a transdermally applied androgen composition. The treatment is both safe and...
8883770 Synthetic bile acid compositions and methods  
Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin...
8865197 Food formulation for aquatic animals with integrated targeted delivery of bioactive agents  
An encapsulated formulation for food and bioactive agent delivery to aquatic animals includes various combinations of nutrients, a digestion enhancer, bioactive agents, and a local absorption...
8865181 Extracting method of Antrodia cinnamomea  
An extracting method of Antrodia cinnamomea, being apt to improve extraction rate of dehydrosulphurenic acid, comprises: soaking a sample of raw Antrodia cinnamomea in a salt solution, with the...
8865693 Prevention of infection  
The invention relates to compounds and methods for the prevention and/or treatment of infection after stroke.
8865692 Compositions for the treatment of gastrointestinal inflammation  
Provided herein are methods for treating, preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for...
8835413 Sex steroid precursors alone or in combination with a selective estrogen receptor modulator and/or with estrogens and/or a type 5 cGMP phosphodiesterase inhibitor for the prevention and treatment of vaginal dryness and sexual dysfunction in postmenopausal women  
Novel methods for treating or reducing the likelihood of acquiring vaginal dysfunctions, more particularly vaginal dryness and dyspareunia, leading to sexual dysfunction and low sexual desire and...
8835414 Treatment of vaginal atrophy in women with cardiovascular pathology risk  
The present invention relates to the use of estriol in the preparation of a pharmaceutical formulation for vaginal administration with the capacity to self-limit the absorption of estriol, for the...
8815299 Method for obtaining a natural mixture of conjugated equine estrogens depleted in non-conjugated lipophilic compounds  
A method for obtaining an extract containing the natural mixture of conjugated equine estrogens by liquid-liquid extraction of the mixture of conjugated equine estrogens, wherein the mixture...
8809309 Use of 5α-androstane (alkyl)-3β,5,6β-triol in preparation of neuroprotective drugs  
Disclosed is the use of 5α-androstane(alkyl)-3β,5,6β-triol in preparing neuroprotective drugs. The compound has significant protective effect against neuron injuries caused by cerebral ischemia,...
8796249 TGR5 modulators and methods of use thereof  
The invention relates to compounds of Formula A: (A) or a salt, solvate, or hydrate thereof. The compounds of formula A are TGR5 modulators useful for the treatment of disease.
8790687 Triterpene compounds which are effective on improvement of brain function  
The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the...
8785426 Testosterone gel compositions and related methods  
Described are gel compositions containing active pharmaceutical ingredient such as testosterone, solvent, and thickener, the gel compositions being useful for transdermal administration of the...
8785423 Compositions and methods of inducing endoplasmic reticulum stress response for the treatment of cell proliferative diseases  
The present invention provides methods of inducing cell cycle arrest and/or cell growth inhibition, with the methods comprising administering to the cells an effective dose of the compounds of the...
8784857 Articles incorporating absorbent polymer and ceragenin compound  
An absorbent article includes an absorbent polymer and a ceragenin compound. The ceragenin compound has a sterol group and a plurality of cationic groups that mimic naturally occurring...
8778918 Use of 19 nor DHEA derivatives for enhancing physical performance  
A method is disclosed for administering a DHEA derivative or a physiologically acceptable salt, ester or ether thereof for one of decreasing body weight, reducing adipose tissue, increasing...
8765164 Poly(ester urea) polymers and methods of use  
The invention provides high molecular weight, crystalline or semi crystalline biodegradable and biocompatible poly(ester urea) (PEU) polymers useful for making vascular stents and hard tissue...
8754068 Modified C-3 betulinic acid derivatives as HIV maturation inhibitors  
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, modified C-3 betulinic acid and other structurally related...
8754069 Betulinic acid derivatives with antiviral activity  
Compounds of Formula I: that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.
8741882 Anti-diabetic compounds  
The preset invention relates to a new oral anti-diabetic compound prepared by synthesizing a steroid and a guanide or biguanide, which is eliminated via the hepatic route, instead of the renal...
8741880 Antiglucocorticoid therapy for the prevention of neurological damage in premature infants  
This invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used in methods for preventing neurological damage associated with glucocorticoid...
8729058 Methods and compositions for treating and preventing viral infections  
A method of treating or preventing a systemic viral infection in a mammal by administering a pharmaceutically acceptable composition selected from the group consisting of squalamine, an active...