Matches 151 - 200 out of 290 < 1 2 3 4 5 6 >
Match Document Document Title
4514386 Cream Preparation  
An antiinflammatory cream preparation which comprises an antiinflammatory substance hardly soluble in water in a base composition at a concentration of 0.05 to 1.5% by weight based on the...
4489071 Betamethasone dipropionate cream  
An elegant topical cream composition, containing betamethasone dipropionate, for the treatment of inflammation.
4489070 Betamethasone dipropionate cream  
Disclosed is an elegant formulation of betamethasone dipropionate useful as a topical anti-inflammatory product.
4478822 Drug delivery system utilizing thermosetting gels  
This invention relates to a unique drug delivery system for delivering drugs to a body cavity. The drug delivery system comprises a medicament and a polymer such that the drug delivery system is a...
4474753 Topical drug delivery system utilizing thermosetting gels  
This invention relates to a unique drug delivery system for application to the skin which drug delivery system is a liquid at room temperature, but when administered topically to the skin becomes a...
4466956 Method of therapy for oral herpes simplex  
There is disclosed a method for the treatment of oral herpes simplex that manifests itself as ulcerations and ulcers of the type that appear in or near the mouth or other mucous membranes or other...
4456602 Amine containing ester prodrugs of corticosteroids  
Novel solution stable ester prodrugs of corticosteroids of the formula ##STR1##
4428960 3-Amino-6-substituted thio-1-azabicyclo(3.2.0)hept-6-en-2-one-7-carboxylic acids  
Disclosed are 3-amido-6-substituted thio-1-azabicyclo[3.2.0]hept-6-en-2-one-7-carboxylic acids (I) and their pharmaceutically acceptable salts and esters which are useful as antibiotics ##STR1##...
4427671 Steroids esterified in position 17 and thioesterified in position 21, a process for preparing them and their use as medicaments  
Compounds of formula: ##STR1## wherein A and B each represent, independently of each other, a straight-chained or branched alkyl group having from 1 to 6 carbon atoms or a phenyl group optionally...
4427649 Pharmaceutical compositions  
Pharmaceutical liposome compositions containing an anti-inflammatory steroid derivative bearing a lipophilic substituent, for example cortisol 21-hexadecanoate. Method of treatment of inflammation...
4423040 Vehicle composition containing 1-substituted azacyclohexan-2-ones  
Compositions useful for carrying physiologically active agents such as therapeutic agents through skin and other body membranes comprising the agent and an effective, non-toxic amount of a compound...
4414209 Micronized aerosol steroids  
An antiinflammatory steroid exhibiting a tendency to crystal growth in suspension in aerosol propellants is contacted with a halogenated hydrocarbon to form a crystalline solvate, which, after...
4407792 Sustained release ophthalmic drug dosage  
The present invention is directed to an aqueous dispersion of an ophthalmic drug and a high molecular weight polymer which forms a highly viscous gel and can be used to prolong the duration of...
4406883 Controlled release suppositories consisting essentially of a linear polymer particularly, polyvinyl pyrrolidones  
A slow-release suppository is provided. The slow-release suppository comprises a linear polymer, water and a therapeutically active ingredient. In particular, in accordance with the present...
4390533 Steroids and process for preparing the same  
The present invention relates to 2-chloro-6β-fluoro-pregna-1,4-diene-3,20-diones having good anti-inflammatory activity, to processes for their preparation and pharmaceutical compositions thereof.
4389393 Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose  
A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration,...
4383992 Water-soluble steroid compounds  
Beta-cyclodextrin forms a water-soluble complex or inclusion compound with steroid compounds having a molecular structure smaller than the interior cavity in the doughnut-shaped molecular structure...
4377575 Corticoid-17-(alkyl carbonates) and process for their manufacture  
What is disclosed are steroid-21-halogeno-17-(alkyl carbonates), useful as medicaments for the treatment of inflammatory dermatoses, and a method for making them.
4370322 Topically administrable pharmaceutical compositions containing anti-inflammatory steroids  
Pharmaceutical compositions such as ointments and creams are provided by admixture of anti-inflammatory steroids active on topical application with a liquid oily phase containing at least one oil...
4361559 Antiinflammatory 17,17-bis (substituted thio) androstenes  
3-Ketoandrostenes having in the 17-position the substituents R 1 --S-- and R 2 --S-- wherein R 1 and R 2 are the same or different and each is alkyl, cycloalkyl or aryl, have antiinflammatory...
4361558 Halogenated steroids  
Novel halogenated steroids of the formula ##STR1## in which X represents a halogen atom having a maximum atomic number of 17, Y represents a hydrogen atom or hydroxyl, and R represents an...
4350690 Steroid composition  
A steroid pharmaceutical composition for administration as an enema to patients for treatment of inflammatory bowel disorders comprises a liquid suspension of total volume from about 50 to about...
4344940 Steroid formulation containing dipotassium EDTA  
A steroid formulation is provided which is preferably in the form of a lotion or cream and contains a steroid, such as halcinonide, a polyol vehicle therefor, such as polyethylene glycol, and...
4343798 Topical antimicrobial anti-inflammatory compositions  
Topical antimicrobial anti-inflammatory compositions, having a pH no greater than about 5, containing C 5 -C 12 fatty acids together with a corticosteroid component, are disclosed. The method of...
4340594 Fat emulsion containing steroid  
A fat emulsion containing a steroid having an anti-inflammatory activity, comprising an effective quantity of a steroid having an anti-inflammatory activity, 5 to 50% (W/V) of soybean oil, a...
4335121 Androstane carbothioates  
Compounds of the formula ##STR1## wherein R 1 represents a fluoro-, chloro- or bromo-methyl group or a 2'-fluoroethyl group, R 2 represents a group COR 6 where R 6 is a C 1 -3 alkyl group or OR...
4333927 Skin preparation  
Skin preparations containing a phosphatide, a topical corticosteroid, and butylhydroxyanisole and/or butylhydroxytoluene, which may be in the form of an aqueous or oily mixture, non-aqueous,...
4312865 Medication having penetration through cutaneous surfaces into articular and muscular areas  
A medication that penetrates the surface of the skin is provided. The articular and muscular areas subject to discomfort may be relieved by the topical application of the medication. The medication...
4305936 Topical corticosteroid formulations  
This present invention relates to a solution for topical or local application comprising at least one corticosteroid; from about 1% to 4% by weight of solubilization agents consisting essentially...
4304765 Ocular insert housing steroid in two different therapeutic forms  
An ocular insert and an ocular composition are disclosed. The insert and the composition comprises a steroid in two different forms.
4303654 Novel 21-chloro-20-acetylenic steroids  
Novel 21-chloro-20-acetylenic steroids of the formula ##STR1## wherein R 1 is alkyl of 1 to 3 carbon atoms, R is selected from the group consisting of hydrogen and acyl of an organic carboxylic...
4301145 Antiseptic skin cream  
An antiseptic skin cream is taught including a base composition comprising a decolorizing agent, a solvent, a solvent humectant, a preservative, an emulsifier and an ointment base to which is added...
4299828 Corticosteroid stick formulations  
Corticosteroid formulations in the form of a lipophilic stick are provided which are used as anti-inflammatory agents; the lipophilic stick includes the corticosteroid, such as halcinonide or...
4298604 Clotrimazole-betamethasone dipropionate combination  
Antifungal compositions comprising clotrimazole and betamethasone dipropionate are disclosed.
4296109 Corticoid 21-sulfopropionates and the salts thereof, a process for the production thereof and pharmaceutical preparations thereof  
Corticoid 21-sulfopropionates of the formula ##STR1## wherein St is a steroid nucleus of a corticoid having anti-inflammatory activity, and the salts thereof with physiologically acceptable bases,...
4294829 Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa, and method for administration thereof  
A powdery pharmaceutical composition and a powdery preparation in unit dosage form for application to the mucosa of the nasal cavity, at least about 90% of which consists of particles having an...
4294852 Skin treating compositions  
The invention relates to a composition for treatment and control of excessively thickened, inflexible and scaly stratum corneum which often fissures into the dermis resulting in foci of bleeding...
4289763 Novel corticoids, the preparation thereof and the use thereof  
Corticoids of the formula ##STR1## wherein X is fluorine, chlorine and R is hydrogen, C 1 -6 alkanoyl, benzoyl or --OCO--A--COOH wherein A is a carbon-to-carbon bond or a C 1 -6 hydrocarbon...
4285937 Novel androstadiene-17-carboxylic acid esters  
The invention provides novel esters of androstadiene 17-carboxyclic acids of the formula ##STR1## wherein R' represents a hydroxyl group which is esterified with a carboxyclic acid having not more...
4284630 Stabilized water-in-oil emulsions  
Stable water-in-oil emulsions useful as vehicles for cosmetics or for therapeutic compositions to be topically applied are disclosed. The emulsions utilize a concentration of from 0.2 to 2% by...
4278669 3-Oxo-4-halo-16β-methylandrost-4-ene 17β-carboxylic acids and esters  
Certain 3-oxoandrost-4-ene and 3-oxoandrosta-1,4-diene 17β-carboxylic acids (and esters thereof) substituted at the 4-position with a fluoro or chloro, optionally substituted at the 6- position...
4273770 4-Halo steroids  
Certain pregn-4-ene-3,20-diones or pregn-1,4-diene-3,20-diones 4-substituted with a fluoro or chloro are useful as topical anti-inflammatory steroids. These compounds are substituted at 9α with...
4267173 Use of 6β-fluoro-7α-halogenocorticoids as topical anti-inflammatories and pharmaceutical formulations useful therefor  
Described is the use of 6β-fluoro-7α-halogeno-1,4-pregnadiene-17α,21-diol-3,20-di ones and their esters as topical anti-inflammatory agents, and pharmaceutical formulations thereof useful...
4261986 4-Halo etianic acids and derivatives thereof  
Certain 3-oxoandrost-4-ene and 3-oxoandrosta-1,4-diene 17β-carboxylic acids and esters substituted at the 4-position with a fluoro or chloro and optionally substituted at the six position with...
4261984 17β-thiocarboxylic acid esters of 3-oxo-4-halo-16β-methylandrost-4-enes  
Certain 3-oxoandrost-4-ene and 3-oxoandrosta-1,4-diene 17β-thiocarboxylic acid esters substituted at the 4-position with a fluoro or chloro, optionally substituted at the 6- position with fluoro...
4260605 Novel alkylated pregnanes, processes for their preparation and pharmaceutical compositions containing same  
The present invention relates to novel 21-alkylated steroids of the pregnane series having the formula: ##STR1## wherein R 1 =alkyl (1-4 C); R 2 =carboxyacyl (1-18 C); X=H, F or Cl; Y=O, H(OH),...
4255415 Polyvinyl alcohol ophthalmic gel  
An ophthalmic gel having an improved intensity and duration of the biological response is provided by utilizing a polyvinyl alcohol-sodium borate gel buffered to a pH of 6.5-8.5.
4242334 Corticoid 17-(alkyl carbonates) and processes for their preparation  
What is disclosed is corticoid 17-(alkyl carbonates) of the formula ##STR1## as defined in the specification, which compounds can be used in veterinary therapy and human therapy, in the form of...
4221787 Esteramide prodrugs of anti-inflammatory corticosteroids  
Transient, C-21 and/or C-17 esteramide prodrugs of the anti-inflammatory corticosteroids, prepared by esterification of hydroxy steroids, are disclosed.
4207316 Novel 17-substituted 11 β-hydroxy steroids of the pregnane series, their manufacture, preparation and use  
Corticoids of the formula ##STR1## wherein represents a single bond or a double bond; X is hydrogen, fluorine, chlorine or methyl; Y is hydrogen and Z is hydrogen, fluorine or chlorine, or ...
Matches 151 - 200 out of 290 < 1 2 3 4 5 6 >