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6642236 |
Methods for prophylactic treatment of cardiovascular disease with inhibitor of cortisol synthesis
Ketoconazole and related substances which are inhibitors of cortisol synthesis can be administered to prophylactically treat cardiovascular disease, such as coronary artery disease, artiosclerotic...
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6642219 |
Progestogen-antiprogestogen regimens
An estrogen-free contraceptive is provided which does not have the bleeding-related drawbacks of conventional progestogen-only pills. Thus the invention is a contraceptive kit comprising a combined...
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6620803 |
Cosmetic or dermatological use of 7-hydroxylated steroids
A method of preventing the cutaneous effects of aging and/or the effects of UV irradiation on the skin, said method comprising applying to the skin a composition comprising at least one compound...
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6620802 |
Methods of treating mild cognitive impairment using a glucocorticoid-specific receptor antagonist
This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used...
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6613758 |
Method for treating osteoporosis in castrated prostatic cancer patients
The present invention provides a method for preventing or treating osteoporosis in a castrated prostatic cancer patient, by administering to the patient an amount of from 10 mg to 300 mg...
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6610674 |
Method of treating inflammatory conditions with progesterone analogs
The present invention provides methods for treating inflammatory conditions, including but not limited to, inflammatory bowel disease (ulcerative colitis, Crohn's disease, and proctitis), other...
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6610675 |
Inactive metabolite approach to soft drug design
The invention provides novel soft steroidal anti-inflammatory agents, pharmaceutical compositions containing said agents, and methods of administering same to mammals in the treatment of...
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6605605 |
Estrogenic substances combined with cruciferous indole compounds
Provided herein are medicinal compositions of matter that comprise an estrogenic medication component and a cruciferous indole component (indole 3-carbinol, diindolylmethane, or any derivative...
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6593316 |
Use of &Dgr 5-androstene-3βol-7,17-dione in the treatment of lupus erythematosus
Lupus erythematosus can be treated by administering therapeutic amounts of Δ5-androstene-3β-ol-7,17-dione and metabolizable precursors thereof, such as Δ5-androstene-3β-acetoxy-7,17-dione,...
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6593320 |
Flocculated suspension of megestrol acetate
A novel oral pharmaceutical composition in the form of a stable flocculated suspension in water is described as comprising: megestrol acetate; at least one compound selected from the group...
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6589945 |
Use of sterolsulfates as active substances for producing means to inhibit serin proteases
A process for treating human skin by inhibiting serine protease formation involving contacting the skin with a composition containing a sterol sulfate.
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6586417 |
Ester and ether derivatives of 4-hydroxy 4-androstene-3,17-dione and a method for the regulation of athletic function in humans
This invention relates to a method of administering an effective amount of at least one of the ester or ether derivatives of 4-hydroxy 4-androstenedione for the regulation of athletic function in...
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6583129 |
Administration of non-oral androgenic steroids to women
The present invention provides compositions, methods, and kits for improving health in a woman having elevated SHBG levels, or who is receiving oral estrogen supplementation, by non-orally...
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6579864 |
3-methylene steroid derivatives
The invention concerns a 3-methylene steroid derivative having general formula (1) wherein R 1 is H or together with R 3 forms a β-epoxide or R 1 is absent if there is a 5-10 or 4-5 double...
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6569845 |
Neovascularization inhibitor containing dienogest as the active ingredient
A suppressing agent of angiogenesis that contains dienogest or a solvate thereof as the effective ingredient, and a prophylactic and/or therapeutic agent of angiogenic diseases, utilizing a novel...
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6562790 |
Hormone therapy methods and hormone products for abating coronary artery blockage
Methods for abating coronary artery blockage in human subjects include administering a combination of natural hormones including human growth hormone with sufficient T3 thyroid supplement to...
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6555530 |
Use of estrogens and delta-gonadien-21-Ol-3,20-diones for treating insulin dependent and non-insulin dependent diabetes
Analysis of full-blood glucose, serum insulin, serum triglycerides and total serum cholesterol were performed. Glucose levels in blood samples from the oral glucose tolerance test were used for...
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6548087 |
Nutritional supplement
A dietary supplement for improvement of sexual dysfunction without resulting in undesirable side effects which occasionally accompany the use of prescription medicaments used for this purpose. The...
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6544550 |
Medicaments for gastrointestinal disorders
The invention relates to the co-administration in human or veterinary medicine of 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)me
thyl]-4H-carbazol-4-one or a physiologically...
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6544971 |
Method of increasing alertness by administration of a vomeropherin, and vomeropherin-emitting alarm devices
A method of increasing alertness in an individual by administering an effective amount of an alertness-increasing vomeropherin to the individual; and an alarm device that, when activated, emits an...
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6541465 |
Orally active androgens
Novel, orally active androgens are 7α-substituted Δ 14 -nandrolone derivatives. The compounds satisfy the general formula: wherein R 1 is O, (H,H), (H,OR), NOR, with R being hydrogen, (C 1-6...
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6531461 |
Medicament for the treatment of diabetes
A series of compounds of general structure I and metal salts thereof. These compounds are useful in the treatment of diabetes mellitus and associated conditions when administered in an effective...
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6524623 |
Therapeutic compositions and methods of use thereof
A therapeutic composition and a method of using the composition are provided. The composition includes an osmotic agent and an active agent. The osmotic agent improves the delivery of the active...
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6514980 |
Nucleoside analogs in combination therapy of herpes simplex infections
A pharmaceutical product comprising a nucleoside analogue active against herpes simplex virus, such as acyclovir/valaciclovir or penciclorivir/famciclovir, and an immunosuppressant, as a combined...
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6506742 |
Soluble contraceptive liquid formulation
This invention provides a convenient process for preparing an oral contraceptive liquid formulation having improved solubility, bioavailability and stability useful as a reference standard.
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6503894 |
Pharmaceutical composition and method for treating hypogonadism
A pharmaceutical composition useful for treating hypogonadism is disclosed. The composition comprises an androgenic or anabolic steroid, a C1-C4 alcohol, a penetration enhancer such as isopropyl...
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6495534 |
Stabilized aqueous suspensions for parenteral use
A pharmaceutical aqueous suspension formulation for parenteral administration having substantially stabilized pH, comprising a biologically active compound and a pH controlling effective...
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6489313 |
Memory by the administration of &Dgr 5-androstene-3β-ol-7,17-dione and 3β esters
The memory of a healthy mammal and the memory of a mammal with age impaired memory can be improved by administering an effective amount of Δ5-Androstene-3β-ol-7,17-dione and 3β esters thereof.
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6486147 |
Cosmetic composition containing a steroid and a 2-alkylalkanol or an ester thereof
A composition including at least one steroid chosen from DHEA and/or a biological precursor and/or a chemical or metabolic derivative of the latter, characterized in that it additionally comprises...
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6482813 |
Steroids substituted at the 11-position, process for their preparation, their use as medicament and the pharmaceutical compositions containing them
Compounds of formula for treating osteoporosis with minimal estrogenic activity are disclosed.
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6476011 |
Methods for introducing an estrogenic compound
The invention pertains to methods for introducing an estrogenic compound into a subject in need thereof involving administering an effective amount of a ring system compound having the formula (II)...
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6468994 |
Budesonide particles and pharmaceutical compositions containing them
The invention provides finely divided, substantially crystalline particles of budesonide characterized in that they are substantially smooth and having a BET value of from 1 to 4.5 m2/g, a process...
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6465446 |
Treatment of dermatitis by the topical application of &Dgr 5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof
Dermatitis can be treated by the administration of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof, such as Δ5-androstene-3β-acetoxy-7,17 dione, to the skin.
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6458778 |
Estradienes
This invention provides estra-5(10),7-dien-3β-ol-17-one or a pharmaceutically acceptable salt of its 3-sulfate ester, estra-5(10),7-dien-3β-ol-17-one 3-glucuronide or a pharmaceutically...
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6432938 |
19-nor-cholane steroids as neurochemical initators of change in human hypothalamic function
The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human vomeropherin, e.g. a 19-nor cholane steroid, or a...
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6432439 |
O/W emulsion composition
An O/W emulsion composition comprising fluorometholone or clobetasone butyrate, a phospholipid, an oil, a nonionic water-soluble cellulose derivative, and water. The O/W composition has advantages...
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6432939 |
17a-hydroxy-4-androstene-3-one and derivatives thereof
This invention describes 17α-hydroxy-4-androstene-3-one and its derivatives of the general formula I a method for producing these compounds and pharmaceuticals containing these compounds. The...
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6423701 |
Water soluble amine esters of testosterone for intranasal administration
The present invention provides novel water soluble testosterone analogs. These testosterone analogs are suitable for intranasal administration to patients requiring increased plasma testosterone...
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6423698 |
Combination therapy for the prophylaxis and/or treatment of benign prostatic hyperplasia
A combination therapy for the prophylaxis and/or treatment of benign prostatic hyperplasia in susceptible warm-blooded animals which comprises administering a combination of two or more compounds...
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6417179 |
Ear wax solution
An ear wax solution includes a detergent which is effective to treat the ear wax by a mechanism involving at least one of dissolving the ear wax, softening the ear wax, and reducing the attachment...
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6399084 |
Method for diminishing wrinkles and fine lines of the skin by the topical application of &Dgr 5-androstene-3β-ol-7, 17 dione and metabolizable precursors thereof
Wrinkles and fine lines occurring on human skin can be diminished by the administration of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof, such as...
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6399085 |
Method of moisturizing the skin by the topical application of &Dgr 5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof
Human skin can be moisturized by the administration of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof, such as Δ5-androstene-3β-acetoxy-7,17 dione.
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6372732 |
Use of delta5-androstene-3beta-ol-7, 17-dione in the treatment of lupus erythematosus
Lupus erythematosus can be treated by administering therapeutic amounts of delta-5-androstene-3-beta-ol-7,17-dione and its metabolizable precursors, which are not appreciably metabolized in vivo to...
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6369115 |
Stabilized powder formulations
A dry powder formulation for treatment of pulmonary conditions, via inhalation, includes an effective amount of formoterol or a salt or solvate thereof, in a dry powder form, an effective amount of...
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6355630 |
Estra-1,3,5(10)-triene-7α-thioethers
This invention provides estrogens and antiestrogens of formula I having the structure wherein X, Y, Z, and R are as defined hereinbefore in the specification, or a pharmaceutically acceptable...
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6352722 |
Derivatized carbohydrates, compositions comprised thereof and methods of use thereof
Derivatized carbohydrates are provided which can be used to form a variety of materials including solid delivery systems. The derivatized carbohydrates are generally carbohydrates, wherein at least...
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6352980 |
Estrenes for inducting hypothalamic effects
The invention relates to estrene steroids, which bind to neuroepithelial receptors. The steroid is preferably administered in the form of a pharmaceutical composition containing one or more...
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6333317 |
Regulation of amyloid precursor protein (APP) expression by administration of an estrogenic compound
It has been discovered that lipophilic hormones that interact with cytosolic or nuclear receptors regulate APP expression and synthesis, through modification of APP mRNA stability and/or regulation...
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6313180 |
Steroid compounds having contraceptive and anti-osteoporosis activity
The invention relates to a steroid compound having the formula (I) ##STR1## comprising a ring E, said ring sharing carbon atoms at position 16 and 17 with the five-membered ring D and being α with...
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6306846 |
Anti-inflammatory and anti-ulcer compounds and process
Disclosed herein are anti-inflammatory and anti-ulcer copper coordination compounds and a process for using them in the treatment of arthritis and gastrointestinal ulcers in animal bodies. The...
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