|
Match
|
Document |
Document Title |
|
|
6969708 |
Process for the preparation of a high purity composition comprising (7α, 17α)- 17-hydroxy- 7-methyl- 19-nor-17-pregn-5(10)-en-20-yn-3-one
The invention pertains to a process for the preparation of a high purity composition of (7α, 17α)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn-3-o
ne. The process provides for a composition...
|
|
|
6964954 |
Use of DHEA derivatives on keratinous substances
Methods of improving the appearance of keratinous substances using at least one DHEA derivative such as the skin, hair, eyelashes and/or nails, in particular for preventing or treating cutaneous...
|
|
|
6964953 |
Methods for treating stress disorders using glucocorticoid receptor-specific antagonists
This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used...
|
|
|
6962908 |
Oral pharmaceutical products containing 17 β-estradiol-3-lower alkanoate, method of administering the same and process of preparation
A pharmaceutical dosage unit for oral administration to a human female comprising a therapeutically effective amount of 17β-estradiol-3-lower alkanoate, most preferably 17β-estradiol-3-acetate,...
|
|
|
6953586 |
Growth promoting pharmaceutical implant
A combination growth promoting pharmaceutical pellet system which delivers doses of both a growth stimulating pharmaceutical agent and a supplemental agent that enhances the growth produced by the...
|
|
|
6949533 |
6,7-Oxygenated steroids and uses related thereto
Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of...
|
|
|
6930125 |
Airway alkalinization as a therapy for airway diseases
The present invention relates to a method of treating asthma by raising the pH of the airways of an individual. The effect can be mediated directly by administering a pharmaceutically acceptable...
|
|
|
6924274 |
Use of Δ5-androstene-3β-ol-7,17-dione in the treatment of lupus erythematosus
Lupus erythematosus can be treated by administering therapeutic amounts of Δ5-androstene-3β-ol-7,17-dione and metabolizable precursors thereof, such as Δ5-androstene-3b-acetoxy-7,17-dione, which...
|
|
|
6906049 |
Contraceptive medicine based on a progestational agent and an oestrogen and preparation method
The present invention relates to the field of chemistry and more particularly to that of therapeutic chemistry. The invention relates more particularly to novel contraceptive compositions formed...
|
|
|
6903084 |
Steroid sulphatase inhibitors
A method of inhibiting steroid sulphatase activity in a subject in need of same is described. The method comprises administering to said subject a steroid sulphatase inhibiting amount of a ring...
|
|
|
6900239 |
Tumor chemopotentiation using isocoumarin derivatives
A method for enhancing the efficacy of chemotherapy in the treatment of cancer in animals, particularly humans, is provided wherein isocoumarin derivatives that exhibit unique chemopotentiation...
|
|
|
6884793 |
Combination preparation for contraception based on natural estrogens
The combination preparation for contraception includes from 2 to 4 first stage daily dosage portions each including an effective amount of at least one natural estrogen as sole active ingredient,...
|
|
|
6881728 |
14-β, 17-α-hydroxymethylandrostane derivatives as androgens
Androgenic steroids having a (14β,17α-)-17-(hydroxymetheyl) configuration, useful for the preparation of male contraceptives and pharmaceutical formulations for the treatment of androgen...
|
|
|
6858597 |
Halogenated sulphamate-, phosphonate-, thiophosphonate-, sulphonate- and sulphonamide- compounds as inhibitors of steroid sulphatase
A compound is described. The compound has the formula (Ia) as presented in the FIG. 1; wherein: X is a ring having at least 4 atoms in the ring; K is hydrocarbyl group; Rh1 is an optional halo...
|
|
|
6852710 |
2-alkoxyestradiol analogs with antiproliferative and antimitotic activity
The application discloses novel 2-alkoxyestradiol analogs which exhibit anti-proliferative properties, and methods of making and using such compounds to inhibit undesired cell proliferation and...
|
|
|
6846812 |
7-Oxo-DHEA compounds for treating keratinous conditions/afflictions
7-Oxo-DHEA derivatives, various of which are themselves novel compounds, are well suited for cosmetically/therapeutically treating adverse conditions/afflictions of a keratinous substrate/material,...
|
|
|
6844333 |
Method of treating atherosclerosis
The present invention relates to a method of treating atherosclerosis, and to compounds and compositions suitable for use in such a method.
|
|
|
6844334 |
(3) and (6) substitued estrogenic compounds
Novel estrogenic compounds of Formula I are provided.
wherein the bond represented by the wavy line may be a single or double bond such that when the wavy line is a single bond, R 1 is...
|
|
|
6844320 |
Treatment of preeclampsia, toxemia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor
Preeclampsia and preterm labor in a pregnant female mammal are treated by administering thereto a combination of a progestin and a nitric oxide synthase substrate, a nitric oxide donor or both,...
|
|
|
6841548 |
Pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives
The invention concerns pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives as active ingredients which carry a group of the general formula
|
|
|
6831073 |
Hormonal composition consisting of an oestrogen compound and of a progestational compound
A method of treating estrogenic deficiencies in women while further avoiding the appearance of osteoporosis, withdrawal bleeding and cardiovascular diseases in post-menopausal women without any...
|
|
|
6821961 |
Monounsaturated fatty acids of at least 20 carbon atoms and perhydrocyclopentanophenanthrene nucleus combination molecules and their use as weight-loss agents
The pharmaceutical and/or cosmetic compositions for treatment of obesity and/or overweight contain an effective amount of a fatty-acid monoester of an estrogen and a fatty acid wherein the estrogen...
|
|
|
6818636 |
B-ring estratrienes
This invention provides 3β-hydroxy-5,7,9-estratriene-17-one and a pharmaceutically acceptable salt of its 3-sulfate ester, which is useful as an estrogen.
|
|
|
6803060 |
Composition to boost libido
There is provided a natural composition for boosting the libido of an individual, the composition including an effective amount of an aphrodisiac and a compound to increase blood flow to the pelvic...
|
|
|
6797282 |
Combination progestin oral contraceptive regimen
An oral contraception regimen which comprises sequentially administering two or more progestational agents exhibiting different effects on the human endometrium in combination with an estrogen. The...
|
|
|
6794374 |
Use of &Dgr 5-androstene-3β-OL7,17-dione in the treatment of arthritis
Arthritis can be treated by administering therapeutic amounts of Δ5-androstene-3β-ol-7,17-dione and metabolizable precursors thereof, such a Δ5-androstene-3β-acetoxy-7,17-dione, which are...
|
|
|
6787529 |
Topical composition
The present invention relates to a pharmaceutical gel composition for application on skin, said composition comprising at least one vitamin D or vitamin D analogue and at least one corticosteroid...
|
|
|
6787531 |
Pharmaceutical composition for use as a contraceptive
A pharmaceutical composition comprises, as a first active agent, 6β,7β;15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17-c
arbolactone (drospirenone) in an amount corresponding to a daily...
|
|
|
6780854 |
Orally active androgens
Novel, orally active androgens are 7α-substituted Δ 14 -nandrolone derivatives. The compounds satisfy the general formula: wherein R 1 is O, (H,H), (H,OR), NOR, with R being hydrogen, (C 1-6...
|
|
|
6777389 |
Cosmetic or dermatological use of 7-hydroxylated steroids in combination with elastin derived peptides
The present invention is directed to a composition and method for enhancing the appearance of skin or tissue. The invention is preferably a combination of elastin-derived peptides and steroidal...
|
|
|
6767902 |
Androgen as a male contraceptive and non-contraceptive androgen replacement
The present invention relates to methods of providing male contraception using a specified androgen without the need of a separate sterilizing agent. The invention also describes methods for...
|
|
|
6759408 |
Combination regimens using progesterone receptor modulators
This invention relates to cyclic combination therapies and regimens utilizing substituted indoline derivative compounds which are antagonists of the progesterone receptor having the general...
|
|
|
6759400 |
Meiosis regulating compounds
Certain compounds, structurally related to natural compounds which can be extracted i.a. from bull testes and from human follicular fluid, can be used for regulating the meiosis in oocytes and in...
|
|
|
6756366 |
Orally active androgens
Orally Active androgens are derivative of 7α-methyl-19-nortestosterone. The compounds satisfy formula (I) wherein R 1 is O, (H,H), (H,OR), NOR, with R being hydrogen, (C 1-6 )alkyl, or (C 1-6...
|
|
|
6753326 |
14, 15-.α.-methylene equilenine derivatives, methods for producing the same and medicaments containing them
Described are novel equilenin derivatives of general formula I methods for producing the same and medicaments containing these compounds. The new compounds have antioxidative activity and are...
|
|
|
6753013 |
Pharmaceutical composition
A pharmaceutical composition for dermal use, wherein the composition has a first pharmacologically active component A consisting of at least one vitamin D or vitamin D analogue, and a second...
|
|
|
6740646 |
Bioavailable prodrugs of androgenic steroids and related method
A compound is provided for increasing the concentration of a parent androgen in a subject in vivo. The parent androgen has a skeletal structure including a 1 position and a 17 position, a...
|
|
|
6723715 |
14, 15-cyclopropanosteroids of the 19-norandrostane series, method for producing said compounds and pharmaceutical preparation containing said compounds
The invention relates to the new 14,15-cyclopropanoandrosteroids of the 19-norandrostane series of the general formula (I) their synthesis and to pharmaceutical compositions containing these...
|
|
|
6710039 |
Unsaturated 14,15-cyclopropane-androstanes, a method for their production and pharamceutical compositions containing these compounds
The invention relates to new unsaturated 14,15-cyclopropano-androstanes of the general formula (I) to their synthesis and to pharmaceutical compositions, containing these compounds. The...
|
|
|
6706700 |
14β,15β-methylene-17α-hydroxymethyl-androgens
The disclosed invention relates to the unexpected finding of novel steroids which are characterized by a 14β,15β-cyclopropane ring and a 17α hydroxymethyl group. These steroids according to the...
|
|
|
6706701 |
6, 7-oxygenated steroids and uses related thereto
Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of...
|
|
|
6670350 |
Method of administering dienogest in high dosages to reduce the body of the breast and pharmaceutical composition for same
A method of administering dienogest to a women in high dosages for reducing the body of the breast is described. The dosage should be at least ten times the effective dosage for inhibiting...
|
|
|
6670349 |
Composition & method for altering levels of or sensitivity to adenosine with a dehydroepiandrosterone &/or a ubiquinone
A method of treating adenosine depletion in a subject in need of such treatment is disclosed. The method comprises administering to the subject folinic acid or a pharmaceutically acceptable salt...
|
|
|
6667026 |
Allergic contact dermatitis treatment and composition therefor
A topical composition is disclosed for reducing a urushiol-induced allergic response and the dermatitis associated therewith. The composition is a preparation having an acorn derivative and a...
|
|
|
6660726 |
Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
Novel estrogenic compounds of Formula I are provided. wherein the bond represented by the wavy line may be a single or double bond such that when the wavy line is a single bond, R 1 is selected...
|
|
|
6656970 |
Method and compositions for solubilization of pentacyclic triterpenes
The present invention provides compositions and methods for the solubilization of poorly soluble drugs such as triterpenes like betulinic acid and/its derivatives in pharmaceutically acceptable...
|
|
|
6656505 |
Method for forming an aqueous flocculated suspension
An aqueous pharmaceutical composition suitable for oral delivery has an insoluble active substance and a wetting agent in liquid suspension. The composition contains floccules of the active...
|
|
|
6645954 |
Compositions comprising ethisterone or its derivatives
Treatment of androgen deficiency using a pharmaceutically effective dose of ethisterone or an ethisterone derivative such as Danazol. In particular, androgen deficiency in the aging male, also...
|
|
|
6645953 |
Meiosis regulating compounds
Sterol derivative compounds, structurally related to natural compounds which can be extracted from bull testes and from human follicular fluid, useful for regulating meiosis in oocytes and in male...
|
|
|
6641800 |
Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane
Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer...
|