Matches 101 - 150 out of 468 < 1 2 3 4 5 6 7 8 9 10 >
Match Document Document Title
6228850 Antiangiogenic activity of betulinic acid and its derivatives  
Use of betulinic acid and/or its derivatives for inhibiting and/or preventing angiogenesis is described. Compositions containing betulinic acid derivatives with or without betulinic acid can be...
6221377 Administration media for analgesic, anti-inflammatory and anti-pyretic drugs containing nitrous oxide and pharmaceutical compositions containing such media and drugs  
Administration mediums comprising solutions of nitrous oxide in water, alcohols, ethers or oils, and optionally including essential fatty acids or C 1 -C 6 alkyl esters thereof enhance the action...
6218435 Reduction of hair growth  
A method of reducing hair growth in a mammal includes applying, to an area of skin from which reduced hair growth is desired, a dermatologically acceptable composition containing a suppressor of...
6187750 Method of hormone treatment for patients with symptoms consistent with multiple sclerosis  
A method for treating patients having symptoms consistent with multiple sclerosis comprising administering a regimen of doses of human growth hormone of less than 0.5 mg/day. In one aspect, the...
6180682 Buccal drug delivery system for use in male contraception  
A buccal dosage unit is provided for administering a contraceptive composition to fertile mammalian males. The buccal dosage unit comprises a an androgenic agent and a progestin in a polymeric...
6177418 Tetracyclic triterpenes as cholesterol-lowering and anti-atherosclerosis agents  
6172052 17β-acyl-17α-propynyl-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties  
The invention is directed to a novel class of 17β-acyl-17β-propynyl steroids which exhibit potent antiprogestational activity.
6153607 Non-preserved topical corticosteroid for treatment of dry eye, filamentary keratitis, and delayed tear clearance (or turnover)  
A preservative-free composition containing an effective amount of a corticosteroid in an aqueous carrier to treat a dry eye condition. The composition may be provided as a part of a therapeutic...
6153606 Memory enhancement by the administration of Δ5-androstene-3β-ol-7,17-dione and 3β esters thereof  
The memory of a healthy mammal and the memory of a mammal with age impaired memory can be improved by administering an effective amount of Δ5-Androstene-3β-ol-7,17-dione and 3β esters thereof.
6147066 Use of antimineralocorticoid compounds against drug withdrawal syndrome  
Compounds having antimineralocorticoid activity suitable for preparing drugs for treating or preventing conditions related to drug dependence or to the spontaneous or induced withdrawal syndrome...
6147065 14-α, 17-α-C.sub.2 bridged norprogesterone derivatives  
Described are 14,17-C 2 -bridged steroids of the formula (I) defined in the specification. The compounds are available, even after peroral administration, with high gestagenic action and are...
6143736 Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series  
Methods, compositions, and compounds for modulating the GABA A receptor-chloride ionophore complex to alleviate stress, anxiety, seizures, mood disorders, PMS and PND and to induce anesthesia.
6143737 Progesterone analogs to reverse multidrug resistance  
The present invention is directed to compounds of formula I ##STR1## wherein the substituents are as defined in the specification. Also disclosed are compositions and method of use of the compounds.
6140316 Estrene steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions  
The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human semiochemical, e.g. an Estrene steroid, or a pharmaceutical...
6140315 Therapeutic uses of goserelin acetate  
A method of decreasing atherosclerosis and its complications, such as myocardial infarction, stroke and peripheral vascular disease, wherein the method involves administering to a human or an...
6117860 Steroids as neurochemical stimulators of the VNO to treat paroxistic tachycardia  
The invention relates to a method of alleviating the symptoms of PMS and anxiety. The method comprises nasally administering a steroid which is a human vomeropherin, such that the vomeropherin...
6113949 Weight control product and method of treating hyperlipidemia and increasing vigor with said product  
This invention relates to a weight control composition, preferably in the form of a capsule or tablet, comprising a mixture of guggul extract and at least one phosphate salt selected from calcium...
6114319 Compositions containing difluprednate  
The present invention relates to a liquid composition comprising difluprednate, oil, water and an emulsifier. The composition of the present invention has superior antiinflammatory action and...
6107276 Pharmaceutical compositions including a drug, a cross-linked polymeric substance, an oil, and a surface active agent  
The pharmaceutical compositions including a slightly soluble drug incorporated in a water-swellable, but water-insoluble cross-linked polymer, a surface active agent, and an oil show much improved...
6103710 Glucocorticoid response elements  
The invention features an isolated herpesvirus glucocorticoid response element comprising a DNA sequence comprising two consensus hexanucleotide glucocorticoid receptor binding sequences having at...
6096731 Method for preventing tissue damage associated with graft-versus-host or host-versus-graft disease following transplantation  
A method for preventing tissue damage associated with graft-versus-host disease in a patient having undergone hematopoietic cell transplantation, and host-versus-graft disease in a patient having...
6093389 Methods and compositions for attracting and controlling termites  
The present invention provides a composition for attracting termites containing a steroid derivative of formula I ##STR1## The present invention also provides a method for attracting or controlling...
6083941 Inhibition of NMDA receptor activity by pregnenolone sulfate derivatives  
The present invention relates to a method of inhibiting N-methyl-D-aspartate (NMDA) glutamate receptor-mediated ion channel activity (NMDA receptor activity), comprising contacting a neuronal cell...
6083940 Method and composition for effecting contraception in a mammalian male  
Novel antiandrogenic agents are provided. An exemplary group of compounds has the structural formula (I) ##STR1## wherein R 1 through R 10 , a and b are as defined herein. Pharmaceutical...
6077531 Estradiol and progesterone-based medicament  
A medicament consisting of a biological medium-soluble capsule containing a micronised progesterone suspended in oil is disclosed, characterised in that the capsule also contains estradiol enclosed...
6066627 Steroids as neurochemical initiators of change in human blood levels of LH  
The invention relates to a method of altering the blood levels of LH or FSH in an individual. The method comprises nasally administering a steroid which is a human vomeropherin, such that the...
6063402 Purified galactomannan as an improved pharmaceutical excipient  
Disclosed is a substantially anhydrous, powdered, galactomannan composition consisting essentially of a galactomannan hydrocolloid exhibiting about 50% to about 90% by weight of anhydromannose...
6054447 Progesterone for treating or reducing ischemia  
The present invention provides a method of treating or reducing ischemia or incidence of cardiovascular events by administering progesterone. Progesterone, unlike synthetic progestins, has been...
6046182 Steroid carbamates as potentiating agents  
Novel potentiating steroid carbamates having the general formula (I) ST-OCONR 1 R 2 (I) wherein ST is a steroid or steroid derivative, of the structure (II)...
6028106 Treatment of urinary incontinence with nitric oxide synthase substrates and/or nitric oxide donors alone or in combination with estrogen or progesterone and/or other agents  
The invention provides a method for the treatment and prevention of urinary incontinence in mammals, e.g., human males and females, especially nonpregnant female mammals, by administering a nitric...
6020327 Control of hair growth  
A method for treating hair loss is disclosed by topically adminstering an aromatase inhibitor to a mammal, including humans, on the area to be treated.
6020356 Pharmaceutical composition for the treatment of autoimmune diseases  
A pharmaceutical composition comprising an anti-inflammatory drug capable of suppressing the production of cytokines (CSAID) an immunosuppressant and a pharmaceutically acceptable excipient.
6013642 Use of estrone derivatives as steroid sulphatase inhibitors  
5994333 Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods  
The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human vomeropherin, e.g. a pregnane or cholane steroid, or a...
5980945 Sustained release drug formulations  
A sustained release drug formulation including: a drug; a biodegradable polymer which is insoluble in water; and an oil vehicle in which both the drug and the polymer are dissolved. The oil vehicle...
5981517 Androstene derivatives  
The invention provides new androstene derivatives having anti-inflammatory activity, pharmaceutical compositions containing them, and methods of administering them to warm-blooded animals in the...
5980940 Pharmaceutical combination preparation for hormonal contraception  
The invention provides a pharmaceutical combination preparation with two hormone components in a packaging unit and intended for time-sequential oral administration, comprising a number of daily...
5972922 Steroids which inhibit angiogenesis  
Novel angiostatic Δ 4 ,9(11) -steroids (I), ##STR1## C 21 -oxygenated steroids (II) and other known steroidal compounds have been found to be useful in treating angiogenesis in mammals who have a...
5968918 Method for the prevention of coronary artery spasm  
The present invention relates to the prevention of coronary artery spasm in mammals by the administration of an effective amount of an antiestrogen compound to block estrogen receptors for the...
5968919 Hormone replacement therapy drug formulations for topical application to the skin  
Topical alcoholic or aqueous alcoholic gels containing testosterone, progesterone, estradiol or other hormones have enhanced penetration through skin by including in the formulation...
5965550 Process for the preparation of 4-amino-Δ.sup.4 -3-ketosteroids via 4-nitro-Δ.sup.4 -3-ketosteroids  
The invention discloses 3-ketosteroids of the following formula used to inhibit steroid C 17 -20 lyase: ##STR1## wherein R is OH, C 1 -C 6 alkanoyl, C 1 -C 6 alkanoyloxy, C 1 -C 4 alkanol,...
5965549 Ciprofloxacin-hydrocortisone suspension  
The invention is directed to an aqueous non-ototoxic, topical, otic pharmaceutical composition of matter for treating a mammal consisting essentially of: ciprofloxacin or a pharmaceutically...
5962443 19-nur-pregnane steroids as neurochemical initiators of change in human hypothalamic function  
The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human vomeropherin, e.g. a 19-nor pregnane steroid, or a...
5962442 Irreversible inhibition of human 5α-reductase  
The invention concerns the treatment of hyderandrogenic conditions in humans by the formation of a novel mechanism-based irreversible inhibitor of human 5α-reductase enzymes from...
5955454 Nasal pharmaceutical composition containing a progestogen  
The invention relates to a nasal pharmaceutical preparation suitable for nasal administration containing a progestogen and a methylated β-cyclodextrin having a degree of substitution of between...
5935948 Method of treating and preventing gallstones  
The present invention relates to a method of treating and/or preventing gallstones comprising administering a therapeutically effective amount of dehydrocholic acid. It is based, at least in part,...
5919465 Methods for augmenting immunological responses through the administration of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone-sulfate (DHEA-S)  
Methods for augmenting immune responses in immunodeficient individuals are disclosed. The methods utilize steroid hormones, particularly DHEA, its prohormones (particularly DHEA-S), and...
5914324 6-Hydroxy and 6-oxo-androstane derivatives active on the cardiovascular system and pharmaceutical compositions containing same  
6-hydroxy and 6-oxo-androstane derivatives of formula (I), active on the cardiovascular system. ##STR1## wherein: the symbol A represents CH--OR, CN--OR, CH--CHN--OR and CCH--N--OR; and R...
5906987 Treatment of male climacteric disorders with nitric oxide synthase substrates and/or donors, in combination with androgens and/or aromatase inhibitors  
The symptoms of climacterium in male mammals, e.g., hypertension, cardiovascular disease and osteoporosis, are ameliorated by the administration to an afflicted individual one or both of a nitric...
5888996 Inhibition of NMDA receptor activity and modulation of glutamate-mediated synaptic activity  
The present invention relates to a method of inhibiting N-methyl-D-aspartate (NMDA) glutamate receptor-mediated ion channel activity (NMDA receptor activity), comprising contacting a neuronal cell...
Matches 101 - 150 out of 468 < 1 2 3 4 5 6 7 8 9 10 >