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6670350 |
Method of administering dienogest in high dosages to reduce the body of the breast and pharmaceutical composition for same
A method of administering dienogest to a women in high dosages for reducing the body of the breast is described. The dosage should be at least ten times the effective dosage for inhibiting...
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6656970 |
Method and compositions for solubilization of pentacyclic triterpenes
The present invention provides compositions and methods for the solubilization of poorly soluble drugs such as triterpenes like betulinic acid and/its derivatives in pharmaceutically acceptable...
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6645954 |
Compositions comprising ethisterone or its derivatives
Treatment of androgen deficiency using a pharmaceutically effective dose of ethisterone or an ethisterone derivative such as Danazol. In particular, androgen deficiency in the aging male, also...
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6645953 |
Meiosis regulating compounds
Sterol derivative compounds, structurally related to natural compounds which can be extracted from bull testes and from human follicular fluid, useful for regulating meiosis in oocytes and in male...
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6641800 |
Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane
Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer...
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6642219 |
Progestogen-antiprogestogen regimens
An estrogen-free contraceptive is provided which does not have the bleeding-related drawbacks of conventional progestogen-only pills. Thus the invention is a contraceptive kit comprising a combined...
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6620590 |
Diagnosis of pre-eclampsia
A method for diagnosis of pre-eclampsia is disclosed, which comprises measuring the hormone inhibin A in a biological sample such as maternal serum. The method allows non-invasive, early diagnosis...
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6610674 |
Method of treating inflammatory conditions with progesterone analogs
The present invention provides methods for treating inflammatory conditions, including but not limited to, inflammatory bowel disease (ulcerative colitis, Crohn's disease, and proctitis), other...
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6605605 |
Estrogenic substances combined with cruciferous indole compounds
Provided herein are medicinal compositions of matter that comprise an estrogenic medication component and a cruciferous indole component (indole 3-carbinol, diindolylmethane, or any derivative...
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6602487 |
Methods and tests for producing and for inhibiting coronary artery vasospasms
Methods for producing coronary vasospasms and for inhibiting coronary vasospasms are disclosed. Both in vivo and in vitro methods are disclosed. The methods are useful as tests for determining the...
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6593316 |
Use of &Dgr 5-androstene-3βol-7,17-dione in the treatment of lupus erythematosus
Lupus erythematosus can be treated by administering therapeutic amounts of Δ5-androstene-3β-ol-7,17-dione and metabolizable precursors thereof, such as Δ5-androstene-3β-acetoxy-7,17-dione,...
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6593317 |
Progestin therapy for maintaining amenorrhea
The present invention teaches that daily, cyclical vaginal delivery of progestin may be used to provide regular, predictable withdrawal bleeding during hormone replacement therapy. The present...
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6583129 |
Administration of non-oral androgenic steroids to women
The present invention provides compositions, methods, and kits for improving health in a woman having elevated SHBG levels, or who is receiving oral estrogen supplementation, by non-orally...
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6579864 |
3-methylene steroid derivatives
The invention concerns a 3-methylene steroid derivative having general formula (1) wherein R 1 is H or together with R 3 forms a β-epoxide or R 1 is absent if there is a 5-10 or 4-5 double...
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6562790 |
Hormone therapy methods and hormone products for abating coronary artery blockage
Methods for abating coronary artery blockage in human subjects include administering a combination of natural hormones including human growth hormone with sufficient T3 thyroid supplement to...
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6552010 |
Treatment of SLE with dehydroepiandrosterone
This invention provides a method of treating systemic lupus erythematosus (SLE) with (DHEA) and a related pharmaceutical product.
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6544971 |
Method of increasing alertness by administration of a vomeropherin, and vomeropherin-emitting alarm devices
A method of increasing alertness in an individual by administering an effective amount of an alertness-increasing vomeropherin to the individual; and an alarm device that, when activated, emits an...
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6531462 |
Medicament for treating obesity and improving lipid metabolism
A medicament for preventive and therapeutic treatment of obesity and a disease with abnormal lipid metabolism which comprises a 24-alkylcholest-5-en-3-one as an active ingredient.
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6528501 |
22s-hydroxycholesta-8, 14-diene derivatives with meiosis regulating activity
The invention relates to 22S hydroxycholesta-8, 14-diene derivatives having general formula (I) wherein R 1 is OR, OSO 3 H or —NOR; with R being H, (C 1-6 )alkyl or (C 1-6 )acyl; each of R 2 ...
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6514980 |
Nucleoside analogs in combination therapy of herpes simplex infections
A pharmaceutical product comprising a nucleoside analogue active against herpes simplex virus, such as acyclovir/valaciclovir or penciclorivir/famciclovir, and an immunosuppressant, as a combined...
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6514956 |
Steroids, their preparation, pharmaceutical compositions thereof and uses of the compounds
The present invention concerns with steroid compounds of formula (I) wherein R 1 is cyclohexyl or cycloheptyl, R 2 is hydrogen or C 1 -C 6 alkyl, R 3 is hydrogen, C 1 -C 6 alkyl or...
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6514958 |
Stabilized tibolone compositions
A stabilized pharmaceutical dosage unit comprising tibolone, in an amount of from 0.1% to 10% by weight of the dosage unit, and a pharmaceutically acceptable carrier. The dosage unit is contained...
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6514957 |
Method of alleviating the violence and stimulating the appetite of stag in the puberty age of the fall and method of promoting the growth of stag's horn
A method of alleviating the violence and stimulating the appetite of stags in the puberty age of the fall and a method of allowing to cut and collect more than twice stag's horn is provided by...
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6511969 |
Method for reducing coronary artery reactivity
A method for reducing coronary artery reactivity. A predetermined amount of natural progesterone is provided by a convenient and pleasant delivery system to the blood stream, sufficient to reduce...
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6503894 |
Pharmaceutical composition and method for treating hypogonadism
A pharmaceutical composition useful for treating hypogonadism is disclosed. The composition comprises an androgenic or anabolic steroid, a C1-C4 alcohol, a penetration enhancer such as isopropyl...
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6500815 |
Substituted 11.beta steroid derivatives, method for preparing same and intermediates of said method, use as medicine and compositions containing them
The invention concerns compounds of formula (I) wherein: X, Y, R 1 , R 2 , Z, G are as defined in the description, the methods for preparing them and the intermediates in said method, their use as...
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6489313 |
Memory by the administration of &Dgr 5-androstene-3β-ol-7,17-dione and 3β esters
The memory of a healthy mammal and the memory of a mammal with age impaired memory can be improved by administering an effective amount of Δ5-Androstene-3β-ol-7,17-dione and 3β esters thereof.
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6486146 |
Cancer accelerants and phase synchronization methods
The invention discloses compositions and methods for increasing chemotherapeutic specificity to endocrine dependent cancers, and reducing systemic toxicity, through administration of endocrine...
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6465446 |
Treatment of dermatitis by the topical application of &Dgr 5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof
Dermatitis can be treated by the administration of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof, such as Δ5-androstene-3β-acetoxy-7,17 dione, to the skin.
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6461591 |
Medical aerosol formulations
A pressure-liquefied propellant mixture for aerosols, comprising a fluorinated alkane, in particular 1,1,1,2-tetrafluoroethane and/or 1,1,1,2,3,3,3-heptafluoropropane, and carbon dioxide, makes...
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6440954 |
Inhibition of vascular smooth muscle cell proliferation
Methods of treating a mammal having a condition characterized by vascular smooth muscle cell proliferation, where the mammal is treated with progesterone or an agonist thereof. Also disclosed are...
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6432938 |
19-nor-cholane steroids as neurochemical initators of change in human hypothalamic function
The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human vomeropherin, e.g. a 19-nor cholane steroid, or a...
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6423698 |
Combination therapy for the prophylaxis and/or treatment of benign prostatic hyperplasia
A combination therapy for the prophylaxis and/or treatment of benign prostatic hyperplasia in susceptible warm-blooded animals which comprises administering a combination of two or more compounds...
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6413951 |
20-fluoro-17(20)-vinyl steroids
The invention relates to 20ξ-fluoropregna-4,17(20)-dien-3-on-21-oic acid ethyl ester, 20ξ-fluoro-3β-hydroxypregna-5,17(20)-dien-21-oic acid ethyl ester, 20ξ-fluoro-21-hydroxypregna-4,17...
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6399084 |
Method for diminishing wrinkles and fine lines of the skin by the topical application of &Dgr 5-androstene-3β-ol-7, 17 dione and metabolizable precursors thereof
Wrinkles and fine lines occurring on human skin can be diminished by the administration of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof, such as...
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6399085 |
Method of moisturizing the skin by the topical application of &Dgr 5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof
Human skin can be moisturized by the administration of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof, such as Δ5-androstene-3β-acetoxy-7,17 dione.
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6395721 |
Low potency unpreserved sterile topical corticosteroid compositions for dermatitis
Low potency, preservative free sterile topical anti-inflammatory steroid compositions are to be applied to the area surrounding the eye. The compositions involve, for example, sterile gauze pads in...
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6391868 |
Use of 5-alpha-androst-1-en-3,17-dione to increase the level of the anabolic/androgenic hormone 17-beta-hydroxy-5-alpha-androst-1-en-3-one in humans
This invention involves the administration of the natural androgen metabolite 5-alpha-androst-1-en-3,17-dione(1-androstenedione) to produce an androgenic and anabolic response in humans....
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6372732 |
Use of delta5-androstene-3beta-ol-7, 17-dione in the treatment of lupus erythematosus
Lupus erythematosus can be treated by administering therapeutic amounts of delta-5-androstene-3-beta-ol-7,17-dione and its metabolizable precursors, which are not appreciably metabolized in vivo to...
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6369115 |
Stabilized powder formulations
A dry powder formulation for treatment of pulmonary conditions, via inhalation, includes an effective amount of formoterol or a salt or solvate thereof, in a dry powder form, an effective amount of...
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6352980 |
Estrenes for inducting hypothalamic effects
The invention relates to estrene steroids, which bind to neuroepithelial receptors. The steroid is preferably administered in the form of a pharmaceutical composition containing one or more...
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6331534 |
Steroids as neurochemical stimulators of the VNO to alleviate pain
The invention relates to a method of alleviating pain. The method comprises nasally administering a steroid which is a human vomeropherin, such that the vomeropherin binds to a specific...
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6319901 |
Methods for prolonging cell membrane permeability
Methods for improving the efficiency of electroporation protocols as well as methods to enhance the permeabilized state, in order to improve the intracellular delivery of therapeutic substances,...
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6316431 |
Use of an aromatase inhibitor in the treatment of decreased androgen to estrogen ratio and detrusor urethral sphincter dyssynergia in men and method to study the dyssynergia in male rodents
This invention relates to the use of an aromatase inhibitor in the treatment of decreased androgen to estrogen ration (DATER) as well as to a method for the treatment of detrusor urethral sphincter...
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6297228 |
Use of angiostatic steroids in photodynamic therapy
Methods for treating ocular neovascularization using photodynamic therapy in combination with an angiostatic steriod are disclosed.
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6277829 |
Process for preparing of aqueous formulation for opthalmic use
The present invention describes a process for the preparation of aqueous formulations containing azithromycin for ophthalmic use, as well any formulations obtained by this process and their topical...
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6274572 |
Pregnane derivatives with no alpha-17 substitutent, their medicinal use, manufacturing method and its intermediaries and related compounds
The subject of the invention is the products of formula (I): ##STR1## in which either R 1 represents halogen, hydroxyl, (C 1 -C 8 ) alkyloxy or (C 1 -C 12 ) acyloxy, and R 2 represents halogen...
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6271220 |
Anti-angiogenic agents
The application discloses methods of treating mammalian diseases characterized by undesirable angiogenesis by administering compounds including those having the general formulae ##STR1## wherein A...
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6245757 |
Use of progestins to treat ischemic event
A method for the treatment of ischemic damage, such as damage due to stroke or myocardial infarction, is provided, comprising administering to a mammal afflicted with stroke, an effective amount of...
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6242436 |
Use of 5alpha-androstanediol or 5alpha-androstanedione to increase dihydrotestosterone levels in humans
This invention discloses a method of administering direct precursors of the hormone dihydrotestosterone as a means of increasing androgen levels in humans. As men age, a decline in androgenic...
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