|
Match
|
Document |
Document Title |
|
|
7615546 |
Topical delivery system for phytosterols
This invention relates to certain sugar esters of phytosterols of formula (I). These esters are useful for topical application, and for the treatment of skin condition, including age spots, acne,...
|
|
|
7601706 |
Bile-acid conjugates providing for sustained systemic concentration of drugs
This invention is directed to compounds that provide for sustained systemic concentrations of therapeutic or prophylactic agents following administration to animals. This invention is also directed...
|
|
|
7592329 |
Crystalline complexes of fluticasone-2-furoate
There is provided a crystalline complex comprising a compound of formula (I)
in which the crystal lattice is stabilized by the presence of a guest molecule, characterized in that the...
|
|
|
7576055 |
Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier
This invention relates to a highly efficient artificial low-density lipoprotein (LDL) carrier system for the targeted delivery therapeutic agents across the blood-brain barrier (BBB). In...
|
|
|
7563565 |
Method of preparing bio-identical hormones
The embodied composition is a dose of bio-identical hormones in a solvent with a vasodilator, a hormone modulator, and a carrier for balancing and maintaining Cortisol level in a human. The dose...
|
|
|
7544674 |
Topical skin care composition
A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide...
|
|
|
7541350 |
Formulation containing anti-inflammatory androstane derivative
There is provided a pharmaceutical formulation comprising an aqueous suspension of particulate compound of formula (I)
or a solvate thereof.
|
|
|
7531528 |
Formulation containing anti-inflammatory androstane derivatives
There is provided according to the invention a pharmaceutical formulation comprising an aqueous carrier liquid having dissolved therein (a) an ester of fluticasone or a solvate thereof as...
|
|
|
7507720 |
5-Beta-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia
The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical compositions are also disclosed.
|
|
|
7498321 |
17β-carbothioate 17α-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents
There are provided according to the invention compounds of formula (I) wherein R 1 represents C 1-6 alkyl or C 1-6 haloalkyl; R 2 represents —C(═O)-aryl or —C(═O)-heteroaryl; R 3 ...
|
|
|
7488722 |
Anxiolytic Marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods
Pharmaceutical compositions for preventing or treating anxiety, comprising betulinic acid or derivatives thereof are provided. Methods for preventing or treating anxiety with betulinic acid or...
|
|
|
7405206 |
Anti-inflammatory androstane derivatives
There are provided compounds of formula (I)
wherein
R 1 represents O, S or NH; R 2 represents —C(═O)-aryl or —C(═O)-heteroaryl; R 3 represents hydrogen, methyl (which may be in...
|
|
|
7335349 |
Fish attractants
The present invention provides a fish attracting composition. Previously fish sex hormones were considered only to have a role in sexual reproduction, however the present invention shows that these...
|
|
|
7312207 |
Topical steroid cream formulations
Disclosed is a novel mometasone furoate cream formulation for topical administration in a oleaginous base containing propylene glycol. This cream is a cosmetically elegant preparation of mometasone...
|
|
|
7112580 |
3-nitrogen-6, 7-dioxygen steroids and uses related thereto
A compound of the formula:
and pharmaceutically acceptable salts, solvates, stereoisomers and prodrugs thereof, in isolation or in mixture, wherein R groups are as defined by the present...
|
|
|
7108867 |
Process for preparing particles
A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator...
|
|
|
7101866 |
Anti-inflammatory androstane derivative
According to one aspect of the invention, there is provided a compound of formula (I)
and solvates thereof. There are also provided compositions containing the compound, processes for...
|
|
|
7087590 |
19-norbufalin derivatives, their preparation and pharmaceutical compositions containing them
A 19-norbufalin derivative compound of formula (I):
wherein the R groups are as defined by the present specification. The compounds are Na + K − -ATPase inhibitors and can be used in the...
|
|
|
7053076 |
Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
Disclosed are compounds that exhibit high transport across the intestinal wall of an animal. The compounds may optionally be linked to drugs that are poorly absorbed or poorly transported across...
|
|
|
7049305 |
Bile-acid conjugates providing for sustained systemic concentration of drugs
This invention is directed to compounds that provide for sustained systemic concentrations of therapeutic or prophylactic agents following administration to animals. This invention is also directed...
|
|
|
7037548 |
Soybean embryo fat/oil and process for producing soybean material with high embryo concentration
The purpose of the present invention is to extract oil from the soybean material containing soybean germ as a main component, and to utilize it. The present invention relates to a method for...
|
|
|
7015210 |
Methods of treating ophthalmic disorders with epoxy-steroidal aldosterone receptor antagonists
A method for treating or preventing ophthalmic disorders comprising the administration of one or more aldosterone receptor antagonists that contain a 9,11-epoxy moiety, such as eplerenone is...
|
|
|
6956030 |
Use of mometasone furoate for treating upper airway diseases
The administration of aerosolize particles of mometasone furoate in the form of dry powders, solutions, or aqueous suspension for treating corticosteroid-responsive diseases of the surfaces of...
|
|
|
6953785 |
Estra-1,3,5(10)-triene derivatives
Provided is steroid sulfatase inhibitors comprising, as the active ingredient, an estra-1,3,5(10)-triene derivative which is represented by formula (I):
{wherein R 1 and R 2 are the same or...
|
|
|
6949532 |
Use of mometasone furoate for treating airway passage and lung diseases
The administration of aerosolize particles of mometasone furoate in the form of dry powders, solutions, or aqueous suspension for treating corticosteroid-responsive diseases of the surfaces of...
|
|
|
6930125 |
Airway alkalinization as a therapy for airway diseases
The present invention relates to a method of treating asthma by raising the pH of the airways of an individual. The effect can be mediated directly by administering a pharmaceutically acceptable...
|
|
|
6921757 |
Organic compounds
Compounds of formula (I), where R is a monovalent cyclic organic group having from 3 to 15 atoms in the ring system, useful as pharmaceuticals
|
|
|
6887861 |
Compounds for intracellular delivery of therapeutic moieties to nerve cells
A method for improving intracellular administration of a therapeutic agent is provided comprising: contacting cells with a compound comprising a charged derivative of a therapeutic agent having a...
|
|
|
6878699 |
Taccalonolide microtubule stabilizing agents
In accordance with the present invention, there have been identified extracts from a tropical plant that initiate paclitaxel-like microtubule bundling. Bioassay-directed purification yields the...
|
|
|
6875758 |
Method of treating hyperlipidemic and hyperglycemic conditions in mammals using pregnadienols and pregnadienones
The invention provides a method of using pregnadienones and pregnadienols represented by the structural formula (I) as shown herein below
Wherein X═OH or O or combination thereof and...
|
|
|
6803030 |
Bile acids conjugates with metal ion chelates and the use thereof
Compounds able to chelate paramagnetic metal ions and the use thereof as contrast agents in the technique known as “Magnetic Resonance Imaging” (M.R.I.).
|
|
|
6780855 |
11β-HALOGEN-7α-SUBSTITUTED ESTRATRIENES, PROCESS FOR THE PRODUCTION OF PHARMACEUTICAL PREPARATIONS THAT CONTAIN THESE 11β-HALOGEN-7α-SUBSTITUTED ESTRATRIENES AS WELL AS THEIR USE FOR THE PRODUCTION OF PHARMACEUTICAL AGENTS
This invention describes the new 11β-halogen-7α-substituted estratrienes of general formula I in which R 11 is a fluorine or chlorine atom, and the other substituents have the meanings that...
|
|
|
6777200 |
Kinesin motor modulators derived from the marine sponge Adocia
This invention provides novel compounds derived from a marine sponge, Adocia sp., that specifically modulat kinesin activity by targeting the kinesin motor domain and mimicking the activity a...
|
|
|
6767901 |
Ciclesonide contained pharmaceutical composition for application to mucosa
The present invention provides a pharmaceutical composition for application to the mucosa to be used in drug therapy comprising a water-insoluble and/or water-low soluble substance, ciclesonide,...
|
|
|
6759399 |
Use of antimineralocorticoid compounds against narcotic withdrawal syndrome
The method of treating narcotic withdrawal symptoms in warm-blooded animals comprising administering to warm-blooded animals in need thereof an amount of a compound having anti-mineralocorticoid...
|
|
|
6759398 |
Anti-inflammatory androstane derivative
According to one aspect of the invention, there is provided a pharmaceutical formulation for administration by inhalation comprising a compound of formula (I), or a solvate thereof, together...
|
|
|
6743414 |
Inhalation administration of biophosphonates
The present invention relates to the treatment and prevention of bone diseases in humans, including osteoporosis in postmenopausal women, Paget's Disease and hypercalcemia, by administration of a...
|
|
|
6716437 |
Topical composition and method for enhancing lipid barrier synthesis
The present invention relates to topical compositions useful in enhancing lipid synthesis in skin comprising an effective amount of cafestol or kahweol, or derivative thereof, in combination with a...
|
|
|
6696432 |
Combination of dehydroepiandrosterone and aromatase inhibitors and use of this combination to produce a medicament for treating relative and absolute androgen deficiency in men
The present invention concerns the combination of dehydroepiandrosterone (DHEA) and at least one aromatase inhibitor and the use of such a combination to produce a medicament for treating relative...
|
|
|
6680310 |
Methods for preventing antipsychotic-induced weight gain
This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents capable of inhibiting the binding of cortisol to its receptors can...
|
|
|
6641800 |
Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane
Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer...
|
|
|
6583129 |
Administration of non-oral androgenic steroids to women
The present invention provides compositions, methods, and kits for improving health in a woman having elevated SHBG levels, or who is receiving oral estrogen supplementation, by non-orally...
|
|
|
6531461 |
Medicament for the treatment of diabetes
A series of compounds of general structure I and metal salts thereof. These compounds are useful in the treatment of diabetes mellitus and associated conditions when administered in an effective...
|
|
|
6500815 |
Substituted 11.beta steroid derivatives, method for preparing same and intermediates of said method, use as medicine and compositions containing them
The invention concerns compounds of formula (I) wherein: X, Y, R 1 , R 2 , Z, G are as defined in the description, the methods for preparing them and the intermediates in said method, their use as...
|
|
|
6488937 |
Allergy treatment method using a rapid immunotherapy protocol
A method of treating a patient sensitive to an allergen includes a desensitizing rapid immunotherapy protocol of administering to the patient a series of gradually increasing doses of a composition...
|
|
|
6468994 |
Budesonide particles and pharmaceutical compositions containing them
The invention provides finely divided, substantially crystalline particles of budesonide characterized in that they are substantially smooth and having a BET value of from 1 to 4.5 m2/g, a process...
|
|
|
6342490 |
Pharmaceutical composition containing uscharidin or its analogues
The invention provides compositions comprising uscharin and the use of uscharin to combat cell proliferation for example in the treatment of cancer. Administration of uscharin may kill or reduce...
|
|
|
6306845 |
Method for treating demyelinating disease
The present invention provides a method for treating a demyelinating disease in a subject which includes administering to the subject a therapeutically effective amount of a high affinity...
|
|
|
6297227 |
Methods and compositions for treating sinusitis, otitis media and other related disorders using antihistamines
The present invention discloses antibiotic-excluded compositions and methods to treat non-infective sinusitis and otitis media. The compositions comprise a therapeutically effective amount of a...
|
|
|
6288041 |
Sialic acid derivatives
Sialic acid derivatives represented by the following general formula: ##STR1## wherein R 1 represents a residue of a steroid compound excluding cholestane and cholestene residues, R 2 represents...
|