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7619110 |
Amino acid derived prodrugs of propofol, compositions, uses and crystalline forms thereof
The present invention provides a prodrug of propofol and crystalline forms thereof, methods of making the propofol prodrug and crystalline forms thereof, pharmaceutical compositions of the propofol...
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7618956 |
Reduction of hair growth
Mammalian hair growth is reduced by applying an agonist of farnesoid X receptor.
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7615545 |
Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology
This invention relates to a method of preventing pregnancy and treating PMS including PMDD. More particularly, the invention relates to a method, which involves administering one of several...
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7601707 |
Method for instantly relieving tissue inflammation
A method for treating an inflamed tissue includes locally applying a solution comprising a corticosteroid and an anesthetic agent to the inflamed tissue so that the solution directly contacts the...
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7582670 |
Methods of treating an inflammatory-related disease
The invention relates to pharmaceutical compositions and methods of treating inflammatory-related diseases associated with pro-inflammatory cytokine expression and/or reduced expression of...
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7576073 |
Combined therapy for the treatment of parkinson's disease
The present invention concerns a method and a pharmaceutical composition for treating the symptoms associated to Parkinson's disease. The method and the pharmaceutical composition use a combination...
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7572779 |
Oral pharmaceutical products containing 17β-estradiol-3-lower alkanoate, method of administering the same and process of preparation
A pharmaceutical dosage unit for oral administration to a human female comprising a therapeutically effective amount of 17β-estradiol-3-lower alkanoate, most preferably 17β-estradiol-3-acetate,...
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7566803 |
Vitamin D receptor modulators
The present invention relates to novel, non-secosteroidal, diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1α,25 dihydroxy vitamin D3. These...
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7563565 |
Method of preparing bio-identical hormones
The embodied composition is a dose of bio-identical hormones in a solvent with a vasodilator, a hormone modulator, and a carrier for balancing and maintaining Cortisol level in a human. The dose...
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7560448 |
Enhancement of activity and/or duration of action of soft anti-inflammatory steroids for topical or other local application
Methods and compositions for enhancing the activity and/or duration of action of loteprednol etabonate and other soft anti-inflammatory steroids of the haloalkyl...
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7553877 |
Modulators of the glucocorticoid receptor
The present invention provides compounds of the formula
wherein A is of the formula
and X, Y, n, R 1 —R 25 are as described in the specification which are modulators of the...
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7553829 |
Treatment of chronic fatigue syndrome and fibromyalgia syndrome
Chronic fatigue syndrome (CFS) and fibromyalgia syndrome (FMS) can be treated by the administration of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof.
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7547673 |
Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production
The present invention relates to methods of treating a cancerous tumor using selective inhibitors of ATP production. The present invention also relates to pharmaceutical preparations comprising...
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7544673 |
Coating compositions for bioactive agents
A coating composition and related method for use in applying a bioactive agent to a surface in a manner that will permit the bioactive agent to be released from the coating in vivo. The composition...
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7514472 |
Fat or oil composition
Described is a fat or oil composition which comprises at least 35 wt % of a diacylglycerol, the constituent fatty acids of said diacylglycerol satisfying the following equation: (an amount of a...
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7498334 |
Pyrrolopyrimidines as phosphodiesterase VII inhibitors
Pyrrolopyrimidine derivatives of the formula I
in which R 3 , R 4 , R 5 , R 6 and X are as defined in claim 1 , act as phosphodiesterase VII inhibitors and can be employed for the treatment...
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7498303 |
GNRH analogues for treatment of urinary incontinence
The use of at least one GnRH analogue for the preparation of a medicament for the prevention and/or treatment of side effects of ovarectomy or symptoms associated with reproductive senescence in...
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7494984 |
Substituted imidazo[1,2-a]pyrimidines as HIV viral DNA integrase inhibitors
The invention encompasses a series of bicyclic heterocyclic compounds of Formula I which are inhibitors of HIV integrase and prevent viral integration into human DNA. This action makes the...
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7488734 |
Methods of treating hormone-related conditions using thio-oxindole derivatives
The present invention provides methods of inducing contraception which includes delivering to a female a composition containing a compound of formula I, or tautomers thereof, in a regimen which...
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7488723 |
Use of non-feminizing estrogens as treatment for retinal vascular diseases
The invention provides pharmaceutical compositions containing non-feminizing estrogen and methods of using these compositions to prevent or ameliorate retinal vascular diseases.
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7462646 |
Osteoclastogenesis inhibitors and uses thereof
The present invention provides a method of reducing or inhibiting osteoclast development induced by the receptor for activation of nuclear factor kappa B ligand (RANKL), comprising the step of...
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7459445 |
Estrogenic compounds and topical pharmaceutical formulations of the same
Novel estrogenic compounds of Formula I are provided.
wherein the bond represented by the wavy line may be a single or double bond such that when the wavy line is a single bond, R 1 is...
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7456159 |
Enhanced drug delivery in transdermal systems
A composition for transdermal administration resulting from an admixture includes: a therapeutically effective amount of a drug that includes a parent drug and a prodrug; and and a pharmaceutically...
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7449453 |
Compositions of ezetimibe and methods for the treatment of cholesterol-associated benign and malignant tumors
A method of prevention or treatment of a cholesterol-associated tumor is provided which comprises administering a therapeutically effective amount of an azetidinone-based cholesterol absorption...
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7442837 |
Phenethanolamine derivatives for treatment of respiratory diseases
The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their...
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7429576 |
Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
Novel methods for the medical treatment and/or inhibition of the development of osteoporosis, breast cancer, hypercholesterolemia, hyperlipidemia or atherosclerosis in susceptible warm-blooded...
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7427609 |
Treatment of conditions relating to hormone deficiencies by administration of progestins
The present invention includes methods for preventing endometrial hyperplasia associated with estrogen therapy through the administration of a progestin agent. The methods presented may include...
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7414021 |
Method and composition for restoration of age related tissue loss in the face or selected areas of the body
A treatment method for restoring of age related tissue loss in the face or selected areas of the body is disclosed which includes injecting an injectable composition containing a growth factor and...
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7399784 |
Tocopherol and tocotrienol anti-obesity medicaments
Anti-obesity compositions include medicaments comprising predetermined amounts of a phytyl substituted chromanol and an obesity-promoting drug, wherein: said medicament is in unit dosage form...
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7384926 |
Use of non-feminizing estrogens as retinoprotective agents for the treatment of glaucoma
The invention provides pharmaceutical compositions containing non-feminizing estrogen and methods of using these compositions to prevent or ameliorate retinal and optic nerve damage associated with...
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7378107 |
Serum remnant-like lipoprotein concentration regulator
The present invention discloses serum remnant-like lipoprotein concentration regulators containing triglyceride of medium-chain fatty acids, wherein 90% or more by weight of the fatty acids as...
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7364754 |
Ceramic based nanoparticles for entrapping therapeutic agents for photodynamic therapy and method of using same
The present invention provides methods and compositions for photodynamic therapy. The composition comprises ceramic nanoparticles in which a photosensitive drug/dye is entrapped. The ceramic...
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7354913 |
High storage stability inhalable compositions
Inhalable pharmaceutical compositions are provided, for use in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD). These compositions...
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7354608 |
Bio-identical hormones and method of use
The embodied composition is an evening dose of bio-identical hormones in a solvent with a vasodilator, a hormone modulator, and a carrier for balancing and maintaining Cortisol level in a human....
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7351699 |
Use of DHEA or precursors or metabolic derivatives thereof as a depigmenting agent
The use of DHEA or at least one of its biological precursors or of its metabolic derivatives in or for the manufacture of a composition for topical application to the skin, as a pigmentation...
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7335371 |
Combinations for the treatment of inflammatory disorders
The invention features methods and compositions for the treatment of immunonflammatory disorders.
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7335349 |
Fish attractants
The present invention provides a fish attracting composition. Previously fish sex hormones were considered only to have a role in sexual reproduction, however the present invention shows that these...
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7326690 |
Modulation of cell fates and activities by phthalazinediones
Phthalazinediones that function as intracellular redox modulators are useful in treating cells in various disease states where intracellular redox status is impaired. By buffering aberrant redox...
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7320969 |
Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology
This invention relates to a method of preventing pregnancy and treating PMS including PMDD. More particularly, the invention relates to a method, which involves administering one of several...
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7316810 |
Foaming composition for washing and treating hair and/or scalp based on an active principle
The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterized in that it contains in an aqueous medium: at least an active principle selected...
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7297688 |
Starter kit for low dose oral contraceptives
The present invention provides a contraceptive kit which helps to overcome or ameliorate the problem of breakthrough bleeding and spotting associated with lowest dose (15-20 ug EE) estrogen...
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7291608 |
Anti-inflammatory 17.β.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.α
There are provided compounds of formula (I)
wherein the variables are as defined by the present specification; and solvates thereof, processes for preparing them and their use in therapy.
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7285544 |
Use of nitroxides in treating skin disease
Methods of treating inflammatory skin diseases such as rosacea, atopic dermatitis, contact dermatitis, drug eruptions, psoriasis, seborrheic dermatitis, connective tissue diseases, autoimmune...
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7267813 |
Inhalation particles incorporating a combination of two or more active ingredients
Crystalline spherical inhalation particles incorporating a combination of two or more different active ingredients and a process for the preparation thereof. The particles have a narrow particle...
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7256185 |
Control of selective estrogen receptor modulators
The treatment of an estrogen sensitive condition by the administration of a selective estrogen receptor modulator is improved by additionally administering a progestationally active compound to the...
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7253155 |
Combinations for the treatment of immunoinflammatory disorders
The invention features a method for treating a patient having an immunoinflammatory disorder, by administering to the patient (i) a tetra-substituted pyrimidopyrimidine, and (ii) a corticosteroid...
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7229980 |
Paroxetine cholate or cholic acid derivative salts, and composition comprising paroxetine and cholic acid or derivative thereof
Disclosed herein is a paroxetine cholate or cholic acid derivative salt and a composition comprising paroxetine and cholic acid or a derivative thereof. Further disclosed is a pharmaceutical...
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7223387 |
Antiviral formulations comprising propylene glycol and an isopropyl alkanoic acid ester
A topical composition comprising an antiinflammatory glucocorticoid and a nucleoside analogue antiviral agent in a pharmaceutical carrier characterized in that the carrier comprises about 15 to...
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7220739 |
Therapeutic application of pro-apoptotic benzodiazepines
Benzodiazepine compounds, and methods for using those compounds are provided. Some of the benzodiazepine compounds include 1,4-benzodiazepine-2-one and 1,4-benzodiazepine-2,5-dione compounds of the...
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7217422 |
Compositions and methods for enhancing corticosteroid delivery
The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and...
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