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4898856 Method for treating central nervous system diseases  
A method of treating humans suffering from central nervous system diseases, such as Alzheimer's disease, Parkinson's disease, senile dimentia. The treatment consists of inducing into the patient's...
4898857 Treating control nervous system diseases  
A method of treating humans suffering from central nervous system diseases, such as Alzheimer's disease, Parkinson's disease, senile dementia. The treatment consists of inducing into the patient's...
4897389 Treating central nervous system diseases  
A method of treating human suffering from central nervous system diseases, such as Alzheimer's disease, Parkinson's disease, senile dementia. The treatment consists of inducing into the patient's...
4895715 Method of treating gynecomastia  
A method of treating gynecomastia in noncastrated patients being treated with an antiandrogen for androgen-dependent diseases such as benign prostatic hypertrophy, who are in need of such treating...
4889847 Prevention of glucocorticoid-induced skin atrophy  
The present invention is directed to the topical administration of a retinoid-containing pharmaceutical composition for the prevention of glucocorticoid-induced skin atrophy.
4888331 Coadministration of antigestagen and antiestrogen for gynecological disorders, abortion and labor induction  
An agent containing at least one compound having antiprogestational activity and at least one compound having anti-estrogenic activity is disclosed. The agent is suitable for the induction of...
4883660 Gel bases for pharmaceutical compositions  
Gel bases for pharmaceutical compositions comprise from about 0.5 to about 10.0% by weight ethoxylated (2 to 30 moles of ethoxylation) behenyl alcohol and from about 90 to 99.5% of a glycol solvent...
4882359 Azacycloalkane derivatives, absorption promoters containing the derivatives as the effective ingredient and external preparations containing the absorption promoters  
An azacycloalkane derivative useful for promoting the absorption of a medicine, an absorption promoting agent comprising at least one of the azacycloalkane derivatives as the effective ingredient...
4879287 Pharmaceutical composition  
Pharmacuetical compositions for topical application to the skin are disclosed comprising the hydrated crystalline calcium salt of mupirocin and a corticosteriod intimately mixed therewith. The...
4870067 Oxytocins and antigestagens in combination for induction of birth  
A combination product contains oxytocin and/or an oxytocin analog and an antigestagen for induction of birth.
4866049 Ophthalmic compositionn and method of using same  
The present invention relates to ophthalmic compositions and their preparation and use. More specifically, the invention relates to ophthalmic compositions useful in the treatment of surface...
4861783 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases  
Phenylquinolinecarboxylic acids and derivatives thereof, such as 2-(2'-Fluoro-1,1'-biphenyl-4-yl)-6-fluoro-3-methyl-4-quinoli necarboxylic acid, or a sodium or potassium salt thereof, are useful...
4855305 Compositions and methods of effecting contraception utilizing melatonin  
A method of effecting contraception in human females comprises administering an ovulation-inhibiting amount of melatonin. Optionally, the melatonin is administered in combination with a progestogen...
4855289 Combination of two active substances  
The invention concerns the use of a compound with diuretic properties and of a magnesium supplementation in the form of magnesium monoaspartate hydrochloride, magnesium oxide, magnesium hydroxide...
4804541 Transdermal administration using benzyl alcohol  
A method, composition, and article for use in transdermal or percutaneous administration to humans of systemically active medicaments in the form of a solution in benzyl alcohol.
4797402 Cooling anti-itch skin preparations  
Cooling, anti-itch skin preparations in a hydrophilic base, comprising an anti-inflammatory corticosteroid, peppermint oil and urea.
4791099 Method of treatment for central nervous system diseases such as Alzheimer's 's disease  
A method of treating humans suffering from central nervous system diseases, such as Alzheimer's disease, cerebral atrophy, Parkinson's disease, senile tremor, essential tremor, and cerebellar...
4775529 Steroid lotion  
An improved lotion formulation for the topical administration of corticosteroids in a hydro-alcoholic base containing propylene glycol.
4771042 Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments  
A method of inhibiting angiogenesis in a warm blooded animal which comprises administering to said animal an anti-angiogenic effective amount of a compound of the formula: ##STR1## wherein the...
4756907 Active/passive immunization of the internal female reproductive organs  
Antibody or antigen containing microparticles for the active or passive immunization of the internal female reproductive organs, comprising: microparticles of an antigen or antibody incorporated in...
4757056 Method for tumor regression in rats, mice and hamsters using hexuronyl hexosaminoglycan-containing compositions  
Regression of established malignant tumors in rats, mice and hamsters is achieved with a combination of the heparin fragment hexuronyl hexosaminoglycan sulfate (HHS) together with a steroid such as...
4732892 L-α-amino acids as transdermal penetration enhancers  
The disclosed invention provides methods and compositions ulilizing L-α-amino acids for enhancing the rate of penetration through the skin of both topical medicaments and of drugs employed for...
4720489 Hair growth modification with ornithine decarboxylase inhibitors  
The rate and character of human hair growth including androgen-stimulated beard hair growth in intact, sexually mature males is altered by the topical application out of a dermatologically...
4686103 Method of managing cattle breeding herds  
Cattle breeding herds are managed for accelerated time-controlled calving, using groups of cows predicted to calve within a period of 10 days, 1000 to 10,000 units of purified porcine relaxin are...
4684635 Compositions and methods for inhibiting the action of androgens  
Synergistic compositions for inhibiting the action of androgens comprise the combination in a single topical preparation of a 5α-reductase enzyme inhibitor and an androgen receptor blocking agent...
4681753 Pharmaceutical compositions having antineoplastic activity  
Pharmaceutical compositions endowed with antineoplastic activities, containing bivalent negative selenium, for instance as diselenide; carboxylic acids, aldehydes or ketones having odd number of...
4670426 Interruption of fertility in mammals by post-coital pills  
There are provided post-coital contraceptive pharmaceutical compositions comprising a blocker of progesterone activity (antiprogesterone) at comparatively high dosage, or a combination of such...
4657901 Pharmaceutical composition  
The present invention concerns a composition for topical application which is greatly useful for the treatment of acne. The composition contains (1) a compound of the formula: ##STR1## or its ester...
4639439 Contraceptive composition  
The invention relates to a contraceptive composition of a prolactin elevag benzamide, such as N-[(1-ethyl-2-pyrrolidinyl)methyl]2-methoxy 5-sulfamoyl benzamide, and a progestogen.
4628052 Pharmaceutical compositions containing dehydroepiandrosterone and other anesthetic steroids in the treatment of arthritis and other joint disabilities  
The present invention is concerned with compositions and methods of treating rheumatoid arthritis, osteoarthritis, and arthritis associated with psoriasis and with lupus and other auto-immune...
4626531 Prostaglandins and antigestagens for induction of labor and for abortion  
A pharmaceutical composition containing a prostaglandin and an antigestagen is suitable for induction of labor and for abortion.
4622316 13-thiaprostaglandins having cytoprotective activity  
13-thiaprostaglandins of Formula I ##STR1## wherein B is --CH 2 --CH 2 -- or --CHCH--, R 1 is phenyl, CH 3 , or NH 2 , R 2 is H or CH 3 , and R 3 is pentyl, hexyl, 1-methylpentyl,...
4604384 Pharmaceutical gel composition  
A composition for use for the treatment of burns, cuts, wounds, abrasions and the like, comprises a pharmaceutically acceptable glycol, preferably propylene glycol, and a cellulose derivative,...
4598072 Combinations of an aromatase-inhibitor and an antiandrogen for prophylaxis and/or treatment of benign prostatic hyperplasia  
A combination of an aromatase-inhibitor and an antiandrogen in a weight ratio of aromatase-inhibitor to antiandrogen of 20:1 to 1:1 is useful in a method of prophylaxis and/or of treatment by...
4588717 Compounds and vitamin supplements and methods for making same  
The present invention relates to novel compounds, vitamin supplements, diet pills, and methods for making the same. The vitamin supplements include one or more phytosterol esters, such as esters of...
4579844 Topical anti-inflammatory drug therapy  
A pharmaceutical composition for topical treatment of cutaneous disorders or disruptions characterized by skin inflammation or hyperproliferative epidermal activity comprises the combination of a...
4537776 Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone  
Topical pharmaceutical compositions comprising a pharmaceutically-active agent and a novel, penetration-enhancing vehicle or carrier are disclosed. The vehicle or carrier comprises a binary...
4514384 Hemorrhoid treatment method  
A method of treating hemorrhoids by applying to hemorrhoidal tissues a composition including by weight carbamide peroxide or benzoyl peroxide in an amount of between about 2% and 40%,...
4512987 New pharmaceutical preparations  
The invention concerns new pharmaceutical preparations for topical administration, such as creams, ointments, foams, pastes or gels, which contain the anti-inflammatorily active glucocorticoid...
4485054 Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)  
This invention provides an improved procedure for producing large multilamellar lipid vesicles (MLV), which may be used to encapsulate a biologically active material, particularly lipophilic...
4478818 Ocular preparation housing steroid in two different therapeutic forms  
An ocular insert and an ocular composition are disclosed. The insert and the composition comprises a steroid in two different forms.
4478822 Drug delivery system utilizing thermosetting gels  
This invention relates to a unique drug delivery system for delivering drugs to a body cavity. The drug delivery system comprises a medicament and a polymer such that the drug delivery system is a...
4474753 Topical drug delivery system utilizing thermosetting gels  
This invention relates to a unique drug delivery system for application to the skin which drug delivery system is a liquid at room temperature, but when administered topically to the skin becomes a...
4474751 Ophthalmic drug delivery system utilizing thermosetting gels  
This invention describes the application of selected polymers as novel drug delivery systems which use the body temperature and pH to induce a liquid to gel transition of the polymer which contains...
4454118 Method of treating psoriasis  
A cosmetic composition and a process for alleviating dry skin conditions of the hands, feet, cuticle, neck and facial areas and psoriasis comprising an admixture of lanolin, petrolatum and...
4451405 11α-Amino-3β-hydroxy-androstanes  
Compounds of the formula ##STR1## wherein R 1 is a C 1 -8 alkyl group or a C 3 -7 cycloalkyl group, and R 2 is a C 1 -6 alkyl group or a C 3 -6 cycloalkyl group and the D-homo analogues thereof...
4439432 Treatment of progesterone deficiency and related conditions with a stable composition of progesterone and tocopherols  
This invention relates to the composition of a biologically compatible high concentration solution of progesterone, which is stable and non-toxic, and which can be used transdermally, orally, and...
4404199 Salification products of cholic acids with trimethoxy-3,4,5-benzoic ester of 2-phenyl-2-dimenthylaminobutanol, having pharmacotherapeutic action, process for their preparation and therapeutic compositions containing them as active principle  
Salification products between cholic acids (chenodeoxicholic and ursodeoxycholic acid) and trimebutyne in the molar ratio 1:1 or 2:1 have been prepared. These new salts show a pharmacotherapeutic...
4390532 Topical combinations of an α-estradiol with a methyl xanthine  
Topical compositions comprising an active ingredient selected from at least two of the following three classes of compounds: (a) N-methyl-substituted xanthines containing at least two methyl...
4381298 Oral male contraceptive composition  
A male contraceptive composition is described that may be administered orally. This permits adjusting the dose of the constituents to provide for sperm production inhibition and for normal...