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4898856 |
Method for treating central nervous system diseases
A method of treating humans suffering from central nervous system diseases, such as Alzheimer's disease, Parkinson's disease, senile dimentia. The treatment consists of inducing into the patient's...
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4898857 |
Treating control nervous system diseases
A method of treating humans suffering from central nervous system diseases, such as Alzheimer's disease, Parkinson's disease, senile dementia. The treatment consists of inducing into the patient's...
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4897389 |
Treating central nervous system diseases
A method of treating human suffering from central nervous system diseases, such as Alzheimer's disease, Parkinson's disease, senile dementia. The treatment consists of inducing into the patient's...
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4895715 |
Method of treating gynecomastia
A method of treating gynecomastia in noncastrated patients being treated with an antiandrogen for androgen-dependent diseases such as benign prostatic hypertrophy, who are in need of such treating...
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4889847 |
Prevention of glucocorticoid-induced skin atrophy
The present invention is directed to the topical administration of a retinoid-containing pharmaceutical composition for the prevention of glucocorticoid-induced skin atrophy.
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4888331 |
Coadministration of antigestagen and antiestrogen for gynecological disorders, abortion and labor induction
An agent containing at least one compound having antiprogestational activity and at least one compound having anti-estrogenic activity is disclosed. The agent is suitable for the induction of...
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4883660 |
Gel bases for pharmaceutical compositions
Gel bases for pharmaceutical compositions comprise from about 0.5 to about 10.0% by weight ethoxylated (2 to 30 moles of ethoxylation) behenyl alcohol and from about 90 to 99.5% of a glycol solvent...
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4882359 |
Azacycloalkane derivatives, absorption promoters containing the derivatives as the effective ingredient and external preparations containing the absorption promoters
An azacycloalkane derivative useful for promoting the absorption of a medicine, an absorption promoting agent comprising at least one of the azacycloalkane derivatives as the effective ingredient...
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4879287 |
Pharmaceutical composition
Pharmacuetical compositions for topical application to the skin are disclosed comprising the hydrated crystalline calcium salt of mupirocin and a corticosteriod intimately mixed therewith. The...
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4870067 |
Oxytocins and antigestagens in combination for induction of birth
A combination product contains oxytocin and/or an oxytocin analog and an antigestagen for induction of birth.
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4866049 |
Ophthalmic compositionn and method of using same
The present invention relates to ophthalmic compositions and their preparation and use. More specifically, the invention relates to ophthalmic compositions useful in the treatment of surface...
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4861783 |
4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases
Phenylquinolinecarboxylic acids and derivatives thereof, such as 2-(2'-Fluoro-1,1'-biphenyl-4-yl)-6-fluoro-3-methyl-4-quinoli
necarboxylic acid, or a sodium or potassium salt thereof, are useful...
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4855305 |
Compositions and methods of effecting contraception utilizing melatonin
A method of effecting contraception in human females comprises administering an ovulation-inhibiting amount of melatonin. Optionally, the melatonin is administered in combination with a progestogen...
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4855289 |
Combination of two active substances
The invention concerns the use of a compound with diuretic properties and of a magnesium supplementation in the form of magnesium monoaspartate hydrochloride, magnesium oxide, magnesium hydroxide...
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4804541 |
Transdermal administration using benzyl alcohol
A method, composition, and article for use in transdermal or percutaneous administration to humans of systemically active medicaments in the form of a solution in benzyl alcohol.
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4797402 |
Cooling anti-itch skin preparations
Cooling, anti-itch skin preparations in a hydrophilic base, comprising an anti-inflammatory corticosteroid, peppermint oil and urea.
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4791099 |
Method of treatment for central nervous system diseases such as Alzheimer's 's disease
A method of treating humans suffering from central nervous system diseases, such as Alzheimer's disease, cerebral atrophy, Parkinson's disease, senile tremor, essential tremor, and cerebellar...
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4775529 |
Steroid lotion
An improved lotion formulation for the topical administration of corticosteroids in a hydro-alcoholic base containing propylene glycol.
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4771042 |
Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments
A method of inhibiting angiogenesis in a warm blooded animal which comprises administering to said animal an anti-angiogenic effective amount of a compound of the formula: ##STR1## wherein the...
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4756907 |
Active/passive immunization of the internal female reproductive organs
Antibody or antigen containing microparticles for the active or passive immunization of the internal female reproductive organs, comprising: microparticles of an antigen or antibody incorporated in...
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4757056 |
Method for tumor regression in rats, mice and hamsters using hexuronyl hexosaminoglycan-containing compositions
Regression of established malignant tumors in rats, mice and hamsters is achieved with a combination of the heparin fragment hexuronyl hexosaminoglycan sulfate (HHS) together with a steroid such as...
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4732892 |
L-α-amino acids as transdermal penetration enhancers
The disclosed invention provides methods and compositions ulilizing L-α-amino acids for enhancing the rate of penetration through the skin of both topical medicaments and of drugs employed for...
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4720489 |
Hair growth modification with ornithine decarboxylase inhibitors
The rate and character of human hair growth including androgen-stimulated beard hair growth in intact, sexually mature males is altered by the topical application out of a dermatologically...
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4686103 |
Method of managing cattle breeding herds
Cattle breeding herds are managed for accelerated time-controlled calving, using groups of cows predicted to calve within a period of 10 days, 1000 to 10,000 units of purified porcine relaxin are...
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4684635 |
Compositions and methods for inhibiting the action of androgens
Synergistic compositions for inhibiting the action of androgens comprise the combination in a single topical preparation of a 5α-reductase enzyme inhibitor and an androgen receptor blocking agent...
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4681753 |
Pharmaceutical compositions having antineoplastic activity
Pharmaceutical compositions endowed with antineoplastic activities, containing bivalent negative selenium, for instance as diselenide; carboxylic acids, aldehydes or ketones having odd number of...
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4670426 |
Interruption of fertility in mammals by post-coital pills
There are provided post-coital contraceptive pharmaceutical compositions comprising a blocker of progesterone activity (antiprogesterone) at comparatively high dosage, or a combination of such...
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4657901 |
Pharmaceutical composition
The present invention concerns a composition for topical application which is greatly useful for the treatment of acne. The composition contains (1) a compound of the formula: ##STR1## or its ester...
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4639439 |
Contraceptive composition
The invention relates to a contraceptive composition of a prolactin elevag benzamide, such as N-[(1-ethyl-2-pyrrolidinyl)methyl]2-methoxy 5-sulfamoyl benzamide, and a progestogen.
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4628052 |
Pharmaceutical compositions containing dehydroepiandrosterone and other anesthetic steroids in the treatment of arthritis and other joint disabilities
The present invention is concerned with compositions and methods of treating rheumatoid arthritis, osteoarthritis, and arthritis associated with psoriasis and with lupus and other auto-immune...
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4626531 |
Prostaglandins and antigestagens for induction of labor and for abortion
A pharmaceutical composition containing a prostaglandin and an antigestagen is suitable for induction of labor and for abortion.
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4622316 |
13-thiaprostaglandins having cytoprotective activity
13-thiaprostaglandins of Formula I ##STR1## wherein B is --CH 2 --CH 2 -- or --CHCH--, R 1 is phenyl, CH 3 , or NH 2 , R 2 is H or CH 3 , and R 3 is pentyl, hexyl, 1-methylpentyl,...
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4604384 |
Pharmaceutical gel composition
A composition for use for the treatment of burns, cuts, wounds, abrasions and the like, comprises a pharmaceutically acceptable glycol, preferably propylene glycol, and a cellulose derivative,...
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4598072 |
Combinations of an aromatase-inhibitor and an antiandrogen for prophylaxis and/or treatment of benign prostatic hyperplasia
A combination of an aromatase-inhibitor and an antiandrogen in a weight ratio of aromatase-inhibitor to antiandrogen of 20:1 to 1:1 is useful in a method of prophylaxis and/or of treatment by...
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4588717 |
Compounds and vitamin supplements and methods for making same
The present invention relates to novel compounds, vitamin supplements, diet pills, and methods for making the same. The vitamin supplements include one or more phytosterol esters, such as esters of...
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4579844 |
Topical anti-inflammatory drug therapy
A pharmaceutical composition for topical treatment of cutaneous disorders or disruptions characterized by skin inflammation or hyperproliferative epidermal activity comprises the combination of a...
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4537776 |
Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
Topical pharmaceutical compositions comprising a pharmaceutically-active agent and a novel, penetration-enhancing vehicle or carrier are disclosed. The vehicle or carrier comprises a binary...
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4514384 |
Hemorrhoid treatment method
A method of treating hemorrhoids by applying to hemorrhoidal tissues a composition including by weight carbamide peroxide or benzoyl peroxide in an amount of between about 2% and 40%,...
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4512987 |
New pharmaceutical preparations
The invention concerns new pharmaceutical preparations for topical administration, such as creams, ointments, foams, pastes or gels, which contain the anti-inflammatorily active glucocorticoid...
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4485054 |
Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
This invention provides an improved procedure for producing large multilamellar lipid vesicles (MLV), which may be used to encapsulate a biologically active material, particularly lipophilic...
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4478818 |
Ocular preparation housing steroid in two different therapeutic forms
An ocular insert and an ocular composition are disclosed. The insert and the composition comprises a steroid in two different forms.
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4478822 |
Drug delivery system utilizing thermosetting gels
This invention relates to a unique drug delivery system for delivering drugs to a body cavity. The drug delivery system comprises a medicament and a polymer such that the drug delivery system is a...
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4474753 |
Topical drug delivery system utilizing thermosetting gels
This invention relates to a unique drug delivery system for application to the skin which drug delivery system is a liquid at room temperature, but when administered topically to the skin becomes a...
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4474751 |
Ophthalmic drug delivery system utilizing thermosetting gels
This invention describes the application of selected polymers as novel drug delivery systems which use the body temperature and pH to induce a liquid to gel transition of the polymer which contains...
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4454118 |
Method of treating psoriasis
A cosmetic composition and a process for alleviating dry skin conditions of the hands, feet, cuticle, neck and facial areas and psoriasis comprising an admixture of lanolin, petrolatum and...
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4451405 |
11α-Amino-3β-hydroxy-androstanes
Compounds of the formula ##STR1## wherein R 1 is a C 1 -8 alkyl group or a C 3 -7 cycloalkyl group, and R 2 is a C 1 -6 alkyl group or a C 3 -6 cycloalkyl group and the D-homo analogues thereof...
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4439432 |
Treatment of progesterone deficiency and related conditions with a stable composition of progesterone and tocopherols
This invention relates to the composition of a biologically compatible high concentration solution of progesterone, which is stable and non-toxic, and which can be used transdermally, orally, and...
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4404199 |
Salification products of cholic acids with trimethoxy-3,4,5-benzoic ester of 2-phenyl-2-dimenthylaminobutanol, having pharmacotherapeutic action, process for their preparation and therapeutic compositions containing them as active principle
Salification products between cholic acids (chenodeoxicholic and ursodeoxycholic acid) and trimebutyne in the molar ratio 1:1 or 2:1 have been prepared. These new salts show a pharmacotherapeutic...
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4390532 |
Topical combinations of an α-estradiol with a methyl xanthine
Topical compositions comprising an active ingredient selected from at least two of the following three classes of compounds: (a) N-methyl-substituted xanthines containing at least two methyl...
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4381298 |
Oral male contraceptive composition
A male contraceptive composition is described that may be administered orally. This permits adjusting the dose of the constituents to provide for sperm production inhibition and for normal...
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