Patents in Class 514/17

Matches 1 - 50 out of 831

Match	Document	Document Title
1	7618944	Encapsulated amyloid-beta peptides The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
2	7615533	TPO peptide compounds for treatment of anemia Peptide compounds that bind to and activate the thrombopoietin receptor (c-mpl or TPO-R) or otherwise act as a TPO agonist are disclosed.
3	7612044	Melanoma antigens and their use in diagnostic and therapeutic methods The present invention provides a nucleic acid sequence encoding a melanoma antigen recognized by T lymphocytes, designated MART-1. This invention further relates to bioassays using the nucleic acid...
4	7608591	Targeted delivery to legumain-expressing cells The present invention relates to new agents and methods useful for preventing, treating and diagnosing diseases such as cancer. For example, the invention relates to prodrug agents useful for...
5	7608589	Peptidyl diacylglycerides Peptide and peptides that may be covalently linked to a lipid and methods of using such peptides and lipopeptides to prevent or treat disease are disclosed herein.
6	7601685	Growth factor modified protein matrices for tissue engineering Proteins are incorporated into protein or polysaccharide matrices for use in tissue repair, regeneration and/or remodeling and/or drug delivery. The proteins can be incorporated so that they are...
7	7598342	Alpha-fetoprotein peptides and uses thereof The invention relates to compounds that include peptide and peptidomimetics that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell...
8	7595299	Peptides as NS3-serine protease inhibitors of hepatitis C virus The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses...
9	7592009	Polypeptide ligands for targeting cartilage and methods of use thereof Ligands that specifically bind to articular cartilage tissues are disclosed, including uses for targeting therapeutics towards articular cartilage tissue and new materials for articular cartilage....
10	7589058	Ghrelin analogs The invention comprises peptidyl analogs that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.
11	7582725	Agents, which inhibit apoptosis in cells that are involved in wound healing The invention relates to the use of substances as a fundamental constituent in wound healing agents. The invention is characterised in that said substances bond to either IAP and/or integrin α v...
12	7582609	Method for the treatment of skin fibrosis and suitable compositions for such treatment A Method for the treatment of skin fibrosis with a peptide that inhibits TGF-β, and suitable compositions for its administration. The method includes in particular, the use of peptide P144, a...
13	7582312	Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof Methods of producing lung surfactant formulations through solvent dissolution and lyophilization are described as well as surfactant formulations derived therefrom. Methods of treating respiratory...
14	7579322	Compositions and methods for promoting myocardial and peripheral angiogenesis Methods, compositions and devices are disclosed for use in growing new blood vessels to restore or improve blood flow to ischemic tissues and organs of the body. Compositions comprising IGD...
15	7579320	IAP BIR domain binding compounds Disclosed is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I or II or a salt thereof, in which R 1 , R 2 , R 3 , R 100 , R 200 , R 300 , A, A 1 , BG, Q...
16	7579319	Methods for improving the structure and function of arterioles The present invention relates to the unexpected finding that vessels smaller than even the smallest arteries (i.e. arterioles) thicken, become dysfunctional and cause end organ damage to tissues as...
17	7579313	Transglutaminase inhibitors and methods of use thereof Transglutaminase inhibitors and methods of use thereof are provided.
18	7576175	Alpha-4 beta-1 integrin ligands for imaging and therapy The present invention provides α 4 β 1 integrin ligands that display high binding affinity, specificity, and stability. The ligands comprise a peptide having n independently selected amino...
19	7576056	Peptides and compounds that bind to a receptor Peptide compounds that bind to and activate the thrombopoietin receptor (c-mpl or TPO-R) or otherwise act as a TPO agonist are disclosed.
20	7569547	Inhibiting furin with polybasic peptides Small, polybasic peptides are disclosed that are effective as furin inhibitors, e.g. hexa- to nona-peptides having L-Arg or L-Lys in most positions. Removing the peptide terminating groups can...
21	7553876	Polycationic compounds and uses thereof Aspects of the present invention relate to compounds and methods useful in modulating angiogenesis and methods of treating or preventing diseases associated with angiogenesis by administering a...
22	7550438	Methods for production of growth-promoting proteins and peptides for kidney epithelial cells Novel growth peptides derived from protein factors having molecular weights of about 22 and 45 kDa stimulate mitogenic activity of epithelial, but not fibroblastic cells, in particular, kidney...
23	7550437	Compositions for preventing and treating digestive organs diseases The present invention provides a composition for safely and effectively preventing and treating digestive organs diseases, particularly, gastric ulcer, duodenal ulcer, gastritis, diarrhea,...
24	7547676	Antagonist peptides to the C5A chemotactic function of vitamin D binding protein It has been demonstrated that one of Vitamin D Binding Protein (DBP) biological functions is to enhance the chemotactic activity of C5 a and C5 a des Arg. The present invention has found that...
25	7544653	Additive cytoprotective effects of two bioactive regions of pro-opiomelanocortin hormone Repetitive and bioreactive regions of pro-opiliomelanocortin were identified using computational analysis. These regions KOMET, KOMET-1, KOMET-2, and KOMET-3 exhibit cytoprotective effects and may...
26	7541339	Par-2-activating peptide derivative and pharmaceutical composition using the same The present invention relates to a peptide derivative represented by the general formula (I) or a salt thereof: Z-(CH 2 ) n —CO—NH-Leu-Ile-Gly-AA 1 -AA 2 -CO—R (I) wherein Z represents an...
27	7538089	Anti-inflammatory compounds and uses thereof The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides...
28	7534438	Product and process for liquefaction of mucus or sputum Disclosed are compositions and methods for decreasing the viscosity and/or cohesiveness of and/or increasing the liquefaction of excessively or abnormally viscous or cohesive mucus or sputum. The...
29	7534431	Methods and compositions for administering therapeutic and diagnostic agents Methods and compositions are described for targeting therapeutic and diagnostic molecules to particular types of cells using targeting antibodies or other targeting moeities.
30	7528227	Histone H2A peptide derivatives and uses thereof Peptides derived from a segment of human histone H2A, the segment corresponding to amino acid residues 36-44 of human histone H2A, are capable of reducing or ameliorating the extent of injury...
31	7521529	Differentially protected orthogonal lanthionine technology The present invention provides a method of synthesizing an intramolecularly bridged polypeptide comprising at least one intramolecular bridge. The present invention further provides a method of...
32	7521415	Methods of intracellular peptide delivery Methods and kits for transporting heterologous compounds into cells, particularly mammalian cells, are disclosed. The method involves the pretreatment of the cell with a polycation, cationic...
33	7517857	Immune-modulating peptide Disclosed are peptides having SEQ ID NOs: 1 to 24 that induce superoxide generation by human monocytes or neutrophils; that induce an intracellular calcium increase by human peripheral blood...
34	7517855	Peptides which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, compositions and uses thereof The present invention relates generally to peptides, which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, methods of making peptides, which inhibit angiogenesis, cell...
35	7507718	Polymyxin B analogs for LPS detoxification The invention relates to SAEP II peptide dimers that mimic polymyxin B i.a. in its ability to bind non-covalently the lipopolysaccharide (LPS) of Gram-negative bacteria with high affinity, and...
36	7504086	Structure and method for releasing substance therefrom A structure comprises at least a porous body holding a substance releasably, comprising a capping member for keeping the substance inside the pore and/or on at least a part of the entire surface of...
37	7501486	Peptides that selectively home to heart vasculature and related conjugates and methods The present invention provides a variety of isolated peptides and peptidomimetics, which can be useful, for example, in constructing the conjugates of the invention or, where the peptide itself has...
38	7498297	Medicinal uses of mu-opioid receptor agonists The present invention provides methods for stimulating a mu-opioid receptor agonist peptide in a mammal in need thereof. The methods comprise administering to the mammal an effective amount of a...
39	7491702	Polypeptides related to amyloid precursor protein, pharmaceutical compositions thereof, and methods of treatment using the same The invention provides compounds having formulae comprising X 1 -Ser-Met-Arg-Glu-Arg-X 2
40	7491699	Peptide nanostructures and methods of generating and using the same A tubular or spherical nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids...
41	7491691	Connective tissue stimulating peptides Novel peptides are described which comprise an amino acid motif selected from the group consisting of “PG”, “GP”, “PI” and “IG” and having up to 10 amino acids upstream and/or...
42	7482429	Kahalalide F and related compounds A process is provided for preparing kahalalide F and which leads to other kahalalide mimic compounds having useful biological activity.
43	7476650	Enzyme inhibition Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases. The activities of...
44	7470658	Methods for inhibiting tumor metastasis, and peptides useful therefor In accordance with the present invention, there are provided peptides that bind to a member of the mammalian selectin family and inhibit the binding of a carbohydrate to the selectin. Invention...
45	7456253	Growth hormone releasing peptides Disclosed are peptide and peptidomimetic compounds generally according to formula (I), and pharmaceutically acceptable salts thereof, that are useful as GHRP analogs: R 1 -A 2 -A 3 -A 4 -A 5 -R 2 ...
46	7439231	Inhibitors of antigen presentation by MHC class II molecules and methods of use thereof The present invention relates to compounds, pharmaceutical compositions containing such compounds and methods for their use. In particular, the compounds of the invention are useful for the...
47	7425541	Enzyme-cleavable prodrug compounds The prodrug of the invention is a modified form of a therapeutic agent and comprises a therapeutic agent, an oligopeptide, a stabilizing group and, optionally, a linker group. The prodrug is...
48	7423116	Pentapeptide compounds and uses related thereto Pentapeptide compounds are disclosed. The compounds have biological activity, e.g., cytotoxicity. Prodrugs having targeting groups and pentapeptide moieties, as well as precursors thereof are also...
49	7423021	Peptidic thrombin inhibitors The invention relates to biologically active molecules, which interact with and inhibit thrombin. The invention particularly relates to molecules of general formula (I): Y 1 —(NH—X 1...
50	7423020	Treatment of mood disorders by administration of SMR1 This invention relates to the use of an agent that modulates the interaction between a SMR1 peptide and a metal-lopeptidase for the preparation of a medicament for preventing or treating a Central...

Matches 1 - 50 out of 831

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