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7417037 |
Compositions and methods of treatment for inflammatory diseases
Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain...
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7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
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7208483 |
Polymeric delivery agents and delivery agent compounds
Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are...
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7094431 |
Method of healing skin wounds in mammals and a composition therefor
This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or...
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7049308 |
C-nitroso compounds and use thereof
A C-nitroso compound having a molecular weight ranging from 225 to 1,000 (from 225 to 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon,...
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6833362 |
Method and composition for the accelerated in vivo removal of ethanol
A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or...
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6730329 |
Zinc containing compositions for anti-viral use
One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one...
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6706290 |
Methods for eradication of nanobacteria
Nanobacteria contribute to pathological calcification in the human and animal body, including diseases such as kidney stones, salivary gland stones, dental pulp stones and atherosclerosis. The...
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6624153 |
Halogenated antituberculosis agents
Halogenated derivatives of two synthetic anti-tuberculosis agents, thioacetazone and p-aminosalicylic acid, have been synthesized. In general, the halogenated compound has the structure of...
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6620785 |
Treatment of Mycobacterial diseases by administration of bactericidal/permeability-increasing protein products
The present invention relates to methods for treating a subject suffering from infection with Mycobacteria, such as M. leprae or M. tuberculosis comprising administering to the subject a...
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6593339 |
Use of compounds as antibacterial agents
The present invention discloses a new use of NO-releasing NSAIDs, especially NO-releasing NSAIDs of the formula I, or a pharmaceutically acceptable salt or enantiomer thereof, for the manufacture...
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6455515 |
Salicylohydrazide derivatives, processes and intermediates for their preparation, compositions comprising them, and their use
Salicylohydrazide derivatives of the formula I in which the index and the substituents have the following meanings: X is halogen, NO 2 , cyano, alkyl or alkoxy; m is 0, 1, 2 or 3, it being...
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6426338 |
Therapy for constipation
Compositions comprising colchicine and at least one amino-salicylic acid derivative, preferably olsalazine is used for treatment of prophylaxis of constipation.
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6326364 |
Use of 5-aminosalicylates as antimicrobial agents
A method of inhibiting the growth of a bacterial species in a human or non-human vertebrate employs the antimicrobial (i.e., antibiotic) properties of 5-aminosalicylates. These antimicrobial...
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6287601 |
Topical nitric oxide donor compositions
Compositions and methods of the topical treatment of equine laminitis are disclosed. In particular, combinations of a fast acting nitric oxide (NO) donor, a sustained acting NO donor and an NSAID...
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6277412 |
Pellet-type formulation intended for treating the intestinal tract
An orally adminsterable pharmaceutical pellet formulation for the treatment of the intestinal tract is disclosed, which comprises a core and an enteric coating, the core including, as a...
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6255298 |
Macrophage scavenger receptor antagonists for use in the treatment of cardiovascular diseases
Salicylanilide derivatives which are macrophagescavenger receptor antagonists are provided. Methods of treating cardiovascular disease comprising administration of the present compounds are also...
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6225296 |
Inhibitory effects of synthetic and natural colorant on carcinogenesis VIII
A method of inhibiting Epstein-Barr virus early antigen induction in Epstein-Barr virus genome-carrying cells which have been cultivated in vitro in a medium containing at least one chemical...
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6177414 |
Starburst conjugates
Starburst conjugates which are composed of at least one dendrimer in association with at least one unit of a carried agricultural, pharmaceutical, or other material have been prepared. These...
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6143735 |
Agent for treating heart diseases
Vitamin E acts to enhance and improve the effect upon oral administration of coronary active vasodilators and/or blood circulation-promoters. The new use and new agents containing vitamin E are...
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6143734 |
Nitroso esters of β-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs
A compound comprising a non-steroidal antiinflammatory agent to which is directly or indirectly linked an NO group, a compound comprising an enolic anilide non-steroidal antiinflammatory agent to...
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6117859 |
Method of relieving chronic inflammation by using 5-alkylsulfonylsalicylanilides
A method of treating chronic inflammation in a mammal is disclosed which comprises contacting the affected area with an amount sufficient to ameliorate the inflammatory condition, of a compound of...
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6045827 |
Treatment of equine laminitis
Compositions and methods of the topical treatment of equine laminitis are disclosed. In particular, combinations of a fast acting nitric oxide (NO) donor, a sustained acting NO donor and an NSAID...
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6043232 |
Nitroso esters of beta-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs
A compound comprising a non-steroidal antiinflammatory agent to which is directly or indirectly linked an NO group, a compound comprising an enolic anilide non-steroidal antiinflammatory agent to...
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5958911 |
Method of relieving inflammation by using 5-alkylsulfonylsalicylanilides
A method of treating inflammation in a mammal, which comprises contacting the affected area with an amount sufficient to ameliorate the inflammatory condition, of a compound of the following...
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5905073 |
Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents
The present invention provides a method of colon cancer chemoprevention or chemotherapy comprising administering to an individual suffering from colon cancer or at risk to develop colon cancer a...
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5889026 |
4-hydroxy-piperodine derivatives
The present invention relates to compounds of the formula ##STR1## wherein x is --O--, --NH--, --CH 2 --, --CH, --CO 2 --, --CONH--, --CON(lower alkyl)--, --S-- and --SO 2 --; R 1 -R 4 ...
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5869471 |
Methods for the treatment of arthritis using phosphonates and NSAIDS
The present invention provides methods of treating a human or other animal subject afflicted with arthritis, including rheumatoid, arthritis and osteoarthritis, comprising a sixty (60)-day...
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5869067 |
Bi-aromatic compounds and pharmaceutical and cosmetic compositions
The present invention relates to new aromatic compounds, to their preparation and to their use in human and veterinary medicine and in cosmetic compositions.
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5750559 |
Potentiation of the antireactive-antiasthmatic effect of inhaled loop diuretics by inhaled non-steroidal anti-inflammatory drugs
The antireactive-antiasthmatic effect of inhaled loop diuretics is potentiated by the use of a combination of a loop diuretic and a non-steroidal anti-inflammatory drug as an inhalant for combating...
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5731302 |
Stable aqueous suspensions of mesalazine
The invention discloses new compositions of mesalazine in the form of aqueous suspensions, characterized in that they are more stable than those of the prior art. The compositions contain colloidal...
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5725872 |
Composition for foams, notably rectal foams, and foams thus obtained
A composition for a foam and a process for preparing it are provided, the composition including by weight (a) more than 25% of an active ingredient in powder form; (b) from 1 to 20% of a...
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5716648 |
Compositions for use in the regulation of subnormal pH values in the intestinal tract and for treatment of bowel diseases
Compositions for use in the regulation of subnormal pH values in intestinal tract and for treatment of bowel diseases. The compositions comprise a coating and a substantially insoluble alkaline...
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5668123 |
Method of maintaining remission from venous ulcers with sulphasalazine and its metabolite
Method of treating venous insufficiency and venous ulcers by administering to a patient in need thereof an effective amount of sulphasalazine or 5-aminosalicylic acid.
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5583113 |
Use of a direct-acting thrombin inhibitor for the manufacture of a medicinal product having thrombolytic activity
A method for inducing thrombolysis, which method comprises administering to a patient a thrombolytically effective amount of a thrombin inhibitor which acts at the active site of thrombin, in the...
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5541171 |
Orally administrable pharmaceutical composition
A solid dosage form, such as a capsule or tablet, containing a pharmacologically active agent is coated with an anionic polymer, which is insoluble in gastric juice and in intestinal juice below...
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5541170 |
Orally administrable pharmaceutical compositions
A solid dosage form, such as a capsule or tablet, containing a pharmacologically active agent is coated with an anionic polymer, which is insoluble in gastric juice and in intestinal juice below...
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5527523 |
Hydroquinone amino-acid esters, methods of preparation, and pharmaceutical or cosmetic compositions containing them
Hydroquinone amino-acid esters having formula (I), pharmaceutical or cosmetic compositions containing them, particularly dermatological compositions having pigment-removing activity, and the...
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5519014 |
Treatment of non-inflammatory and non-infectious bowel disorders
A medicine for treating non-inflammatory and non-infectious bowel disorders, such as irritable bowel syndrome, constipation, non-ulcer dyspepsia, gastro-oesophageal reflux with or without...
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5405842 |
Treatment of steroid dependent asthmatics
A method for the treatment of asthma, particularly corticosteroid dependent asthma with "steroid sparing" effect, but without serious toxicities prevalent with common "steroid sparing" treatments...
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5366967 |
Potentiation of the anti-reactive-antiasthmatic effect of inhaled loop diuretics by inhaled non-steroidal anti-inflammatory drugs
The antireactive-antiasthmatic effect of inhaled loop diuretics is potentiated by the use of a combination of a loop diuretic and a non-steroidal anti-inflammatory drug as an inhalant for combating...
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5352681 |
Pharmaceutical enema preparation
The light, oxidation and storage stability of aqueous 5-ASA suspensions is increased by incorporating in such suspensions an effective amount of titanium dioxide. The resulting stabilized aqueous...
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5211947 |
Method for lowering blood cholesterol levels with granulocyte-macrophage colony stimulating factor
A method for lowering the blood cholesterol levels in mammals and humans by administering GM-CSF is disclosed.
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5151415 |
Method of treating a papova-type viral infection
A method for treating an epithelial tumor of a viral infection involves repeated applications of a paste of acetylsalicylic acid and water to the infection until it is arrested.
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5140020 |
Derivative of dihydroxybenzamide and a pharmaceutical composition thereof
Disclosed herein are a derivative of dihydroxybenzamide represented by the formula(I): ##STR1## wherein (1) R 1 represents a hydrogen atom or a lower alkyl group and R 2 represents a straight...
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5082651 |
Pharmaceutical compositions
Pharmaceutical compositions suitable for intra-rectal administration in the form of a foam are described which comprise a therapeutically effective amount of 5-aminosalicylic acid, a...
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5053228 |
Polymeric temperature sensitive drug carrier
The drug carrier of this invention provides a temperature-sensitive polymer chemically bonded to a drug. The drug carrier is capable of releasing a drug continuously in the body. The drug carrier...
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5041431 |
Pharmaceutical composition and method for the treatment of colitis ulcerosa and Crohn's disease by oral administration
A pharmaceutical composition containing as active ingredient 5-aminosalicyclic acid or a pharmaceutically acceptable salt or ester thereof allow the treatment of colitis ulcerosa or Crohn's disease...
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5010069 |
Stable liquid form of 5-aminosalicylic acid
An aqueous solution of 5-aminosalicylic acid (5-ASA) and a nontoxic alkali, alkali metal or alkaline earth metal salt of 5-aminosalicylic acid having a pH of 3-5 is disclosed. The sole buffer in...
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4987133 |
Salicylic acid derivatives
New salicylic acid derivatives of the general formula I ##STR1## in which R 1 is H or CH 3 , R 2 is 4-(4-methyl-2-thiazolyl)-piperazino, 4-(tetrahydro-2-furoyl)-piperazino,...
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