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5441963 |
Potentiation of NMDA antagonists
The present invention is directed to a composition and method for poteniating the therapeutic effects of a class of known NMDA antagonists.
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5374633 |
Imidazole dermal penetration enhancers
Topically administerable compositions are described which contain, in a pharmaceutically acceptable vehicle, a combination of a drug whose dermal penetration can be enhanced and a combination of...
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5369021 |
Microorganism for selective production of a specific compound of avermectin and a method for selective production thereof
A microorganism for selective production of a specific compound of avermectin having one or more of the following properties: specific accumulation of avermectin compound "a", effective...
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5366967 |
Potentiation of the anti-reactive-antiasthmatic effect of inhaled loop diuretics by inhaled non-steroidal anti-inflammatory drugs
The antireactive-antiasthmatic effect of inhaled loop diuretics is potentiated by the use of a combination of a loop diuretic and a non-steroidal anti-inflammatory drug as an inhalant for combating...
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5312818 |
Method of protecting against and/or treating ulcerative gastrointestinal conditions using a thromboxane A.sub.2 receptor antagonist and combination useful in preventing and/or treating ulcers and/or inflammation
A method is provided for protecting against and/or treating ulcerative gastrointestinal conditions, including anti-inflammatory drug-induced gastrointestinal ulcers, using a thromboxane A 2 ...
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5260289 |
Composition for treating pain, method for treating pain and composition for reinforcing pain relief action
A composition for treating pain, which contains dibucaine, a pharmaceutically acceptable salt of salicylic acid, calcium bromide, and antiphlogistic steroid(s) as active ingredients; and a method...
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5248505 |
Method for treating gastrointestinal distress
This invention relates to a pharmaceutical composition for treating gastrointestinal distress comprising an effective amount of an antidiarrheal composition, e.g. loperamide, and an antiflatulent...
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5215977 |
Method for treating leg weakness in fowl
A method of treating poultry suffering from leg bone joint infection and/or leg weakness by administering to the poultry an effective amount of a non-steroidal anti-inflammatory drug and...
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5206155 |
Microorganism for selective production of a specific compound of avermectin and a method for selective production thereof
A microorganism for selective production of a specific compound of avermectin having one or more of the following properties: specific accumulation of avermectin compound "a", effective...
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5152988 |
Imidazole compounds in compositions and methods in thrombolytic therapy
The use of imidazoles of the formula ##STR1## and imidazolium salts of the formula ##STR2## in thromobolytic therapy are described.
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5132106 |
Halogenated pyrimidine 3-oxide derivatives, their use for the treatment and prevention of hair loss and for stimulating its regrowth
The invention relates to compounds of formula: ##STR1## in which: R 1 and R 2 denote, independently of one another, a hydrogen atom or alternatively a carbamoyl group of formula: ##STR2## with R'...
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5128334 |
Analgesic and anti-inflammatory medicine
A composition containing ascorbic acid and/or its derivatives and aspirin and/or its derivatives is an effective analgesic and anti-inflammatory medicine. A method for reducing the side effects of...
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5098707 |
Imidazole compounds and their use as transglutaminase inhibitors
Compositions useful for thrombolytic therapy comprising a plasminogen activator such as tPA or streptokinase together with an imidazolium salt having the formula ##STR1## in a pharmaceutically...
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5071842 |
Aspirin-containing composition including diphenhydramine and an alkalizing agent to reduce gastrointestinal injury potential
A nonsteroidal anti-inflammatory drug composition containing as protectants against gastrointestinal injury, H 1 blockers, H 2 blockers, beta-adrenergic agonists, or combinations thereof, and an...
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5070085 |
Compositions and methods for administering therapeutically active compounds
A composition useful for administering therapeutically active compounds to improve the body absorption and/or retention thereof comprising a composition includes a therapeutically active compound...
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5063220 |
Parenteral formulations of 1-diphenylmethyl-4-((2-(4-methylphenyl)-5-methyl-1H-imidazol-4-yl)methyl )piperazine
A pharmaceutical formulation suitable for parenteral (preferably intravenous) administration includes an effective amount of...
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5055460 |
Method for weight loss
A method for producing or maintaining weight loss by administering to a human a composition containing an effective amount of each of caffine, aspirin and ephedrine. The pharmaceutical composition...
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5041430 |
Oral anticoagulant/platelet inhibitor low dose formulation
There are disclosed combination products useful for the treatment and/or prevention of a first or recurrent myocardial infarction or a first or recurrent stroke. Said combination products comprise...
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5004736 |
Procedure for obtaining the preparation for the treatment of the disease psoriasis: drug for the treatment of psoriasis and its application
The invention refers to the obtaining of the preparation for the treatment of the skin disease psoriasis. The object of the invention is a medicinal agent based on two corticosteroids, salicylates...
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4987133 |
Salicylic acid derivatives
New salicylic acid derivatives of the general formula I ##STR1## in which R 1 is H or CH 3 , R 2 is 4-(4-methyl-2-thiazolyl)-piperazino, 4-(tetrahydro-2-furoyl)-piperazino,...
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4981681 |
Lotion mixture and method of treating psoriasis
A combination of ingredients consisting of a mixture of predetermined proportions of Purified Water, Methylparaben, Potassium Hydroxide, Hydrogenated Coconut Oil, Glycerine, Polysorbate 60,...
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4975426 |
Cough/cold mixtures comprising non-sedating antihistamine drugs
Pharmaceutical compositions and methods of using same comprising aspirin, sodium salicylate, salicylamide or acetaminophen, in combination with a non-sedating antihistamine and optionally one or...
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4973474 |
2,4-diaminopyrimidine 3-oxide derivatives and their use for the treatment and prevention of hair loss
New 2,4-diaminopyrimidine 3-oxide derivatives and their use for the treatment and the prevention of hair loss. The compounds correspond to the formula: ##STR1## in which: R 1 and R 2 denote...
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4971960 |
Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids
Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid nucleus bearing a substituent in position 1 and 4. The nucleus may be optionally substituted at...
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4943565 |
Analgesic tablet of aspirin and caffeine containing low-substituted hydroxypropyl cellulose
An analogesic tablet containing aspirin, acetaminophen and caffeine of improved dissolution rate containing low-substituted hydroxypropylcellulose.
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4939145 |
Phenothiazone derivatives and analogs
Phenothiazone derivatives and analogs thereof, pharmaceutical compositions and methods of treatment are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As...
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4937236 |
Anxiolytic N-substituted benzamides
A method of treating anxiety including administering to a person to be treated an effective amount of compounds of the general formula: ##STR1## wherein the various substituents are defined...
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4925856 |
Aldoxime-substituted imidazolium derivatives useful in the treatment of poisoning by phosphorus-containing chemicals
A therapeutically effective class of low toxicity aldoxime-substituted functionalized imidazolium compounds and compositions is disclosed which is effective in the treatment of living species...
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4880791 |
Combination product composed of xanthine derivatives and O-acetylsalicylic acid or its pharmacologically tolerated salts, and its use
A combination product containing (A) on the one hand a xanthine derivative of the formula ##STR1## in which one of the radicals R 1 and R 3 represents a straight-chain alkyl, (ω-1)-oxoalkyl or...
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4877780 |
Antiemetic N-substituted benzamides
Compounds of the general formula: ##STR1## wherein the various substituents are defined hereinbelow have pharmacological properties rendering them useful as antiemetic agents with reduced...
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4859658 |
Compound compositions with improved analgesic antipyretic and anti-inflammatory activity
Pharmaceutical compositions containing thioacetamol and an amount of a non-steroidal anti-inflammatory drug selected from aspirin, indomethacin, dichlofenac, naproxen, sulindac and fenbufen...
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4857517 |
Quinuclidyl benzoxepins as 5-HT.sub.3 antagonists
Certain specific substituted 9-N-(1-azabicyclo-[2.2.2.]octan-3-yl)carboxamido-2,3,4,5-tet
rahydro-1-benz oxepins and their valuable use as 5-HT 3 antagonists having CNS and gastric prokinetic...
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4853376 |
Benzamides and benzoates having anti-emetic activity
Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein: X is NH; or O when Ar is of formula (a) and R 2 is hydrogen or when Ar is a group of formula (b); R 1 ...
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4810699 |
Substituted 1,3,4,9-tetrahydropyrano[3,4,-b]indole-1-acetic acids, pharmaceutical compositions containing them, and methods for treating inflammatory conditions and for analgesic purposes using them
Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid nucleus bearing a substituent in position 1,5, 6, 7 and 8. The derivatives are useful...
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4806530 |
Pharmaceutical compositions based on diltiazem and lysine acetylsalicylate
Pharmaceutical composition containing both diltiazem and lysine acetylsalicylate exhibits enhanced platelet aggregation inhibitory properties.
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4798811 |
Combination preparation
A combination of verapamil, gallopamil or anipamil and acetylsalicylic acid in a weight ratio of from 10:1 to 2:1 being useful in the treatment of circulatory disorders.
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4789667 |
External pharmaceutical composition and methods of use
A pharmaceutical composition for external use with the enhanced penetration of a pharmacologically active agent through the skin or mucosa of a warm-blooded animal, said composition comprising ...
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4743596 |
Anti-arthritic preparation
An anti-arthritic preparation consisting essentially of the anti-inflammatory, nonsteroidal agents aspirin and phenylbutazone, the anti-inflammatory corticosteroid prednisone, and the skeletal...
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4734405 |
Combination product
A combination of acetylsalicylic acid and pyridazinone derivatives can be used for the treatment of thromboembolic disorders.
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4727066 |
Esters of 1,4-dihydropyridines and medicaments containing the same
The preparation of esters of 1,4-dihydropyridine, useful in the prevention and treatment of cardiovascular disorders such as atheroma, of the formula ##STR1## wherein X is a phenyl moiety and Y is...
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4694024 |
Combination product composed of pyrimido-pyrimidines and O-acetylsalicylic acid or its pharmacologically tolerated salts, and its use
O-acetylsalicylic acid and a pyrimido-pyrimidine as combination products.
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4686212 |
Stable sodium aspirin tablet compositions
Compositions are provided for the preparation of stable sodium aspirin tablets. The compositions comprise dry, crystalline sodium aspirin, an anhydrous binder that is unreactive to sodium aspirin...
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4654331 |
Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group
The (5-R-2-oxo-1,3-dioxolen-4-yl)methyl moiety: ##STR1## wherein R is loweralkyl of 1-6 carbon atoms, especially methyl or t-butyl; when utilized as an ester on a pharmaceutical having a carboxylic...
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4650789 |
Method and composition for increasing production of serotonin
The production of the neurotransmitter serotonin is increased through administration of a therapeutic composition which includes L-tryptophan in combination with a salicylate, pyridoxine, niacin...
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4621094 |
Anti-histaminic pyridyl compounds
This disclosure describes compounds of formula I. ##STR1## wherein X is Cl or Br (including their pharmaceutically acceptable salts and esters) which have potent antihistamine activity and which...
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4551463 |
Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug
Certain substitute 1,8-naphthyridines and 1,5,8-azanaphthyridines are useful in treating and preventing ulcers in mammals. Methods for preparing the compounds and methods for their use are also...
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4545992 |
Pharmaceutical preparations
A pharmaceutical preparation for external use which comprises a solution of a non-steroid antipholgistic analgesic agent which is dissolved in at least one adjuvant selected from the group...
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4542127 |
Antidiabetic salicylic acid derivatives
Salicylic acid derivatives of the formula I ##STR1## wherein R 1 , W, X, Y and Z have the meanings indicated or a physiologically tolerated salt thereof, processes for their preparation,...
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4539315 |
Sublingually absorbable nontoxic aspirin composition
An analgesic aspirin composition in dosage form having acetylsalicylic acid and unreacted glycine in an amount equal to at least approximately 33.3% of the weight of the acetylsalicylic acid for...
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4534974 |
Pharmaceutical compositions with codeine
Compositions for the relief of pain, muscle spasm and limited mobility associated with acute painful muscoloskeletal conditions are disclosed. Such compositions comprise in combination, a...
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