Patents in Class 514/16

Matches 1 - 50 out of 799

Match	Document	Document Title
1	7612044	Melanoma antigens and their use in diagnostic and therapeutic methods The present invention provides a nucleic acid sequence encoding a melanoma antigen recognized by T lymphocytes, designated MART-1. This invention further relates to bioassays using the nucleic acid...
2	7608589	Peptidyl diacylglycerides Peptide and peptides that may be covalently linked to a lipid and methods of using such peptides and lipopeptides to prevent or treat disease are disclosed herein.
3	7605133	Isolated peptides to treat alpha-synuclein diseases The present invention relates to drug screening methods and methods of preventing neural tissue damage caused by α-synuclein aggregation. These methods are especially useful in the design and...
4	7598342	Alpha-fetoprotein peptides and uses thereof The invention relates to compounds that include peptide and peptidomimetics that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell...
5	7589064	Formulations of ramipril The present invention relates to stable tablet formulations of ramipril, optionally in combination with a diuretic.
6	7589058	Ghrelin analogs The invention comprises peptidyl analogs that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.
7	7588766	Treatment of amyloidogenic disease The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of Aβ in the brain of a patient. Such methods entail administering agents that induce...
8	7585509	Erb-2 receptor targeting peptide The ErbB-2 receptor, a member of the tyrosine kinase type 1 family of receptors, has been implicated in many human malignancies. Bacteriophage display technology was employed to identify peptides...
9	7582609	Method for the treatment of skin fibrosis and suitable compositions for such treatment A Method for the treatment of skin fibrosis with a peptide that inhibits TGF-β, and suitable compositions for its administration. The method includes in particular, the use of peptide P144, a...
10	7582603	Method for treating or inhibiting intestinal inflammation Peptide antagonists of zonulin are disclosed, as well as methods for the use of the same. The peptide antagonists bind to the zonula occludens receptor, yet do not physiologically modulate the...
11	7582312	Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof Methods of producing lung surfactant formulations through solvent dissolution and lyophilization are described as well as surfactant formulations derived therefrom. Methods of treating respiratory...
12	7579321	Pharmaceutical compositions including low dosages of desmopressin The present invention is directed to a pharmaceutical composition comprising 0.5 ng to 20 μg desmopressin and a pharmaceutically acceptable carrier. The present invention is also directed to a...
13	7579320	IAP BIR domain binding compounds Disclosed is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I or II or a salt thereof, in which R 1 , R 2 , R 3 , R 100 , R 200 , R 300 , A, A 1 , BG, Q...
14	7579313	Transglutaminase inhibitors and methods of use thereof Transglutaminase inhibitors and methods of use thereof are provided.
15	7576175	Alpha-4 beta-1 integrin ligands for imaging and therapy The present invention provides α 4 β 1 integrin ligands that display high binding affinity, specificity, and stability. The ligands comprise a peptide having n independently selected amino...
16	7569547	Inhibiting furin with polybasic peptides Small, polybasic peptides are disclosed that are effective as furin inhibitors, e.g. hexa- to nona-peptides having L-Arg or L-Lys in most positions. Removing the peptide terminating groups can...
17	7563772	Methods of increasing cerebral blood flow Methods of increasing blood flow in a mammalian brain blood vessel characterized by, or otherwise experiencing, decreased blood flow due to an ischemic or other hypoxic event, vasoconstriction or...
18	7557087	Compositions and methods for treating diseases This invention relates to compositions and methods for treatment of vascular conditions. The invention provides arginine polymers and arginine homopolymers for the treatment and/or prevention of...
19	7553876	Polycationic compounds and uses thereof Aspects of the present invention relate to compounds and methods useful in modulating angiogenesis and methods of treating or preventing diseases associated with angiogenesis by administering a...
20	7550438	Methods for production of growth-promoting proteins and peptides for kidney epithelial cells Novel growth peptides derived from protein factors having molecular weights of about 22 and 45 kDa stimulate mitogenic activity of epithelial, but not fibroblastic cells, in particular, kidney...
21	7547676	Antagonist peptides to the C5A chemotactic function of vitamin D binding protein It has been demonstrated that one of Vitamin D Binding Protein (DBP) biological functions is to enhance the chemotactic activity of C5 a and C5 a des Arg. The present invention has found that...
22	7544666	NAP derivatives An oligopeptide comprises formulae (I) or (II) the oligopeptide derivative thereof, and a pharmaceutical composition comprising the same are provided.
23	7541430	Peptides for use in treating obesity Novel cyclic and linear peptides of the formula R 1 —X—X 1 —X 2 —X 3 —X 4 —X 5 —X 6 —X 7 —X 8 —X 9 —X 10 —X 11 —R 2 are useful in the treatment of obesity are provided.
24	7531516	Peptidic compounds selectively binding to P-selectin The present invention relates to compounds which bind selectively to the adhesion molecule human P-selectin, and particularly to such compounds comprising a peptide with an amino acid sequence XA x...
25	7531512	Method of use of peptide antagonists of zonulin to prevent or delay the onset of diabetes A method for preventing or delaying the onset of autoimmune diseases is disclosed.
26	7531504	Pharmaceutical composition and method for inhibiting gastrointestinal inflammation Peptide antagonists of zonulin are disclosed, as well as methods for the use of the same. The peptide antagonists bind to the zonula occludens receptor, yet do not physiologically modulate the...
27	7528227	Histone H2A peptide derivatives and uses thereof Peptides derived from a segment of human histone H2A, the segment corresponding to amino acid residues 36-44 of human histone H2A, are capable of reducing or ameliorating the extent of injury...
28	7524926	Mucin hypersecretion inhibitors and methods of use Peptides are provided that comprise less than 24 amino acids. The peptides have an amino acid sequence selected from the group consisting of: (a) an amino acid sequence having from 4 to 23...
29	7521529	Differentially protected orthogonal lanthionine technology The present invention provides a method of synthesizing an intramolecularly bridged polypeptide comprising at least one intramolecular bridge. The present invention further provides a method of...
30	7521426	HIV-specific CTL inducing peptides and medicaments for preventing or treating AIDS comprising the peptides Peptides which can induce specific CTLs for HIV, DNAs encoding for the peptides and medicaments for preventing and/or treating HIV comprising the peptides are provided. According to the present...
31	7521415	Methods of intracellular peptide delivery Methods and kits for transporting heterologous compounds into cells, particularly mammalian cells, are disclosed. The method involves the pretreatment of the cell with a polycation, cationic...
32	7517855	Peptides which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, compositions and uses thereof The present invention relates generally to peptides, which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, methods of making peptides, which inhibit angiogenesis, cell...
33	7517854	Melanocortin receptor agonists Small cyclic peptides of the formula X1-X2-X3-X4-X5-X6-X7-R 1 comprising 7-12 amino acid residues are provided. Said peptides are MC4 receptor agonists, and thus useful in the treatment of obesity...
34	7517654	Peptide and a derivative thereof promoting cell adhesion and spreading The present invention relates to a peptide promoting cell adhesion and spreading, fragments, and derivatives thereof, more particularly, integrin-α3β1-dependent peptide in human laminin-5 α3...
35	7514408	β-secretase enzyme compositions and methods Disclosed is an active, isolated β-secretase enzyme in purified and recombinant form. This enzyme is implicated in the production of amyloid plaque components which accumulate in the brains of...
36	7507718	Polymyxin B analogs for LPS detoxification The invention relates to SAEP II peptide dimers that mimic polymyxin B i.a. in its ability to bind non-covalently the lipopolysaccharide (LPS) of Gram-negative bacteria with high affinity, and...
37	7504381	Antimicrobial agents A novel class of antimicrobial polymeric agents, which include a plurality of amino acid residues, such as positively charged amino acid residues, and at least one hydrophobic residue linking there...
38	7498306	Peptides binding to the phosphatase 2A protein The invention relates to novel synthetic or natural E4orf4 or Bcl-2 peptides particularly useful in antitumoral, antiviral and antiparasitic treatments, said peptides being less than 30 amino acids...
39	7491701	Peptides that bind to HSP90 proteins YSLPGYMVKKLLGA (SEQ ID NO:1) and its active analogs, compositions, and methods of use.
40	7491699	Peptide nanostructures and methods of generating and using the same A tubular or spherical nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids...
41	7491691	Connective tissue stimulating peptides Novel peptides are described which comprise an amino acid motif selected from the group consisting of “PG”, “GP”, “PI” and “IG” and having up to 10 amino acids upstream and/or...
42	7491690	Self-assembly and mineralization of peptide-amphiphile nanofibers Peptide-amphiphilic compositions capable of self-assembly into useful nanostructures.
43	7482429	Kahalalide F and related compounds A process is provided for preparing kahalalide F and which leads to other kahalalide mimic compounds having useful biological activity.
44	7479483	Tumor-targeted drug delivery systems and uses thereof The present invention relates to targeted delivery systems for delivering therapeutic agents to tumor. The invention further relates to methods of delivering a therapeutic agent to a tumor for the...
45	7476649	Antiproliferative and antiviral proteins and peptides The present invention relates to peptides and proteins which may be used to inhibit infection or cell proliferation. It is based, at least in part, on the discovery of peptides and proteins...
46	7473760	Cyclic peptide compositions for treatment of sexual dysfunction A cyclic peptide of the structural formula: or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 5 , R 6 , m, n and p are as defined. Further provided are compositions for...
47	7470658	Methods for inhibiting tumor metastasis, and peptides useful therefor In accordance with the present invention, there are provided peptides that bind to a member of the mammalian selectin family and inhibit the binding of a carbohydrate to the selectin. Invention...
48	7465709	Structural formulas based on the repetitive motifs of salivary proline rich proteins mucin and collagen designed to modulate cell and tissue growth division and differentiation Computational analysis was used to derive structural peptide formulas SALIVAR, SALIVAL, SALIVAN characterizing common repetitive fragments that reconstruct a large number of salivary proline rich...
49	7452868	Controlled release formulations of octreotide A formulation of octreotide or pharmaceutically acceptable salts thereof, which provides controlled release of a therapeutically effective amount of octreotide for a period of at least about two...
50	7452867	Use of ADNF polypeptides for treating peripheral neurotoxicity This invention relates to the use of ADNF polypeptides in the treatment of neurotoxicity induced by chemical agents or by disease processes. The ADNF polypeptides include ADNF I and ADNF III (also...

Matches 1 - 50 out of 799

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