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7347984 |
Mammalian agmatinase inhibitory substance
The present invention provides for methods and compounds for treating brain trauma and disorders such as: ischemia, stroke, neurodegenerative disorders, opioid addiction, idiopathic pain, epilepsy,...
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7320967 |
Cosmetic composition, method of cosmetic treatment and preparation of a composition for promoting the growth and/or preventing or delaying the loss of hair
The invention relates to a cosmetic composition containing at least one 15-hydroxy-prostaglandin dehydrogenase inhibitor and cosmetically acceptable excipients. It also relates to a method of...
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7001924 |
Inhibitors of RNase P proteins as antibacterial compounds
The present invention features compounds useful for inhibiting RNase P activity. These compounds can be used as therapeutics for treating or preventing a variety of bacterial infections. The...
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6777000 |
In-situ gel formation of pectin
In-situ gelation of a pectic substance. Composition, method of preparation, and method of use of a pectin in-situ gelling formulation for the delivery and sustained release of a physiologically...
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6573254 |
Method for the stimulation of sperm production and gonadal development in animals
Disclosed is a method to stimulate or enhance sperm development in males and gonadal development in females by administration of an agent which results in a transiently level of a thyroid hormone...
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6432935 |
Pharmaceutical compositions, mainly vaginal suppository, containing many different active ingredients
Compositions comprising an antibiotic, sulphonamide, at least one an antiquagul agent, e.g., clotrimazol (bis-phenyl-(2-chlorophenyl)-1-imidazolyl-methane), natamycin, or nystatin,and...
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6180633 |
Drug resistance and multidrug resistance modulators
Drug and multidrug resistant modulators of the formula: ##STR1## where R 1 and R 2 are independently hydrogen or halo; A is --CH 2 --CH 2 --, --CH 2 --CHR 4 --CH 2 --, or --CH 2 --CHR 5 ...
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5725875 |
Protective skin composition
A protective cream composition contains 15 to 40 wt % of an alkali metal fatty acid salt having from 8 to 18 carbon atoms, an effective amount of a topical agent such as an antimicrobial compound,...
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5370876 |
Antimicrobial protective skin composition and method for protecting skin from body fluids
A protective cream composition contains 15 to 40 wt. % of an alkali metal fatty acid salt having from 8 to 18 carbon atoms, an effective amount an antimicrobial compound, 5 to 20 wt. % of a polyol...
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5335675 |
Stress-softened elastomeric films, articles, and method and apparatus for making such films and articles
A stress-softened thermoplastic elastomeric (TPE) film which has been subjected to tensional deformation comprising at least uniaxial strain, and having improved textural and thermal transmissivity...
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5330980 |
Medicament for the topical treatment of skin
A medicament for the topical treatment of burned, irritated, ulcered, chafed, or infected, skin, a method of making the medicament, and a method of use of the medicament, the medicament comprising:...
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5273970 |
Treatment of protozoal diseases
The antibacterial substance baquiloprim (2,4-diamino-5-[8-dimethylamino-7-methyl-5-quinolylmethyl]py
rimidine) is shown to be active against protozoal infections, e.g. toxoplasmosis. Preferably the...
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5258373 |
Anticoccidial compositions
Compositions comprising a mixture of the antibiotic frenolicin B with a potentiated sulfonamide anticoccidial agent, useful for the treatment and prevention of coccidiosis in animals and methods of...
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5179127 |
Halopropargyl acyl compound, compositions, microbicidal uses and processes of preparation
Compounds of the formula ##STR1## wherein A is selected from the group consisting of (1) phenyl, (2) naphthyl, (3) phenyl substituted with one or more halo, cyano, (C 1 -C 4 )alkyl, nitro, (C 1 ...
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5135924 |
Therapeutic treatment of animals with oral administration of ormetoprim-potentiated sulfonamides
Systemic bacterial infections caused by aerobic and anaerobic organisms in companion animals such as dogs can be treated effectively and conveniently by the oral administration on a once a day...
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5096896 |
Sustained release compositions
A non-crosslinked derivative formable by reacting at least one substituted or unsubstituted, saturated or unsaturated, mono-, di- or poly-carboxy, hydroxy or mercapto hydrocarbon with at least one...
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5063219 |
Anticoccidial composition
Compositions comprising a mixture of a 2,4-diamino-5-(trisubstituted)benzyl-pyrimidine potentiated sulfonamide antibiotic with an ionophorous polyether anticoccidial agent are useful for the...
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4956354 |
Therapeutic preparation for use on skin
A therapeutic preparation for the treatment of skin problems. More particularly, the preparation is a mixture including almond oil, sulfathiazole, water and paraffin wax.
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4931433 |
Method for treating certain neoplastic diseases
Compounds of formula I are formulated with a pharmaceutical carrier for the treatment of neoplastic disease sensitive to treatment with the compounds in animals including humans. ##STR1## wherein:...
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4871722 |
Synergistic veterinary composition and/or fodder premix and process for preparing same
The invention relates to a synergistic veterinary composition and/or a fodder premix useful for preventing or curing bacterial, fungal and protozoic infection particularly occurring at poultry...
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4818753 |
Synthesis and method of use for 2, 4 diaminoquinazoline
Compounds of the formula ##STR1## wherein R 1 is H, methyl, ethyl, or chloro and R 2 is hydrocarbyl of 1-12 C are useful as antifungal agents. Compounds of this series wherein R 2 is 7-12 C are...
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4792551 |
9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents
Compounds useful for treating inflammation, pain and swelling, represented by the formula: ##STR1## and the pharmaceutically acceptable acid addition salts thereof, wherein: Y and Z are each...
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4781920 |
Anthelmintic paste compositions containing resinates of d1-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole
The invention provides physically stable anthelmintic paste compositions containing resinates of d1-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole and other anthelmintic compounds in combination...
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4735959 |
Carboxylic acid amides and pharmaceutical compositions containing them
There are described novel carboxylic acid derivatives of the formula ##STR1## and derivatives of the formula ##STR2## and the addition salts thereof, which exhibit an effect on the intermediary...
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4696921 |
Antimalarial pharmaceutical compositions
Mixtures of active substances and pharmaceutical compositions useful in malaria therapy comprising a quinolinemethanol derivative of the formula ##STR1## wherein R 1 is hydrogen, fluorine,...
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4677143 |
Antimicrobial compositions
Antimicrobial compositions finding particular utility for coating access systems, lead devices including shunts, cannulae, catheters, catheter adapters, wires and other solid or hollow tubular...
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4612337 |
Method for preparing infection-resistant materials
An infection-resistant polymeric material, such as polytetrafluoroethylene, for use on or within a human or animal body, for example, in the form of a vascular graft, can be prepared by an improved...
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4599226 |
Wound dressing comprising silver sulfadiazine incorporated in animal tissue and method of preparation
Animal tissue and the like having silver sulfadiazine incorporated therein is useful as a covering for burns and/or wounds. The silver sulfadiazine is incorporated in the tissue by soaking the...
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4581028 |
Infection-resistant materials and method of making same through use of sulfonamides
Infection-resistant materials, and methods of preparing same, suitable for use within the interior of a human or animal body in such forms as vascular grafts prostheses, or other implanted devices....
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4579731 |
Polymeric diffusion burn matrix and method of use
A protective skin matrix is provided which is particularly suited for the protection of burned or wounded patients. The matrix may be either cured, applied in sheets, or painted or sprayed directly...
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4562211 |
Pharmaceutically active 2-substituted-1-(omega-aminoalkoxy)benzenes
2-Substituted-1-(omega-aminoalkoxy)benzenes are prepared and found useful as pharmaceutical agents, particularly as antidepressants.
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4559223 |
Silver sulfadiazine and/or zinc sulfadiazine-containing toothpaste or oral medicament
This invention discloses compositions useful as dentifrices or oral medicaments and capable of inhibiting microbial mouth infections. The compositions contain an effectiveamount of silver and/or...
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4551464 |
Antithrombotic sulfoximino carbostyrils
Compounds of the formula ##STR1## wherein n is 0 or 1; A is methylene, vinylene or ethylene optionally substituted by lower alkyl; B is alkylene; R 1 is an optionally substituted alkyl,...
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4535078 |
Antibacterial composition comprising silver sulfadiazine and sodium piperacillin
An antibacterial composition useful in burn therapy comprises silver sulfadiazine, sodium piperacillin and a physiologically acceptable carrier.
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RE31926 |
Penicillins and salts thereof
Compounds of the formula ##STR1## wherein A is phenyl; 4-hydroxy-phenyl; 2- or 3-thienyl; cyclohexyl; cyclohexen-1-yl; cyclohexa-1, 4-dien-1-yl; or 3,4-disubstituted phenyl, where the substituents...
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4470978 |
Synergistic antibacterial composition
A composition is prepared of trimethoprim, an antibacterial sulfa drug or a pharmaceutically acceptable salt thereof, and phenoxyethanol in synergistically effective and antibacterial effective...
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4447421 |
Process for the preparation of medicated animal feed supplement
The invention is a process for the preparation of animal feed supplements containing various drugs or drug combinations, wherein uniformly potent particles of controlled particle size are obtained...
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4423043 |
Aqueous liquid formulations for control of bacterial and protozoal diseases
A stable aqueous formulation containing as active substance an active-substance combination consisting of 2,6-diamino-5-(3',4', 5'-trimethoxybenzyl)-pyrimidine (trimethoprim) and either...
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4415574 |
Soluble N.sub.2 substituted derivatives of 2,4-diamino 5-benzyl pyrimidine, process for their preparation and medicaments containing them
The present invention relates to novel soluble N 2 substituted derivatives of 2,4-diamino 5-benzyl pyrimidines. These derivatives correspond to the general formula III below: ##STR1## The novel...
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4404197 |
Antimicrobial compositions containing 1-ethyl-6-fluoro-1,4-dihydro-4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoli ne carboxylic acid or metal salts thereof and silver sulfadiazine
Compositions which include 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quino
line carboxylic acid or its metal salts, e.g., silver, zinc, cobalt or cerium salts, and silver sulfadiazine...
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4386084 |
N-Pyrimidinyl-carbamic acid esters, their preparation, and drugs containing these compounds
2-Carbamic acid esters of 2,4-diamino-5-(3',4',5'-trimethoxybenzyl)-pyrimidine (trimethoprim), a process for their preparation, and drugs containing these compounds, which, as pro-drugs of...
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4379784 |
Pyrimidinyl ureido penicillins
Compounds of the formula ##STR1## wherein A is phenyl, 4-hydroxy-phenyl, 2-thienyl or 3,4-dihydroxy-phenyl; and R is ##STR2## where R 1 and R 2 , which may be identical to or different from...
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4374826 |
Sulfonamide compositions
Aqueous parenteral solutions of from about 10 to 20% w/v of sulfamethoxazole or sulfadoxine and about 3 to 5% w/v of trimethoprim in from about 60 to 80% w/v of 2-pyrrolidone are disclosed.
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4347238 |
Autoclavable emulsion containing silver sulphadiazine
A mobile, drop-forming heat-sterilizable ophthalmic oil-in-water emulsion which comprises an aqueous solution of a pharmaceutically acceptable salt of polyacrylic acid lightly cross-linked with...
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4335119 |
Quick-acting diuretic compositions
A diuretically active pharmacological composition which comprises 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid (furosemide) together with at least one compound of formula (I) ##STR1## wherein R...
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4333936 |
Novel amidino-benzylpyrimidines, processes for their manufacture and antibacterial and antiprotozoal use thereof
5-Benzyl-4-amino-pyrimidine-2-amidines which may or may not be substituted in the phenyl ring, and their physiologically acceptable addition salts with acids, processes for their preparation, drugs...
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4332796 |
Potentiated sulfonamide injectable preparation
Potentiated sulfonamide compositions useful for intramuscular injection are disclosed which comprise mixtures of alkali metal sulfonamides with microcrystalline potentiators wherein the...
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4321257 |
Potentiated medicaments
Antimicrobial compositions are provided wherein there is obtained an enhancement of the activity of an antimicrobial agent exemplified by quarternary ammonium compounds, bisdiguanides, anti-fungal...
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4315931 |
N-Pyrimidinyl-imidoacid esters and drugs containing the said compounds
Unsubstituted or substituted 5-phenyl- and 5-benzyl-4-amino-pyrimidine-2-imidoacid esters, their preparation, drugs containing these compounds, and their use in infectious diseases.
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4315932 |
Method of using 1H-pyrimido-4,5-c -1,2-diazepines as antibacterial and anticoccidocidal agents
Compounds of the general formula (I) ##STR1## wherein R 1 and R 2 are selected from a lower alkyl group, a phenyl group (optionally substituted by one or more hydroxy or lower alkoxy groups), a...
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