|
Match
|
Document |
Document Title |
|
|
6482800 |
Methods to stimulate angiogenesis
The present invention provides methods and kits for increasing blood flow to isehemic tissue, comprising the administration of an effective amount of angiotensinogen, angiotensin I (AI), AI...
|
|
|
6479063 |
Therapeutic uses of hormonal manipulation using combinations of various agents to treat atherosclerosis
A method of decreasing atherosclerosis and its complications involving administering to a human or animal various combinations of medications with Finasteride, Bicalutamide, Flutamide and Nilutamide.
|
|
|
6475988 |
Methods to increase white blood cell survival after chemotherapy
The present invention provides improved methods, kits, and pharmaceutical compositions for increasing white blood cell survival following chemotherapy, and mobilizing hematopoietic progenitor cells...
|
|
|
6468972 |
Method to promote, stimulate and/or delay hair loss by a brady kinin antagonist
The present invention is directed to a method to promote, stimulate and/or delay hair loss by administering an effective amount of at least one bradykinin antagonists to promote, stimulate and/or...
|
|
|
6468971 |
Maintaining kidney function during surgery or trauma
Kappa-opioid agonists prevent the impairment of renal function otherwise caused by the combination of gaseous anesthesia and surgery or severe trauma. Not only do these agents preserve renal...
|
|
|
6468973 |
Method in the treatment of schizophrenia
The invention relates to the use of a composition comprising at least one substance within the group GnRH-analogues for producing a drug for treatment of schizophrenia. The invention makes it...
|
|
|
6468969 |
Inhibition of HIV-1 replication using d-amino acid peptides
The Tat-inhibitory polypeptide derivatives of the formula I ...
|
|
|
6465432 |
Isolated antioxidant peptides form casein and methods for preparing, isolating, and identifying antioxidant peptides
The current invention provides antioxidative peptide fractions. The invention includes antioxidative peptides of casein having sequences of SEQ ID NOS:1-5. The invention includes methods for making...
|
|
|
6465430 |
Peptides and compounds that bind to a thrombopoietin receptor
Receptors are peptides and peptide mimetics that bind to and activate the thrombopoietin receptor. Such peptides and peptide mimetics are useful in methods for treating hematological disorders and...
|
|
|
6464980 |
MAGE-1 c-terminal immunogenic peptides
The complete nucleotide and amino acid sequences of the human MAGE-1 antigen are provided. Peptides from residues of the C-terminal are used to define epitopes that stimulate HLA-restricted...
|
|
|
6455499 |
Methods for treating disorders associated with LHRH activity
Methods of treating a subject having a disorder associated with LHRH activity are disclosed.
|
|
|
6447775 |
Modulators of expression and function of LRP in Alzheimer's disease
The present invention relates to methods and compositions for preventing the endocytosis and cellular internalization of integral membrane amyloid β-precursor protein (APP) and its subsequent...
|
|
|
6444644 |
Anticoagulant peptide fragments derived from apolipoprotein B-100
The present invention provides a peptide compound of formula Z 1 —K—A—Q—X 1 —K—K—N—K—H—R—H—S—X 2 —T—Z 2 (SEQ ID NO:1) where: X 1 represents S or Y, X 2 represents T...
|
|
|
6444645 |
Crosslink-stabilized indolicidin analogs
The present invention relates to crosslink-stabilized analogs of indolicidin, which is a naturally occurring peptide having the amino acid sequence...
|
|
|
6436903 |
Immunomodulating compounds comprising d-isomers of amino acids
Compounds having immunomodulatory activity which are peptide-type compounds, or variants or fragments thereof, including the N-terminal acylated and C-terminal amidated or esterified forms of up to...
|
|
|
6432405 |
Method of inhibiting HIV infection with CD44 and anti-CD44 antibodies
The present invention relates to a method of inhibiting HIV infection of cells susceptible to HIV infection. The method comprises contacting such cells with an agent (such as an anti-CD44 antibody)...
|
|
|
6432920 |
Nck SH3 binding peptides
Peptides having general and specific binding affinities for the Src homology region 3 (SH3) domains of proteins are disclosed in the present invention. In particular, SH3 binding peptides have been...
|
|
|
6426330 |
Satiety inducing composition comprising Neuropeptide Y analogues and methods of inducing satiety and treating a disease or condition associated with it
Satiety inducing composition comprises Neuropeptide Y analogues which are effective for inducing satiety and for treating diseases and conditions associated with a lacking of, or having lowered,...
|
|
|
6423719 |
Method for treating benign prostate hyperplasia
A method of treating and/or preventing renal dysfunction in a patient, such as renal colic or contrast nephropathy by administering to a patient, a compound of the formula: is described herein....
|
|
|
6423315 |
Synthetic peptide for treatment of autoimmune arthritis
Peptides that are capable of suppressing autoimmune arthritis are disclosed. The polypeptides described by the present invention which are capable of suppressing autoimmune arthritis in mammals...
|
|
|
6417159 |
Method of enhancing effect of a neurotrophin with analogues of p75NTR367-379.
The present invention provides methods and compositions for enhancing the effect of a neurotrophin on a cell expressing a neurotrophin receptor. The effect is preferably neurotrophin-mediated...
|
|
|
6417165 |
NY-ESO-1-peptide derivatives, and uses thereof
The invention relates to variant peptides which bind to HLA molecules, leading to lysis of cells via cytolytic T cell lines. The variants are based upon NY-ESO-1 peptides. The peptides can be...
|
|
|
6413517 |
Identification of broadly reactive DR restricted epitopes
The present invention is based on peptide binding specificities of HLA DR4w4, DR1 and DR7. Peptides binding to these DR molecules have a motif characterized by a large aromatic or hydrophobic...
|
|
|
6413516 |
Peptides and methods against psoriasis
This invention relates to methods of preventing or reducing the severity of psoriasis. In one embodiment, the method involves administering to the individual a peptide having substantially the...
|
|
|
6407063 |
Tumor antigens and CTL clones isolated by a novel procedure
The present invention relates to isolation of cytotoxic T lymphocyte (CTL) clones. In particular, the present invention relates to isolated CTL clones that are specific for MAGE-1 and MAGE-4,...
|
|
|
6403553 |
Use of polypeptides for treating thrombocytopenia
The present invention relates to the use of polypeptides of the MIP (macrophage inflammatory proteins) class for the treatment of diseases involving a pathological change of thrombocytopolesis,...
|
|
|
6391305 |
Conjugates useful in the treatment of prostate cancer
Chemical conjugates which comprise oligopeptides, having amino acid sequences that are selectively proteolytically cleaved by free prostate specific antigen (PSA), hydrophilic oligopeptide blocking...
|
|
|
6391855 |
Compounds and methods for modulating junctional adhesion molecule-mediated functions
Methods for using modulating agents to enhance or inhibit junctional adhesion molecule (JAM)-mediated cell adhesion in a variety of in vivo and in vitro contexts are provided. The modulating agents...
|
|
|
6384017 |
Methods for treating sex hormone-dependent conditions with Lhrh antagonists
Methods for treating prostate cancer are disclosed. The methods of the invention generally feature administration to a subject of an LHRH-R antagonist, in combination with a second therapy. In one...
|
|
|
6380161 |
Compositions for treating chemotherapy-resistant tumor cells and targeted chemotherapy compositions
The present invention provides methods and compositions for treating cancer and chemotherapy-resistant cancers comprising a chemotherapeutic agent conjugated to or coadministered with a peptide.
|
|
|
6380157 |
Method of treatment using papillomavirus L2 protein
The L2 protein of papillomavirus (particularly BPV-2 and BPV-4) has been cloned as a fusion protein with beta-galactosidase and GST; both as the whole protein and as fragments. Vaccination of...
|
|
|
6368852 |
Peptide capable of inducing immune response to human gastric cancer and agent for preventing or treating human gastric cancer, containing the peptide
A peptide that induces CTL against human gastric cancer cells is provided. A peptide having a specific amino-acid sequence and induces cytotoxic T cells that targets gastric cancer cells may be...
|
|
|
6369030 |
Inhibitors of histone acetyltransferases (HATs) and uses thereof
Histone acetyltransferase inhibitors, especially those that are differentiate between p300 and PCAF histone acetyltransferase; also therapeutic processes comprising their administration to humans.
|
|
|
6365124 |
Compositions for detecting and surgically removing lymphoid tissue involved in tumor progression
Compositions are provided for detecting Tn antigen expressing-shed tumor antigen. The compositions include peptides having binding specificity for the Tn antigen; and a detector molecule comprising...
|
|
|
6358915 |
Methods for inhibiting metastasis
The invention relates to methods for determining degree of integrin-mediated maintenance of cell invasive capacity of tumors, and to methods and compositions for inhibiting or preventing metastasis...
|
|
|
6358927 |
Peptide fragments and analogs derived from PBAN 1-33 NH2 for controlling moths
Synthetic peptide fragments from pheromone biosynthesis activating neuropeptide PBAN (1-33)-NH 2 of Helicoverpa zea which have either pheromone biosynthesis stimulating or inhibiting activity.
|
|
|
6358928 |
Peptidyl sulfonyl imidazolides as selective inhibitors of serine proteases
Novel α-amino and peptidyl sulfonyl imidazolides, a method for their synthesis, and a method for inhibiting serine proteases therewith are disclosed. Pharmaceutical compositions containing...
|
|
|
6355616 |
Derivative compounds derived from or based on bactericidal/permeability-increasing protein
The present invention relates generally to derivatized antifungal compounds that are peptide-based constructs derived from or based on subsequences of Domain III (amino acids 142-169) of...
|
|
|
6355617 |
Peptide derivatives
The invention concerns pharmaceutically useful peptide derivatives of the formula (I): P—R 1 —R 2 —R 3 —R 4 , in which P, R 1 , R 2 , R 3 and R 4 have various meanings defined herein, and...
|
|
|
6355619 |
Peptide tumor cell growth inhibitors
Disclosed are peptide-based compositions and methods for inhibiting and modulating the actions of CXC intercrine molecules. The antileukinate peptides described inhibit IL-8, GRO and MIP2β binding...
|
|
|
6350731 |
Platelet-derived growth factor analogues
Novel peptide analogues of platelet-derived growth factor, for use in inhibiting or stimulating growth and/or chemotaxis of cells, for example, smooth muscle cells, are provided. Also provided are...
|
|
|
6346514 |
Pharmaceutical lysine-containing polypeptide compositions and methods of use thereof
Pharmaceutical compositions and methods are provided for the therapy of immunodeficient, immunodepressed or hyperactive immune states and for the prevention and treatment of opportunistic...
|
|
|
6344442 |
Zona pellucida proteins for contraception
The present invention relates to the use of peptides which are derived from zona pellucida proteins and are used for contraception, and pharmaceutical formulations which contain the peptides...
|
|
|
6342479 |
Prolonging survival of transplanted pancreatic cells
A method of prolonging the survival of pancreatic cells transplanted in a patient. The method includes the step of administering a therapeutically effective amount of somatostatin or a somatostatin...
|
|
|
6342218 |
Method for treatment of SLE
Treatments have been developed for lupus patients using either anti-ID antibodies to dsDNA to block anti-dsDNA antibodies and/or kill the B cells producing the anti-dsDNA antibodies or ribosomal...
|
|
|
6338946 |
Method for assaying immunosuppressant
This invention relates to a method and kit for assaying an immunosuppressant having a calcineurin-inhibiting activity by assaying a complex containing immunophilin, calcineurin, calmodulin, calcium...
|
|
|
6339062 |
Retroinverso polypeptides that mimic or inhibit thrombospondin activity
The present invention relates generally to polypeptides that mimic or inhibit the biological activity of thrombospondin, and particularly to polypeptides in retroinverso form. These polypeptides...
|
|
|
6337318 |
Sustained GnRH peptide-release formulation
A pharmaceutical and/or veterinary formulation for sustained release of a peptide agonist or analogue, comprising about 2-15% (w/w) of at least one peptide agonist or analogue other than deslorelin...
|
|
|
6337316 |
Pharmaceutical compositions thereof, and methods of using same
The present invention relates to peptidomimetics capable of inhibiting CD28 and/or CTLA-4 interaction with CD80 (B7-1) and CD86 (B7-2) and having a core amino acid sequence,...
|
|
|
6333042 |
Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained
A substance P antagonist is used in a cosmetic composition to treat sensitive skin. More specifically, a cosmetic composition containing a substance P antagonist is used to prevent and/or combat...
|