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7507851 |
Halocombstatins and methods of synthesis thereof
The invention relates to novel compounds denominated halocombstatins. The halocombstatins are derivatives of combretastatin A-3, and include compounds that exhibit cancer growth cell inhibition...
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7479507 |
Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs
3,5-di-substituted-4-hydroxybenzylidene phosphonates and sulfonates useful in treating inflammatory disease, particularly osteoarthritis, and elastomeric particles for oral delivery of drugs are...
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7354966 |
Compounds for use as surfactants
Compounds of formula (I):
and uses of such compounds are described.
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7354912 |
Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced GI toxicity
Compositions and methods for treating osteoporosis using the compositions are disclosed where the compositions have reduced GI toxicity and improved bio-availability and include a bisphosphonate...
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7288278 |
Process for preparing vegetable oil fractions rich in non-tocolic, high-melting, unsaponifiable matter
A vegetable oil fraction rich in non-tocolic, high-melting, unsaponifiable matter is prepared by the following steps: A vegetable oil having a slip melting point of not more thatn 30° C. and a...
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7252706 |
Inhibition of calcium and magnesium precipitation from wood preservatives
A wood preservative that contains a copper salt complex and a precipitation inhibitor is provided. The wood preservative may contain copper carbonate, an alkanolamine such as monoethanolamine and...
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7173049 |
Fungicidal compositions
1) Fungicidal compositions comprising:
a) at least one pyridylmethylbenzamide derivative of formula (I):
in which the various radicals are as defined in the description,...
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7147872 |
Environmentally compatible processes compositions and materials treated thereby
Environmentally friendly processes for prevention of qualitative deterioration and quantitative loss of plant matter and foodstuffs, during all stages of storage and handling, including pre- and...
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7101907 |
Topical administration of statins for treatment of bone disorders
The topical administration of statins for the treatment of bone disorders is disclosed.
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7052707 |
Pharmaceutical composition containing aminoacetonitril compounds and the use thereof for the preparation of a pharmaceutical composition for the treatment of endoparasitic pests in animals
The invention relates to a composition for controlling a pest, including endoparasites, and more specifically helminths, of formula (I)
in animals, and methods related to thereof.
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7011854 |
Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof
Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g., rheumatoid arthritis, and of diseases...
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6964952 |
Therapeutic composition for broad spectrum dermal disease
The invention relates to a therapeutic composition for broad spectrum dermal disease and in particular, to a composition comprising principal lipid components of skin, preferably having about 30 to...
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6919322 |
Phenyl Phosphonate Fructose-1,6-Bisphosphatase Inhibitors
Novel FBPase inhibitors of the formula I
are useful in the treatment of diabetes and other conditions associated with elevated blood glucose.
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6803057 |
Hydrogen peroxide disinfectant with increased activity
An acidic aqueous hydrogen peroxide solution is provided with improved disinfectant activity. Concentrated solutions preferably contain up to about 8 wt./wt. % H2O2 and as-used concentrations...
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6706290 |
Methods for eradication of nanobacteria
Nanobacteria contribute to pathological calcification in the human and animal body, including diseases such as kidney stones, salivary gland stones, dental pulp stones and atherosclerosis. The...
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6689392 |
Methods and compositions for controlling plant pathogen
A composition for controlling growth of pathological organisms on a plant, said composition comprises an effective amount of one or more of metal ion(s); one or more of chelating agent(s); and...
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6673358 |
Wet wipes containing a mono alkyl phosphate
Wet wipes impregnated with a solution which includes a mono alkyl phosphate are described. In particular, the solution in the wet wipes includes a phosphate ester surfactant which includes a mono...
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6649646 |
Insecticidal and miticidal compositions
The invention relates to an insecticidal and miticidal composition which contains as active ingredients chlorfenapyr in combination with one or more organophosphoric acid ester-type compounds and...
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6645962 |
Process of using prodigiosin as an immunosuppressive
There are disclosed a novel microorganism Serratia marcescens strain and a prodigiosin isolated from the microorganism. The prodigiosin is useful as an immunosuppressive in various fields,...
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6627660 |
Stabilized thyroxine compounds
Throxinyldimethylphosphinate was invented as a prodrug to stabilize thyroxine, a drug widely used to treat hypothyroidism. The presence of the dimethylphosphinate group at the phenolic hydroxyl of...
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6566304 |
Biogenic control and limitation of the reproduction of parasitic earth nematodes in stock culture
The invention relates to use of (a) compounds of phosphorus containing at least partly lipophilic organic radicals together with (b) urea and/or urea derivatives in selected quantity ratios of (a)...
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6565892 |
Synergistic fungicidal composition comprising a compound analogous to strobilurin
Synergistic fungicidal composition comprising a compound analogous to strobilurin of formula (I): in which: A is the nitrogen atom or the —CH group, B is the —OCH 2 — or —CH 2 O— or...
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6518260 |
(α-aminophosphino) peptide derivatives, method for making same and therapeutic applications thereof
The invention concerns compounds derived from (α-aminophosphino) peptides, of general formula (I), in which R 1 and R 2 each represents a hydrogen atom or taken together form an imine with the...
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6506739 |
Bis-(N,N'-bis-(2-haloethyl)amino)phosphoramidates as antitumor agents
Bis-(N,N′-bis-(2-haloethyl)amino)phosphoramidates, pharmaceutical compositions containing them, methods of treatment using them, and processes for their preparation. The compounds possess...
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6498151 |
Aryldifluoromethylphosphonic acids with sulfur-containing substituents as PTP-1B inhibitors
The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions and...
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6448240 |
Synergistic fungicidal and/or bactericidal composition
The invention concerns a synergetic fungicide and/or bactericide composition comprising famoxadone and a phosphorous acid derivative; and a method for fighting, for cure or prevention, against...
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6416737 |
Increasing bone strength with selected bisphosphonates
The present invention is a method and composition to increase bone strength in a manner that decreases fracture incidence, which may or may not include increasing bone mineral density (“BMD”)....
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6391369 |
Selectively hydrogenated high oleic oil compositions and process
Butters are made from high oleic vegetable oils during a procedure by which a large percentage of the oleic acid is transformed into trans-configured elaidic acid, without significantly increasing...
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6380177 |
LPA analogs as agonists of the Edg2 LPA receptor
Applicant has probed the Edg2 lysophosphatidic acid (LPA) receptor with a series of LPA analogs to determine receptor activation. The present invention is drawn to a series of LPA analogs which...
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6358938 |
Synergistic fungicidal composition
Synergistic fungicidal composition comprising propamocarb and a derivative of phosphorous acid; and process for the curative or preventative control of phytopathogenic fungi by use of such a...
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6358941 |
Treatment of arthritis disorders, rheumatoid arthritis and manifestations associated with rheumatoid disorders
The present invention relates to the use of pharmaceutically acceptable cholinesterase inhibitors for the preparation of a pharmaceutical composition for the treatment or prophylaxis of arthritic...
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6200961 |
Concentrates of organophosphorous insecticides
A low volatile organic compound co-solvent system is disclosed for preparing emulsion concentrates of low melting organophosphorous insecticides wherein the bioefficacy of the insecticide active is...
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6136798 |
Compounds inhibiting the association of the PDGF receptor and phosphatidylinositol 3-kinase and their use
The present invention provides compounds that inhibit the association of platelet-derived growth factor and phosphatidylinositol 3-kinase. The present invention also provides pharmaceutical...
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6114340 |
Fungicidal compositions
An improved fungicidal composition is a mixture of (a) fungicide used to combat phytopathogenic fungi and (b) at least one phosphonate or phosphinate of formula R 1 R 2 P(O)OR 3 where R 1 is C...
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6080779 |
Compositions and methods for stimulating bone growth
Compounds of the formula ##STR1## wherein X in each of formulas (1) and (2) represents a substituted or unsubstituted alkylene, alkenylene, or alkynylene linker of 2-6 C; Y represents one or more...
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6071941 |
Protection of trees
A method for the protection of trees of the families Musaceae or Plantanginaceae from destructive pests whereby the trees to be protected share a common root system.
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6034117 |
Methods of treating and diagnosing sleep disordered breathing and means for carrying out the method
This invention relates to a method for treating snoring, sleep apnea and other form of sleep-disordered breathing, which comprises administration of a therapeutically effective dose of an acetyl...
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6017910 |
PCP receptor ligands and the use thereof
The invention relates to 5-(iminomethano)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene and derivatives thereof. The invention also relates to the use of such compounds for the treatment or prevention...
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6013642 |
Use of estrone derivatives as steroid sulphatase inhibitors
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5997910 |
Plant fertilizer compositions containing phosphonate and phosphate salts and derivatives thereof
A fertilizer composition for plants containing phosphonate and phosphate slats, and derivatives thereof is disclosed. The composition provides a single product which may be employed to stimulate...
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5998391 |
Microbicidal composition
There is disclosed a microbicidal composition comprising as active ingredients: (I) a dithiocarbonimide compound represented by the general formula: ##STR1## wherein Z represents CH group or...
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5994342 |
3-(substituted methyl)-4-oxa-1-azabicyclo[3.2.0]heptan-7-one derivatives useful as antitumor agents
The present invention is based on the discovery that certain 3-(substituted methyl)-4-oxa-1-azabicyclo[3.2.0]heptan-7-one derivatives of formula I or a pharmaceutically acceptable salt thereof are...
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5990098 |
Therapeutic use of 1-amino-3-(N,N-dimethylamino)-propylidene-1,1-bisphosphonic acid and its salts
Use of 1-amino-3-N,N-dimethylamino)-propyliden-1,1-bisphosphonic acid of the structural formula: ##STR1## or of its monosodium or other pharmaceutically acceptable salt, as a biological carrier for...
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5981515 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST*** Method for improving fruit yields from banana plants
Method for improving the fruit yields from banana plants, characterized in that an effective and non-phytotoxic dose of a compound A, chosen from: salts of a monoalkyl phosphonate and of a...
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5972942 |
Inhibitors of farnesyl-protein transferase
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to...
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5969017 |
Methods of treating or preventing cardiac arrhythmia
This application discloses a method of treating or preventing atrial arrhythmias which utilizes compounds which are blockers of the ultra-rapidly-activating delayed rectifier K + current (I Kur )...
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5951748 |
Compositions and methods for inhibiting fouling of vinyl monomers
Methods and compositions for inhibiting fouling in vinyl monomers are disclosed. Alkylphosphonate esters or acids thereof are added to vinyl monomers, particularly ethylene dichloride, that are...
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5925383 |
Fungicidal compositions for plants containing phosphonate and phosphate salts, and derivatives thereof
A fungicidal composition for plants containing phosphonate and phosphate salts, and derivatives thereof is disclosed. The composition provides a single product which may be employed to control a...
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5858996 |
Compositions and methods for stabilizing polymers
Compositions and methods for reducing the decomposition rate of polymeric bioadhesives and viscosity enhancers, such as poly(acrylic acids). The compositions include at least one strong, stable...
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5811419 |
Isooxacephem-derivatives
Compounds of formula I ##STR1## wherein R 1 is hydrogen or an acyl group derived from a carboxylic acid; R 2 is hydrogen, hydroxy, lower alkyl, cycloalkyl, lower alkoxy, lower alkenyl,...
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