Patents in Class 514/134

Matches 1 - 50 out of 89

1 2 >

Match	Document	Document Title
1	8017596	Phosphonates useful as modulators of T-γ-9-δ-2 activity The invention concerns novel phosphonate derivatives, preparation method, use thereof as ligands modulating T γ9δ2 lymphocyte activity and pharmaceutical compositions comprising them.
2	7723287	Treatment of the eye with a pharmaceutical composition A pharmaceutical composition for the treatment of disorders of the anterior segment of the eye or for the preservation of isolated cornea. The composition comprises, as an active ingredient, an...
3	7517869	Fluorophosphonocinnamic compounds, synthesis and uses for treating disorders caused by oxidative stress Process for the specific fluorination of the phosphorus atom of a phosphonocinnamic compound of the general formula (II) or (II′): X being selected from: an oxygen atom, a sulfur atom,R1, R2, R3, R...
4	7084126	Methods and compositions for enhancing cellular function through protection of tissue components Methods and composisions for enhancing cellular function through protection of a tissue components such receptors, proteins, lipids, nucleic acids, carbohydrates, hormones, vitamins, and cofactors,...
5	6919322	Phenyl Phosphonate Fructose-1,6-Bisphosphatase Inhibitors Novel FBPase inhibitors of the formula I are useful in the treatment of diabetes and other conditions associated with elevated blood glucose.
6	6566304	Biogenic control and limitation of the reproduction of parasitic earth nematodes in stock culture The invention relates to use of (a) compounds of phosphorus containing at least partly lipophilic organic radicals together with (b) urea and/or urea derivatives in selected quantity ratios of (a)...
7	6562804	Hair-growing agent The present invention provides a hair-growing agent comprising, as an active ingredient, a phosphatidic acid represented by formula (I): (wherein R1 represents alkyl, alkenyl, alkanoyl or alkenoyl;...
8	6525035	Therapeutic composition and methods The invention provides composition comprising, 1) polyprenol monophosphates of the formula H—[—CH2-C(CH3)═CH—CH2]n-O—P(═O)(OH)2 wherein n is an integer from 6-19 inclusive or a salt thereof, an...
9	6506737	Antimicrobial phosphonium and sulfonium polyhalide compositions An oxidizing species is described herein as a reaction product through an in situ preparation combining a protonizable phosphorus or sulfur compound, and a halide source at controlled proportions...
10	6242433	Geranylgeranyl-derivatives, process for the preparation thereof and related pharmaceutical compositions The present invention relates to novel geranylgeranyl derivatives and the pharmaceutically acceptable salts thereof having antiproliferative activity in eukaryotic cells with respect to the...
11	6184214	Pharmaceutical formulations A pharmaceutical composition is provided comprising an effective amount of a phosphoenolpyruvate compound of the formula: ##STR1##wherein R1 and R2 are independently H, alky, alkenyl, alkoxy...
12	6096330	Alkylphosphines as pesticidal agents A method for controlling pests comprising administering to them a compound of the formula (i) R-PH-R', wherein R is a C1 -C6 aliphatic hydrocarbyl group and R' is H or a C1 -C6 aliphatic...
13	5709890	Polyaspartic acid and its analogues in combination with insecticides An insecticide composition is enhanced from the standpoint of its ability to be absorbed by insects, such as red fire ants, particularly dithiophosphate ester pesticides by the addition of a small...
14	5648349	PLA2 inhibitors PLA2 inhibitors selected from the group consisting of ##STR1## wherein A is selected from the group consisting of ##STR2## and Z, W, R1, R2, R3, R4, R5, R6, R7, R8, R9, X, X' and Y are as defined...
15	5574025	Inhibitors of prenyl-protein transferases The compounds disclosed inhibit the prenylation of several proteins. These compounds are potent inhibitors of famesyl-protein transferase and geranylgeranyl-protein transferase. Further contained...
16	5541221	Pharmaceutical compositions and method for administering 3 and 4-substituted 2(5H)-furanones to a mammal for inhibiting bone loss 3 and 4-substituted 2(5H)-furanone compounds influence the balance between bone production and bone resorption in mammals, including humans. The active compounds are administered to mammals,...
17	5532226	Trifluoromethybenzylphosphonates useful in treating osteoporosis Novel benzylphosphonate compounds of the general formula I: ##STR1## are disclosed as useful in treating bone wasting diseases including postmenopausal osteoporosis in increasing in mammals bone...
18	5480877	Use of lysophosphatidic acids to enhance fibronectin binding Lysophosphatidic acids are used to enhance fibronectin binding. This assists in the process of wound healing. The acids are exogenously supplied. In one aspect, a kit is provided containing a skin...
19	5366727	Antibacterial agent An antibacterial agent comprising as an active ingredient a vinylbenzyl phosphonium salt of the general formula (I), ##STR1## wherein R1, R2 and R3 each represent a hydrogen atom, a linear or...
20	5306714	(S)-2,3-dihydropolyprenyl, monophosphate, and agents for inhibiting the metastasis of cancers Disclosed are (S)-2,3-dihydropolyprenol of formula (I) ##STR1## wherein m is 7 or 8 and (S)-2,3-dihydropolyprenyl monophosphate of formula (II) ##STR2## wherein m is 7 or 8 as well as...
21	5242908	Use of benzylphosphonic acid derivatives for the treatment of diseases caused by viruses The use of a compound of the formula I ##STR1## in which V is an alkyl group, fluorine, chlorine, bromine, or iodine, n is an integer from 1 to 5, W is an alkyl, alkenyl, alkynyl or alkoxy group,...
22	5186947	Wood preservative based on polymeric nitrogen compounds and metal-fixing acids Water-soluble wood preservatives which contain mixtures of a metal compound, a metal-fixing acid and a complexing polymeric nitrogen compound, and methods for protecting wood with such mixtures.
23	5147867	Phosphorus containing enzyme inhibitors Dipeptide mimics which contain phosphorus and their pharmaceutical use and preparation are disclosed. The compounds have dehydropeptidase (DHP) enzyme inhibitor activity.
24	5128333	Alkyl substituted phosphates and phosphonates as disruptants of insect sex pheromone-mediated behavior Compounds of the general formula I ##STR1## wherein R1 represents --R3, --OR3 or --N(R3)2, in which R3 is alkyl of 1 to about 18 carbon atoms; R2 represents alkyl of 1 to about 18 carbon atoms; and...
25	5015635	Pesticidal S-(halogenoalkyl)-dithiophosphoric(phosphonic) acid esters Pesticidal S-(halogenoalkyl)-dithiophosphoric (phosphonic) acid esters of the formula ##STR1## in which R1 represents an optionally substituted radical from the group consisting of alkyl, alkenyl,...
26	5004735	Pharmaceutical compositions for the inhibition of tumor metastasis Polyprenols and polyprenyl phosphates are of the formula ##STR1## wherein ##STR2## represents a trans-isoprene unit, ##STR3## represents a cis-isoprene unit, ##STR4## represents a dihydroisoprene...
27	4962097	Method of treating bacterial infection with phosphorus containing DHP enzyme inhibitors Dipeptide mimics which contain phosphorus and their pharmaceutical use and preparation are disclosed. The compounds have dehydropeptidase (DHP) enzyme inhibitor activity.
28	4946834	Phosphonic acid substituted steroids as steroid 5α-reductase inhibitors Invented are substituted acrylate analogues of steroidal synthetic compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid...
29	4920108	Bisthiolphosphates as pesticides Bisthiophosphates of the general formula ##STR1## where R1 is ethyl or isopropyl and R2 is branched or straight-chain C1 -C4 -alkyl, and their use for combating pests.
30	4851217	All aqueous formulations of organo-phosphorous pesticides A composition of matter and method of making the composition which relates to an all aqueous, phase stable emulsion of organophosphorous pesticides which is free of organic solvents. The...
31	4791105	Therapeutic and preventive agent containing dolichol Dolichol or phosphate thereof is useful as a therapeutically treating and preventive agent, in particular, for hyperuricuria, hyperlipemia, diabetes and hepatic diseases.
32	4659702	S-(substituted allylic) trithiophosphonate insecticides Compounds and compositions containing them, for insecticidal control, particularly for use as soil and/or foliar insecticides, have the formula ##STR1## in which R1 is C1 -C3 alkyl; R2 is C1 -C6...
33	4659703	S-allyl trithiophosphonate insecticides Insecticides have the formula ##STR1## in which R1 methyl or ethyl and R2 is C3 -C5 alkyl.
34	4656164	O-(substituted allylic) dithiophosphonate insecticides Compounds having the formula ##STR1## in which R1 is methyl or ethyl; R2 is C1 -C6 alkyl; R3 is hydrogen, halogen or methyl; and R4 is hydrogen, methyl or phenyl; or R3 and R4 taken together form a...
35	4613593	Therapeutic and preventive agent containing dolichol Dolichol or phosphate thereof is useful as a therapeutically treating and preventive agent, in particular, for hyperuricuria, hyperlipemia, diabetes and hepatic diseases.
36	4607026	Cyclopropane thiocarboxylic esters and insecticidal and acaricidal use thereof This invention relates to stereoisomeric forms and mixtures thereof of compounds of the formula ##STR1## having insecticidal, nematocidal, and acaricidal properties.
37	4588723	Aminoalkyl-imidazothiadiazole-alkenecarboxylic acid amides, intermediates for their preparation and their use in medicaments The invention relates to aminoalkyl-imidazothiadiazole-alkenecarboxylic acid amides, processes for their preparation, intermediates which are used in their preparation, medicaments containing said...
38	4582825	2-(substituted phenyl)-3-chloro-2-butene thio phosphates as insecticides Phosphates of the formula ##STR1## where R1 is alkyl of not more than 3 carbon atoms, R2 is alkoxy, alkylthio or alkylamino each of which has a straight-chain or branched alkyl substituent of not...
39	4576935	Dihalovinylphenyl phosphates and their use as pesticides Dihalovinylphenyl phosphates of the formula I ##STR1## where A and B are each halogen or trihaloalkyl, X is oxygen or sulfur, Y and Z are each oxygen, sulfur or --NH--, R1 is alkyl, R2 is alkyl,...
40	4567170	3-Chloro-3-phenylprop-2-enyl thiophosphates and their use for controlling pests Thiophosphates of the formula I ##STR1## where R1 is hydrogen, or not more than 4 identical or different substituents R1 may be present, each of which is fluorine, chlorine or bromine,...
41	4532343	Aromatic retinoic acid analogues Aromatic retinoic acid analogues of the formula ##STR1## where X is hydrogen or fluorine, Y is hydrogen, halogen of atomic number 9 or 17, hydroxy, alkyl of 1 to 2 carbon atoms or alkoxy of 1 to 2...
42	4390529	S-(Tertiary alkyl) alkylphosphonoamidodithioates and their use as insecticides and nematocides Compounds having the formula ##STR1## in which R is an alkyl of 1 to 8 carbon atoms, haloalkyl of 1 to 8 carbon atoms, alkenyl of 2 to 8 carbon atoms, haloalkenyl of 2 to 8 carbon atoms, alkynyl of...
43	4251522	Phenoxybenzylphosphonium salts and derivatives thereof and use as fungicides The fungicidal compounds having the formula: ##STR1## wherein A.crclbar. is a halogen anion; X, Y and Z are each independently hydrogen, a halogen atom or a haloalkyl radical of from 1 to 4 carbon...
44	4234576	Phenoxybenzylphosphonium salt pesticides The pesticidal compounds having the formula: ##STR1## wherein A.crclbar. is a halogen anion; X, Y and Z are each independently hydrogen, a halogen atom or haloalkyl group of from 1 to 4 carbon...
45	4216212	Pyrazolidine anti-inflammatory composition and methods of use The anti-inflammatory activity of phenylbutazone, oxyphenbutazone, and other pyrazolidine-based anti-inflammatory drugs is enhanced by administration thereof in conjunction with a phosphonate...
46	4190652	Combating pests with O-phenyl-thionothiolalkanephosphonic acid esters O-Phenyl-thionothiolalkanephosphonic acid esters of the formula ##STR1## wherein R is alkyl, halogenoalkyl, alkenyl or alkynyl, R1 is alkyl, and R2, R3 and R4 each independently is hydrogen,...
47	4171357	Cyclopropylmethylphosphoric acid derivatives New phosphoric acid derivatives, a process for their manufacture by reaction of cyclopropylmethyl halides with salts of phosphoric acid derivatives, and pesticides containing these new phosphoric...
48	4148878	Inhibition of platelet aggregation with selected phosphoric acid esters A process for inhibiting platelet aggregation or thrombus formation by the addition of a member selected from the group consisting of a compound of the formula: ##STR1## WHEREIN X is an alkyl or...
49	4148879	Inhibition of platelet aggregation with selected phosphonic and phosphinic acid esters A process for inhibiting platelet aggregation or thrombus formation by the addition of a member selected from the group consisting of a compound of the formula: ##STR1## WHEREIN X is an alkyl or...
50	4139616	Fungicidal compositions based on phosphorous acid esters and salts thereof Compositions for controlling fungus disease are disclosed which contain as active material a fungicidally effective amount of at least one compound of the formula ##STR1## IN WHICH R is an...

Matches 1 - 50 out of 89

1 2 >