Patents in Class 514/13

Matches 1 - 50 out of 894

Match	Document	Document Title
1	7618944	Encapsulated amyloid-beta peptides The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
2	7615534	Antimicrobial peptides and use thereof Artificially synthesized antimicrobial peptide that does not occur naturally is provided by the present invention. The antimicrobial peptide includes one unit, two units or more units of amino acid...
3	7615533	TPO peptide compounds for treatment of anemia Peptide compounds that bind to and activate the thrombopoietin receptor (c-mpl or TPO-R) or otherwise act as a TPO agonist are disclosed.
4	7612171	DB, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof The present invention relates to identification of a receptor for a satiety factor, which is involved in body weight homeostasis. Mutations in this receptor are associated with obese phenotypes. In...
5	7612044	Melanoma antigens and their use in diagnostic and therapeutic methods The present invention provides a nucleic acid sequence encoding a melanoma antigen recognized by T lymphocytes, designated MART-1. This invention further relates to bioassays using the nucleic acid...
6	7608589	Peptidyl diacylglycerides Peptide and peptides that may be covalently linked to a lipid and methods of using such peptides and lipopeptides to prevent or treat disease are disclosed herein.
7	7605120	Antagonists of the brandykinin B1 receptor The present invention relates to certain biologically active peptides and conjugated peptides which can be used as therapeutics or prophylactics against diseases or conditions linked to B1 as the...
8	7601361	Process for providing antimicrobial surfaces Processes for providing durable antimicrobial surfaces are disclosed that comprise treating a polymer substrate surface with formaldehyde followed by treatment with an antimicrobial peptide....
9	7598343	Pharmaceutical formulations of bivalirudin and processes of making the same Pharmaceutical batch(es) or pharmaceutical formulation(s) comprising bivalirudin as the active ingredient, and a method of preparing the pharmaceutical batch(es) or pharmaceutical formulation(s)....
10	7597904	Metalloproteinase inhibitory agent The present invention relates to an active agent, in particular a metalloproteinase inhibitory agent of casein-derived peptides obtained by hydrolysis of casein by a food grade bacteria. The...
11	7595297	Method of reducing injury to mammalian cells A method of inhibiting the binding between N-methyl-D-aspartate receptors and neuronal proteins in a neuron the method comprising administering to the neuron an effective inhibiting amount of a...
12	7592315	Peptide viral entry inhibitors The present invention provides, inter alia, peptide compositions and methods for treating and preventing Flaviviridae virus (e.g., hepatitis C virus) infections.
13	7589171	Polyamides for treating human papilloma virus The present invention relates to polyamide compositions and therapies for treating cells infected with human papilloma virus (HPV).
14	7589062	Two synthetic peptides for treatment and prevention of cancers Two synthetic peptides, Atroporin (AT) and Kaotree (KT), each consisting of ten amino acids and their use for the treatment and/or prevention of various types of cancers is disclosed. The amino...
15	7589058	Ghrelin analogs The invention comprises peptidyl analogs that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.
16	7582727	Pharmaceutical formulations of bivalirudin and processes of making the same Pharmaceutical batch(es) or pharmaceutical formulation(s) comprising bivalirudin as the active ingredient, and a method of preparing the pharmaceutical batch(es) or pharmaceutical formulation(s)....
17	7582438	EphB receptor-binding peptides The application is related to the identification of peptides that selectively bind to Eph receptors of the B class. Also disclosed are uses of such peptides in the treatment of a variety of...
18	7579319	Methods for improving the structure and function of arterioles The present invention relates to the unexpected finding that vessels smaller than even the smallest arteries (i.e. arterioles) thicken, become dysfunctional and cause end organ damage to tissues as...
19	7579318	Cell penetrating peptides for intracellular delivery of molecules The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX 9 WRAX 9 WRX 1 LX 2 RSLX 9 WX 3 X 4 X 5 X 6 X 7 X 8 (SEQ ID No: 1), wherein X 1 is...
20	7579315	Casein peptides for alleviating or preventing aging of skin Provided is use of a peptide, or a derivative of a peptide, in the manufacture of a medicament effective in alleviating or preventing periodontal disease, wherein the peptide comprises an amino...
21	7576175	Alpha-4 beta-1 integrin ligands for imaging and therapy The present invention provides α 4 β 1 integrin ligands that display high binding affinity, specificity, and stability. The ligands comprise a peptide having n independently selected amino...
22	7576058	Method for importing biologically active molecules into cells The present invention relates to the delivery of biologically active molecules, such as peptides, nucleic acids and therapeutic agents, into the interior of cells by administering to the cells a...
23	7576056	Peptides and compounds that bind to a receptor Peptide compounds that bind to and activate the thrombopoietin receptor (c-mpl or TPO-R) or otherwise act as a TPO agonist are disclosed.
24	7572599	Metalloprotease activation of myostatin, and methods of modulating myostatin activity It has been determined that metalloprotease cleavage of a myostatin pro peptide results in activation of a latent inactive myostatin to an active form. Accordingly, methods of identifying agents...
25	7569547	Inhibiting furin with polybasic peptides Small, polybasic peptides are disclosed that are effective as furin inhibitors, e.g. hexa- to nona-peptides having L-Arg or L-Lys in most positions. Removing the peptide terminating groups can...
26	7569546	Apolipoprotein A1 mimetics and uses thereof The present invention provides peptidomimetics derived from Apolipoprotein A-I, which is useful for beneficially influencing lipid parameters and/or plasma cholesterol levels. The invention also...
27	7569542	Anti-microbial targeting chimeric pharmaceutical The present invention is based on the discovery of a composition that provides targeted anti-microbial effect. Specifically the composition contains a targeting moiety which recognizes a target...
28	7569540	Method for enhanced parenteral nutrition A method for improved administration of nutrient is provide. The method includes co- or separate administration of a source of nutrients, especially carbohydrates, and insulinotropic peptides and...
29	7566695	Multimeric apoprotein agonists The present invention provides multimeric apoprotein agonists. Pharmaceutical compositions which include a multimeric apoprotein agonist and a pharmaceutically acceptable carrier, excipient or...
30	7563766	Methods and compositions for the promotion of a hair growth utilizing actin binding peptides Disclosed herein are methods and compositions suitable for the promotion of hair growth on humans and other animals. Disclosed embodiments include compositions comprising actin-binding peptides. In...
31	7563761	PNA conjugate for the treatment of diseases associated with HIV The invention relates to peptide nucleic acid (PNA) conjugates which can be used for treating diseases correlated with HIV, wherein the peptide nucleic acid (PNA) inhibits the gene expression of...
32	7557087	Compositions and methods for treating diseases This invention relates to compositions and methods for treatment of vascular conditions. The invention provides arginine polymers and arginine homopolymers for the treatment and/or prevention of...
33	7557083	Gastrokines and derived peptides including inhibitors A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for...
34	7550438	Methods for production of growth-promoting proteins and peptides for kidney epithelial cells Novel growth peptides derived from protein factors having molecular weights of about 22 and 45 kDa stimulate mitogenic activity of epithelial, but not fibroblastic cells, in particular, kidney...
35	7547676	Antagonist peptides to the C5A chemotactic function of vitamin D binding protein It has been demonstrated that one of Vitamin D Binding Protein (DBP) biological functions is to enhance the chemotactic activity of C5 a and C5 a des Arg. The present invention has found that...
36	7544665	Synthesis using peptide intermediate fragments Methods for the solid phase synthesis of T-1249 peptides and peptide intermediates, in particular methods involving synthesizing T-1249 peptide intermediates at low loading factors to produce...
37	7544664	Sequences facilitating penetration of a substance of interest The present invention relates to an amino acid sequence being able to facilitate penetration of a substance of interest inside cells and/or cell nuclei and having the following formula (I) [(X 1 )...
38	7544655	Haptotactic peptides Novel cell attachment peptides having sequences homologous to specific portions of the carboxy terminal sequence of fibrinogen chains are disclosed. The novel peptides, derived from proteins...
39	7541334	Hybrid peptides modulate the immune response The present invention provides an MHC class II antigen presentation enhancing hybrid polypeptide. The hybrid has an N-terminus comprising the mammalian Ii key peptide LRMKLPKPPKPVSKMR (SEQ ID NO:...
40	7541331	Surfactant treatment regimen Regimens for the therapeutic or prophylactic administration of pulmonary surfactant to infants exhibiting or at risk of developing bronchopulmonary dysplasia are disclosed.
41	7531516	Peptidic compounds selectively binding to P-selectin The present invention relates to compounds which bind selectively to the adhesion molecule human P-selectin, and particularly to such compounds comprising a peptide with an amino acid sequence XA x...
42	7531512	Method of use of peptide antagonists of zonulin to prevent or delay the onset of diabetes A method for preventing or delaying the onset of autoimmune diseases is disclosed.
43	7528250	Chroman derivatives and uses thereof Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, p, q, Ar, R 1 , R 2 , R 3 and R 4 are as defined herein. Also provided are methods for preparing,...
44	7528227	Histone H2A peptide derivatives and uses thereof Peptides derived from a segment of human histone H2A, the segment corresponding to amino acid residues 36-44 of human histone H2A, are capable of reducing or ameliorating the extent of injury...
45	7528107	Methods of treating inflammation in mammalian tissues comprising administering human alpha-defensins Human α-defensins are inhibitors of interleukin-1β post transitional processing and release. Interleukin-1β is a key cytokine involved in the initiation and amplification of the inflammatory...
46	7528104	Peptides that bind to the erythropoietin receptor The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat...
47	7527795	Peptide epitopes of apolipoprotein B The present invention relates to antibodies raised against fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including...
48	7524926	Mucin hypersecretion inhibitors and methods of use Peptides are provided that comprise less than 24 amino acids. The peptides have an amino acid sequence selected from the group consisting of: (a) an amino acid sequence having from 4 to 23...
49	7524818	Prosaposin as a neurotrophic factor Prosaposin, saposin C and various peptide fragments of saposin C stimulate neurite outgrowth in vitro. In addition, prosaposin and saposin C promote increased myelination ex vivo. Prosaposin is...
50	7521415	Methods of intracellular peptide delivery Methods and kits for transporting heterologous compounds into cells, particularly mammalian cells, are disclosed. The method involves the pretreatment of the cell with a polycation, cationic...

Matches 1 - 50 out of 894

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