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8920752 Systems and methods for high speed array printing and hybridization  
Novel and improved systems and methods for high speed arraying, hybridization, quantitative development and/or assaying are provided. Some embodiments provide a web based arraying format. Some...
8906831 Single molecule loading methods and compositions  
Methods for non-random loading of single analyte molecules into array structures are provided. The methods allow for distribution of a population of target molecules into a plurality of size...
8815536 Methods and systems for sampling, screening, and diagnosis  
Apparatus, systems, and methods for detecting, screening and sampling of cells are disclosed.
8580344 Stamp usage to enhance surface layer functionalization and selectivity  
This disclosure provides methods, devices and systems for using a stamp to enhance selectivity between surface layers of a substrate, and to facilitate functionalizing selected layers. An array of...
8546598 Silane compounds having a cyclic carbon chain including an alkyne function for functionalizing solid substrates and immobilizing biological molecules on said substrates  
The invention relates to a silane compound including a cycloalkyne functionality, to a method for functionalising a solid substrate, and to the solid substrate thus produced. The silane compound...
8420017 Microfluidic reaction apparatus for high throughput screening  
A microfluidic device is described that has a slug mixing arrangement. A reaction well has an input flow channel with a first valve near the reaction well, and a second valve further from the...
8389273 Polymerase chain reaction method, polymerase chain reaction droplet device, and polymerase chain reaction droplet device array  
The present invention discloses a polymerase chain reaction (PCR) method, a PCR droplet device and a PCR droplet device array. The steps of the method comprise that a liquid comprising an analyzer...
8357490 Integrated instrument performing synthesis and amplification, and a system and method thereof  
An integrated instrument for oligonucleotide synthesis and PCR, and a system and method thereof are disclosed. The integrated instrument is basically composed of two independent modules. The first...
8282896 Devices and methods for holding microfluidic devices  
Carriers or holders for holding microfluidic devices are provided. Some of the carriers that are provided include a hydration control device and/or a source of controlled fluid pressure to...
8242058 Reagents and methods for appending functional groups to proteins  
Methods and reagents for site-selective functionalization of peptides and proteins. The methods most generally involve the reaction of a thioester with hydrazine. Reagents include bifunctional...
7645721 End group activated polymers with oligonucleotide ligands  
A method for coimmobilizing two or more biomolecules on a substrate in a defined ratio is disclosed. The method uses a copolymer conjugated to a number, N, of different types of oligonucleotides....
7595279 Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules  
A polyelectrolyte having multiple exposed functional groups, each such group being capable of covalently bonding to a molecule, is immobilized on a surface for the purpose of bonding to a...
7576037 Process and apparatus for combinatorial synthesis  
Apparatus and methods are described for split synthesis combinatorial chemistry that provides candidate libraries where an even distribution of theoretical products is obtainable through even...
7468280 High throughput preparation of lubricating oil compositions for combinatorial libraries  
A high throughput preparation of a plurality of different lubricating oil compositions for combinatorial libraries and subsequent high throughput screening for lubricant performance is provided....
7442502 Biochip  
When the genetic analysis is performed by using a DNA microarray, the inspection accuracy is improved. A sample solution is supplied onto a base plate to prepare the DNA microarray comprising a...
7354389 Microarray detector and methods  
A detector for optical analysis of a biochip determines the focal position of a plurality of analytes on the biochip using one or more registration markers on the biochip, wherein the analytes and...
7332274 Process of quality examining for microarray of biological material  
The present invention relates a process of quality examining for microarray of biological material. More particularly, the present invention is directed to a process of quality examining for...
7282330 Methods and apparati using single polymer analysis  
The invention relates to methods for analyzing and characterizing single polymers such as nucleic acid molecules. In preferred embodiments, the single molecules are analyzed using single molecule...
7226733 Microcavity biosensor and uses thereof  
A biological sensor which includes: a porous semiconductor structure comprising a central layer interposed between upper and lower layers, each of the upper and lower layers including strata of...
7217512 Reagent and method for attaching target molecules to a surface  
The present invention provides a method and reagent composition for attachment of target molecules onto the surface of a substrate, such as microwell plates, tubes, beads, microscope slides,...
7217520 Microwell biochip  
Microwell biochips (11) are formed from a thin flat plate (13) of polymeric material having a plurality of regularly spaced holes (15) that extend completely therethrough and create microwells....
7163794 Nucleic acid based nano-robotic system  
A multiped, capable of traveling in more than one direction along a molecular path in a nano-robotic system where the steps taken by the feet of the multiped are controlled in a sequence specific...
7122323 Apparatus and method for synthesizing combinatorial libraries  
An apparatus and method for synthesizing a combinatorial library comprising a plurality of chemical compounds such that the chemical composition of each compound is easily tracked. The library...
7105292 Screening methods used to identify compounds that modulate a response of a cell to ultraviolet radiation exposure  
The cellular response to ultraviolet radiation exposure has been characterized on the molecular level through the use of high density gene array technology. Nucleic acid molecules and protein...
6881363 High throughput preparation and analysis of materials  
A rapid throughput method for the preparation, analysis or both of libraries of material samples is provided. According to the method, a plurality of samples is provided. Providing the plurality...
6794137 Gene markers useful for detecting skin damage in response to ultraviolet radiation  
The cellular response to ultraviolet radiation exposure has been characterized on the molecular level through the use of high density gene array technology. Nucleic acid molecules and protein...
6783938 Devices for optical detection of nucleic acid hybridization  
An optical device for determining the presence of a first nucleic acid in a sample comprising a second nucleic acid complementary to the first nucleic acid and able to hybridize with the first...
6737238 Substrate measuring method and device  
To provide a method of making measurements for a sample on the measuring surfaces of a substrate which makes it possible to simplify the control and construction of a measuring device, shorten the...
6733975 DNA chip and its preparation  
An analytical element (typically DNA chip) composed of a solid carrier and a group of nucleotide derivatives or their analogues fixed to the solid carrier can be produced by bringing nucleotide...
6630358 Arrays of proteins and methods of use thereof  
Protein arrays for the parallel, in vitro screening of biomolecular activity are provided. Methods of using the protein arrays are also disclosed. On the arrays, a plurality of different proteins,...
6623968 Parallel flow reactor and apparatus for testing catalysts  
Apparatus for evaluating catalysts, including a multicell holder, e.g., a honeycomb or plate, or a collection of individual support particles, is treated with solutions/suspensions of catalyst...
6602714 Viscosity and mass sensor for the high-throughput synthesis, screening and characterization of combinatorial libraries  
Workstation, apparatuses and methods for the high-throughput synthesis, screening and/or characterization of combinatorial libraries. The invention relates to an array, which permits various...
6567751 Methods and computer system for combinatorial analysis of lighting phosphors  
There is disclosed a method and a computer system enabling high-throughput combinatorial synthesis and screening of lighting phosphors. The system links hardware instrumentation for synthesis and...
6508984 System for creating and testing novel catalysts, reactions and polymers  
A method and system for researching and developing and/or optimizing new catalysts and products in a combinatorial manner is disclosed. The method begins with starting components or a ligand...
6468806 Potential masking systems and methods for combinatorial library synthesis  
Methods and apparatus are provided for the preparation of a substrate having an array of diverse materials, the materials being deposited at spatially addressable, predefined regions. In...
6319668 Method for tagging and screening molecules  
Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid...
6056926 Apparatus and method for parallel coupling reactions  
A device and method for efficiently synthesizing diverse molecular products on substrates. A parent vessel 200 contains a suspension of substrates. The suspension is pressurized with argon and...
6025129 Remotely programmable matrices with memories and uses thereof  
Combinations, called matrices with memories, of matrix materials with remotely addressable or remotely programmable recording devices that contain at least one data storage unit are provided. The...
5753187 Combinatorial chemistry cassette  
A cassette is provided which includes a combinatorial chemistry dish as used in chemical and biological laboratory work. The cassette includes a metal housing which is adjustable in that it can...
5639603 Synthesizing and screening molecular diversity  
A general stochastic method for synthesizing compounds can be used to generate large collections of tagged compounds that can be screened to identify and isolate compounds with useful properties.

Matches 1 - 40 out of 40