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8980638 Use of IMP3 as a prognostic marker for cancer  
Provided herein are methods and compositions for the prognostic evaluation of a patient suspected of having, or having, cancer by assessing the expression of IMP3 in a biological sample of a...
8975030 Method for cancer detection  
The present invention relates to the diagnosis and treatment of cancer, and specifically to a method of diagnosing the presence, status or metastasis of cancer by detecting plasma Hsp90α having ...
8969252 Peptide mediated synthesis of metallic and magnetic materials  
The present invention includes methods for producing magnetic nanocrystals by using a biological molecule that has been modified to possess an amino acid oligomer that is capable of specific...
8969026 Polymeric reverse micelles as selective extraction agents and related methods of MALDI-MS analysis  
Methods for liquid-liquid extraction, as can be effected using polymeric reverse micelles, such methods as can be used in conjunction with various mass spectrometric techniques.
8969287 Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometry  
Disclosed here is a method for measuring the kinetics (i.e., the molecular flux rates-synthesis and breakdown or removal rates) of a plurality of proteins or organic metabolites in living systems....
8961937 Method for detecting amyloid aggregates using styrylpyridazine-one derivatives  
The present invention relates to a composition for detecting beta amyloid aggregates and a composition for diagnosing beta amyloid aggregation disease, comprising a 2-styrilpyridizine-3(2H)-one...
8962340 Real-time assay for the detection of botulinum toxin  
A real-time portable and rapid detection assay to identify the presence of biologically active toxins such as botulinum toxins. The proteolytic activity of BoNT/A is measured using a peptide...
8962705 Material for removing cauxin in cat urine  
A method for removing cauxin in cat urine and a material for removing cauxin are provided. The material for removing cauxin in cat urine comprises a polymer substrate on which surface a...
8951804 Isolation of RNA-protein complexes using cross-linking reagents and oligonucleotides  
Provided herein is a method of sample analysis. In certain embodiments, the method comprises: a) cross-linking protein of a cell using a first compound to produce a first cross-linked product...
8945933 Liquid chromatography-mass spectrometry methods for multiplexed detection and quantitation of free amino acids  
The present invention provides liquid chromatography-mass spectrometry methods and kits for the specific, sensitive and rapid detection as well as quantitation of free amino acids in samples...
8946327 Method for producing synthetic amylospheroid  
Provided is a method for producing synthetic amylospheroids efficiently, the method including agitating a liquid containing amyloid β-peptides in the presence of a plasticizer. Amylospheroid ...
8945932 Methods and compositions for detecting and isolating phosphorylated molecules using hydrated metal oxides  
The invention provides methods for detecting and isolating phosphomolecules using phosphoaffinity materials that comprise a hydrated metal oxide. In an embodiment, a method for detecting a...
8940482 N-end rule protease activity indication methods and uses thereof  
A cell based assay for detection for protease activity is disclosed. In the assay a cell is engineered to express a protease substrate with at least one label, preferably on its C-terminus....
8940545 Mass spectrometry quantitation of P450 isoforms in hepatocytes  
A method for screening a drug for cytochrome P450 (CYP) induction is provided and can include incubating the drug with a microsome-containing biological sample and then quantitating at least one...
8940143 Gel-based bio chip for electrochemical synthesis and electrical detection of polymers  
An embodiment of the invention relates to a biochip comprising at least two measurement electrodes, a synthesis electrode, a ground electrode, a gap between the at least two measurement electrodes,...
8940538 Apparatus and method for quantifying binding and dissociation kinetics of molecular interactions  
The present invention relates to an apparatus for quantifying the binding and dissociation kinetics of molecular interactions of small molecular bio materials with high sensitivity almost without...
8932868 Biosensor using impedimetric real-time monitoring  
A method an system is disclosed for the detection and/or allocation of at least one point mutation in target DNA and/or RNA duplexes. The method comprises obtaining a functionalized surface which...
8927292 Methods of evaluating peptide mixtures  
The presently disclosed subject matter provides methods for evaluating and characterizing peptides, peptide mixtures, and polypeptide mixtures. More particularly, the presently disclosed subject...
8927291 Methods for detecting dithio-containing proteins using quenched fluorophores conjugated to peptides via linkers containing dithio groups  
Disclosed are dithio compounds that include a quenched fluorophore and a non-fluorophore peptide linked via a dithio bond to the fluorophore. The dithio compounds may be used in methods for...
8927220 Method for diagnosing immunoglobulin A nephropathy and TGBM nephropathy  
A protein used as a biomarker for diagnosing IgA nephropathy and TGBM (thin-glomerular-basement-membrane) using urine through a target proteomics method. A diagnosis biomarker protein and a kit for...
8921116 Methods of evaluating diethylamide in peptide mixtures for the preparation of glatiramer acetate  
The presently disclosed subject matter provides methods for evaluating and characterizing peptides, peptide mixtures, and polypeptide mixtures. More particularly, the presently disclosed subject...
8921113 Buffer kit and method of generating a linear pH gradient  
A buffer kit includes a first eluent and second eluent. The first eluent solution includes at least four buffer salts where at least three of the four buffer salts are a monovalent buffer salt,...
8921038 Method for evaluating regenerated cartilage  
A method, according to an embodiment, for evaluating a regenerated cartilage includes allowing a group of cells containing auricular chondrocytes to stand in the presence of a culture medium,...
8921773 Techniques for efficient fragmentation of peptides  
Techniques are described for performing mass spectrometry. A stream of one or more ions is generated. The stream is transmitted into a collision cell over a period of time. In accordance with a set...
8900879 Sensor for detection of a target of interest  
Embodiments of the present disclosure set forth a sensor for detecting a target of interest. One example sensor may comprise an apparatus for binding the target of interest and a draining unit for...
8883966 RAB6KIFL/KIF20A epitope peptide and vaccines containing the same  
The present invention provides oligopeptides comprising the amino acid sequence selected from the group consisting of SEQ ID NOs: 3, 4 and 5. The present invention also provides a pharmaceutical...
8865413 Pancreatic cancer targets and uses thereof  
The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic...
8859290 Inhibitors of influenza endonuclease activity and tools for their discovery  
The invention provides inhibitors of influenza endonuclease activity and tools for their discovery.
8858958 Adjuvant comprising aluminum, oligonucleotide and polycation  
An immunological adjuvant comprises an aluminum salt, an immunostimulatory oligonucleotide and a polycationic polymer, wherein the oligonucleotide and the polymer ideally associate with each other...
8852948 Colorimetric protein analysis method  
A protein analysis instrument and method are disclosed. The method includes mixing a binding dye composition and a protein sample using a homogenizer, measuring a parameter selected from the group...
8841132 Method for detecting compounds containing sulfenic acid using a 1,3-cyclohexanedione-based probe  
The present invention provides compounds of Formula I: wherein: R1 is a label (e.g., a detectable group and an anti-tumor agent); L is present or absent and when present is a linking group; and x...
8834844 Chemical exchange saturation transfer based MRI using reporter genes and MRI methods related thereto  
Featured are a new class of reporter genes including reporter compositions as well as methods, MRI systems and MRI imaging kits related thereto. The genes according to the present invention provide...
8835183 Determination of sFlt-1:angiogenic factor complex  
Methods for determining the presence or amount of a complex comprising a first and second molecular entity are provided, preferably an sFlt-1:PlGF complex. A determination of the presence or amount...
8835179 Real-time monitor solid phase peptide synthesis by mass spectrometry  
Provided are systems, apparatus, materials and methods for directly monitoring products and intermediates of solid phase chemical synthesis such as solid phase peptide synthesis.
8815528 Methods and systems for detecting MHC class I binding peptides  
The present invention is based on the discovery that MHC heavy chain monomers immobilized to a solid surface are still capable of forming detectable conformational epitopes and being detected by...
8809062 Method and apparatus for fractionation-based chemical analyses  
A method (100) for analyzing chemicals includes fractionating a complex sample into at least two sample portions that each includes potions of two polypeptides though in different concentration...
8802631 Peptides and methods for the treatment of gliomas and other cancers  
The invention is based on the discovery that STM/Hop promotes proliferation of human glioblastoma-derived cells but not of normal astrocytes and that the proliferation requires the binding of...
8802443 Method for identifying gambiered guangdong silk  
A method for identifying gambiered Guangdong silk includes the steps of: detecting the surface state of fiber by microscope; detecting the pyrolysis fragments of fabrics by pyrolysis gas...
RE45074 Method of pre-treating sample for measuring saccharified amine and method of measuring saccharified amine  
The present invention provides a method of pretreating a sample containing a glycated amine as an analyte, thereby enabling highly reliable measurement of a glycated amine. A glycated amino acid in...
8796029 System and method for processing target material  
A system for processing a target material includes; a cartridge which stores a material which reacts with the target material, and may include at least one chamber and at least one valve connected...
8785203 Protein detection reagents and methods with dyes and dextrins  
The invention provides reagents, methods and kits for detection of proteins and quantitative determination of protein concentration. The reagents comprise a protein-complexing dye, such as a...
8784929 Bilayers  
A method for producing a bilayer of amphipathic molecules comprising providing a hydrated support and providing a hydrophilic body, and bringing the hydrated support and hydrophilic body into...
8785397 Cosmetic use of apolipoprotein D type proteins  
The subject of the present invention is the use, in particular the cosmetic and/or therapeutic use, of the apolipoprotein D, of polypeptides derived from this protein or of analogues thereof, of a...
8778695 Methods and apparatuses for analyzing biological samples by mass spectrometry  
Methods and apparatuses for analyzing proteins and other biological materials and xenobiotics within a sample. A specimen is generated, which may include an energy absorbent matrix. The specimen is...
8778685 Quantitative fluorescent protein standards  
The present invention provides dual labeled protein standards useful for the simultaneous determination of the molecular weight of a subject protein as well as the relative mass (i.e., amount) of...
8778277 Protein detection reagents and methods with dyes and dextrins  
The invention provides reagents, methods and kits for detection of proteins and quantitative determination of protein concentration. The reagents comprise a protein-complexing dye, such as a...
8778688 High-throughput methods for determining pharmacological levels of plasma D-serine  
Described herein are high-throughput methods of monitoring D-serine levels in plasma. The assay involves the use of strong cation solid phase extraction (SPE) to isolate D-serine from plasma,...
8772038 Detection of saliva proteins modulated secondary to ductal carcinoma in situ of the breast  
A method of differentiating among the presence of ductal carcinoma in situ in the breast, benign fibroadenoma of the breast, and non-cancerous breast tissue in a subject is disclosed. The method...
8772042 Biomarkers for diagnosing alzheimer's disease  
A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies...
8772043 Universal peptide tags for transgene polypeptide analysis by mass spectrometry  
Compositions and methods that allow for the rapid detection and accurate quantification of any polypeptides of interest are provided. Compositions include isolated polypeptides comprising at least...