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8703498 Multi-dimensional chromatographic methods for separating N-glycans  
A multi-dimensional chromatographic method for the separation of N-glycans. The method comprises providing a glycan preparation that includes at least one negatively charged N-glycan. The glycan...
8698031 Separation and manipulation of a chiral object  
Among other things, for use in directional motion of chiral objects in a mixture, a field is applied across the chamber and is rotating relative to the chamber to cause rotation of the chiral...
8691587 Use of SFRP-3 in the assessment of heart failure  
Disclosed is a method for assessing heart failure in vitro including the steps of measuring in a sample the concentration of the marker SFRP-3, of optionally measuring in the sample the...
8685929 Detecting CYP24 expression level as a marker for predisposition to cancer  
This invention pertains to the discovery that an amplification of the CYP24 gene or an increase in CYP24 activity is a marker for the presence of, progression of, or predisposition to, a cancer...
8685739 Urine based detection of a disease state caused by a pneumococcal infection  
There is provided a method of diagnosing a disease state in a subject. The disease state is caused or effected by pneumococcal infection. The method includes obtaining a biological test sample from...
8685741 Methods for diagnosing irritable bowel syndrome  
The present invention provides methods for accurately classifying whether a sample from an individual is associated with an intestinal disorder. In particular, the present invention is useful for...
8685747 Porous materials for biological sample collection  
Methods, apparatuses, and systems for collecting samples using hybrid porous materials that include an organic material and an inorganic material. A method for sample collection includes contacting...
8679769 Detection of endometrial secretion markers for assessment of endometriosis  
The present invention refers to a group of biomarkers and to non-invasive in vitro methods for the diagnosis or prognosis of endometriosis, as well as to a kit to perform said methods.
8673647 Stress evaluating apparatus, method, system and program and recording medium therefor  
According to the method of evaluating stress of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is...
8673644 Serum markers for type II diabetes mellitus  
A method for identifying persons with increased risk of developing type 2 diabetes mellitus utilizing selected biomarkers described hereafter either alone or in combination. The present invention...
8669113 Advanced detection of sepsis  
The present invention relates to methods, monitors and systems measuring lysophosphatidylcholine, its derivatives and/or procalcitonin as well as at least one clinical marker (e.g. temperature or...
8663928 Method for the detection of post-translational modifications  
Method for the detection in homogeneous medium of a post-translational modification of a proteinaceous substrate catalyzed by a cell enzyme, characterized in that the post-translational...
8663993 Automated protein analyzer  
A dye binding method for protein analysis is disclosed. The method includes the steps of preparing an initial reference dye solution of unknown concentration from an initial reference dye...
8666680 Recombinant soluble FC receptors  
Recombinant soluble Fc receptors according to the present invention are characterized by the absence of transmembrane domains, signal peptides and glycoslyation. Such Fc receptors can easily be...
8658427 Means and methods for assessing increased peroxisomal proliferation  
The present invention pertains to the field of toxicological assessments of risk stratification of chemical compounds. Specifically, it relates to a method for diagnosing increased peroxisomal...
8658374 Binding of aggregated forms of proteins  
Aggregating proteins such as IgG, are bound selectively in the presence of the non-aggregated protein using a polyionic binding agent such as dextran sulphate or pentosan (anionic), or polyamine...
8652417 Crystallization media  
A set of crystallization solutions includes a plurality of crystallization solutions of Crystallization Solution Set I, a plurality of crystallization solutions of Crystallization Solution Set II...
8647879 Peptide probe for rapid and specific detection of β-amyloid aggregation  
A peptide probe that generates fluorescence signals rapidly upon recognition of various Aβ aggregates without significant perturbation of samples. The present peptide probes display an increase in ...
8647830 Method for determining amino-terminal proANP in patients having a cardiac disease or being suspected of developing or having a cardiac disease  
The present invention relates to an in vitro method for medical diagnosis, prognosis and therapy follow-up for patients having a cardiac disease or being suspected of developing or having a cardiac...
8647829 Switchable affinity binders  
Methods and kits for binding and releasing biological targets, comprising, a binder comprising an environmentally reactive molecular switch that can switch between a high affinity state, to bind...
8642344 Method for measuring substrate concentration  
The present invention provides a method for measuring a substrate concentration by accumulating an energy resulting from a reaction between a biocatalyst and a substrate recognized by the...
8642349 Artificial neural network proteomic tumor classification  
Here the inventors describe a tumor classifier based on protein expression. Also disclosed is the use of proteomics to construct a highly accurate artificial neural network (ANN)-based classifier...
8637325 Method and apparatus for pyrolysis-induced cleavage in peptides and proteins  
A method and apparatus for conducting the rapid pyrolysis of peptides, proteins, polymers, and biological materials. The method can be carried out at atmospheric pressures and takes only about 5 to...
8633031 Expression quantification using mass spectrometry  
In various aspects, the present teachings provide systems, methods, assays and kits for the absolute quantitation of protein expression. In various aspects, the present teachings provide methods of...
8633034 Methods for evaluating the aggregation of a protein in a suspension including organopolysiloxane and medical articles coated with organopolysiloxane containing a protein solution  
This invention relates to methods for evaluating or inhibiting the aggregation of a protein in an aqueous suspension including organopolysiloxane and medical articles coated with organopolysiloxane...
8628934 System and method for quantifying fragile X mental retardation 1 protein in tissue and blood samples  
A system and method for the detection and quantification of fragile X mental retardation protein (FMRP) in human tissue and blood samples. The system includes several high avidity monoclonal...
8628724 Integrated needle and test strip with aspiration apparatus and method of use  
Methods and systems to collect a sample of bodily fluid from a patient using an integrated needle and test strip assembly are provided. In this novel assembly, the test strip and needle form one...
8628973 Identification of canine proBNP by immunoassay  
The invention relates to a method of determining feline or canine proBNP or fragments thereof, comprising the steps of providing a feline or canine sample,contacting the sample with at least one...
8628727 Compositions, devices and methods for SERS and LSPR  
The present invention relates to compositions, devices and methods for detecting microorganisms (e.g., anthrax). In particular, the present invention provides portable, surface-enhanced Raman...
8623654 Stabilizing agent for control material, control material containing the stabilizing agent, and measurement kit comprising the control material  
An object of the present invention is to provide a control material which can be preferably employed in detection of 1,5-anhydro-D-glucitol and glycoalbumin, which are employed as excellent indices...
8617838 Fluorescent proteins and related methods and compounds  
The invention includes fusion polypeptides including a first fluorescent protein, e.g., a FRET donor protein, a second fluorescent protein, e.g., a FRET acceptor protein, and, linked to at least...
8613907 Compositions that inhibit proliferation of cancer cells  
Disclosed are compositions and methods for reducing the proliferation of cancer cells through targeted interactions with integrins.
8609424 Antibody directed against pro-gastrin releasing peptide, and use thereof  
Disclosed is a novel high-sensitive ProGRP measurement method, which is free from problems such as the fluctuations in measurement values and the operational constraints (e.g., the constraints on...
8609437 Biomarkers for the diagnosis and treatment of pancreatic cancer  
Compositions and methods for use in methods and kits for the detection of an increased risk of pancreatic cancer are provided. Cyst fluid samples isolated from patients that are positive for at...
8609423 Rapid protein labeling and analysis  
The present invention provides methods and compositions for labeling, separating and analyzing proteins, particularly a specific protein of interest within a cell lysate or in a mixture of...
8603758 Prostate carcinogenesis predictor  
A method of detecting prostate tumorigenesis in a subject, the method including the steps of (a) obtaining a sample from the prostate of the human subject, (b) detecting quantitatively or...
8603829 Atherosclerosis marker and use thereof  
A method is provided for diagnosing or predicting atherosclerosis with the use of, as indicators, markers (factors) that allow early detection and progression prediction of the disease and a method...
8603830 Method for the determination of polysorbate 80  
The present invention relates to a method for the determination of polysorbate in a protein-containing sample. The method of the present invention involves the pretreatment of the sample by...
8597958 IL1RL-1 as a cardiovascular disease marker and therapeutic target  
This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to...
8597954 Stool sample processing method and stool sample processing container  
The present invention relates to a stool sample processing method and stool sample processing container the a stool sample processing container provided with a stool collection tool, a suspending...
8597682 Method for manufacturing mesoporous materials, materials so produced and use of mesoporous materials  
The present invention relates to a new synthetise for the preparation of mesoporous structures including mesoporous materials with chiral morphologies and mesoporous materials with local or surface...
8597878 Device and procedure for automated isolation and purification of nucleic acids from complex starting materials of the users choice  
A reaction unit containing a bottom part and a top part for pipetting a liquid, wherein the bottom part contains a reaction cavity with a permeable filter grid insert and the top part contains a...
8597955 HNRNP A3 related peptides and use thereof for diagnosis of rheumatoid arthritis  
The invention relates to a peptide and retro or retro-inverso peptide thereof, with a length of ≦25 amino acid residues, characterized in that the peptide comprises at least one citrulline r...
8592216 Labeling peptides with tertiary amines and other basic functional groups for improved mass spectrometric analysis  
The present invention provides methods for enhancing the fragmentation of peptides for mass spectrometry by modifying the peptides with a tagging reagent containing a functional group, such as a...
8592217 Method of conducting an assay  
The invention is directed to droplet actuator devices and assay methods. The invention includes assay methods of conducting an assay comprising combining a sample with an umbelliferyl derivative,...
8592170 High molecular weight Ngal as a biomarker for chronic kidney disease  
A high molecular weight form of Ngal is provided which can be used to diagnose chronic kidney disease. High molecular weight Ngal is about 75 kDa to about 350 kDa, and comprises non-Ngal proteins,...
8586369 Ion channel-forming peptides  
The invention pertains generally to novel compositions and methods for constructing chemically sensitive ion channels. The compositions and methods include, for example, novel gramicidin A...
8586379 Monitoring treatment of colorectal cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples  
Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a non-small-cell lung cancer patient, head and neck squamous cell carcinoma or...
8586380 Monitoring treatment of head and neck cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples  
Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a non-small-cell lung cancer patient, head and neck squamous cell carcinoma or...
8586370 Chimeric protein, method for manufacturing the same, nano-sensor in which the chimeric protein is fixed, and application thereof  
There is provided a chimeric protein of capsid protein of Hepatitis B virus (HBV) and B domain of Staphylococcal protein A (SPAB); a method for fabricating the same; the substrate and nanosensor...