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8841132 Method for detecting compounds containing sulfenic acid using a 1,3-cyclohexanedione-based probe  
The present invention provides compounds of Formula I: wherein: R1 is a label (e.g., a detectable group and an anti-tumor agent); L is present or absent and when present is a linking group; and x...
8834844 Chemical exchange saturation transfer based MRI using reporter genes and MRI methods related thereto  
Featured are a new class of reporter genes including reporter compositions as well as methods, MRI systems and MRI imaging kits related thereto. The genes according to the present invention provide...
8835183 Determination of sFlt-1:angiogenic factor complex  
Methods for determining the presence or amount of a complex comprising a first and second molecular entity are provided, preferably an sFlt-1:PlGF complex. A determination of the presence or amount...
8835179 Real-time monitor solid phase peptide synthesis by mass spectrometry  
Provided are systems, apparatus, materials and methods for directly monitoring products and intermediates of solid phase chemical synthesis such as solid phase peptide synthesis.
8815528 Methods and systems for detecting MHC class I binding peptides  
The present invention is based on the discovery that MHC heavy chain monomers immobilized to a solid surface are still capable of forming detectable conformational epitopes and being detected by...
8809062 Method and apparatus for fractionation-based chemical analyses  
A method (100) for analyzing chemicals includes fractionating a complex sample into at least two sample portions that each includes potions of two polypeptides though in different concentration...
8802631 Peptides and methods for the treatment of gliomas and other cancers  
The invention is based on the discovery that STM/Hop promotes proliferation of human glioblastoma-derived cells but not of normal astrocytes and that the proliferation requires the binding of...
8802443 Method for identifying gambiered guangdong silk  
A method for identifying gambiered Guangdong silk includes the steps of: detecting the surface state of fiber by microscope; detecting the pyrolysis fragments of fabrics by pyrolysis gas...
RE45074 Method of pre-treating sample for measuring saccharified amine and method of measuring saccharified amine  
The present invention provides a method of pretreating a sample containing a glycated amine as an analyte, thereby enabling highly reliable measurement of a glycated amine. A glycated amino acid in...
8796029 System and method for processing target material  
A system for processing a target material includes; a cartridge which stores a material which reacts with the target material, and may include at least one chamber and at least one valve connected...
8785203 Protein detection reagents and methods with dyes and dextrins  
The invention provides reagents, methods and kits for detection of proteins and quantitative determination of protein concentration. The reagents comprise a protein-complexing dye, such as a...
8784929 Bilayers  
A method for producing a bilayer of amphipathic molecules comprising providing a hydrated support and providing a hydrophilic body, and bringing the hydrated support and hydrophilic body into...
8785397 Cosmetic use of apolipoprotein D type proteins  
The subject of the present invention is the use, in particular the cosmetic and/or therapeutic use, of the apolipoprotein D, of polypeptides derived from this protein or of analogues thereof, of a...
8778695 Methods and apparatuses for analyzing biological samples by mass spectrometry  
Methods and apparatuses for analyzing proteins and other biological materials and xenobiotics within a sample. A specimen is generated, which may include an energy absorbent matrix. The specimen is...
8778685 Quantitative fluorescent protein standards  
The present invention provides dual labeled protein standards useful for the simultaneous determination of the molecular weight of a subject protein as well as the relative mass (i.e., amount) of...
8778277 Protein detection reagents and methods with dyes and dextrins  
The invention provides reagents, methods and kits for detection of proteins and quantitative determination of protein concentration. The reagents comprise a protein-complexing dye, such as a...
8778688 High-throughput methods for determining pharmacological levels of plasma D-serine  
Described herein are high-throughput methods of monitoring D-serine levels in plasma. The assay involves the use of strong cation solid phase extraction (SPE) to isolate D-serine from plasma,...
8772038 Detection of saliva proteins modulated secondary to ductal carcinoma in situ of the breast  
A method of differentiating among the presence of ductal carcinoma in situ in the breast, benign fibroadenoma of the breast, and non-cancerous breast tissue in a subject is disclosed. The method...
8772042 Biomarkers for diagnosing alzheimer's disease  
A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies...
8772043 Universal peptide tags for transgene polypeptide analysis by mass spectrometry  
Compositions and methods that allow for the rapid detection and accurate quantification of any polypeptides of interest are provided. Compositions include isolated polypeptides comprising at least...
8765482 Method and apparatus for lighted test strip  
A test strip with a sample chamber is secured to a meter. The sample chamber in the portion of the test strip that extends out of the meter is illuminated by transmitting light from a light source...
8765950 Reagents for biomolecular labeling, detection and quantification employing raman spectroscopy  
The present disclosure provides isotopically substituted compounds of the formula (II): wherein T, U, V, W, X, Y, Z, R0, R3, R4, R5 and R6 are as defined in the detailed description. The method for...
8765484 Optically encoded particles  
The invention concerns a particle having a code embedded in its physical structure by refractive index changes between different regions of the particle. In preferred embodiments, a thin film...
8759109 Use of female mammal's urine for determination of fetal gender related characteristics  
The present invention provides a method for determining the gender of a fetus by assaying the sex hormones, evaluating the overall reducing/oxidizing (redox) activity, and/or evaluating the radical...
8753892 Phosphodiesterase 4D7 as prostate cancer marker  
The present invention relates to phosphodiesterase 4D7 (PDE4D7) for use as a marker for prostate cancer, and the use of PDE4D7 as a marker for diagnosing, detecting, monitoring or prognosticating...
8748116 1L1RL-1 as a cardiovascular disease marker and therapeutic target  
This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to...
8741556 Method for quantifying biomolecules  
The present invention relates to a method that allows comprehensive quantitation of one or a plurality biomolecules, including the entire complement of biomolecules in a sample by comparing their...
8734769 1L1RL-1 as a cardiovascular disease marker and therapeutic target  
This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to...
8728823 Methods for detecting lung cancer and monitoring treatment response  
A method is described for detecting lung cancer comprising detecting an elevated level of a CTAP III-related biomarker in a biological sample from a subject at risk for developing lung cancer....
8715960 Aberrant mitochondrial DNA, associated fusion transcripts and translation products and hybridization probes therefor  
The present invention provides novel mitochondrial fusion transcripts, the parent mutated mtDNA molecules, and the resulting translation products (proteins) for predicting, diagnosing and/or...
8716440 Method of liberating and recovering peptide  
A novel method capable of liberating a peptide from a complex of peptide and albumin and the associated method of recovering the peptide are provided. When a liquid sample containing a complex of...
8703498 Multi-dimensional chromatographic methods for separating N-glycans  
A multi-dimensional chromatographic method for the separation of N-glycans. The method comprises providing a glycan preparation that includes at least one negatively charged N-glycan. The glycan...
8698031 Separation and manipulation of a chiral object  
Among other things, for use in directional motion of chiral objects in a mixture, a field is applied across the chamber and is rotating relative to the chamber to cause rotation of the chiral...
8691587 Use of SFRP-3 in the assessment of heart failure  
Disclosed is a method for assessing heart failure in vitro including the steps of measuring in a sample the concentration of the marker SFRP-3, of optionally measuring in the sample the...
8685929 Detecting CYP24 expression level as a marker for predisposition to cancer  
This invention pertains to the discovery that an amplification of the CYP24 gene or an increase in CYP24 activity is a marker for the presence of, progression of, or predisposition to, a cancer...
8685739 Urine based detection of a disease state caused by a pneumococcal infection  
There is provided a method of diagnosing a disease state in a subject. The disease state is caused or effected by pneumococcal infection. The method includes obtaining a biological test sample from...
8685741 Methods for diagnosing irritable bowel syndrome  
The present invention provides methods for accurately classifying whether a sample from an individual is associated with an intestinal disorder. In particular, the present invention is useful for...
8685747 Porous materials for biological sample collection  
Methods, apparatuses, and systems for collecting samples using hybrid porous materials that include an organic material and an inorganic material. A method for sample collection includes contacting...
8679769 Detection of endometrial secretion markers for assessment of endometriosis  
The present invention refers to a group of biomarkers and to non-invasive in vitro methods for the diagnosis or prognosis of endometriosis, as well as to a kit to perform said methods.
8673647 Stress evaluating apparatus, method, system and program and recording medium therefor  
According to the method of evaluating stress of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is...
8673644 Serum markers for type II diabetes mellitus  
A method for identifying persons with increased risk of developing type 2 diabetes mellitus utilizing selected biomarkers described hereafter either alone or in combination. The present invention...
8669113 Advanced detection of sepsis  
The present invention relates to methods, monitors and systems measuring lysophosphatidylcholine, its derivatives and/or procalcitonin as well as at least one clinical marker (e.g. temperature or...
8663928 Method for the detection of post-translational modifications  
Method for the detection in homogeneous medium of a post-translational modification of a proteinaceous substrate catalyzed by a cell enzyme, characterized in that the post-translational...
8663993 Automated protein analyzer  
A dye binding method for protein analysis is disclosed. The method includes the steps of preparing an initial reference dye solution of unknown concentration from an initial reference dye...
8666680 Recombinant soluble FC receptors  
Recombinant soluble Fc receptors according to the present invention are characterized by the absence of transmembrane domains, signal peptides and glycoslyation. Such Fc receptors can easily be...
8658427 Means and methods for assessing increased peroxisomal proliferation  
The present invention pertains to the field of toxicological assessments of risk stratification of chemical compounds. Specifically, it relates to a method for diagnosing increased peroxisomal...
8658374 Binding of aggregated forms of proteins  
Aggregating proteins such as IgG, are bound selectively in the presence of the non-aggregated protein using a polyionic binding agent such as dextran sulphate or pentosan (anionic), or polyamine...
8652417 Crystallization media  
A set of crystallization solutions includes a plurality of crystallization solutions of Crystallization Solution Set I, a plurality of crystallization solutions of Crystallization Solution Set II...
8647879 Peptide probe for rapid and specific detection of β-amyloid aggregation  
A peptide probe that generates fluorescence signals rapidly upon recognition of various Aβ aggregates without significant perturbation of samples. The present peptide probes display an increase in ...
8647830 Method for determining amino-terminal proANP in patients having a cardiac disease or being suspected of developing or having a cardiac disease  
The present invention relates to an in vitro method for medical diagnosis, prognosis and therapy follow-up for patients having a cardiac disease or being suspected of developing or having a cardiac...