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5773299 |
Methods for the rapid analysis of the reticulocytes
A method and reagent for the simultaneous or independent enumeration of reticulocytes in a whole blood sample, without the need to separately incubate the sample and reagent. The reagent contains a...
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5770451 |
Liquid lipoprotein control
An accurate, stable, liquid lipoprotein control composition is provided. The control composition of the present invention preferably contains lipoprotein, surfactant and a divalent cation. The...
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5770452 |
Quantitative determination of lipid, and of co-existing two compounds
Lipid is determined quantitatively by treating a sample with a surfactant in an aqueous medium to obtain a liquid sample dispersion, then reacting the dispersion with a reagent containing cupric...
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5763280 |
Cyanide-free lytic reagent composition and method for hemoglobin and cell analysis
A cyanide-free lytic reagent composition and method for measuring the total hemoglobin concentration in a blood sample, for counting the number of leukocytes and for deferential counting of three...
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5753510 |
Calibrator for use in test methods for detecting a defective coagulation factor V
The invention relates to a plasma which can be used as a calibrator in coagulation tests which detect the degradation of factor V by activated protein C, to the preparation of such a plasma and to...
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5747349 |
Fluorescent reporter beads for fluid analysis
The present invention provides a method and apparatus for rapid measurement of a fluid bulk analyte, requiring only microscale volumes. Several fluid bulk analytes can be measured simultaneously...
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5736103 |
Remote-dosing analyte concentration meter
A meter is used in conjunction with a hollow, frustum-shaped disposable device to measure the concentration of an analyte in a sample of a biological fluid. The smaller end of the frustum has a...
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5736401 |
Stabilized standards and calibrators containing rapamycin and tactrolimus bound to FK binding proteins
The present invention is directed to an in vitro aqueous composition comprising a drug, preferably tacrolimus or rapamycin, having enhanced stability. The invention utilizes a binding protein,...
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5733784 |
Reagent system and method for the differentiation and identification of reticulocytes
Whole blood is mixed with a reticulocyte reagent system that has a reticulocyte staining reagent and a diluent reagent, used in combination. This mixture is incubated at room temperature for...
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5728582 |
Monitoring method of stain solution for particle analysis and calibration method of particle analysis
Sample fluids including biological particles are mixed with a stain solution, and stained biological particles are fed into a flow through cell. Still frame images of the particles flowing through...
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5728519 |
Assay for virulent revertants of attenuated live vaccines and kits therefor
The present invention provides a method of classifying an unclassified live poliovirus vaccine as having an acceptable or unacceptable level of neurovirulence, comprising, prior to vaccine...
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5693517 |
Reagents and methods for coupled high temperature reverse transcription and polymerase chain reactions
Methods are provided for the replication and amplification of RNA sequences by thermoactive DNA polymerases. In a preferred embodiment, high temperature reverse transcription is coupled to nucleic...
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5693252 |
Generation of chlorine dioxide in a non-aqueous medium
A method of preparing chlorine dioxide in a non-aqueous liquid is disclosed. An aqueous solution of chlorine dioxide is mixed and agitated with a non-aqueous liquid. The chlorine dioxide is...
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5691204 |
Compositions and methods for the rapid analysis of reticulocytes
A method and reagent for the simultaneous or independent enumeration of reticulocytes in a whole blood sample, without the need to separately incubate the sample and reagent. The reagent contains a...
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5686316 |
Methods and reagents for the rapid determination of glycated hemoglobin
The invention is a rapid, continuous test for glycated hemoglobin using a non-equilibrium affinity binding method. Agarose beads derivatized with 3-aminophenylboronic acid specifically bind...
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5679287 |
Uses of heptafluoropropane
A method for storing atmosphere sensitive product includes providing an atmosphere surrounding the product which contains at least about 5% heptafluoropropane, preferably at least about 20%...
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5660978 |
Stabilization of analytes
A method for stabilizing analytes with antibodies and antibody fragments comprises dissolving the analyte in a liquid to form a solution, adding analyte-specific antibodies, fragments of such...
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5658451 |
Method for calibration of a pH measuring element
In a method for calibration of a pH measuring element whose ion-permeable, hydrophilic polymer layer is brought into contact with an aqueous solution prior to calibration, the aqueous solution is...
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5656498 |
Freeze-dried blood cells, stem cells and platelets, and manufacturing method for the same
The present invention provides a method for manufacturing freeze-dried blood cells, stem cells and platelets comprising the steps of: pre-treating a liquid selected from the group consisting of...
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5651876 |
Interference suppressing buffer
The present invention is a reagent which, when added as a conditioning solution to samples containing calcium and magnesium, selectively converts the calcium into a complex which does not interfere...
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5648220 |
Methods for labeling intracytoplasmic molecules
The invention features a method of labeling a cell containing an intracytoplasmic target molecule involving (1) permeabilizing the plasma membrane of the cell so that (a) a reagent capable of...
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5643800 |
Method of preparing a sample for analysis by laser desorption ionization mass spectrometry
The present invention is a sample preparation system and method that can be used with all types of analyte materials, that produces homogeneously deposited crystals across a sample surface, and...
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5641637 |
Method of preparing lyophilized and frozen cell standards
A method is disclosed for preparing lyophilized and frozen cells as cytometry standards.
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5637505 |
Method to prepare dye-based reference material
Provided is a method of preparing dye-based reference materials useful for calibrating or qualifying instrument systems that are diagnostic spectroscopically for hemoglobin and CO-ox fractions. The...
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5635406 |
Stabilized standards and calibrators containing rapamycin and tacrolimus bound to anti-rapamycin and anti-tacrolimus antibodies
The present invention is directed to an in vitro aqueous composition comprising a drug, preferably tacrolimus or rapamycin, having enhanced stability. The invention utilizes a binding protein,...
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5633166 |
Method of analyzing medical specimens with improved length of analytical run determination
In high volume laboratory analysis of patient medical specimens, control materials are inserted at periodical intervals (e.g. once per eight hours) and analyzed. If the results of the analysis...
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5627076 |
Method for determination of glycols and polyglycols in drilling fluid filtrates
An apparatus and method is presented for the determination of water soluble glycols and polyglycols (polyalkoxylates). The apparatus and method are particularly suited for the on-site quantitation...
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5627075 |
Stable diagnostic reagent
The inclusion of succinic acid or a salt thereof to stabilize compositions that include glucose oxidase and/or ferricyanide. Typically, the succinic acid or succinic acid salt is included in a...
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5618732 |
Method of calibration with photoactivatable chemiluminescent matrices
Methods for labeling a material are disclosed. The methods comprise combining with the material (a) a photosensitizer capable upon irradiation of generating singlet oxygen and (b) a...
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5618734 |
Method for measuring 3-deoxyglucosone derivatives in a sample
For determining 3-deoxyglucosone derivatives which are intermediate metabolites of the Maillard reaction in body fluids such as blood, urine, serum, plasma and the like in gas chromatography/mass...
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5607856 |
Soil treatment for agriculture
This invention provides for compositions and methods for sterilizing soil using oxygen radicals. The soil is treated with an aqueous solution of an activated oxygen species after pretreatment with...
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5605837 |
Control solution for a blood glucose monitor
A control solution for use with a photometric blood glucose strip contains glucose in an aqueous suspension of carbon black. The control solution mimics blood when applied to a whole blood glucose...
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5599660 |
Method and preparation for sequential delivery of wax-embedded, inactivated biological and chemical reagents
A method and preparation for the storage and delivery of purified reagents is disclosed. In one aspect, the preparation comprises an amount of a first wax carrier, the first wax carrier having a...
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5591403 |
Portable prothrombin time test apparatus and associated method of performing a prothrombin time test
A portable device for performing coagulation tests on a patient's blood. Blood is first drawn from a patient using a lancet. The blood is then supplied to a disposable cuvette placed within the...
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5589393 |
Method for preparing a glycated hemoglobin solution
The invention is a rapid, continuous test for glycated hemoglobin using a non-equilibrium affinity binding method. Agarose beads derivatized with 3-aminophenylboronic acid specifically bind...
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5578194 |
Calibration of electrodes
A CO 2 electrode can be calibrated with two PCO 2 calibration standard solutions having known pH values and known bicarbonate ion source concentrations. An O 2 electrode can be calibrated using...
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5576216 |
Universal standard reagents, method of preparing same and use thereof
A universal standard chemical reagent for quantitative visual and spectrometric analysis of compounds having reactive functional groups, including mixtures and homologs of said compounds, said...
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5576212 |
Oxidizing composition in powder form
An oxidizing composition in the form of powder for oxidizing a chemiluminescent substance, including an oxidizing agent and a binder.
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5573952 |
Process for controlling concentration of a solution of a solvent and polymer
A process for measuring and controlling the concentration of a solution at an aim point of an amide solvent and aramid polymers having aromatic and aliphatic carbon-hydrogen bonds that overlap...
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5571643 |
Spectrophotometric quantitation of images in X-ray film and electrophoresis gel bands
Images comprised of silver such as X-rays and electrophoresis gel bands, wherein the size and darkness of the image provides useful information, are quantitated utilizing a spectrophotometer to...
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5559035 |
Solid phase calibration standards
Solid phase ionic calibration standards are disclosed that comprise sparingly and selectively soluble solids. The calibration standards are especially useful in calibration pH electrodes used to...
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5554527 |
Agent for the storage and suspension of cells, especially erythrocytes
The invention relates to an agent for the preservation, storage and suspension of cells, especially erythrocytes, which contains a chelating agent for multiply charged metal ions, in addition to...
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5554539 |
Determination of an analyte
A method and kit are disclosed for recalibrating a factory-prepared relationship between concentration and expected signal R exp produced by an analyzer. The method and kit use two or three...
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5550053 |
Method of calibrating an automatic chemical analyzer
A method for calibrating an automatic chemical analyzer whereby an improved baseline value is calculated. The analyzer uses a photodetector to detect the amount of light passing through a flow cell...
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5547873 |
Compositions for stabilizing proteins for long term dry storage and methods of making and using the compositions
The invention relates to a composition for stabilizing proteins for long term dry storage and superior recovery of their native protein structure for extended reconstituted stability at 2°-8° C....
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5547875 |
Recalibrating apparatus and method
A method and apparatus for recalibrating analytical instruments such as atomic absorption and inductively coupled plasma spectrophotometers comprises the use of coupled piston pumps and valves in a...
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5541116 |
Method for the stabilization of endogenous, physiologically active peptides
Method for the stabilisation of endogenous physiologically active peptides in human whole blood, serum and plasma samples before and/or during the determination of the-concentration of these...
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5538893 |
Reagent for analyzing leukocytes and a method for classifying leukocytes
A reagent for analyzing leukocytes having at least one nonionic surfactant having an addition polymerization molar number of polyoxyethylene of 3 to 9, at least one cationic surfactant, and a...
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5527706 |
Method for mixing two initial solutions
In a process for mixing two initial solutions to produce a working solution with an accurately defined mixing ratio, the two initial solutions are coarsely mixed in a first step, having a mixing...
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5518928 |
Leukocyte differentiation method
A method is disclosed for differentiating white blood cells. The method uses at least one surfactant and at least one dilute acid which together selectively strip the cytoplasm from certain classes...
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