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5288642 |
Shelf-stable milk calibration standards
A calibration standard for calibrating machines which count the somatic cells in a milk sample, comprises an aqueous dispersion of microbeads bearing a fluorescent dye, a suspending agent, and an...
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5284770 |
Meter verification method and apparatus
A method and apparatus for verifying the operating accuracy of an instrument (10) for detecting the concentration of a medically significant component of a body fluid. The instrument (10) operates...
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5281536 |
Stable liquid control serum or calibration system for use in clinical diagnostics
A stable liquid control and/or calibration serum for use in clinical diagnostics containing a liquid-stable bilirubin derivative and a known concentration of at least one analyte. The invention...
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5273888 |
Chemical test kit and method for determining the presence of blood in a specimen and for verifying the effectiveness of the chemicals
A chemical test kit for determining the presence of occult blood in a stool specimen is disclosed which includes an improved monitor system for verifying the effectiveness of the chemicals used in...
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5262327 |
White blood cell hematology control
Reference controls comprised of aldehyde-fixed white blood cells exhibiting a white blood cell histogram profile that is substantially that of whole blood are obtained by the additions of a...
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5258308 |
Method, kit and apparatus for verifying calibration and linearity of vertical photometers
A method and apparatus for calibrating or checking the calibration of vertical photometers. The invention may also provide easy and convenient assay results for diagnostic profiles. The invention...
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5256571 |
Cell preservative solution
An aqueous alcohol buffer solution for substantially ambient, in vitro preservation of mammalian cells for a selected duration. The solution generally contains a water-miscible alcohol in an amount...
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5250437 |
Reagent for simultaneous determination of hemoglobin and leukocytes in blood
A reagent for measuring the hemoglobin concentration and counting the number of leukocytes in a blood sample, which contains at least one of a quaternary ammonium salt or a pyridinium salt, having...
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5248615 |
Calibrator composition for prolactin assay
A stabilized prolactin calibrator is disclosed. The calibrator has a pH from about 5.5 to about 9.0, and contains prolactin in a 0.01 M to 0.2 M matrix of tris-(hydroxymethyl)aminomethane which...
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5246858 |
Apparatus and method for analyzing a body fluid
A method and apparatus (10) for determining the remission of a chemistry (106) which reacts with a medically significant component of a body fluid. The remission of the chemistry (106) changes as...
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5242832 |
Reagent for measurement of leukocytes and hemoglobin in blood
A reagent, satisfying the undermentioned conditions, is useful for counting the number of leukocytes and measuring the hemoglobin concentration in blood samples. The reagent is free of cyanides and...
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5238845 |
Method for producing a CO.sub.2 calibration liquid
A method for producing a liquid phase substance having a pre-established concentration of CO 2 suitable for calibrating analytical instruments such as hemogasanalyzers consists in: preparing an...
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5233860 |
Water measuring system with improved calibration
A water measuring system for measuring different parameters of water having a compact configuration that can be easily calibrated is provided. A plurality of individual sensors, are mounted on the...
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5234835 |
Precalibrated fiber optic sensing method
A precalibrated sensing system for determining a blood parameter such as the partial pressures of oxygen (pO 2 ) and carbon dioxide (pCO 2 ), and the negative logarithm of hydrogen ion activity...
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5231030 |
Temperature insensitive calibration system
A multi-phase control and/or calibration system consists of a liquid phase containing an amount of dissolved oxygen (O 2 ) in which the O 2 partial pressure is made relatively temperature...
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5229294 |
"Kappa" number calibration standard
Instruments for determining the degree of delignification corresponding to a sample of kraft or soda process digested wood pulp are calibrated with a predetermined quantity of refined lignin. For...
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5227305 |
Buffer solution systems for standardizing pH analyzers and electrolytes
A formulation of combined-composition electrolyte and pH buffers for use as standardization solutions in analyzers for clinical chemistry which simultaneously use more than one ion-selective...
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5223433 |
Temperature stabilized fluid calibration system
A method and system for controlling the concentration of one or more gaseous species of interest in a sample medium throughout a range of temperatures in which a temperature related, time variable...
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5213769 |
Mixture forming method and apparatus
The present invention provides an apparatus for forming a mixture containing a regulated, low concentration of a target component within a carrier fluid. In accordance with the present invention,...
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5206141 |
Okadaic acid testing for ciguatoxin
A composition comprising okadaic acid for use as a positive control in assays for the detection of ciguatoxins and methods for making such compositions. In a preferred embodiment, the okadaic acid...
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5204264 |
Method for validation of calibration standards in an automatic chemical analyzer
In an automated analyzer that measures concentration of samples by comparing changes in a detector response caused by said samples to a calibration curve or factor based on one or more different...
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5198365 |
Fecal sample immunoassay method testing for hemoglobin
A method for preparing a fecal sample for immunoassay testing comprising the steps of dispersing a sample of from 1 to less than 10 wt. % of a stool sample in an aqueous fecal test solution...
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5196343 |
Ultrasonic calibration material and method
Ultrasonic calibration material produced by polymerization of acrylamide with N,N'-methylene-bis-acrylamide in vacuum-degassed liquid solutions such as water, ethylene glycol, emulsions of...
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5187099 |
Control slide for immunoassay kit using a low-temperature melting paraffin
A control slide for use in an immunoassay having a section of a cell pellet retained on the slide in a stable and substantially permanent formation which can be stored at room temperature. Further,...
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5185263 |
Method for calibration of a measurement apparatus
In order to calibrate a measurement apparatus used for determining at least the pH and pCO 2 values in aqueous media, two aqueous base solutions A and B with good storage stability are mixed at a...
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5183761 |
Method of making calibration solution for verifying calibration and linearity of vertical photometers
A method and device for calibrating or checking the calibration of vertical photometers. The invention may also provide easy and convenient assay results for diagnostic profiles. The invention...
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5180677 |
Lysing reagent for leukocyte differentiation method
A lysing reagent is employed for stromatolysing the red cells in a blood sample and differentiating the leukocytes into subpopulations. The lysing reagent contains a dodecyltrimethylammonium halide...
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5171029 |
Seal construction for pump apparatus
An endless path calibration system comprising a sensor cassette having a flow-through passage and at least one sensor to be calibrated, a chamber coupled to the sensor cassette to define an endless...
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5166078 |
Hapten-macromolecule conjugates useful in hapten assays
The invention is a method for measuring a hapten poorly soluble in aqueous solution in a sample which includes the steps of reacting the hapten with an antibody specific for the hapten; and...
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5166079 |
Analytical assay method
A method for determining the amount of an analyte in a sample fluid utilizes a multilayer assay element which comprises at least one reagent layer and a light-blocking layer. The assay method...
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5151372 |
Method for determination of hydroxyacetophenone derivatives
There is provided a method for determination of hydroxyacetophenone derivatives such as 3,5-dichloro-4-hydroxyacetophenone in the presence of protein such as albumins or globulins with high...
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5145565 |
Contamination-free method and apparatus for measuring body fluid chemical parameters
A sample of a body fluid, such as blood, is collected in a cartridge having a sample chamber for storing the sample and one or more calibration chambers, each for storing a respective calibration...
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5143848 |
Method of stabilizing colostrum for immunochemical examination
A method of stabilizing a sample of colostrum or milk which is intended for immunochemical examination, by adding a stabilizing system which comprises the following components: (a) a...
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5142031 |
Method for labelling sugars
Disclosed herein is a method of labelling a sugar at its reducing end by using 1-(p-methoxyphenyl)-3-methyl-5-pyrazolone, thereby analyzing said sugar with high sensitivity, and to a kit to be used...
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5132230 |
Primary standard and method of making secondary standards for calibration of glycated protein assays
This invention provides a primary standard and/or secondary standards for assay for glycated proteins in samples such as blood. The primary standard is composed of a polymer or copolymer of an...
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5116728 |
Reagents for CO.sub.2 detection
A stabilizer for maintaining a constant level of CO 2 in coenzyme containing enzymatic CO 2 diagnostic reagents is disclosed, comprising rate-limiting amounts of (a) the diagnostic reagents and...
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5116726 |
Methods for removal of detergents from analytes
Compounds having detergent properties are disclosed. When a modifying reagent is brought into contact with these compounds, the detergent properties are decreased. These compounds are useful, for...
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5116762 |
Method for determining the concentration of fructosamine using a standard solution and method of calibrating the standard solution
The present invention provides a process for the determination of fructosamine in body fluids using as a standard, a solution which contains a peptide or protein, the amino acid units of which...
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5114672 |
Method for preserving blood fluid
In a method for preserving umbilical cord blood, a severed umbilical cord is provided which has at least one tubular blood vessel closed at opposite ends to maintain fluid in the vessel. An...
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5112758 |
Treating body fluids for diagnostic testing
A method of reducing the viscosity of a body fluid comprises mixing a body fluid with a cationic quaternary ammonium reagent. The body fluid is a mucopolysaccharide-containing body fluid which will...
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5096827 |
Composition for preventing unwanted oxidation of redox indicators
The present invention is directed to a reliable redox indicator composition for use in chemical assay systems and is particularly well suited for assay systems using a dry phase format. More...
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5094956 |
Fecal sample immunoassay composition and method
A method for preparing a fecal sample of immunoassay testing comprising the steps of dispersing a sample of from 1 to less than 10 wt. % of a stool sample in an aqueous fecal test solution...
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5093234 |
Method of aligning, compensating, and calibrating a flow cytometer for analysis of samples, and microbead standards kit therefor
A kit of highly uniform size microbead standards for flow cytometer alignment, compensation, and/or calibration, comprising a blank microbead population and/or an auto-fluorescent microbead...
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5089416 |
Method of use of non-fluorescent particles to determine fluorescence threshold of a flow cytometer relative to the autofluorescence of samples
A qualitative and quantitative method of determining the fluorescence threshold of an instrument and of determining whether the instrument is sensitive enough to measure the autofluorescence of a...
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5084394 |
Method for corrective calibration of a flow cytometry using a mixture of fluorescent microbeads and cells
The use of a combination of calibrated microbead populations with one or more calibrated biological cell populations to correct calibration of a flow cytometer for size and fluorescence intensity...
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5073497 |
Microbead reference standard and method of adjusting a flow cytometer to obtain reproducible results using the microbeads
A flow cytometer reference standard containing a highly uniform microbead population, wherein each microbead has the same multiple fluorescent labels as the other microbeads and as the samples to...
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5073498 |
Fluorescent alignment microbeads with broad excitation and emission spectra and its use
Highly uniform microbeads containing a single fluorescence dye or a mixture of fluorescence dyes, which can be excited over a wide range of the spectrum extending from the ultraviolet to the...
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5071767 |
Process for the determination of fructosamine in body fluids and calibration solution
For the determination of fructosamine in body fluids a solution containing fructosamine and albumin is used as the standard solution for calibration which standard solution is essentially free of...
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5070023 |
Aqueous ferrioxalate compositions useful as calibrants
Aqueous acidic ferrioxalate compositions are disclosed for use as calibrants of pCO2 and of PO2 after photodecomposition. Compositions with high iron(III) to oxalate molar ratios (e.g., 5:1 to...
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5059518 |
Stabilized lyophilized mammalian cells and method of making same
A method of lyophilizing mammalian cells to produce preserved human cells, hybridoma cell lines, tissue cells, and control cells for immunoassays and other hematological measurements. Prior to...
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