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7629179 |
Surfaces coated with target-induced fluorescent compounds for detection of target elements
Surfaces coated with a target-induced fluorescent compound are used to detect target elements, especially trace elements. The target-induced fluorescent compound does not fluoresce when excited at...
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7572641 |
Pharmaceutical compositions comprising meloxicam and methods of their preparation
The present invention encompasses a method of evaluating pharmaceutical compositions of meloxicam whereby one can correlate in vitro properties to in vivo properties, and pharmaceutical...
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7534560 |
Simple catalytic DNA biosensors for ions based on color changes
Disclosed are compositions and methods for the sensitive and selective detection of ions using nucleic acid enzymes and DNA modified microparticles.
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7507583 |
Analysis of large soil samples for actinides
A method of analyzing relatively large soil samples for actinides by employing a separation process that includes cerium fluoride precipitation for removing the soil matrix and precipitates...
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7494821 |
Fluorescein based sensors for tracking nitric oxide in live cells
The present invention is directed, in part, to coordination complexes for detecting analytes, and methods of making and using the same.
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7491545 |
Excitation ratiometric fluoroscent biosensor for zinc ion at picomolar levels
A highly selective and sensitive of a carbonic anhydrase-based method for measurement of zinc ion by an excitation ratiometric format based on resonance energy transfer: i.e., where the zinc ion...
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7482135 |
Proteolytic enzymes in urine as diagnostic parameters in diseases involving matrix remodelling
A method for determining whether a urine sample has been obtained from a subject suffering from a kidney disorder involving kidney damage. The method is based on determining the level of a...
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7476551 |
Diagnosing atherosclerosis risk by measuring carbamylated low density lipoprotein levels
The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of: measuring the level of carbamylated LDL in a sample obtained...
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7473558 |
Marker useful for detection and measurement of free radical damage and method
The present invention teaches a marker useful for detection and measurement of free radical damage. Specifically, the invention takes advantage of alterations which occur to the N-terminus of the...
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7465585 |
Compositions and methods for inhibiting cell migration
The finding that Dickkopf1 (Dkk1) is a dual function protein demonstrates a mechanism for the coordination of cell migration and antagonism of Wnt/β-catenin signaling during developmental and...
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7452728 |
Metal ion separation from aqueous solutions using photoswitchable ionophores
Methods and systems for the concentration and removal of metal ions from aqueous solutions are described, comprising treating the aqueous solutions with photoswitchable ionophores.
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7445908 |
Detection of oxidizing agents in urine
A method of detecting oxidants in a biological sample comprising: adding a source of ferrous ions to said sample, whereby the presence of oxidants in said sample oxidize at least a portion of said...
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7399639 |
Sensors, and methods of making and using the same
The present invention is directed, in part, to sensors for detecting metal ions, and methods of making and using the same.
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7312083 |
Control value assignment method
A method of assigning expected recovery values to control substances used in analytical testing is disclosed.
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7247489 |
Ion-detecting microspheres and methods of use thereof
This invention provides methods of using ion-detecting microspheres containing an ionphore and a chromoionphore in clinical laboratory instrumentation such as flow cytometry for sample analysis. In...
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7226563 |
Ion-detecting sensors comprising plasticizer-free copolymers
Plasticizer-free ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers...
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7208121 |
Plasticizer-free-ion-detective sensors
A plasticizer-free ion detective sensor for detecting a target ion in a sample is provided. The sensor comprises a copolymer of methacrylate monomers with pendant alkyl groups of different length,...
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7201876 |
Ion-detecting sensors comprising plasticizer-free copolymers
Ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers having pendent...
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7160732 |
Fluorescein-based metal sensors, and methods of making and using the same
The present invention is directed, in part, to fluorescein-based ligands for detection of metal ions, and methods of making and using the same.
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7148068 |
Method of trivalent chromium concentration determination by atomic spectrometry
A method is disclosed for determining the concentration of trivalent chromium Cr(III) in a sample. The addition of perchloric acid has been found to increase the atomic chromium spectrometric...
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7090995 |
Molecules and methods using same for measuring non-transferrin bound iron
A molecule suitable for use as an indicator of free iron levels in a biological sample, the molecule including an iron binding moeity and a signal generating moeity, wherein an intensity of the...
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7067320 |
Sensor for luminescense-optical determination of an analyte
The invention relates to an optochemical sensor functioning in accordance with the FRET-principle and exhibiting an acceptor (chromophore or luminophore) responsive to an analyte contained in a...
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6905655 |
Modification of selectivity for sensing for nanostructure device arrays
An electronic system for selectively detecting and identifying a plurality of chemical species, which comprises an array of nanostructure sensing devices, is disclosed. Within the array, there are...
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6858440 |
Tapered tubular optical waveguide probe for magnetic focusing immunosensors
A waveguide probe for the detection of pathogens in a sample which comprises a laser, a first and a second tubes that converge at a point to form a proximal end. A magnet is positioned in the end...
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6846299 |
Method for continuous recirculating peritoneal dialysis
Method for a continuous recirculating peritoneal dialysis wherein the peritoneal dialysis fluid is infused into a peritoneal cavity of a patient and then, typically on a continuous process basis a...
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6821786 |
Diagnostic test for elemental imbalances
A self-diagnostic test, a self-diagnostic test apparatus, and method of manufacturing a self-diagnostic test for screening for elemental mineral imbalances in a patient utilizing an analysis of the...
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6806089 |
Low frequency modulation sensors using nanosecond fluorophores
Described is a new approach to fluorescence sensing based on a mixture of fluorophores, one of which is sensitive to the desired analyte. If a long lifetime analyte-insensitive fluorophore is mixed...
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6800489 |
Electrospray tandem mass spectrometry of transition metal diimine complexes of amino acids, α-hydroxyketones and hexose phosphates for newborn screening
Tandem mass spectrometry (MS/MS) has been used extensively for solving various biological problems, such as structure identification of oligopeptides, nucleic acids, and nucleotides. One of the...
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6790673 |
Speciated isotope dilution mass spectrometry of reactive species and related methods
A method of speciated isotope dilution mass spectrometry (SIDMS) which will permit determination of concentrations of one or more species from a sample even if the sample has been subjected to...
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6756230 |
Quantitative analysis
Amounts of components in a specimen can be analyzed with excellent quantitativity. The analysis includes: measuring an amount of a component to be analyzed in a specimen; measuring an amount of a...
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6740527 |
Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood
Cyanide-free reagents for the determination of hemoglobin and leukocytes present in a blood sample comprise an aqueous solutions of at least one quaternary ammonium salt, preferably selected from...
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6645768 |
Reagent and kit for determining global coagulability and hemostatic potential
A reagent and kit are disclosed for determining if a patient is hypercoagulable, hypocoagulable or normal. The test involves providing a test sample from the patient and initiating coagulation in...
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6627448 |
Analyte-binding assay
Analyte-binding assays, such as iron binding assays, are disclosed. The assays can provide information relating to the serum iron content and/or total iron binding capacity of a sample.
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6602989 |
Synthesis, characterization, and application of pyridylazo bioconjugates as diagnostic and therapeutic agents
The detection of gallium in biological samples is required due to its role in the diagnosis of tumor and for possible treatment of malignancies. However, the use of purely instrumental techniques...
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6541265 |
Method and system to test a substance for inflammatory or oxidant properties
The subject invention pertains to methods and systems for testing a substance for inflammatory or oxidant properties under acute inflammatory conditions characterized by increased levels of...
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6492179 |
Test for rapid evaluation of ischemic states and kit
The present invention relates to a rapid method for the detection of ischemic states and to a kit for use in such a method. Provided for is a rapid method of testing for the existence of and...
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6455317 |
Method of controlling a chemical process by microwave radiation
A system and method for controlling a microwave heated chemical process is disclosed. Time varying concentrations of some chemical substances within fumes in the microwave oven are monitored to...
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6429017 |
Method for predicting the presence of haemostatic dysfunction in a patient sample
A method which may be used to determine haemostatic dysfunction in a patient is carried out by (a) adding a reagent to a test sample, wherein the test sample includes at least a component of a...
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6429294 |
Peritoneal dialysis fluid and method for a continuous recirculating peritoneal dialysis using the same
A peritoneal dialysis fluid used for a continuous recirculating peritoneal dialysis wherein the peritoneal dialysis fluid is infused into a peritoneal cavity of a patient and then, typically on a...
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6383817 |
Cadmium is a risk factor for human pancreatic cancer
The present invention provides a method of screening for risk of pancreatic cancer in a subject, wherein the presence or absence of increased levels of cadmium in the subject is detected and...
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6379969 |
Optical sensor for sensing multiple analytes
A device for analyzing simultaneously multiple analytes in a fluid of unknown composition. The device includes a plurality of sensors, a light source for providing light to shine on the sensors,...
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6368866 |
Rapid separation assay for total iron binding capacity
Methods, reagents and reaction mixtures for determining total iron binding capability is disclosed.
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6344359 |
Spectrophotometric assay for the determination of total vanadium and the &plus IV and &plus V oxidation states of vanadium
A rapid colorimetric assay is provided for determining the concentration of vanadyl and vanadate ion species, and total vanadium concentration, in a sample. A sample suspected of containing...
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6337944 |
Polymeric optical waveguide doped with a lanthanide-sensitizer complex
The invention relates to a polymeric waveguide comprising a lanthanide ion-sensitizer complex, characterized in that the lanthanide ion is preferably neodymium(III) ion (Nd 3+ ), ytterbium(III) ion...
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6323036 |
Reagents and methods for releasing and measuring lead ions from biological matrices
The present invention provides a reagent for extracting lead ions from a variety of biological matrices such as human whole blood that has been anticoagulated with either heparin or EDTA, and...
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6284544 |
Determination of metal ions in solution by photoluminescence anisotropy
Homogeneous fluorescence polarization (anisotropy) assays for detecting and quantifying metal ions in solution, based the metal-dependent binding of a fluorescent ligand to an unlabeled...
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6274382 |
Method and reagent for the interference-free determination of iron
Method and reagent for the determination of iron in a biological sample in which the bound iron is released, the released iron is reduced to Fe 2 +, a color reagent solution is added and the color...
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6248938 |
Animal feed compositions containing phytase derived from transgenic alfalfa and methods of use thereof
A value-added composition of matter containing plant matter from transgenic alfalfa which expresses exogenous phytase activity is disclosed. The phytase activity is a gene product of an exogenous...
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6248592 |
Method for measuring lead concentrations in blood
Method for measuring lead concentrations in blood. The present invention includes the use of resonant laser ablation to analyze ≤1 μL (or equivalent mass) samples of blood for lead content. A...
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6245574 |
Sensors
Sensors for the qualitative and quantitative determination of K + ions in aqueous systems are described, which consist essentially of a carrier and an active layer applied to this carrier, whereby...
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