|
Match
|
Document |
Document Title |
|
|
7615358 |
Method for determining the concentration of vital epithelial tumor cells in a body fluid
A method for determining the concentration of vital epithelial tumor cells in a body fluid is disclosed. The method comprises obtaining from the body fluid of a test subject a test specimen,...
|
|
|
7608696 |
IBC-1 (invasive breast cancer-1), a putative oncogene amplified in breast cancer
This invention encompasses antibodies specific for IBC-1 (Invasive Breast Cancer-1), methods for diagnosis and prognosis of metastatic breast cancer and degenerative neural conditions, methods of...
|
|
|
7605246 |
Genes differentially expressed in breast cancer
A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of...
|
|
|
7605003 |
Use of biomarkers for detecting ovarian cancer
The present invention relates to a method of qualifying ovarian cancer status in a subject comprising: (a) measuring at least one biomarker in a sample from the subject and (b) correlating the...
|
|
|
7598051 |
Compositions and methods for the therapy and diagnosis of ovarian cancer
Compositions and methods for the therapy and diagnosis of cancer, particularly ovarian cancer, are disclosed. Illustrative compositions comprise one or more ovarian tumor polypeptides, immunogenic...
|
|
|
7598028 |
Compositions and methods for detecting and treating prostate disorders
The present invention relates to compositions and methods for the detecting, treating, and empirically investigating cellular proliferation disorders and cellular motility disorders. In particular,...
|
|
|
7575928 |
Genes for diagnosing colorectal cancer
This invention relates to provide the genes for diagnosing colorectal cancer, the gene sequences searching comprise the steps of: (1) deriving epithelium cells from normal intestines, polypus of...
|
|
|
7569356 |
Diagnosis and therapy of cancer using SGP28-related molecules
The present invention relates to methods and compositions for the diagnosis and therapy of prostate cancer which utilize isolated polynucleotides corresponding to the human SGP28 gene, proteins...
|
|
|
7566542 |
Use of protein ASC as a marker for breast cancer
The present invention relates to the diagnosis of breast cancer. It discloses the use of protein ASC in the diagnosis of breast cancer. It relates to a method for diagnosis of breast cancer from a...
|
|
|
7566531 |
Selective whole cell quartz crystal microbalance biosensors
Selective whole cell QCM biosensors are disclosed. Also disclosed are methods of making and using such whole cell QCM biosensors, e.g., to screen drugs and diagnose diseases.
|
|
|
7563584 |
Methods and compositions for detecting the activation state of multiple proteins in single cells
The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides...
|
|
|
7560242 |
Metadherin polypeptides, encoding nucleic acids and methods of use
Metadherin, a protein that controls metastasis, and variants of metadherin are described. DNA sequences encoding the same and methods of production are described. Therapies involving the...
|
|
|
7560226 |
Assay to detect a binding partner
A method can identify a type of leukemia in a human subject. A biological sample from the human subject that contains CD antigens is obtained. The sample is contacted with an array of...
|
|
|
7550256 |
Vimentin directed diagnostics and therapeutics for multidrug resistant neoplastic disease
Disclosed are methods for detecting multidrug resistance in neoplastic or damaged cells or multidrug resistant (MDR) neoplastic or damaged cells by detecting an increase in the cell surface...
|
|
|
7547441 |
PAI-2 conjugates for the treatment and imaging of cancer
A method is described for detecting, visualizing, or treating cells, particularly cancerous cells, that express a uPA/uPAR complex. The method employs a PAI-2 conjugate molecule that comprises...
|
|
|
7537907 |
Products and methods for single parameter and multiparameter phenotyping of cells
A method of single parameter and multiparameter characterizing of cells, particularly immunophenotyping of cells, is provided. The method preferably uses antibody coated microspheres which are...
|
|
|
7534565 |
DLC-1 gene deleted in cancers
A cDNA molecule corresponding to a newly discovered human gene is disclosed. The new gene, which is frequently deleted in liver cancer cells and cell lines, is called the DLC-1 gene. Because the...
|
|
|
7524681 |
Rapid assay for biological substances using FTIR
The present invention relates to a method for determining the condition of a biological fluid by recording the IR spectrum of a sample of the biological fluid. To this end, the biological fluid can...
|
|
|
7517663 |
Rabbit monoclonal antibody against Id1 protein
The present invention relates to a rabbit monoclonal antibody that binds to human Id1 protein and/or mouse Id1 protein with high specificity and high affinity. The antibody has a binding constant,...
|
|
|
7517662 |
Method for solution based diagnosis
This invention provides methods for improved diagnosis of medically relevant conditions by solution based biochemical testing procedures performed in solutions of test samples. The invention...
|
|
|
7511123 |
Immuno-interactive fragments of the alpha-C subunit of inhibin
Novels immuno-interactive fragments of the (alpha)C portion of a mammalian inhibin alpha subunit are disclosed, together with their variants and derivatives for producing antigen-binding molecules...
|
|
|
7507548 |
Multidimensional detection of aberrant phenotypes in neoplastic cells to be used to monitor minimal disease levels using flow cytometry measurements
A method for detecting aberrant phenotypes expressed by neoplastic cells includes the steps of: 1) staining one or more normal/reactive samples and one neoplastic sample with multiple combinations...
|
|
|
7491502 |
In vivo flow cytometry system and method
The present invention provides methods and systems for performing in vivo flow cytometry. In one embodiments, selected circulating cells of interest of a subject are labeled with fluorescent probe...
|
|
|
7485422 |
Detection of CDX2 expression
Screening and diagnostic reagents, kits and methods for metastatic colorectal cancer or primary and/or metastatic stomach or esophageal cancer are disclosed. Vaccines compositions and methods of...
|
|
|
7462491 |
Methods and compositions for diagnosis and monitoring of prostate cancer progression by detection of serum caveolin
Serum cav-1 is disclosed as a biomarker for prostate cancer that has the power to differentiate between prostate cancer and BPH patients.
|
|
|
7452727 |
Method for increasing clinical specificity when detecting tumors and their precursor stages by simultaneously measuring at least two different molecular markers
The present invention relates to an automatable method for the improved diagnosis of pathologically altered cells by simultaneously staining at least two different molecular markers, which exhibit...
|
|
|
7449340 |
Method for the early diagnosis of cancer
The present invention relates to a method for the early diagnosis of cancer in a subject, which is based on determination of the relative fraction of microorganisms derived from the feces of the...
|
|
|
7439234 |
Method for treating cancer patients undergoing chemotherapy
A method for treating cancer patients undergoing chemotherapeutic treatments by administering Product R, a peptide-nucleic acid preparation, is disclosed.
|
|
|
7438890 |
Binding peptides for carcinoembryonic antigen (CEA)
The present invention provides binding moieties for CEA, which have a variety of uses wherever detecting, isolating or localizing CEA, and particularly CEA as opposed to cross-reactive antigens...
|
|
|
7432345 |
PRO1475 polypeptide
The present invention is directed to novel PRO1475 polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic...
|
|
|
7431932 |
Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions
Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with...
|
|
|
7429641 |
PRO9830 polypeptides
The present invention is directed to novel PRO9830 polypeptides chimeric polypeptide molecules comprising PRO9830 polypeptides fused to heterologous polypeptide sequences.
|
|
|
7417116 |
PRO7155 polypeptides
The present invention is directed to novel PRO7155 polypeptides and chimeric polypeptide molecules comprising PRO7155 polypeptides fused to heterologous polypeptide sequences.
|
|
|
7416893 |
Methods for diagnosing drug-resistant cancer cells or for identifying chemotherapeutic agents by measuring anomalous intracellular ion and/or second messenger dynamics
The present invention relates to methods of identifying drug-resistant and/or drug-sensitive cells, for example, breast cancer and brain tumor cells, on the basis of different ion and/or second...
|
|
|
7416699 |
Carbon nanotube devices
Nanotubes and nanotube-based devices are implemented in a variety of applications. According to an example embodiment of the present invention, a nanotube is adapted to pass current between two...
|
|
|
7412333 |
Method for prognostic factor analysis regarding cancers
A method for treating a patient with cancer includes the steps of obtaining cells from a cancerous tumor in the patient. Then there is the step of performing multiple correlated measurements on...
|
|
|
7411042 |
Tumor associated nucleic acids and uses therefor
The invention describes SAGE (sdph3.10) and sdp3.5 tumor associated nucleic acids, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments...
|
|
|
7408035 |
PRO9864 polypeptides
The present invention is directed to novel PRO9864 polypeptides and chimeric polypeptide molecules comprising PRO9864 polypeptides fused to heterologous polypeptide sequences.
|
|
|
7402656 |
PRO10013 polypeptides
The present invention is directed to novel PRO10013 polypeptides chimeric polypeptide molecules comprising PRO10013 polypeptides fused to heterologous polypeptide sequences.
|
|
|
7402403 |
Tumour markers
A method of determining the immune response of a mammal to circulating tumour marker proteins is described in which a sample of bodily fluid, for example plasma or serum, is contacted with a panel...
|
|
|
7402299 |
Intracorporeal medicaments for photodynamic treatment of disease
New intracorporeal photodynamic medicaments and certain medical uses and methods for use of such photodynamic medicaments for treatment of disease in human or animal tissue are described, wherein a...
|
|
|
7393685 |
Method for cultivating cancer cells from human tissue and device for preparing tissue samples
The invention relates to a method for cultivating cancer cells for scientific serial assays, wherein a tissue sample which is heterogeneous with respect to contaminants, normal cells and tumor...
|
|
|
7393656 |
Methods and compositions for risk stratification
The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of...
|
|
|
7390628 |
Microparticle-based diagnostic methods
The present invention concerns novel materials and methods to detect low frequency surface changes utilizing modified microspheres. Upon exposing the surface to the modified microspheres of the...
|
|
|
7384623 |
High energy phototherapeutic agents
High energy phototherapeutic agents or radiosensitizer agents comprised of a halogenated xanthene, or other related agents that exhibit a preference for concentration in biologically sensitive...
|
|
|
7381535 |
Methods and compositions for detecting receptor-ligand interactions in single cells
The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides...
|
|
|
7378233 |
BRAF mutation T1796A in thyroid cancers
The BRAF gene has been found to be activated by mutation in human cancers, predominantly in malignant melanoma. We tested 476 primary tumors, including 214 lung, 126 head and neck, 54 thyroid, 27...
|
|
|
7374936 |
Method and means for site directed therapy
The present invention relates to the field of site directed therapy. More specifically the invention relates to site directed radio therapy, and provides a method for production of radioconjugates...
|
|
|
7374886 |
Tissue inhibitor of matrix metalloproteinases type-1 (TIMP-1) as a cancer marker and postoperative marker for minimal residual disease or recurrent disease in patients with a prior history of cancer
The present invention describes a method for determining whether an individual is suffering from cancer by determining a parameter representing the TIMP-1 concentration in body fluid samples from...
|
|
|
7371562 |
Guided mode resonant filter biosensor using a linear grating surface structure
Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also...
|