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7585641 Immunoassay and method of use  
A method for performing an immunoassay is described. The method is particularly useful for detecting extracellular polysaccharide (EPS) and/or lipopolysaccharide (LPS) producing microorganisms. The...
7572642 Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns  
The invention provides a particle comprising a surface, wherein a portion of the surface is capable of emitting electromagnetic radiation and another portion of the surface is capable of emitting a...
7560238 Immunological latex turbidimetry method and reagent therefor  
An immunological latex turbidimetry method for analyzing an antigen or antibody in a sample is disclosed, comprising steps of (1) bringing a sample which may contain the antigen or antibody to be...
7553675 Diagnostic assay device having an apparent non-signal line  
A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or...
7537907 Products and methods for single parameter and multiparameter phenotyping of cells  
A method of single parameter and multiparameter characterizing of cells, particularly immunophenotyping of cells, is provided. The method preferably uses antibody coated microspheres which are...
7524641 Method of separating cells from a sample  
Rare cells are separated from a sample fluid by a positive selection or negative selection antibody by centrifuging in a tube containing a harvesting float. The harvesting float has an axial...
7521260 Assay test strips and reading same  
An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker...
7521259 Assay test strips with multiple labels and reading same  
In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a...
7494824 Interactive system for presenting and eliminating substances  
An interactive system is provided with at least one active surface of plastic from monomers containing at least one structural element derived from a carbon dioxide (A), and at least one substance...
7494782 Assay for measuring factor viia-antithrombin complexes  
A method for determining the concentration of factor VIIa-antithrombin complexes is disclosed which has application to estimating the level of intravascular exposure of tissue factor, assessing...
7491551 Quantitative lateral flow assays and devices  
This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention...
7488608 Reduction of non-specific binding in assays  
Methods and compositions are disclosed for reducing non-specific binding in a binding assay for the determination of an analyte in a sample where one of the reagents for conducting the binding...
7432046 Methods for the determination of antibody IgG avidity  
The present invention relates to methods of determining anti-infectious agent IgG avidity, for example, human anti-cytomegalovirus and human anti-toxoplasma IgG avidity, using a competitive assay...
7393697 Diagnostic test for analytes in a sample  
Diagnostic devices and methods are provided. The diagnostic devices preferably comprise a test strip with a test area. The sample to be analyzed contacts the test area, which comprises a specific...
7390677 Immunoassay and immunoassay apparatus  
An immunoassay comprises the steps of: (a) mixing a whole blood sample with sensitized insoluble carrier particles smaller than erythrocytes to cause an immune agglutination reaction; (b)...
7390676 System and method for programmable illumination pattern generation  
A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution....
7338813 Carrier particle latex for assay reagent and assay reagent  
An objective of the invention is to provide a carrier particle latex for an assay reagent capable of assaying a biological sample at a wide range of the concentration in an immunoserological test...
7335401 Method for producing microparticles loaded with proteins  
The present invention concerns a method for producing microparticles loaded with proteins which is characterized in that the microparticles are loaded in suspension under strongly alkaline...
7332344 Luminescence assays  
A method of detecting an analyte is described in which an up-converting luminescent species that is excited by absorption of long wavelength light is provided as a donor of energy to an acceptor...
7332288 Methods and reagents for the rapid and efficient isolation of circulating cancer cells  
A highly sensitive assay is disclosed which combines immunomagnetic enrichment with multiparameter flow cytometric and immunocytochemical analysis to detect, enumerate and characterize carcinoma...
7326578 Urine assay for ovarian reserve  
It has been found that a urine test for ovarian reserve can be provided which is equivalent in sensitivity to current laboratory methods which determine ovarian reserve based on FSH levels in...
7306949 Combination of CRP and D-dimer for in vitro diagnosis of deep venous thrombosis (DVT)  
The present invention relates to an in vitro diagnostic method for patients with suspected deep venous thrombosis wherein by combined testing of patients' samples for D-dimer and CRP both the...
7297554 Immunoassay system  
A competitive immunoassay, dye and method for rapidly detecting the presence of one or more target ligands within a fluid sample suspected of containing such ligand or ligands. The immunoassay...
7285424 Membrane-based assay devices  
A membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes a self-calibrated magnetic binding assay format (e.g.,...
7279340 Synthesis and application of procainamide analogs for use in an immunoassay  
The present invention relates to immobilized procainamide analogs, as well as to a method of making immobilized procainamide analogs. These immobilized analogs are prepared by activating the...
7267940 HSV-2 type-specific immunoassays using glycoprotein G2 peptides  
The present invention relates to peptides that are derived from HSV-2 glycoprotein G2 and represent HSV-2 type-specific epitopes. The present invention also provides for compositions comprising...
7262063 Directed assembly of functional heterostructures  
The present invention relates to a systematic process for the creation of functionally organized, spatially patterned assemblies polymer-microparticle composites including the AC electric...
7244391 Apparatus and method for the manipulation and testing of molecules, and in particular of DNA  
An apparatus for manipulating and testing molecules includes a surface to which the molecule is anchored at multiple points at one end, a paramagnetic bead on which said molecule is anchored at...
7229842 Metal chelate containing compositions for use in chemiluminescent assays  
Compositions are disclosed comprising (a) a metal chelate wherein the metal is selected from the group consisting of europium, terbium, dysprosium, samarium osmium and ruthenium in at least a...
7229835 Amine detection method and materials  
A compound linked to a solid support (R) through a divalent linker moiety (X) and which is represented by the following formula: is disclosed. In particular, the...
7208299 Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces  
The present invention is directed to a composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces and hydrophobic coated surfaces. The composition is a...
7208281 Ligands used for detecting prions  
The invention relates to the use of specific ligand carriers for detecting prions, and to substances that are capable of binding to prions and that are subsequently used to detect prions.
7205162 Artificial antibodies, method of producing the same and use thereof  
Artificial antibodies or antibody mimics are described. They consist of polymers that carry specific binding sites mimicking the properties of antibodies. There is also described a method for...
7192786 Biospecific assay method  
This invention relates to a biospecific assay method, in which microparticles coated with the bioaffinity reactant A binding the analyte to be assayed; the sample to be analyzed, and the labelled...
7192724 Method for differentiating irritable bowel syndrome from inflammatory bowel disease (IBD) and for monitoring persons with IBD using total endogenous lactoferrin as a marker  
A method for aiding in differentiating irritable bowel syndrome from inflammatory bowel disease by determining the level of total endogenous human lactoferrin in clinical specimens, such as feces,...
7179660 Carriers coated with polysaccharides, their preparation and use  
A polysaccharide coated carrier having a coating of at least two successive layers of polysaccharide. The first polysaccharide layer spontaneously associates with a second polysaccharide layer and,...
7179611 Mono-specific polyclonal antibodies and methods for detecting Clostridium difficile Toxin A  
A method is provided for the purification of Clostridium difficile Toxin A antigen comprising reacting impure Toxin A with immobilized mono-specific polyclonal antibodies. The polyclonal...
7176036 Electroactive microspheres and methods  
Methods and devices for electrochemical detection of a specific binding pair member utilizing a microsphere with an incorporated electroactive marker, wherein a member of the specific binding pair...
7166476 Highly reproducible agglutination immunoassay method and reagents  
The present invention provides an agglutination immunoassay, wherein the agglutination of insoluble carrier particles such as latex are stabilized and uniformized to give good reproducibility, and...
7160735 Tagged microparticle compositions and methods  
Compositions and methods are disclosed for detecting multiple target analytes in a sample using microparticles having molecular tags attached by cleavable linkages. Generally, an assay mixture is...
7144742 Quantitative lateral flow assays and devices  
This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention...
7052650 Apparatus and method for the manipulation and testing of molecules, and in particular of DNA  
Apparatus for the manipulating and testing of molecules and in particular of DNA comprising a surface on which the molecule is anchored on multiple points at one end and a paramagnetic bead on...
7045363 Nucleic acid-bound polypeptide method of producing nucleic acid-bound polypeptide and immunoassay using the polypeptide  
A nucleic acid-bound polypeptide produced by binding a nucleic acid to a polypeptide, a method of producing the nucleic acid-bound polypeptide, and applications of the nucleic acid-bound...
7026166 Fluorogenic dyes  
The present invention relates to the use of fluorogenic or chromogenic dyes as reporter molecules for detecting cell entry by a specific molecule.
7005292 Device and method for the detection of an analyte utilizing mesoscale flow systems  
Disclosed are devices for detecting the presence of a preselected analyte in a fluid sample. The devices comprise a substrate microfabricated to define a sample inlet port, and a mesoscale flow...
6991912 Systems and methods for performing magnetic chromatography assays  
Novel magnetic assay methods and systems. According to a preferred embodiment, a chromatographic medium, which preferably comprises a test strip, is provided that is designed to be contacted with a...
6967107 N-aryl-carbamic acid ester-derived and valeric acid ester-derived cross-linkers and conjugates, and methods for their synthesis and use  
The present invention describes carbamic acid ester-derived and valeric acid ester-derived polyfunctional cross-linker molecules, and methods for their synthesis and use. The inclusion of polymeric...
6951716 Anti-platelet immunoglobulin bead positive control  
Immunoassay methods and apparatus are provided which utilize flow cytometry, coated latex microspheres, and fluorochrome labeled antibodies, to simultaneously detect the presence and amount of one...
6933106 Platelet immunoglobulin bead suspension and flow cytometry  
Immunoassay methods and apparatus are provided which utilize flow cytometry, coated latex microspheres, and fluorochrome labeled antibodies, to simultaneously detect the presence and amount of one...
6927071 Method for reducing non-specific aggregation of latex microparticles in the presence of serum or plasma  
A particle-enhanced assay for determining an analyte in a test sample in which an additive for reducing non-specific particle aggregation is added in an amount to substantially reduce non-specific...