Match Document Document Title
7629133 Controlled transport through multiple reversible interaction point membranes  
A method for causing a membrane to become permeable to a first chemical species, in which the membrane is contacted with a solution comprising a second chemical species. The membrane comprises a...
7618829 Method of detecting multiple analytes  
The invention relates to a a microtiter plate and its use in a method of the invention, which microtiter plate comprises a plurality of containers, wherein the bottom of each container comprises a...
7615339 Method for producing a colorimetric resonant reflection biosensor on rigid surfaces  
The invention provides methods for fabricating calorimetric resonant reflection biosensors.
7615376 Masking background fluorescence and luminescence in the optical analysis of biomedical assays  
In a process for the quantitative optical analysis of fluorescently labelled biological cells 5 , a cell layer on a transparent support at the bottom 2 of a reaction vessel 1 is in contact...
7604956 Supersensitive immunoassays  
An assay exhibiting improved sensitivity for achieving a factor of ten times (10×) better sensitivity than current sensitivity levels achieved by prior-art immunoassays, as exemplified by ELISA....
7582488 Gel-shell beads with adsorbed or bound biomolecules  
Disclosed are gel-coated beads (including Hydrogel™-coated beads), which are capable of adsorbing, or absorbing, proteins and other biomolecules onto or into the gel coating. The gel-coated beads...
7579195 Simple membrane assay method and kit  
The present invention is to provide a simple membrane assay method for detecting or quantitating an analyte in a specimen sample using an assay device equipped with a membrane bound with a...
7575939 Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements  
Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also...
7572642 Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns  
The invention provides a particle comprising a surface, wherein a portion of the surface is capable of emitting electromagnetic radiation and another portion of the surface is capable of emitting a...
7547557 Directed-flow assay device  
A diagnostic assay device that directs an applied sample to the analytical membrane of a directed flow device. The device has a sample receiving port defined by layers of built-up material on one...
7541160 ELISA for VEGF  
The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions,...
7527939 Polyclonal-monoclonal ELISA assay for detecting N-terminus proBNP  
A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are...
7507588 Multiplex microparticle system  
Arrays of microparticle populations, each population labeled with a single fluorescent dye, are provided for use in multiplex assays. The populations form a virtual multidimensional array wherein...
7507550 Analytical sandwich test for determining NT-proBNP  
The present invention concerns an immunological test for determining NT-proBNP comprising at least two antibodies to NT-proBNP, wherein at least one of the antibodies to NT-proBNP is a monoclonal...
7494824 Interactive system for presenting and eliminating substances  
An interactive system is provided with at least one active surface of plastic from monomers containing at least one structural element derived from a carbon dioxide (A), and at least one substance...
7494782 Assay for measuring factor viia-antithrombin complexes  
A method for determining the concentration of factor VIIa-antithrombin complexes is disclosed which has application to estimating the level of intravascular exposure of tissue factor, assessing...
7470540 Method and device for the integrated synthesis and analysis of analytes on a support  
A method for preparing receptor-coated particles is described which comprises the following steps: a) providing a support body, b) conducting a liquid containing particles into or onto the support...
7459315 Miniaturized assembly and method of filling assembly  
A miniaturized assembly is provided whereby a fluid sample can be divided into a plurality of sample portions in retaining wells and the sample fluid can be displaced from open ends of the wells...
7449329 Blood test kit  
A blood crossmatching apparatus, kit and methods for testing the compatibility of mammals for blood transfusion. Particulate layers in the apparatus allow nonagglutinated red blood cells to...
7442553 Method for determining the amount of the maleimidyl groups of a particle  
A method for quantitatively determining the amount of maleimidyl groups on a polymer fine particle containing at least maleimidyl groups, by allowing a fluorescent material having an SH group to...
7402381 Method of immobilizing molecules onto a solid phase substrate and method of fabricating a biosensor using the method  
Aspects of the invention can provide a method capable of easily realizing immobilization with the optimum density derived from a concentration control and without phase separation in coadsorption...
7393698 Magnetic fine particles and process for producing the same  
The present invention relates to magnetic fine particles having immobilized thereto a polymer having an upper critical solution temperature, and a process for producing the same, a method of...
7393696 Bovine pregnancy test  
This invention provides bovine pregnancy test methods and devices. The test is also suitable for other ruminant and/or ungulate animals. Antigens from Group A (early pregnancy antigens), and/or...
7390461 Broad spectrum optically addressed sensor  
The present invention relates to a sensor for detecting chemical, biological, biochemical or other environmental stimuli, and includes a plurality of colloidal particles having chemical receptors...
7384779 Porous substrate plates and the use thereof  
A substrate plate or device adapted for use with biological or chemical assays is disclosed. The device may take the form of a multi-well plate having a three-dimensional, porous layer as part of a...
7381552 Macroporous material in the form of plastic pearls  
The invention relates to a macroporous plastics bead material with an average particle diameter from 10 to 1000 μm, containing a copolymer of a) 5-60 wt. % vinylically polymerizable monomers with...
7368296 Solid phases optimized for chemiluminescent detection  
Solid supports for chemiluminescent assays are provided. The solid support includes a plurality of probes covalently or physically attached to the support surface and a chemiluminescent enhancing...
7364918 Colorimetric sensors constructed of diacetylene materials  
Colorimetric sensors comprising a receptor incorporated within polydiacetylene assemblies to form a transducer capable of indicating a color change when contacted with an analyte are disclosed....
7344848 Methods for determining adequacy of heat processing of a cooked meat sample  
Monoclonal antibodies are provided which bind to heat-treated proteins of meats. The antibodies are useful in detecting the presence of an exogenous meat in a cooked or raw meat sample....
7338813 Carrier particle latex for assay reagent and assay reagent  
An objective of the invention is to provide a carrier particle latex for an assay reagent capable of assaying a biological sample at a wide range of the concentration in an immunoserological test...
7329484 Retentate chromatography and protein chip arrays with applications in biology and medicine  
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity...
7326578 Urine assay for ovarian reserve  
It has been found that a urine test for ovarian reserve can be provided which is equivalent in sensitivity to current laboratory methods which determine ovarian reserve based on FSH levels in...
7319032 Non-sugar sweeteners for use in test devices  
The present invention provides methods, compositions, and kits for rapid detection of analytes in a sample. Surprisingly, it has been found that bulking materials having non-sugar sweeteners...
7314749 Method and apparatus for assay based on light diffraction  
The present invention relates to a method and apparatus for detecting analytes in a medium, and more particularly the present invention relates to an assay based on light diffraction which appears...
7309723 Redox polymer nanoparticles  
The invention provides nanoparticles comprising one or more redox-active species, methods of making such nanoparticles, and methods for using such nanoparticles, for example, as diagnostic agents...
7291477 Method and device for trichomonas detection  
A method and kit for detecting Trichomonas vaginalis infection in a human subject are disclosed. In the method, a body-fluid sample such as a vaginal swab sample or urine is obtained from the...
7288415 Compositions and methods for capturing, isolating, detecting, analyzing and quantifying macromolecules  
The present invention provides imprint compositions useful for capturing, isolating, detecting and/or quantifying macromolecules in a sample, methods of making and using the same. Generally, the...
7285424 Membrane-based assay devices  
A membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes a self-calibrated magnetic binding assay format (e.g.,...
7264939 Method of detecting native proBNP  
The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the...
7247489 Ion-detecting microspheres and methods of use thereof  
This invention provides methods of using ion-detecting microspheres containing an ionphore and a chromoionphore in clinical laboratory instrumentation such as flow cytometry for sample analysis. In...
7247500 Reduction of the hook effect in membrane-based assay devices  
A membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes a chromatographic zone on which is disposed a plurality...
7238536 Controlled transport through multiple reversible interaction point membranes  
A membrane comprising two or more macromolecules that interact via multiple reversible physical interaction points (MRIPM). The membrane further comprises a chemical species A, which interacts...
7232661 Diagnostic agents for the prenatal diagnosis of preterm delivery, fetal infection, and fetal damage, and diagnostic kit containing the same  
This invention is about a method for the prenatal diagnosis of preterm delivery, fetal infection, and fetal damage, and diagnostic reagent system and diagnostic kit for the diagnosis. The method,...
7229835 Amine detection method and materials  
A compound linked to a solid support (R) through a divalent linker moiety (X) and which is represented by the following formula: is disclosed. In particular, the...
7229771 Polyethylene glycol-derivatized biomolecules and their use in heterogeneous detection methods  
The use of polyalkylene oxide modified reagents is disclosed in a method for the detection of an analyte or in suitable reagent kits for such methods.
7229840 Surfaces comprising a hydrophilic spacer, covalently bonded to hydrogels  
The object with the funtionalized hydrogel surface for detection of analyte molecules is obtainable by a process including (1) providing a hydrogel layer on a base surface; (2) bonding organic...
7226753 Displacement assay for selective biological material detection  
The present invention relates to displacement assay type bioassay materials useful for the detection of toxic substances and, more particularly, to packaging materials for food and other products,...
7223534 Diffraction-based diagnostic devices  
A biosensor includes a substrate with a layer of receptive material disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the...
7217575 Avidin derivatives and uses thereof  
A covalent conjugate of a 4′-hydroxyazobenzene-2-carboxylic acid derivative (HABA) and an avidin-type molecule, of the formula: wherein A is (CH 2 ) n or —CH═CH—, wherein n is an...
7214546 Dendritic chemiluminescent substrates  
Chemiluminescent substrate delivery systems comprising a conjugate of a dendrimer and at least one chemiluminescent substrate are provided. The substrate delivery systems can also include a...