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8809005 Conjugate and its use as a standard in an immunoassay  
A composition comprising a conjugate of an anti-idiotype antibody specifically binding to a CDR region of a parent antibody and method of using polyclonal human serum immunoglobulin of class E, G,...
8679858 Lanthanide mass dots: nanoparticle isotope tags  
Compositions and methods are provided for the use of nanoparticles, which may be referred to herein as mass dots, as mass tags for probes such as antibodies, aptamers, nucleic acids, etc. in...
8663985 Anchoring/capturing system for selecting or analyzing a CHO cell according to a product secreted by the CHO cell  
An anchoring/capturing system for selecting or analyzing a CHO cell according to a product secreted by the CHO cell is described. The anchoring/capturing system comprises a first antibody or a...
8642275 Immunological tests for the presence of bacteria which make use of antibodies obtained using a specific method  
The use of a bacterial antigen obtained from bacterial cells in the production of antibodies for immunological assays for detecting bacterial cells.
8518653 Detection of cannabis use  
A binding partner, especially an antibody fragment that specifically recognizes an antigen-antibody immune complex between anti-THC and THC (tetrahydrocannabinol), is disclosed. The binding partner...
8501427 Factor H polymorphisms in the diagnosis and therapy of inflammatory diseases such as age-related macular degeneration  
The invention relates to antibodies, including monoclonal and polyclonal, or fragments thereof, which discriminate between the histidine and tyrosine isoforms of Complement Factor H and to their...
8486645 Gene defects and mutant ALK kinase in human solid tumors  
Novel gene deletions and translocations involving chromosome 2 resulting in fusion proteins combining part of Anaplastic Lymphoma Kinase (ALK) kinase with part of a secondary protein have now been...
8486657 Anti-preproprotein and anti-preprotein antibodies as immunohistochemical markers  
It is disclosed herein that antibodies specific for preproproteins or preproteins, which are synthesized by certain types of cells or tissues, can be used in immunohistochemistry assays to...
8476082 Device for detection of target molecules and uses thereof  
Devices and methods for the detection of target molecules are disclosed. Devices and methods for detecting food-borne target molecules are also disclosed.
8476027 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Detection of cannabis use
 
A binding partner, especially an antibody fragment that specifically recognizes an antigen-antibody immune complex between anti-THC and THC (tetrahydrocannabinol), is disclosed. The binding partner...
8470793 Down-regulation of mortalin by siRNA  
Use of a siRNA molecule selected from the group consisting of SEQ ID NO: 173 to 344 for treating a disease associated with a pathological cell population in a subject in need thereof is disclosed....
8409568 Mutant antibody Fc domains and fusion proteins thereof  
The present invention relates to a viral vector encoding for a library of antibodies or antibody fragments that are displayed on the cell membrane when expressed in a cell. The present invention...
8404820 Human monoclonal antibodies against Bacillus anthracis protective antigen  
Isolated human monoclonal antibodies which bind to Anthrax protective antigen are disclosed. The human antibodies can be produced in a non-human transgenic animal, e.g., a transgenic mouse, capable...
8383350 Assay for detection of IL-10 antibodies  
Provided are assays to measure the presence and quantity of an antibody of interest in a patient's bloodstream or other biological sample. ECL and ELISA methods, and kits for such assays, as well...
8367356 Gelsolin binding agent compositions and uses of same  
The invention relates generally to gelsolin binding agents (e.g., antibodies) which can bind to gelsolin polypeptides. Gelsolin binding agents of the invention are useful, alone or in combination,...
8349611 Resonant sensors and methods of use thereof for the determination of analytes  
Resonant sensors, preferably having floating bilayer symmetry, and their methods of use is determining the presence, amount or binding kinetics of an analyte of interest in a test sample are...
8329475 Wash process for removing undesired components in samples being analyzed  
A method for removing undesired component(s) from bound desired component(s) in an analysis including: (a) providing a container having a desired component bound thereto and an undesired component;...
8293716 Method of treating cancer by modulation of mortalin  
A method of treating cancer in a subject in need thereof is disclosed. The method comprises administering to the subject a siRNA molecule capable of inducing degradation of an mRNA encoding a...
8293542 Real time binding analysis of antigens on a biosensor surface  
The invention provides methods for detecting interactions between phage and antigen or antigen and antibody using biosensors.
8277808 Mucosal vascular addressins and uses thereof  
The present invention relates to isolated antibodies and antigen-binding fragments thereof that bind naturally occurring human MAdCAM, wherein said naturally occurring human MAdCAM comprises a...
8268637 Label-free biosensors based upon distributed feedback laser  
A biosensor based upon a vertically emitting, distributed feedback (DFB) laser is disclosed. In one configuration, the DFB laser comprises a replica-molded, one- or two-dimensional dielectric...
8263356 Antibodies and methods for predicting dental caries  
The present invention relates to antibodies, binding portions thereof, or probes that bind specifically to glucosyltransferase enzymes, and uses of these agents for detecting glucosyltransferase...
8247188 FAS binding antibodies  
The disclosed invention relates to monoclonal antibodies (MAbs) which recognize human fatty acid synthase (hFAS) and are distinct from previously known anti-hFAS antibodies. Compositions, devices...
8241883 High throughput mobility shift  
The present invention provides novel microfluidic devices and methods for performing pulsed field mobility shift assays in microfluidic devices. In particular the devices and methods of the...
8183056 Assay  
A method for determining the risk of an individual of suffering from inflammation, opportunistic infection or disruption of immunoglobulin metabolism, comprising (a) determining the level of...
8183059 Device for detection of target molecules and uses thereof  
Devices and methods for the detection of antigens are disclosed. Devices and methods for detecting food-borne pathogens are disclosed.
8182855 Fish food containing fermented soyfood  
The present invention relates to an enriched fish food product comprising a binder resin and a fermented soy nutraceutical. Optionally the nutraceutical may contain enzymes or coenzymes. Also, the...
8178358 Serpine2 as a biomarker for IgA nephropathy  
The present invention provides a method for diagnosis or prognosis of IgA nephropathy in a subject based on detection of the expression level of one or more biomarker genes selected from the group...
8173372 Methods of donor specific crossmatching  
The detection of endothelial cell antibodies has been proven clinically important for successful organ transplantation. Disclosed are methods of isolating Tie-2+ and CD34− precursor endothelial c...
8173130 Antibodies against flagellin and uses thereof  
The present invention provides a novel class of monoclonal antibodies which have a high affinity, broad spectrum neutralizing reactivity to flagellin from various Gram-negative bacteria including,...
8148170 Immunosensors: scFv-linker design for surface immobilization  
An apparatus and methods for binding an analyte of interest in a sample are provided. The apparatus comprises a substrate with an exposed surface with an compound, that is electrostatically charged...
8114617 Method for quantifying phosphokinase activity on proteins  
The invention involves a method for measuring phosphorylation of proteins at specific sites and, as such, is an indicator of the protein kinase activity of enzymes capable of phosphorylating those...
8114967 Constructs and libraries comprising antibody surrogate light chain sequences  
The invention concerns constructs and libraries comprising antibody surrogate light chain sequences. In particular, the invention concerns constructs comprising VpreB sequences, optionally...
8093010 Angiogenesis inhibiting molecules, their selection, production and their use in the treatment of cancer  
The present invention relates to a method for providing molecules that are capable of inhibiting angiogenesis, comprising the steps of providing a range of molecules; testing whether these...
8093012 Multiplex in situ immunohistochemical analysis  
A method of in situ immunohistochemical analysis of a biological sample is provided. The method allows for the multiplex and simultaneous detection of multiple antigens, including multiple nuclear...
8084272 Amelioration of heterophile antibody immunosensor interference  
The invention is directed to methods and devices for reducing interference from heterophile antibodies in an analyte immunoassay. In one embodiment, the invention is to a method comprising the...
8053226 Device and method for simultaneously identifying blood group antigens  
The invention relates to a device for simultaneously, qualitatively or quantitatively identifying a number of analytes in a liquid sample. The device comprises a membrane with: a charging zone for...
8048414 Antivenom composition containing Fab fragments  
F(ab) fragments are isolated from an antibody containing source by contacting the antibody containing source with a papain-polyacrylamide matrix to produce F(ab) and F(c) fragments which are then...
8039273 β-glucuronide-linker drug conjugates  
Ligand Drug conjugate compounds comprising a β-glucuronide-based linker and methods of using such compounds are provided.
8012762 Test device, and related methods  
Test device for detection and visual indication of a specific analyte in a liquid sample such as a body fluid. The device includes a biodegradable housing, a test strip and a lid. The device is...
8012770 Device for detection of antigens and uses thereof  
Devices and methods for the detection of antigens are disclosed. Devices and methods for detecting food-borne pathogens are disclosed.
7993865 Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen  
The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence or IgA anti-OmpC antibodies in the subject, where the presence of the IgA...
7994291 Human E3α ubiquitin ligase family  
The present invention relates to a novel polypeptide encoding a protein which is the full length human ortholog of E3α ubiquitin ligase. The invention also relates to vector, host cells, ...
7993867 Diagnosis, prevention and treatment of crohn's disease using the OmpC antigen  
The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence or IgA anti-OmpC antibodies in the subject, where the presence of the IgA...
7993866 Diagnosis, prevention and treatment of crohn's disease using the OmpC antigen  
The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence or IgA anti-OmpC antibodies in the subject, where the presence of the IgA...
7968283 Gene expressed in prostate cancer  
A novel testis-specific gene expressed in human prostate cancer, designated 22P4F11, is described. Analysis of 22P4F11 mRNA expression in normal prostate, prostate tumor xenografts, and a variety...
7939282 Methods for detecting sepsis  
Compositions and methods for detecting sepsis by contacting a subject-derived sample with a ligand that binds to GRK and determining the concentration of GRK in the sample. An increase in the...
7935520 Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements  
Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also...
7932048 Method for the in vitro diagnosis of alzheimer's disease using a monoclonal antibody  
The invention relates to a method for the in vitro diagnosis of Alzheimer's disease using a monoclonal antibody. Said antibody can bind at least to amino acids 12-16 of the β-amyloid peptide, ...
7919255 Assessment of skeletal growth using measurements of NT-CNP peptides  
A means of measuring and monitoring skeletal growth rate using a plasma analyte, amino-terminal C-type natriuretic peptide (NT-CNP). Plasma NT-CNP concentrations reflect the potential for further...
Matches 1 - 50 out of 447 1 2 3 4 5 6 7 8 9 >