Match Document Document Title
7993857 Determination of AM-binding proteins and the association of adrenomedullin (AM) therewith  
The present invention provides methods for the isolation, identification, and purification of adrenomedullin (AM)-binding proteins. Also, provided are methods for utilizing the purified AM-binding...
7993850 Method and probes for the detection of a tumor-specific fusion protein  
The invention relates to the detection of fusion proteins. Described are a set of at least a first and a second molecular probe, each probe provided with a dye wherein the dyes together allow...
7993858 Methods for predicting pregnancy outcome in a subject by hCG assay  
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present...
7993859 Method for quantifying oxidative stress caused by different biological pathways  
The present invention relates to methods for detecting a oxidative stress in a biological sample, methods of determining a cumulative record of oxidative injury, and methods of diagnosing diseases...
7993868 Saposin D and FAM3C are biomarkers for alzheimer's disease  
The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying Alzheimer's disease status in a patient. In particular, the biomarkers of this...
7993855 Use of additives to lower the rate of a binding reaction  
A method of lowering the rate of a specific binding reaction in an assay for the detection and/or measurement of an analyte of interest is provided herein. In particular, the method includes...
7993854 Detection and quantification of biomarkers via a piezoelectric cantilever sensor  
Quantification of a target analyte is performed using a single sample to which amounts of the target analyte are added. Calibration is performed as part of quantification on the same sample. The...
7989208 Gamma secretase notch biomarkers  
The present invention relates to the biomarker TFF-3 that measures γ-secretase mediated Notch processing. TFF-3 has utility in predicting and/or determining in vivo Notch-related toxicity...
7989216 Two helix binders  
An isolated polypeptide, Z domain, derived from B domain of Staphylococcal protein A, comprising a pair of anti-parallel alpha helices that are capable of binding a target, is provided herein....
7990488 Detecting interactions at biomimetic interfaces with liquid crystals  
A method of forming a liquid crystal device, includes: contacting an aqueous solution comprising a surfactant and a receptor molecule with a top surface of a liquid crystal. The liquid crystal is...
7985562 Method for the identification of a risk for a thrombogenic disorder by determining the TAFI-lle347 polymorphism  
The present invention is directed to a method identifying a risk for a thrombogenic disorder, to a method for selecting patients with a risk for a thrombogenic disorder, to a method for...
7985560 Methods and compositions for monitoring and risk prediction in cardiorenal syndrome  
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects. In particular, the invention relates to methods...
7981692 Immunoassays to detect diseases or disease susceptibility traits  
Disclosed are immunoassay methods for the diagnosis/prognosis of diseases and disease susceptibility traits associated with gene mutations that cause protein truncation or allelic loss. The levels...
7981690 Method of assaying antigen and kit to be used therein  
By using an antibody which is covalently bonded to a water soluble polymer as an antibody to be used in a competitive immunoagglutination assay in a homogeneous system, a protein antigen at a high...
7981623 Repressor of skeletal muscle differentiation, nucleic acids coding therefor and the use thereof in diagnosis and therapy  
Polypeptide sequences which play a part in the regulation of skeletal muscle differentiation, and nucleic acids coding therefor, and the use thereof in diagnosis and therapy are disclosed....
7981691 Two helix binders  
An isolated polypeptide, Z domain, derived from B domain of Staphylococcal protein A, comprising a pair of anti-parallel alpha helices that are capable of binding a target, is provided herein....
7977459 Adiponectin receptor and gene encoding the same  
The object is to isolate and identify human and mouse adiponectin receptors, to provide a novel protein having adiponectin binding ability, and to provide a screening method and screening kit for...
7977060 Mammalian sweet taste receptors  
The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of...
7977118 Two helix binders  
An isolated polypeptide, Z domain, derived from B domain of Staphylococcal protein A, comprising a pair of anti-parallel alpha helices that are capable of binding a target, is provided herein....
7977104 Methods for predicting pregnancy outcome in a subject by hCG assay  
The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present...
7972802 Lipoprotein-associated markers for cardiovascular disease  
The invention provides methods of screening a mammalian subject to determine if the subject is at risk to develop, or is suffering from, cardiovascular disease. The methods comprise detecting an...
7968306 Method for measuring activity of a specific fraction of albumin  
Methods of measuring the SFA and sPLA2 activities in a mammalian subject are provided. The methods include: providing a substrate comprising a fluorescently labeled carboxylic acid and a...
7968308 Isolating human antibodies  
The invention is drawn to a method of isolating human antibodies.
7960127 TRP8, a transient receptor potential channel expressed in taste receptor cells  
The present invention relates to the discovery, identification and characterization of a transient receptor potential channel, referred to herein as TRP8, which is expressed in taste receptor...
7960128 TRP8, a transient receptor potential channel expressed in taste receptor cells  
The present invention relates to the discovery, identification and characterization of a transient receptor potential channel, referred to herein as TRP8, which is expressed in taste receptor...
7960130 Method for activation of transient receptor potential cation channel, subfamily A, member 1 using acetaldehyde  
The present invention relates to a method for activation of TRPA1 (transient receptor potential cation channel, subfamily A, member 1) using acetaldehyde, more precisely a method for selecting a...
7955808 Bitter taste receptors  
The present invention relates to bitter-taste receptors and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or...
7956161 Interferons of rhesus and cynomolgus origin and uses thereof  
Disclosed are interferons of Rhesus and Cynomolgus origin and methods of production and use thereof.
7955804 Diagnostic method for brain damage-related disorders  
A brain damage-related disorder is diagnosed in a subject by detecting at least one polypeptide, or a variant or mutant thereof, selected from A-FABP, E-FABP, PGP 9.5, GFAP, Prostaglandin D...
7955810 Positive selection of serum proteins for proteomic analysis  
This invention relates to methods and kits for positive selection of species of interest based on peptide/protein sequence from a biological sample. The species of interest may be proteins and/or...
7955811 Method for diagnosing and distinguishing stroke and diagnostic devices for use therein  
A method for determining whether a subject has had a stroke and, if so, the type of stroke which includes analyzing the subject's body fluid for at least four selected markers of stroke, namely,...
7951545 Method for detecting lysosomal storage diseases  
A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay...
7951612 In situ heat induced antigen recovery and staining apparatus and method  
Contemplated herein is an automated microscope slide antigen recovery and staining apparatus and method that features a plurality of individually operable miniaturized pressurizable reaction...
7951548 IL-13 production inhibitor  
The present invention provides a screening method/screening kit for an IL-13 production inhibitor, which comprises using (a) a protein comprising the same or substantially the same amino acid...
7951613 Chaperonin 10 modulation of toll-like receptor-inducible cytokine and chemokine secretion  
Methods of use of Chaperonin 10 (Cpn10) are provided for regulating Toll-like receptor signaling and/or Toll-like receptor inducible immunomodulator secretion. Cpn10 negatively regulates Toll-like...
7947462 Methods for identifying Kremen polypeptide binding partners  
The present invention relates to a composition useful for the diagnosis and therapy of diseases associated with aberrant expression of the gene encoding the receptor Kremen 1 and/or Kremen 2 e.g....
7947500 Liquid crystalline substrates for culturing cells  
The present invention is directed to liquid crystalline substrates useful in the culture of cells and methods of their use. In certain embodiments, the invention provides methods and devices for...
7947443 DNA and RNA conformational switches as sensitive electronic sensors of analytes  
The electrical conductivity of DNA and other oligonucleotide constructs is dependent on its conformational state. Such a dependence may be harnessed for the electronic sensing of external...
7943328 Method and system for assisting in diagnosing irritable bowel syndrome  
The present invention provides methods, systems, and code for accurately classifying or diagnosing a sample from an individual as an IBS sample. The methods and systems of the present invention...
7943331 Whole blood assay  
A method and apparatus to estimate the concentration of a target substance (e.g. Cholesterol or CRP) in the plasma component of awhole blood sample without the need to separate the red blood cells...
7943330 Tailored glycoproteomic methods for the sequencing, mapping and identification of cellular glycoproteins  
The present disclosure relates to tailored glycoproteomic methods, and more particularly to methods for the sequencing, mapping and identification of cellular glycoproteins using...
7943301 DNA conformational switches as sensitive electronic sensors of analytes  
The electrical conductivity of DNA and other oligonucleotide constructs is dependent on its conformational state. Such a dependence may be harnessed for the electronic sensing of external...
7943394 Method and device for high sensitivity detection of the presence of DNA and other probes  
The present invention provides a method for capacitive detection of the presence of target sample on a substrate, which comprises the steps of: binding a target sample to selective binding sites...
7943327 Simultaneous assay of target and target-drug binding  
Whole cell, simultaneous target and drug-target assay using differentially labeled antibodies and flow cytometry. First antibody binds to total target and second antibody binds to the drug binding...
7943395 Extension of the dynamic detection range of assay devices  
A flow-through assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes multiple detection zones, one of which is premised on...
7943332 Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays  
The present invention relates to the field of immunology and hyperproliferative diseases. More specifically, the present invention relates to a method of detecting and monitoring therapeutic...
7939282 Methods for detecting sepsis  
Compositions and methods for detecting sepsis by contacting a subject-derived sample with a ligand that binds to GRK and determining the concentration of GRK in the sample. An increase in the...
7939280 Marker for inflammatory conditions  
Use of pregnancy-associated plasma protein-A as a marker for inflammatory conditions, and in particular, for acute coronary syndromes is described.
7939281 Method to identify patients at risk for lung transplant rejection  
Various embodiments include methods for diagnosing and treating medical conditions that involve an autoimmune response to connective tissue such as collagen found in organs such as the lung. In...
7939279 Mammalian T1R3 sweet taste receptors  
The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors, the receptors comprising consisting of a monomer or homodimer of a T1R3 G-protein coupled...