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8183046 |
Temperature resistant pH buffers for use at low temperatures
A method for preparing a composition that includes selecting a pH of the composition; selecting a first buffer with a negative temperature coefficient; selecting a second buffer with a positive...
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8163559 |
White blood cell differentiation reagent and method
A reagent for four-part differentiation of white blood cells is provided. In one embodiment the reagent has an osmolality below 50 mOsm/kg H2O. A method for differentiating white blood cells using...
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8148156 |
Synthetic urine and method for manufacturing synthetic urine
A synthetic urine solution is described. The synthetic urine solution is a shelf stable, food grade composition formed of water having a pH between 3 and 10. A thickening agent is dissolved within...
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8143064 |
Reagents and methods for classifying leukocytes
A reagent for classification of leukocytes includes (a) at least two cationic surfactants; (b) at least one organic compound bearing a hydrophobic group and an anionic group; (c) a buffer for...
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8137987 |
Simultaneous assay for determining drugs
Bodily fluid is analyzed for the presence of drugs of a selected panel of drugs in a simultaneous assay in which sample of the fluid is incubated with additional amounts of all drugs of the panel,...
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8105840 |
Urine pretreatment agent for urinary protein quantitation, urine pretreatment method, and urinary protein quantitation method
Described are a urine pretreatment agent, a urine pretreatment method, and a urinary protein quantitation method which reduce or cancel the influences of urine pH variations, cancel the influences...
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8080423 |
Reagent containing protease reaction promoter and/or colorant stabilizer
Stabilizers for colorants used for detection of enzymatic reactions, having a cyclodextrin and a catalase; reagents including stabilizers; and methods of use of such stabilizers and reagents.
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8071317 |
Methods for detection of hydrophobic drugs
Methods and reagents are disclosed for pretreating a sample suspected of containing a hydrophobic drug for conducting an assay method for detecting the hydrophobic drug. A combination is provided...
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8012753 |
Methods and compositions for regrowth of cryopreserved conifer embryos
The present invention provides methods for regrowth of conifer embryogenic cells. The methods comprise the steps of (a) contacting cryopreserved conifer embryogenic cells with a liquid transition...
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8003768 |
System for providing 20% ethanol solutions that meet bioburden and endotoxin requirements
A system and method for providing 20% ethanol solutions meeting bioburden and endotoxin specifications, which provides the 20% ethanol solution in a ready-to-use form which may be dispensed...
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8003402 |
Method for measuring the concentration of a glycosaminoglycan anticoagulant
The invention provides an accurate, economical, automatable, high throughput method for the determination of the concentration of glycosaminoglycan anticoagulants, including low molecular weight...
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7993850 |
Method and probes for the detection of a tumor-specific fusion protein
The invention relates to the detection of fusion proteins. Described are a set of at least a first and a second molecular probe, each probe provided with a dye wherein the dyes together allow...
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7981681 |
Method for the analysis of a blood sample, and apparatus and reagent for its implementation
Method for the automatic analysis of a blood sample in which: an analysis solution containing the blood sample, a diluent, and at least one compound to lyze the erythrocytes; at least one compound...
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7977156 |
Chipstack package and manufacturing method thereof
A method for manufacturing chip stack packages may include: providing at least two wafers, each wafer having a plurality of chips, and scribe lanes formed between and separating adjacent chips;...
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7947465 |
Simultaneous assay for determining drugs
Bodily fluid is analyzed for the presence of drugs of a selected panel of drugs in a simultaneous assay in which sample of the fluid is incubated with additional amounts of all drugs of the panel,...
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7943368 |
Reducing time to result for blood bank diagnostic testing
Methods for reducing time to result in blood bank diagnostic testing with an agitation device and a low ionic strength solution are disclosed. Specifically provided are methods for reducing...
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7919266 |
Method of detecting red cell antigen-antibody reactions
A process for the detection of antibodies in a test sample by preparing a suspension of erythrocytes with a test serum or plasma by mixing a test serum or plasma with erythrocytes; incubating the...
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7901950 |
Method for assessing disease states by profile analysis of isolated circulating endothelial cells
Elevated number of Circulating Endothelial Cells (CEC) have been implicated in disease conditions associated with the formation or destruction of blood vessels such as acute coronary syndrome,...
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7879612 |
Organic non-sugar compounds for protection of biologically active molecules and conjugate labels and methods of use thereof
Provided are methods comprising the use of non-sugar organic compatible solutes for protection and preservation of the activity of biologically active molecules and conjugate labels. The methods...
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7867765 |
Blood cell sorting methods and systems
The invention relates to methods of isolating white blood cells (WBCs) from a sample, e.g., whole blood, using magnetic particles that specifically bind to WBCs and a series of specific steps and...
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7837895 |
Supercooling promoting agent
During the investigation of the mechanism that cellular water in woody plants growing in cold districts keeps liquid state at low temperature, the inventors have studied to identify the causative...
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7824916 |
Sheath liquid for particle analyzer
A sheath liquid for a particle analyzer used to analyze particles contained in a sample is described. The sheath liquid includes water and a refractive-index adjustment agent with glycerols and/or...
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7803523 |
Whole blood preparation for cytometric analysis of cell signaling pathways
This invention is directed to a method for preparation of a biological sample for measurement of protein epitopes that allows for the preservation of intracellular protein epitopes and detection of...
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7790471 |
Metering technique for lateral flow assay devices
A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. A sample membrane is utilized having a collection region and a detection region, the...
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7767465 |
Reduction of platelet interference in plasma assay samples
The present invention relates to compositions for improving assay accuracy for plasma samples by decreasing or eliminating false results due to platelet interference. The compositions of the...
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7767436 |
Reducing time to result for blood bank diagnostic testing
Methods for reducing time to result in blood bank diagnostic testing with an agitation device and a low ionic strength solution are disclosed. Specifically provided are methods for reducing...
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7749522 |
Organ arrest, protection and preservation
The present invention relates to a method for arresting, protecting and/or preserving an organ which includes administering effective amounts of (i) a potassium channel opener or agonist and/or an...
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7732210 |
Multi-analyte reference solutions
The present invention provides a reference solution for use in instruments that determine hematocrit levels in biological samples by measuring the resistance and/or conductivity of the biological...
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7713742 |
Calibration gas delivery apparatus
A calibration gas generation method and apparatus for generating a selectively humidified calibration gas to a measurement probe includes a delivery conduit having a conduit inlet adapted to...
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7709258 |
High throughput assay for identifying compounds capable of modulating the proliferative status of stem cells
The present invention relates generally to high-throughput assay methods that determine the proliferative status of hematopoietic stem and progenitor cells. The present invention further relates to...
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7695973 |
Determination of glycated protein
The present invention provides methods for quantitation of glycated protein in a biological sample using a solid support matrix by making a first bound protein measurement total bound protein under...
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7674629 |
Method for improving chemiluminescent signal
The present invention is directed to compositions and methods for improving a chemiluminescent signal. In particular, a reaction buffer with an alkaline pH range of about 9 to 10 provides a maximal...
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7659122 |
Single population of simulated leukocyte granules, calibrators comprising the same and methods of preparing the same
Disclosed is a single population of simulated leukocyte granules prepared from mammalian whole white blood cells, which is useful in calibrators for a hematology analyzer, a calibrator which...
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7645594 |
Method of preparing assay sample for discriminating bacteria by flow cytometer
A method of staining bacteria comprises: working a polymethine dye on a sample in the presence of a substance capable of reducing nitrite ions to stain bacteria in the sample. A method of detecting...
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7638290 |
Reagent and process for the identification and counting of biological cells
The invention relates to a reagent and a process for the identification and counting of biological cells in a sample. This reagent comprises a cell lysing agent selected from at least one detergent...
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7618810 |
Metering strip and method for lateral flow assay devices
A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection...
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7618821 |
Simulated blood components and methods
A control and a cellular fraction for use therein and methods for making the same, including a first cellular component including a plurality of a first group of processed animal red blood cells...
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7598089 |
Methods and compositions for separating cells
The invention provides compositions and methods for cell separation. These reagents and techniques specifically agglutinate cells via surface antigen recognition and can be used to recover rare...
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7592179 |
Five-part differential white blood cell control and method for preparation of the same
The present invention provides a method for preparing a five-part differential white blood cell control and a white blood cell control prepared thereby. The white blood cell control obtained by the...
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7588942 |
Standard/reference/control for blood coagulation testing
A whole-blood-based substitute composition that is useful in coagulation assays as a standard, reference, control, calibrator, linearity verifier, or training material is prepared by combining a...
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7567072 |
Real-time monitoring of particles in semiconductor vacuum environment
An apparatus includes semiconductor processing equipment. A particle detecting integrated circuit is positioned in a vacuum environment, the particle detecting integrated circuit containing a...
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7560282 |
System for the internal qualitative and quantitative validation of marker indices
The present invention relates to the qualitative and quantitative validation of marker indices, especially for medical diagnosis and particularly for the determination of the growth fraction in a...
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7550298 |
Automated immunohistochemical and in situ hybridization assay formulations
Provided herein are reagents for use in an automated environment for cell conditioning of biological samples wherein the cells or tissues are predisposed for access by reagent molecules for...
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7531357 |
Preparation of platelet analogs
Erythrocytes from a vertebrate animal other than a human that have been size reduced and treated with a fixing agent by conventional methods to resemble human platelets are further treated to...
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7521244 |
Standard reference solutions
Standard reference materials and related methods are described for quality testing and calibration of instruments used for the qualitative and quantitative determination of hemoglobin and glycated...
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7485472 |
Simple method for quantitative measuring the adhesion of platelets ex vivo
The invention relates to measuring of the adhesion of platelets ex vivo. In this method, monodisperse polymer particles are added to blood, and the number of platelets in the blood are measured...
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7482162 |
Determination of vitamin D metabolite and displacement from plasma or serum binding proteins
We disclose methods for measuring vitamin D metabolite in plasma or serum samples. The methods comprise a step of adding to the plasma or serum samples a non-competitive displacement agent...
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7449337 |
Lytic reagent and method for leukocytes differential in whole blood
A lytic reagent composition and methods for differential analysis of leukocytes are disclosed. In embodiments, the analysis may utilize optical measurements in flow cytometry based hematology...
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7422903 |
Multi-analyte reference solutions
The present invention provides a reference solution for use in instruments that determine hematocrit levels in biological samples by measuring the resistance and/or conductivity of the biological...
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7416891 |
Reagent and method for classifying leucocytes
A reagent for classifying leucocytes, including: a) at least one of surfactant selected from a cationic surfactant, an amphoteric surfactant, and the combination thereof; b) an organic compound...
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