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8178397 Field effect transistor  
A field effect transistor including a gate insulation portion, an organic semiconductor portion, a source electrode and a drain electrode, wherein when a voltage is applied to the gate at 70° C. ...
8163559 White blood cell differentiation reagent and method  
A reagent for four-part differentiation of white blood cells is provided. In one embodiment the reagent has an osmolality below 50 mOsm/kg H2O. A method for differentiating white blood cells using...
8143064 Reagents and methods for classifying leukocytes  
A reagent for classification of leukocytes includes (a) at least two cationic surfactants; (b) at least one organic compound bearing a hydrophobic group and an anionic group; (c) a buffer for...
8114580 Simulation of normal fresh blood platelets for reference control  
The present invention provides for novel analogs of fresh human platelets for use in hematological instrument. Methods for preparing such analogs are also described.
8105840 Urine pretreatment agent for urinary protein quantitation, urine pretreatment method, and urinary protein quantitation method  
Described are a urine pretreatment agent, a urine pretreatment method, and a urinary protein quantitation method which reduce or cancel the influences of urine pH variations, cancel the influences...
8092758 Method, device and system for volumetric enumeration of white blood cells  
A sample acquiring device for volumetric enumeration of white blood cells in a blood sample comprises a measurement cavity for receiving a blood sample. The measurement cavity has a predetermined...
8084223 Detection of false results in assays  
Methods and reagents are disclosed for detecting a false result in an assay for determining a concentration of an analyte in a whole blood sample suspected of containing the analyte. The method...
8071317 Methods for detection of hydrophobic drugs  
Methods and reagents are disclosed for pretreating a sample suspected of containing a hydrophobic drug for conducting an assay method for detecting the hydrophobic drug. A combination is provided...
8062860 Kit for measuring in vivo mutation frequency at an endogenous gene locus  
The present invention relates a method for the enumeration of in vivo gene mutation. The method utilizes differential staining of GPI-anchor deficient erythrocyte populations to distinguish between...
8048681 Methods for nucleic acid isolation and instruments for nucleic acid isolation  
The present invention relates to a technique for efficient isolation of long nucleic acids and short nucleic acids from a sample containing long nucleic acids and short nucleic acids via safe and...
8043859 Quality control mixture for glycine tablets, a method for preparing the mixture and a method for identifying the mixture  
A method is described for preparing a mixture for quality control of 0.1 g glycine tablets for sublingual application. The mixture for quality control includes a 100:0.5 ratio of ethanol to...
8029978 Processing method for the long-term stabilization of biological red blood cell volume  
The present invention relates to a processing method for long-term stabilization of biological red blood cell volume. The red blood cells can be further used in reference materials and calibrators...
8012757 Method for producing standard sample for use in quantitative determination of red phosphorus in resin  
Provided are a method for preparing a standard sample in which a uniform dispersion of a predetermined concentration of red phosphorus is guaranteed even in a very small amount, and an analytical...
7999084 Devices and methods for reducing matrix effects  
Devices and methods are provided for reducing matrix effects in protein precipitated bioanalytical samples comprising: a support, and a sorbent associated with the support capable of binding matrix...
7981681 Method for the analysis of a blood sample, and apparatus and reagent for its implementation  
Method for the automatic analysis of a blood sample in which: an analysis solution containing the blood sample, a diluent, and at least one compound to lyze the erythrocytes; at least one compound...
7968279 Reference control for cell by cell analysis  
A reference control for cell by cell analysis on flow cytometric analyzers contains cellular analogs made of permeated blood cells containing therein aggregated intracellular proteins and preserved...
7943385 Methods for assaying percentage of glycated hemoglobin  
The invention provides enzymatic methods for direct determination of percentage of glycated hemoglobin in blood samples without the need of a separated measurement of total hemoglobin content in...
7943368 Reducing time to result for blood bank diagnostic testing  
Methods for reducing time to result in blood bank diagnostic testing with an agitation device and a low ionic strength solution are disclosed. Specifically provided are methods for reducing...
7943118 Aerosolized fosfomycin/aminoglycoside combination for the treatment of bacterial respiratory infections  
A fosfomycin plus tobramycin combination formulation for delivery by aerosolization is described. The concentrated fosfomycin tobramycin combination formulation containing an efficacious amount of...
7919266 Method of detecting red cell antigen-antibody reactions  
A process for the detection of antibodies in a test sample by preparing a suspension of erythrocytes with a test serum or plasma by mixing a test serum or plasma with erythrocytes; incubating the...
7910378 Methods for detection of hydrophobic drugs  
Methods and reagents are disclosed for pretreating a sample suspected of containing a hydrophobic drug for conducting an assay method for detecting the hydrophobic drug. A combination is provided...
7901950 Method for assessing disease states by profile analysis of isolated circulating endothelial cells  
Elevated number of Circulating Endothelial Cells (CEC) have been implicated in disease conditions associated with the formation or destruction of blood vessels such as acute coronary syndrome,...
7855079 Methods for assaying percentage of glycated hemoglobin  
The invention provides enzymatic methods for direct determination of percentage of glycated hemoglobin in blood samples without the need of a separated measurement of total hemoglobin content in...
7824874 Method for measuring in vivo mutation frequency at an endogenous gene locus  
The present invention relates a method for the enumeration of in vivo gene mutation. The method utilizes differential staining of GPI-anchor deficient erythrocyte populations to distinguish between...
7803523 Whole blood preparation for cytometric analysis of cell signaling pathways  
This invention is directed to a method for preparation of a biological sample for measurement of protein epitopes that allows for the preservation of intracellular protein epitopes and detection of...
7799579 Method and device for processing a biological fluid for analyte determination  
The present invention refers to a method of processing a biological fluid which comprises cellular components by heat treatment. The method is particularly useful for preparing biological samples...
7790461 Nano-emulsion technology for drug elution  
Embodiments of the invention provide to apparatuses and media used in drug elution studies and methods for making and using them. One embodiment of the invention is a drug elution method that can...
7790471 Metering technique for lateral flow assay devices  
A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. A sample membrane is utilized having a collection region and a detection region, the...
7767465 Reduction of platelet interference in plasma assay samples  
The present invention relates to compositions for improving assay accuracy for plasma samples by decreasing or eliminating false results due to platelet interference. The compositions of the...
7767436 Reducing time to result for blood bank diagnostic testing  
Methods for reducing time to result in blood bank diagnostic testing with an agitation device and a low ionic strength solution are disclosed. Specifically provided are methods for reducing...
7745219 Reagent composition for the analysis of residual white blood cells in leuko-reduced blood banking products  
The enumeration and analysis of residual white blood cells in a sample of leukocyte-reduced blood products is conducted by forming a suspension of the leukocyte-reduced blood products with a...
7718387 Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays  
The present invention relates to the field of immunology and hyperproliferative diseases. More specifically, the present invention relates to a method of detecting and monitoring therapeutic...
7713688 Methods and compositions for depleting specific cell populations from blood tissues  
The invention provides compositions and methods for cell separation. These reagents and techniques specifically agglutinate cells via surface antigen recognition and can be used to recover even...
7678578 Cell permeabilization and stabilization reagent and method of use  
A cell permeabilization and stabilization reagent and method of use are disclosed. The reagent contains a N-acyl sarcosine or a salt thereof, a pH adjusting agent to adjust pH of the reagent in a...
7678574 Sensitivity controls for blood serology prepared from modified cells  
The invention provides for a process for preparing a sensitivity control for blood group determination including dissolving an amount of an antigen in water to give an antigen solution of known...
7674598 Method for a fully automated monoclonal antibody-based extended differential  
Methods for differentially identifying cells in an instrument employ compositions containing a combination of selected antibodies and fluorescent dyes having different cellular distribution...
7674622 Method for determination of nucleated red blood cells and leukocytes in a whole blood sample in an automated hematology analyzer  
A method for enumerating white blood cells and nucleated red blood cells. The steps of the method are as follows: (a) providing a lysed sample of whole blood;(b) introducing the lysed sample to a...
7659122 Single population of simulated leukocyte granules, calibrators comprising the same and methods of preparing the same  
Disclosed is a single population of simulated leukocyte granules prepared from mammalian whole white blood cells, which is useful in calibrators for a hematology analyzer, a calibrator which...
7638290 Reagent and process for the identification and counting of biological cells  
The invention relates to a reagent and a process for the identification and counting of biological cells in a sample. This reagent comprises a cell lysing agent selected from at least one detergent...
7632683 Method, apparatus, reagent kit and reagent for distinguishing erythrocytes in a biological specimen  
A method for distinguishing erythrocytes in a biological specimen, includes preparing a sample liquid so as to cause damage to a cell membrane of yeast-like fungi without hemolyzing erythrocytes in...
7632686 High sensitivity quantitation of peptides by mass spectrometry  
The instant invention provides an economical flow-through method for determining amount of target proteins in a sample. An antibody preparation (whether polyclonal or monoclonal, or any equivalent...
7625757 Reagent for immature leukocyte analysis and reagent kit  
A reagent for analyzing immature leukocyte capable of analyzing accurately immature leukocyte such as myeloblast and immature granulocyte, and mature leukocyte, which reagent has broader allowable...
7618810 Metering strip and method for lateral flow assay devices  
A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection...
7618821 Simulated blood components and methods  
A control and a cellular fraction for use therein and methods for making the same, including a first cellular component including a plurality of a first group of processed animal red blood cells...
7598089 Methods and compositions for separating cells  
The invention provides compositions and methods for cell separation. These reagents and techniques specifically agglutinate cells via surface antigen recognition and can be used to recover rare...
7595199 Method of detecting amyloid-like fibrils or protein aggregates  
The present invention relates to methods of detecting the presence of detergent- or urea-insoluble amyloid-like fibrils or protein aggregates on filters. Preferably, said fibrils or aggregates are...
7592179 Five-part differential white blood cell control and method for preparation of the same  
The present invention provides a method for preparing a five-part differential white blood cell control and a white blood cell control prepared thereby. The white blood cell control obtained by the...
7588942 Standard/reference/control for blood coagulation testing  
A whole-blood-based substitute composition that is useful in coagulation assays as a standard, reference, control, calibrator, linearity verifier, or training material is prepared by combining a...
7567072 Real-time monitoring of particles in semiconductor vacuum environment  
An apparatus includes semiconductor processing equipment. A particle detecting integrated circuit is positioned in a vacuum environment, the particle detecting integrated circuit containing a...
7550298 Automated immunohistochemical and in situ hybridization assay formulations  
Provided herein are reagents for use in an automated environment for cell conditioning of biological samples wherein the cells or tissues are predisposed for access by reagent molecules for...
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