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7632461 |
In situ heat induced antigen recovery and staining apparatus and method
An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of...
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7629173 |
Optical reader system and method for monitoring and correcting lateral and angular misalignments of label independent biosensors
An optical reader system and method are described herein that can detect a lateral and/or angular misalignment of one or more biosensors so that the biosensors can be properly re-located after...
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7629165 |
Diagnostic device and method
A method of separating a cell-containing sample into a substantially cell-depleted portion, and a cell-containing portion comprising at least one of a stem cell, a lymphocyte, and a leukocyte...
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7629175 |
Test element with a one layer reaction film
The invention concerns test elements and methods for the optical detection of an analyte in a sample. The test element includes a support having at least one transparent portion, and a one-layer...
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7625760 |
Analyzing cartridge and liquid feed control device
An analyzing cartridge and method for using it to analyze a sample having a plurality of reservoirs and capillaries connected for communication between these reservoirs and is provided therein with...
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7622077 |
In situ heat induced antigen recovery and staining apparatus and method
An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of...
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7618587 |
Analyzers and methods of analyzing blood
Analyzers and methods of analysis are described for performing blood cell counting and immunoassay on a whole blood specimen in one measurement section. An assay sample is prepared by blending...
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7611670 |
Quantitative analysis of a biological sample of unknown quantity
Disclosed is a method for testing a modified specimen such as a dried blood spot, plasma or serum specimen, for an analyte of interest, such as cholesterol. In accordance with the disclosed subject...
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7608457 |
Blood collection and testing improvements
Improvements in blood collection and testing. In one aspect, an improved method of manufacturing a blood collection tube, particularly illustrated for use in sedimentation rate testing, including...
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7604999 |
System and method for universal identification of biological samples
A system and method for identifying a biological sample associated with a container is disclosed. A universally unique identifier is associated with each container. In one or more embodiments, the...
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7601546 |
Diagnostic test devices
A diagnostic test apparatus comprising: a shaft having a first end and a second end; a swab or a biopsy punch mounted on the first end of a shaft; and a cap for fitting over the first end of the...
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7598087 |
Protein imprinted polymers with integrated emission sites
This invention provides protein or polypeptide imprinted polymers with integrated emission sites (PIPIES) for detecting the presence of a protein or polypeptide analyte comprising templated sites...
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7597852 |
Substrate for sample analyses
Apparatus and methods for screening a library of materials. Materials are provided in a plurality of locations on a substrate. The locations include first regions that are sufficiently transparent...
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7592181 |
Occult blood testing device
A self-contained system for testing for the presence of occult blood in a specimen has been provided. The system includes a housing holding a test element and a container for releasing a developing...
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7582487 |
Method and device for laminar flow on a sensing surface
Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more...
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7578973 |
Devices for continuous sampling of airborne particles using a regenerative surface
Airborne particles are impacted on a collection surface, analyzed, and then the collection surface is regenerated. Thus, the same collection surface can be used in numerous cycles. The analysis can...
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7575934 |
Oriented magnetic particle-fluorescence detectable moiety compositions and methods of making and using the same
Compositions and methods relating to magnetic particles comprising one or more fluorescence detectable moieties positioned asymmetrically with respect to the magnetic pole regions of the particles...
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7575939 |
Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also...
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7575721 |
Method and apparatus for storing and dispensing reagent beads
Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In one embodiment, an apparatus is provided for dispensing reagent beads...
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7569185 |
Method for indicating shelf-life after mixing pre-dosed, pre-packaged two-part dental compositions
A pre-dosed, pre-packaged mixing system and associated method for mixing, storing, and dispensing a two-part dental composition that becomes less stable upon mixing. The mixing system includes a...
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7563624 |
Measurement method using biosensor
It is an object of the present invention to provide a method for carrying out on a same biosensor both of the measurement of the amount of a physiologically active substance immobilized on a...
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7560272 |
Specimen collection and assay container
The present invention includes but is not limited to a specimen collection device that includes a chamber capable of collecting a specimen, a specimen passage slot, a reservoir, a reservoir seal,...
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7556769 |
Fecal occult test packaging
A specimen testing device having a folding top having a top inside and a top outside; a back portion having at least one flap opening, the back portion in folding communication with the folding...
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7556968 |
Scanning probe microscope and molecular structure change observation method
A scanning probe microscope includes a cantilever, a scanning mechanism which relatively scans the cantilever and a sample which exist in liquid, and an application mechanism which applies...
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7553453 |
Assay implementation in a microfluidic format
An assay implementation in a microfluidic format in a cartridge relating to a point-of-care instrument platform for monitoring and diagnosing infectious diseases (e.g., AIDS and malaria). The...
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7553450 |
Irreversible humidity exposure dose indicator device
An irreversible humidity exposure dose indicator device, including a housing sealed at a first end thereof and adapted at a second end thereof to admit ambient gas ingress into an interior volume...
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7550112 |
Sample collection cup with integrated activatable sample analysis system
Medical and environmental diagnostic devices are described and claimed. Preferred embodiments feature cup within cup configurations wherein one cup is dedicated, for the most part, to sample...
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7547554 |
Method and device for the detection of very small quantities of particles
The invention relates to a method and a device for detecting very small quantities of particles. The inventive method is based on a detection of antigen-antibody reaction products and provides a...
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7544324 |
Rapid sample analysis storage devices and methods of use
The present invention provides test devices for detecting an analyte suspected of being present in a liquid sample. The devices contain a reservoir compartment, a test compartment, and a port for a...
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7544518 |
Rapid quantitative analysis of proteins or protein function in complex mixtures
Analytical reagents and mass spectrometry-based methods using these reagents for the rapid, and quantitative analysis of proteins or protein function in mixtures of proteins. The methods employ...
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7537907 |
Products and methods for single parameter and multiparameter phenotyping of cells
A method of single parameter and multiparameter characterizing of cells, particularly immunophenotyping of cells, is provided. The method preferably uses antibody coated microspheres which are...
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7534578 |
Self-referencing biodetection method and patterned bioassays
The invention relates to compositions and methods for detecting biomolecular interactions. The detection can occur without the use of labels and can be done in a high-throughput manner. The...
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7524456 |
Diagnostic devices for the controlled movement of reagents without membranes
The assay devices, assay systems and device components of this invention comprise at least two opposing surfaces disposed a capillary distance apart, at least one of which is capable of...
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7517694 |
Metering tip with internal features to control fluid meniscus and oscillation
A metering tip for use in a clinical analytical apparatus includes a tapered body having at least one interior stepped areas. Each of the stepped areas include a sharp diametrical edge for latching...
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7507377 |
Device for automatic analysis of a liquid sample
This invention relates to a device usable in an automatical apparatus for the determination of the rate of change of the physical state of a medium. This device has a series of cuvettes having two...
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7507548 |
Multidimensional detection of aberrant phenotypes in neoplastic cells to be used to monitor minimal disease levels using flow cytometry measurements
A method for detecting aberrant phenotypes expressed by neoplastic cells includes the steps of: 1) staining one or more normal/reactive samples and one neoplastic sample with multiple combinations...
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7504264 |
Method for characterizing a highly parallelized liquid handling technique using microplates and test kit for carrying out the method
A method for characterizing highly parallelized liquid handling technology using microplates and test kit for carrying out the method. Possibilities for characterizing a multi-channel or...
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7504072 |
Biopolymeric array scanning devices that focus on the far side of an array and methods for using the same
Array scanning methods that focus on the far side and devices configured for use in the same are provided. In reading arrays according to the subject methods, an array is placed in a reading...
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7494770 |
Mesoscale polynucleotide amplification analysis
Disclosed are devices for amplifying a preselected polynucleotide in a sample by conducting a polynucleotide polymerization reaction. The devices comprise a substrate microfabricated to define a...
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7494818 |
Method for determining concentration of multiple analytes in a single fluid sample
A multilayer test strip that measures concentrations of multiple analytes from a single whole blood sample. The test strip includes a test matrix of several layers held together in constant contact...
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7491542 |
Test device for determining the concentration of LDL-cholesterol in a sample
The present invention provides a test device for determining the concentration of LDL-cholesterol in a sample. The test device has a continuous solid surface with at least one reaction area on the...
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7485472 |
Simple method for quantitative measuring the adhesion of platelets ex vivo
The invention relates to measuring of the adhesion of platelets ex vivo. In this method, monodisperse polymer particles are added to blood, and the number of platelets in the blood are measured...
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7485262 |
Apparatus for chemiluminescent assays
Disclosed herein is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by...
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7483144 |
Apparatus and method for resonant chemical and biological sensing
Apparatus and method are provided for chemical and biological agent sensing. The sensing apparatus includes a resonator having a resonance frequency. The resonator includes a coil of a photonic...
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7473397 |
Device for chemical or biochemical analysis
A device for analysis of a sample, the device comprising: a first layer having a network of passages and chambers through which fluid is caused to flow during analysis; a second layer in which a...
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7470541 |
Automated biological reaction apparatus
An automated immunostaining apparatus having a reagent application zone and a reagent supply zone. The apparatus has a carousel slide support supporting a plurality of slide supports thereon, and...
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7470540 |
Method and device for the integrated synthesis and analysis of analytes on a support
A method for preparing receptor-coated particles is described which comprises the following steps:
a) providing a support body, b) conducting a liquid containing particles into or onto the support...
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7470549 |
Measurement method using biosensor
It is an object of the present invention to provide a method for simultaneously carrying out the detection or measurement of a substance interacting with a physiologically active substance...
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7445938 |
System and method for detecting presence of analytes using gratings
The present invention is directed to an optical grating sensor configured to detect a phase change in light passing though the system due to a binding event caused by an analyte. The grating sensor...
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7439079 |
Assay devices having detection capabilities within the hook effect region
A lateral flow assay device for detecting the presence or quantity of an analyte within a test sample is provided. The device utilizes multiple zones, one of which serves as an indicator of whether...
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