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7615376 |
Masking background fluorescence and luminescence in the optical analysis of biomedical assays
In a process for the quantitative optical analysis of fluorescently labelled biological cells 5 , a cell layer on a transparent support at the bottom 2 of a reaction vessel 1 is in contact...
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7611900 |
High throughput screening methods for lubricating oil compositions
Method for determining deposit formation tendencies for a plurality of fluid samples of different compositions is provided. Each sample includes one or more lubricating oil compositions containing...
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7608463 |
Enhanced waveguide and method
An optical assay apparatus having an optical filter, an optical sensor with a light ray redirection portion and an assay sensing portion, and a filter to block certain wavelengths of excitation...
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7608457 |
Blood collection and testing improvements
Improvements in blood collection and testing. In one aspect, an improved method of manufacturing a blood collection tube, particularly illustrated for use in sedimentation rate testing, including...
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7605004 |
Test strip for a lateral flow assay for a sample containing whole cells
A test strip for conducting a lateral flow assay for detection of an analyte in a sample that contains cells and fluid is provided, as well as methods for making and using the test strip. This test...
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7604999 |
System and method for universal identification of biological samples
A system and method for identifying a biological sample associated with a container is disclosed. A universally unique identifier is associated with each container. In one or more embodiments, the...
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7604984 |
Spatially scanned optical reader system and method for using same
An optical reader system is described herein that uses a scanned optical beam to interrogate a biosensor to determine if a biomolecular binding event occurred on a surface of the biosensor. In one...
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7601544 |
Method and apparatus for using infrared readings to detect misidentification of a diagnostic test strip in a reflectance spectrometer
A method and apparatus for using an infrared reading to detect the misidentification of a diagnostic test strip disposed on a feed table comprising the steps of determining if the test strip...
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7601539 |
Standard material for particle analyzer
A standard material that is used for judging an abnormal portion in a particle analyzer is described. The standard material comprises first standard particles to be fluorescence-stained by a...
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7598088 |
Optical imaging method and system for characterization and mapping of tissue lesions
The present invention provides a method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, caused in the biochemical...
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7598087 |
Protein imprinted polymers with integrated emission sites
This invention provides protein or polypeptide imprinted polymers with integrated emission sites (PIPIES) for detecting the presence of a protein or polypeptide analyte comprising templated sites...
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7597852 |
Substrate for sample analyses
Apparatus and methods for screening a library of materials. Materials are provided in a plurality of locations on a substrate. The locations include first regions that are sufficiently transparent...
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7592181 |
Occult blood testing device
A self-contained system for testing for the presence of occult blood in a specimen has been provided. The system includes a housing holding a test element and a container for releasing a developing...
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7592179 |
Five-part differential white blood cell control and method for preparation of the same
The present invention provides a method for preparing a five-part differential white blood cell control and a white blood cell control prepared thereby. The white blood cell control obtained by the...
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7583379 |
Surface enhanced raman spectroscopy (SERS) systems and methods of use thereof
Surface-enhanced Raman spectroscopic (SERS) systems and methods for detecting biomolecules of interest, such as a virus, bacterium, or other infectious agent, are provided. A spectroscopic assay...
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7582486 |
Double resonance interrogation of grating-coupled waveguides
A method for using a double resonance effect within a grating-coupled waveguide (GCW) sensor, as generated from a light beam with a given span of wavelengths or angles, is provided. The method can...
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7579194 |
Apparatus and method for investigating chemical entities
An apparatus and method for monitoring a large number of binding interactions and obtaining data related to the interactions. In accordance with the illustrative embodiment, the apparatus includes...
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7579192 |
High throughput screening methods for lubricating oil compositions
A method for determining storage stability for a plurality of fluid lubricant samples of different compositions is provided. Each sample includes one or more lubricating oil additives, or a...
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7575939 |
Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also...
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7572642 |
Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns
The invention provides a particle comprising a surface, wherein a portion of the surface is capable of emitting electromagnetic radiation and another portion of the surface is capable of emitting a...
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7572640 |
Method for highly sensitive detection of single protein molecules labeled with fluorescent moieties
Disclosed are methods, kits, and compositions for the highly sensitive detection of molecules. The methods, kits, and compositions are useful in determining concentrations of molecules in samples...
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7569395 |
Method and apparatus for measuring oxygen concentration
An apparatus and non-invasive method of measuring oxygen by exciting a luminescent compound disposed in a container and then measuring the intensity of the light emitted by the excited luminescent...
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7569390 |
Selection of intracellular immunoglobulins
A general immunoglobulin-target assay system is provided, in which a positive outcome (the generation of a signal) depends only on the intracellular interaction of immunoglobulin with target. This...
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7569187 |
Device for removing consumable analytic products from a storage container
A method and a device for removing an analytic consumable product, in particular a test element, from a storage container having chambers which are sealed by foils from which the consumable product...
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7569185 |
Method for indicating shelf-life after mixing pre-dosed, pre-packaged two-part dental compositions
A pre-dosed, pre-packaged mixing system and associated method for mixing, storing, and dispensing a two-part dental composition that becomes less stable upon mixing. The mixing system includes a...
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7563624 |
Measurement method using biosensor
It is an object of the present invention to provide a method for carrying out on a same biosensor both of the measurement of the amount of a physiologically active substance immobilized on a...
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7563623 |
Biosensor
It is an object of the present invention to provide a biosensor on which a large amount of protein can be immobilized and nonspecific adsorption is less likely to occur with the use of a SAM...
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7563587 |
Method and kit for cell analyte assay
The present invention relates to a method for analysing a cell sample for cell surface-bound or intracellularly bound analytes by providing an array of immobilised specific binding agents for a set...
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7560285 |
Micelle-controlled nanoparticle synthesis for SERS
The methods and apparatus disclosed herein concern nanoparticle layers uniformly distributed on a surface or substrate. In certain embodiments of the invention, the nanoparticle layers are of use...
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7560284 |
Fine particles containing rare earth element and fluorescent probe using the same
Fine particles whose excitation light is not UV light or the like which has negative effects on a subject to be analyzed. The excitation light is emitted stably, and has excellent light emitting...
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7556968 |
Scanning probe microscope and molecular structure change observation method
A scanning probe microscope includes a cantilever, a scanning mechanism which relatively scans the cantilever and a sample which exist in liquid, and an application mechanism which applies...
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7556769 |
Fecal occult test packaging
A specimen testing device having a folding top having a top inside and a top outside; a back portion having at least one flap opening, the back portion in folding communication with the folding...
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7553676 |
Specific coupling reaction measuring method
A specific coupling reaction measuring method of this invention for measuring a content of a subject substance in a sample includes the steps of (a) constructing a reaction system including the...
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7553453 |
Assay implementation in a microfluidic format
An assay implementation in a microfluidic format in a cartridge relating to a point-of-care instrument platform for monitoring and diagnosing infectious diseases (e.g., AIDS and malaria). The...
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7550720 |
Apparatus and method for MALDI source control with external image capture
A method of MALDI sample plate processing includes capturing an image of a plate positioned outside a mass spectrometer. The image is processed to identify one or more attributes of an individual...
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7550267 |
Microscale diffusion immunoassay utilizing multivalent reactants
An improved microscale diffusion immunoassay utilizing multivalent reactants is disclosed. In particular, a method for detecting the presence of analyte particles in an analyte fluid is disclosed,...
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7547556 |
Methods for filing a sample array by droplet dragging
A method and an array filling system for loading a plurality of disparate sample containers, the sample containers comprising an integral structure. Each receptacle is characterized by a...
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7547554 |
Method and device for the detection of very small quantities of particles
The invention relates to a method and a device for detecting very small quantities of particles. The inventive method is based on a detection of antigen-antibody reaction products and provides a...
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7547552 |
Indication composition for surgical instrument cleaning evaluation
The present invention provides an indicator composition for evaluating cleaning of a medical instrument that includes an extracellular matrix component and hemoglobin, as a contamination model...
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7547441 |
PAI-2 conjugates for the treatment and imaging of cancer
A method is described for detecting, visualizing, or treating cells, particularly cancerous cells, that express a uPA/uPAR complex. The method employs a PAI-2 conjugate molecule that comprises...
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7544517 |
Stabilized reagent, apparatus and method for measuring cyanuric acid
Reagents for determining presence or concentration of cyanuric acid are described. The reagents include an indicator, a 2,4-diamino-6-alkyl-1,3,5-triazine, caffeine, which acts as a stabilizer, and...
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7544513 |
Hemoglobin assay for neonatal screening
The present invention provides an assay, suitable for neonatal screening of hemoglobinopathies by quantitatively determining the presence of at least one pair of hemoglobin (Hb) variants,...
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7541196 |
Planar optical waveguide based sandwich assay sensors and processes for the detection of biological targets including early detection of cancers
An assay element is described including recognition ligands adapted for binding to carcinoembryonic antigen (CEA) bound to a film on a single mode planar optical waveguide, the film from the group...
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7541193 |
Caged sensors, regulators and compounds and uses thereof
A number of caged (e.g., photoactivatable) compositions are provided, for example, caged enzyme sensors, caged binding sensors, caged nucleic acid probes, caged interfering RNAs, caged antisense...
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7541191 |
Integrated apparatus for hematological analysis and related method
Integrated apparatus and method for hematological analyses, wherein the apparatus comprises, arranged substantially in line and integrated substantially in a single machine, a device ( 14 ) of the...
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7538861 |
Cytological imaging system and method
The present invention relates to the analysis of cytological material. Specifically, the invention relates to stains and methods of producing the stains, methods of staining cells for cytological...
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7537934 |
Chemiluminescence sensor array
Embodiments of the invention relate to integrated chemiluminescence devices and methods for monitoring molecular binding utilizing these devices and methods. These devices and methods can be used,...
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7537907 |
Products and methods for single parameter and multiparameter phenotyping of cells
A method of single parameter and multiparameter characterizing of cells, particularly immunophenotyping of cells, is provided. The method preferably uses antibody coated microspheres which are...
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7534624 |
Method and apparatus for assay in utilizing attenuated total reflection, and sample immobilizing device
A sensor unit for assay in utilizing surface plasmon resonance (SPR) includes a dielectric prism. Metal film has a light entrance surface fitted on the prism, and a sensing surface reverse to the...
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7534615 |
Process for detecting leaks in sealed packages
The present invention relates to a process for detecting a leak in a package. The process comprises preparing a package by covering at least a portion of an O 2 -sensitive product with a multilayer...
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