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7354770 |
Sensing device and method using photo-induced charge movements
A device and method which comprises a sensing surface on a membrane, solid surface or electrode, where the sensing surface contains a dye or chromophore chosen in relation to a particular target...
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7354771 |
Method of determining absolute configuration of chiral compound
The absolute configuration of a chiral compound is determined by (i) coordinating the chiral compound to a metalloporphyrin having a carbon chain-crosslinked porphyrin dimer structure in which one...
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7354727 |
Method and apparatus for classifying B-lymphocytes
A B-lymphocyte classifying method includes the steps of (1) preparing a measurement sample by mixing a blood sample with a lysing reagent to lyse erythrocytes and to shrink the B-lymphocytes in the...
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7354767 |
Reference control composition containing a nucleated red blood cell component made of non-nucleated blood cells
A reference control composition containing a nucleated red blood cell component and the method of making are disclosed. The reference control composition includes a nucleated red blood cell...
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7354772 |
Tag free bio sensing micro strip
A system and method for determining information about an assay. In one embodiment the method includes positioning a filter assembly, having an assay disposed on its surface, relative to a light...
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7351374 |
Surface plasmon enhanced illumination apparatus having non-periodic resonance configurations
An apparatus configured to generate surface plasmon enhanced radiation comprises a metal film having first and second surfaces, and one or more resonance configurations formed in the metal film. An...
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7351588 |
Optical sensor with layered plasmon structure for enhanced detection of chemical groups by SERS
An optical sensor and method for use with a visible-light laser excitation beam and a Raman spectroscopy detector, for detecting the presence chemical groups in an analyte applied to the sensor are...
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7348181 |
Self-encoding sensor with microspheres
A microsphere-based analytic chemistry system is disclosed in which self-encoding microspheres having distinct characteristic optical response signatures to specific target analytes may be mixed...
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7347972 |
Multiple analyte assay device
A test device and associated method of use composed of a housing ( 100 ) defined by base ( 101 ) and cover ( 110 ). The base ( 101 ) has a closed end ( 104 ) and an open end ( 106 ). Slots ( 102 a,...
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7344849 |
Assay
The present invention relates to assay methods for the determination of cobalamin or vitamin B 12 in a body fluid and in particular to assay methods for the metabolically active pool of cobalamin,...
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7344890 |
Method for discriminating platelets from red blood cells
A method for discriminating and quantifying platelets within an analyzed blood sample involves initially diluting the blood sample with a ghosting reagent that causes a change in the index of...
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7335478 |
Reactivation-based molecular interaction sensors
This invention provides methods and systems for linking the functional activation of a responder molecule to the interaction of two or more binding ensemble members of interest either in vitro or...
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7332295 |
Multidimensional leukocyte differential analysis
This invention relates to an improved procedure for the multiparameter analysis of leukocyte subpopulations from peripheral blood, bone marrow or any body fluid containing blood nucleated cells,...
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7332274 |
Process of quality examining for microarray of biological material
The present invention relates a process of quality examining for microarray of biological material. More particularly, the present invention is directed to a process of quality examining for...
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7332128 |
Fiber-optic dissolution systems devices, and methods
A dissolution system provides remote flow cells integrated into a manifold device. The manifold device communicates with liquid input and output lines associated with each flow cell, as well as...
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7332329 |
Versatile substrate for SPR detection
A substrate for testing a carrier liquid for biomolecules using SPR or other techniques provides a metallic island surrounded by a hydrophobic layer, the islands being a location for the attachment...
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7329547 |
FT-NIR fatty acid determination method
A method for the rapid analysis of the fatty acid components present in a fat and/or oil-containing material is provided wherein the levels and types of fatty acids present in a sample are...
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7326577 |
Cell fixation and use in phospho-proteome screening
A new method of cell fixation using a mild denaturing heat and the fixative PERMIFLOW™ or similar fixative that preserves cell morphology, light scatter profiles, nucleic acid content, cell...
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7326576 |
Raman spectroscopic monitoring of hemodialysis
Spectroscopic systems and methods are disclosed for determining levels of at least one analyte in blood undergoing hemodialysis. In one aspect, the invention employs Raman spectroscopy to monitor...
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7323347 |
Biosensor surface structures and methods
A biosensor surface with a low density of ligand-carrying tether molecules on a base layer. Also, surface plasmon resonance (SPR) devices have the biosensor surface attached to a thin gold layer...
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7320775 |
Exchangeable flow cell assembly with a suspended capillary
There is provided a flow cell assembly in which a shuttle supports and positions a capillary with its end extending beyond the shuttle. The flow cell assembly facilitates the replacement of a flow...
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7319040 |
Process control using on-line instrumentation and process models
A method for providing improved estimates of properties of a chemical manufacturing process is disclosed. The method employs a process model that includes, or is modified by, scores or other gains...
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7318907 |
Surface plasmon enhanced illumination system
Methods and apparatus for producing small, bright nanometric light sources from apertures that are smaller than the wavelength of the emitted light. Light is directed at a surface layer of metal...
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7319038 |
Sensor for monitoring an analyte
A food spoilage sensor of the general formula
wherein M is a transition metal ion; D 1 , D 2 , D 3 and D 4 can be the same or different and can be N or P; R 1 and R 2 , R 3 and R 4 , R 5 ...
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7314749 |
Method and apparatus for assay based on light diffraction
The present invention relates to a method and apparatus for detecting analytes in a medium, and more particularly the present invention relates to an assay based on light diffraction which appears...
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7314596 |
Apparatus for sensing coagulation of blood sample
A blood sample sensing apparatus includes a moving device which moves a sample container containing a blood sample to a sensing position, a turning mechanism which is connected to the moving device...
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7312083 |
Control value assignment method
A method of assigning expected recovery values to control substances used in analytical testing is disclosed.
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7312088 |
Method and apparatus for performing SERS analysis using a chemical reference
Apparatus for use in effecting surface-enhanced Raman spectroscopy comprises first and second containment means, the first containment means containing a known quantity of a reference chemical...
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7312069 |
Method of analyzing ligand in sample and apparatus for analyzing ligand in sample
A sample analyzing method capable of high-precision analysis without being affected by vibration and optical design is provided. In the sample analyzing method, a sample containing a ligand is...
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7312090 |
Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
Methods are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also relates to optical...
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7309607 |
Method and device for monitoring platelet function
The invention provides a method of monitoring platelet function in a mammal by passing blood removed from the body of the mammal through a passageway to contact an obstruction or irregularity in...
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7309611 |
Prewetting stop flow test strip
A test strip and method for detecting an analyte present in a sample. The test strip comprising: a buffer addition zone to which a buffer may be added; an absorbent zone proximal to the buffer...
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7306951 |
Method and apparatus for determining diffusible hydrogen concentrations
A measuring apparatus and method for use in measuring diffusible hydrogen concentrations in materials, structures, and other objects. In an embodiment of the invention for use in welding...
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7303726 |
Minimal procedure analyte test system
A system employing an integrated analyte test strip including a biosensor and lancet is disclosed. The integration of lancet and the sensor elements eliminates the need to align the sensor to the...
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7303922 |
Reagentless analysis of biological samples by applying mathematical algorithms to smoothed spectra
Apparatus and method for determining at least one parameter, e. g., concentration, of at least one analyte, e. g., urea, of a biological sample, e. g., urine. A biological sample particularly...
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7303884 |
Method for indirectly determining the blood-clotting status
The invention relates to a method for indirectly determining the blood-clotting status. The inventive method comprises the following steps: a) collecting body fluids which contain a protein that...
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7300799 |
Method to assess organoclay exfoliation and orientation in organoclay/polymer composites
A method for determining degree of organoclay delamination and degree of layer alignment in a polymer organoclay nanocomposite comprising one or more infrared light spectral measurements selected...
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7300804 |
Method and apparatus for controlling the uniform smearing of a biological liquid over a substrate
A method and apparatus for controlling the processing of a liquid sample, e.g., a blood sample, based on a measurement related to the sample's ability to coat a surface against which the sample is...
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7291462 |
TADG-15: an extracellular serine protease overexpressed in carcinomas
The present invention provides DNA encoding a TADG-15 protein as well as a TADG-15 protein. Also provided is a vector capable of expressing the DNA of the present invention adapted for expression...
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7291474 |
Hydrolytic substrates for an analyte-dependent enzyme activation system
Disclosed are compounds of the general formulas:
wherein Y is a moiety capable of being cleaved by a hydrolytic enzyme; L is a detectable label; X is a linking group; Z is a halogen; and R is...
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7288404 |
Microcantilevers for biological and chemical assays and methods of making and using thereof
Disclosed herein are microcantilevers having structural shapes that are less sensitive to turbulence and drift effects yet provide greater deflections due to analyte concentration. The structural...
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7285246 |
Hand-held fluid analyzer
A hand-held device detects the presence of a preselected substance in the breath. A deformable housing forms a test chamber for interacting an indicator reagent with the breath. An ampoule...
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7285418 |
Method and kit for the diagnosis of troponin I
The invention provides a method for assaying for troponin I in a sample such as serum, the method comprising a determination of the troponin I concentration in a sample using a standard preparation...
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7285420 |
System and method for self-referencing a sensor in a micron-sized deep flow chamber
A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a...
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7282367 |
Method for verifying amount of sample solution, method for controlling measurement system and method for measuring concentration of solution in apparatus for measuring optical characteristic
A verification method of a sample solution amount includes the steps of: detecting at least one of a transmitted light component, a scattered light component and a reflected light component of a...
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7282083 |
Methods, systems, and uses for calixarenes
A method of identifying, detecting and/or chemically using NO X compounds is provided, wherein calixarene complexes are exposed to a nitrogen-oxide gas containing samples and form...
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7282373 |
Ultra-high specificity fluorescent labeling
A self-assembled relay probe for detecting a target material is provided including: a first peptide tag bound to the target material; and a first fluorescent conjugate including a first...
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7282331 |
Method for improved specificity in probe based assays
Disclosed are compositions and methods for analyzing a target sequence in a sample. Generally, the method includes use of at least one pair of probes (Probe A and Probe B). In one embodiment, Probe...
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7282370 |
System and apparatus for sequential processing of analytes
An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte...
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7279132 |
Chemical vapor sensor having an active and a passive measurement mode
A chemical vapor sensor is provided that measures a chemical species of interest with high sensitivity and chemical specificity. In an aspect, an ethanol vapor sensor is provided, sized for being...
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