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6103478 |
CDT assay
The invention provides a method of assessment of carbohydrate-deficient transferrin in a transferrin containing body fluid, said method comprising the steps of: i) obtaining a transferrin...
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6096555 |
Process for characterizing the glycosylation of glyco-proteins and for the in vitro determination of the bio-availability of glyco-proteins
The present invention involves a process for characterizing the glycosylation of glyco-proteins and an in vitro process for determining the bioavailability of glyco-proteins, based on the...
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6093327 |
Apparatuses and methods for electrochemically modifying the retention of species on chromatography material
An apparatus and method for electrochemically modifying the retention of a species on a chromatography material is disclosed. The apparatus comprises a housing having an effluent flow channel...
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6087180 |
Method for study and analysis of products of catalytic reaction
Apparatus and process for real time analysis of the intermediates and products of a gas phase chemical reaction catalyzed by a particulate catalyst. Real time analysis is conducted under high...
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6077438 |
Automated on-line evaporation light scattering detection to quantify isolated fluid sample compounds in microtiter plate format
Single pass methods and systems for measuring the total masses of individual compounds present in fluid samples in real time, and particularly for fluid samples prepared in microtiter plate format...
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6074880 |
Sample analyte containing solution fraction collection system, and method of use
Disclosed is a system and method which allows user controlled formation, and ejection of droplets of sample analyte containing solutions, thereby enabling precise user directed fractionalization...
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6063283 |
Method for analyzing a sample by using a liquid chromatograph
A liquid chromatograph includes pumps for supplying solvents, a mixer for mixing the solvents, a controller for controlling a mixing ratio of the solvents in the mixer, a chromatograph column for...
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6063636 |
Method for detecting and diagnosing disease caused by pathological protein aggregation
A method is provided for detecting pathological macromolecules in a patient, comprising obtaining body fluid from the patient, pretreating the body fluid, subjecting the pretreated body fluid to...
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6060325 |
Detection and monitoring of toxic halogenated compounds
The present invention is directed to a method for determining the halogen toxicity level in a sample containing halogenated compounds, specifically halogen containing rubbers by utilizing thermal...
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6058764 |
Analytical apparatus, liquid chromatography analyzer and a method therefor
A reliable analytical apparatus is provided which can produce a highly reliable analytical Value on the basis of data entered during manual sample preparation which can be easily traced and used in...
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6057161 |
Method for determination of drugs of abuse in biological samples
A high purity styrene-divinyl benzene resin is used for rapid solid phase extraction of drugs of abuse from body fluid samples. Simple extraction procedures are described which provide high...
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6051189 |
System and method for detection, identification and monitoring of submicron-sized particles
A system and method for detection, identification, and monitoring of submicron sized particles, the method including the steps of collecting a sample, extracting existing submicron particles from...
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6040186 |
Vial autosampler with selectable modules
A modular vial autosampler has a storage area for vials containing samples to be analyzed and at least one modular sampling station. A vial transfer mechanism lifts a sample vial from the storage...
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6036921 |
Acid or base generator with chromatograph
An apparatus for generating high purity acid or base in an aqueous stream for use as an eluent for chromatography and, particularly, ion chromatography. For generating a base for anion...
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6031228 |
Device for continuous isotope ratio monitoring following fluorine based chemical reactions
An apparatus and method for measuring the isotope ratio of samples containing carbon and nitrogen compounds. The method includes steps of (a) adding a sample containing carbon or nitrogen compounds...
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6030844 |
Method and apparatus for pre-analyzing treatment for subsequent analysis of metal components in volatile alkali solution and non-volatile anion in volatine acid solution and method and apparatus for the subsequent analysis
Method of pre-treating a sample for metal analysis, the sample including a volatile alkali, by permeating the volatile alkali through a gas permeable membrane, dissolving the volatile alkali in an...
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6025202 |
Self-assembled metal colloid monolayers and detection methods therewith
A biosensor based on complexes between biomolecule receptors and colloidal Au nanoparticles, and more specifically, colloid layers of receptor/Au complexes that can be used to detect biomolecule...
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6020203 |
Chromatographic method for determination of glycated proteinaceous species in blood
A method for continuous separation and analysis of glycated and non-glycated proteins in a blood sample by HPLC using a phenylboronic acid resin and a polyol as eluant.
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6020205 |
Determination of intracellular antioxidant levels
A method of determining intracellular levels of water-soluble and fat-soluble antioxidants. Peripheral blood mononuclear cell lysates are prepared from an individual and analyzed by HPLC, either...
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6013462 |
Glutathione analogs as reagents
Compounds of the formula ##STR1## or the alkyl (1-6C), alkenyl (1-6C), or arylalkyl (7-12C) amides or salts including the cycloamido forms thereof; wherein n is 1 or 2; wherein when n is 1, X...
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6008054 |
Method of measuring a β-glucan
For the purpose of improving the accuracy and reproducibility of the measurement of β-glucan by flow injection method using calcofluor, the present invention provides a method in which a gel...
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5998589 |
Method of purifying human factor VIII
The invention is a method of purifying Factor VIII comprising the steps of contacting a solution containing Factor VIII with a Factor VIII-binding substrate under conditions sufficient to bind...
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5998217 |
Method of introducing standards into a vial
A modular vial autosampler has a storage area for vials containing samples to be analyzed and at least one modular sampling station. A vial transfer mechanism lifts a sample vial from the storage...
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5993662 |
Method of purifying and identifying a large multiplicity of chemical reaction products simultaneously
The invention provides a system utilizing computer databases, high pressure liquid chromatography and mass spectrometry to isolate, purify and identify compounds present in a chemical library of...
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5985581 |
Use of presenilin-1 for diagnosis of alzheimers disease
The invention provides a method of diagnosing Alzheimer's disease. The method utilizes presenilin-1, whose level is found to be substantially decreased in Alzheimer's patients. Included in the...
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5981283 |
Method of tagging hydrocarbon fuels
A liquid hydrocarbon fuel composition comprises at least one tagging agent and a mixture of hydrocarbon components having boiling points in the range of about 100 degrees F. to about 800 degrees F....
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5962334 |
Process for extracting 2,3,7,8-tetrachlorodibenzo-p-dioxin
A process for the extraction and purification of TCDD (2,3,7,8-Tetrachlorodibenzo-p-dioxin) from a sample matrix. The process of the present invention overcomes a problem of prior art processes for...
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5962774 |
Real-time monitoring of volatile organic compounds using chemical ionization mass spectrometry
A system for on-line quantitative monitoring of volatile organic compounds (VOCs) includes pressure reduction means for carrying a gaseous sample from a first location to a measuring input location...
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5958785 |
Detection of a carbohydrate biomarker directly associated with chronic alcoholism
Chronic or long-term alcohol consumption is detected and diagnosed by determining the levels of an alcohol-specific ethanol glycoconjugate biomarker, identified as ethyl β-glucuronide, in body...
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5952556 |
Gas chromatograph with carrier gas control system
A gas chromatograph includes a carrier gas supply flow path to which a pressure sensor, resistance tube, and control valve are sequentially connected. A differential pressure sensor is situated on...
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5952235 |
Detection of teratogen exposure
The present invention relates to methods for detecting teratogen exposure in neonates. In particular, the present invention is directed to the detection of prenatal (i.e., in utero) exposure to...
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5948360 |
Autosampler with robot arm
A modular vial autosampler has a storage area for vials containing samples to be analyzed and at least one modular sampling station. A vial transfer mechanism includes an arm having a gripper that...
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5945342 |
Method for digesting spent ion exchange resins and recovering actinides therefrom using microwave radiation
The present invention relates to methods for digesting diphosphonic acid substituted cation exchange resins that have become loaded with actinides, rare earth metals, or heavy metals, in a way that...
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5942400 |
Assays for detecting β-secretase
Compositions comprising a novel protease capable of cleaving β-amyloid precursor protein (APP) on the amino-terminal side of the β-amyloid peptide therein are provided. The protease is designated...
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5939612 |
Retention time-locked spectral database for target analyte analysis
Screening an unknown sample for a plurality of known or "target" analytes may be accomplished by creating and searching a retention time-locked spectral database for the entire chromatographic...
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5938931 |
Method for processing liquid chromatographic data
A data processing method in a liquid chromatograph provided with a column, a device for pouring an eluting solution into the column to elute respective samples injected into the column to thereby...
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5938932 |
High-throughput method and apparatus for identifying, quantitating and determining the purity of chemical compounds in mixtures
A method and apparatus for high-throughput identity confirmation, quantitation and purity determination of a compound of interest in a mixture of compounds is disclosed. According to the method, a...
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5935522 |
On-line DNA analysis system with rapid thermal cycling
An apparatus particularly suited for subjecting biological samples to any necessary sample preparation tasks, subjecting the sample to rapid thermal cycling, and then subjecting the sample to...
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5932481 |
Method for measuring metaplastic changes of mucus secreting epithelial cells
A method for the rapid estimation of hyperplastic and hypertrophic changes in animal airways is an assay which specifically measures acidic and neutral mucoproteins in a linear fashion from 0.5 to...
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5928956 |
Method of examining silane-treated, inorganic materials
The invention relates to a method of examining inorganic materials which are treated with organosilicon compounds, wherein the sample material is pyrolyzed within a few seconds and the pyrolysis...
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5919708 |
Assay for glycated blood proteins
A method of assessing glycated blood protein in a sample which comprises separating glycated and non-glycated protein using a liquid phase precipitation reagent, contacting the sample with a signal...
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5915269 |
Method and apparatus to compensate for gas chromatograph column permeability
In a gas chromatograph system having a column with a stationary phase and a carrier gas moving through the column to contact the stationary phase, the system being useful for detecting analytes in...
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5908556 |
Automatic ionic cleanliness tester
An automatic ion residue monitoring and testing system that has a particular application to quantify ionic residue on a printed circuit board. The monitoring system is a stand-alone unit that...
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5885838 |
Method of identifying chemicals by use of non-radioactive isotopes
A method is disclosed for identifying the source of a transported chemical shipment. The method employs either a chemical element or an organic compound with one or more atoms that are...
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5885786 |
Methods for screening of substances for inhibition of multidrug resistance
The present invention provides for the screening of candidate substances to identify active compounds that inhibit multidrug resistance (MDR). The expression of glucosylceramides has been...
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5872010 |
Microscale fluid handling system
A microscale fluid handling system that permits the efficient transfer of nanoliter to picoliter quantities of a fluid sample from the spatially concentrated environment of a microfabricated chip...
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5866429 |
Precision and accuracy of anion-exchange separation of nucleic acids
Solvents for salt-gradient anion-exchange separation of nucleic acids, especially double-stranded DNA and especially by liquid chromatography, are improved by replacing NaCl as the eluting salt...
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5861317 |
Automatic sample injector and method of operating same
An automatic sample injector for injecting a liquid sample into a vaporization chamber of a gas chromatograph includes a syringe, a plunger adapted to move inside the barrel of this syringe, a...
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5856196 |
Processes for quantitating phosphoglycerides in a lipid mixture and diagnostic uses therefor
Processes for detecting or quantitating a particular phosphoglyceride in a sample containing the phosphoglyceride and other lipids and clinical uses for the process (e.g. for diagnosing improperly...
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5854080 |
Process for separating tritiated water
A process and apparatus for separating tritium from an aqueous solution that contains one or more additional dissolved radionuclides is disclosed. In accordance with the process the aqueous...
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