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6468804 |
Suppressor for continuous electrochemically suppressed ion chromatography and method
Methods and devices for continuous electrochemically suppressed ion chromatography are disclosed. In preferred aspect of the invention, a chloromatography effluent comprising analyte ions and...
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6461515 |
Parallel liquid chromatography for analyzing combinatorial libraries of non-biological polymers
A method is disclosed for characterizing non-biological polymers using liquid chromatography that is particularly useful in polymer research programs. The method includes the steps of providing a...
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6460401 |
Method and apparatus for trace analysis of organic compound
The invention relates to a method of trace analysis of organic compounds which calls for the steps of setting a test piece in a flow cell, and thereafter removing organic compounds from the test...
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6454947 |
Overlaid injection for rapid characterizations of polymers
A method is disclosed for characterizing a plurality of non-biological polymer samples. The method includes the steps of injecting a first non-biological polymer sample into a mobile-phase of a...
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6444475 |
Ion chromatography apparatus and method for removing gas prior to sample detection
Methods and devices for removing gas prior to detecting analyte ions are discolored. In one aspect of the invention, gas by-products from the suppression of the mobile phase are removed prior to...
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6440745 |
Combinatorial synthesis and screening of organometallic compounds and catalysts
The present invention relates, inter alia, to methodologies for the synthesis, screening and characterization of organometallic compounds and catalysts (e.g., homogeneous catalysts). The methods of...
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6428702 |
Method of sample introduction for supercritical fluid chromatography systems
An improved method and apparatus for safely introducing sample into a flow stream of a supercritical fluid chromatography system is described. The sample injection method improves safety of...
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6428703 |
Method for purifying biological marcromolecules, and chromatographic column for performing said method
The invention concerns a method for purifying biological macromolecules, e.g. nucleic acids or proteins, from starting materials, in which the macromolecules, contained in a biological solution,...
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6428704 |
Method for determination of hemoglobins
A method for determining hemoglobins is provided which is suitable for determination of stable hemoglobin A 1c . A method for determining hemoglobins by cation exchange liquid chromatography...
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6425284 |
Method and apparatus for gas-assisted suppressed chromatography
Ionic species in an aqueous sample stream are analyzed by (a) chromatographically separating the ionic species in the presence of an aqueous eluent solution comprising electrolyte to form a...
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6426006 |
Automated on-line evaporating light scattering detection to quantify isolated fluid sample compounds in microtiter plate format
Single pass methods and systems for measuring the total masses of individual compounds present in fluid samples in real time, and particularly for fluid samples prepared in microtiter plate format...
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6416663 |
Chromatographic column for rapid characterizations of polymers
Rapid characterization and screening of polymer samples to determine average molecular weight, molecular weight distribution and other properties is disclosed. Rapid flow characterization systems...
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6413431 |
HPLC method for purifying organic compounds
An HPLC method which purifies and/or characterizes large numbers of related compounds, for example, those prepared for use in combinatorial libraries, is disclosed. The compounds are purified on a...
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6406632 |
Rapid characterization of polymers
Rapid characterization and screening of polymer samples to determine average molecular weight, molecular weight distribution and other properties is disclosed. Rapid flow characterization systems...
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6387273 |
Sample preparation for high throughput purification
An HPLC method for purifying and/or characterizing large numbers of related compounds, for example, combinatorial and lead generation libraries, is disclosed. The compounds are purified on a...
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6380538 |
Ion source for a mass analyser and method of cleaning an ion source
An ion source for a low pressure mass spectrometer has an atmospheric pressure sample ioniser operative at relatively higher pressure to provide a sample flow containing desired sample ions to the...
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6372510 |
Method for removing unconventional transmissible agents from a protein solution
The present invention is drawn to method for removing unconventional transmissible agents (UCTA) from aqueous protein solution. This method involves treating the aqueous protein solution with...
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6368865 |
Combinatorial process for performing catalytic chemical reactions
A combinatorial process for simultaneously conducting multiple catalytic chemical reactions in parallel has been developed. At least one catalyst is contained in the reaction zones of a plurality...
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6342160 |
Method for screening chromatographic adsorbents
The invention discloses a method for rapid identification of a candidate selective separation material by placing small samples of the candidate material in an array of vials and adding a solution...
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6335202 |
Method and apparatus for on-line measurement of the permeation characteristics of a permeant through dense nonporous membrane
This invention relates to a method and apparatus for on-line measurement of permeation characteristics (transmitting chemicals) through dense nonporous membrane. This invention is intended to...
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6333198 |
Compound and its use
A method of testing the purity or stability to degradation of a sample of lamotrigine or a pharmaceutical dosage form comprising lamotrigine comprises assaying the said sample for the presence of a...
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6331400 |
Method for characterization of the fine structure of protein binding sites
The binding sites of binding proteins and their binding partners are characterized, at the individual amino acid level, by a combination of tritium exchange labeling and sequential degradation and...
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6316185 |
Quantitation of viruses by light scattering
A method for determining the number or concentration of virus particles in a sample by use of a light scattering detector. The method may be used to quantitate purified virus preparations or virus...
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6316270 |
Acid base or generator
A method for generating high purity acid or base in an aqueous stream for use as an eluent for chromatography and, particularly, ion chromatography. For generating a base for anion chromatography,...
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6296771 |
Parallel high-performance liquid chromatography with serial injection
High-performance liquid chromatography (HPLC) methods and systems are disclosed that combine sequential, serial injection of a plurality of samples into mobile-phases supplied in parallel to two or...
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6291247 |
Methods of screening for factors that disrupt neurotrophin conformation and reduce neurotrophin biological activity
Factors and methods for disrupting or inhibiting the association of protomers of a multimeric protein are described. Such inhibition reduces the biological disorders. Particularly, novel...
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6287521 |
Methods and devices for obtaining and assaying mammary fluid samples for evaluating breast diseases, including cancer
Non-invasive methods are provided for obtaining biological samples of mammary fluid or mammary fluid components by administering oxytocin to a patient to stimulate expression of mammary fluid....
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6281019 |
Device for non-pulsating post-column derivatization
A device for performing a post-column derivatization in connection with liquid chromatography includes a separating column, a detector, an eluent withdrawal unit, connected to an outlet of the...
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6275775 |
Method for determining at least one physico-chemical property of a petroleum fraction
A method for determining at least one physico-chemical property of a petroleum fraction is described in which a conventional analysis of the property is done for a reference petroleum sample set;...
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6271038 |
Methods for high throughout determination and ranking of formulations and solubility
The invention provides apparatus and methods for formulation mixing and measurement to produce rank orders of solubility of chemicals in a variety of formulations. One such method includes mixing a...
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6237396 |
Integrated analysis process and device for hydrocarbon characterization by distillation simulation
Integrated analysis process and device for characterization of hydrocarbons in a petroleum product, in distillation fractions, by simulated distillation. The hydrocarbons of a petroleum sample are...
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6235197 |
Electrochemically regenerated ion neutralization and concentration devices and systems
A system and method for electrochemically regenerated ion neutralization and concentration is disclosed. In one aspect of the invention, a system is provided comprising a HPLC column pump, a...
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6235489 |
Method for diagnosing and distinguishing stroke and diagnostic devices for use therein
A method for determining whether a subject has had a stroke and, if so, the type of stroke which includes analyzing the subject's body fluid for at least four selected markers of stroke, namely,...
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6225047 |
Use of retentate chromatography to generate difference maps
This is invention is directed to methods of identifying analytes that are differentially present between two samples. The methods involve determining retention data by desorption spectrometry for...
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6225132 |
Enhanced chromatography using multiphoton detection
A method for detecting an analyte of interest present in a mixture at an ultralow concentration includes selecting a radioactive derivatizing agent comprising a multiphoton-emitting radioisotope...
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6225129 |
Large capacity acid or base generation apparatus and method of use
Method and apparatus for generating an acid or base, e.g. for chromatographic analysis of anions. For generating a base the method includes the steps of providing a cation source in a cation source...
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6210970 |
Method of diagnosing or categorizing disorders from biochemical profiles
A method for diagnosing disorders in a subject organism, in which fluid samples from normal and abnormal organisms are analyzed to generate electrical signal patterns representative of molecular...
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6208941 |
Method and apparatus for analysis of chromatographic migration patterns
The present invention includes a method and apparatus for the detection and analysis of information-containing signals in chromatographic data using iterative blind deconvolution and fuzzy logic...
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6187595 |
Method for detecting polymers in a solution, detector system and chromatography apparatus containing such a detector system
A method of quantitatively detecting a polymer in a solution of the polymer in a solvent is provided, which method comprises the steps of (a) adding to the solution a non-solvent for said polymer...
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6180413 |
Low level TOC measurement method
A method for the determination of total organic carbon in an aqueous sample by trapping the organic matter on a sorbent which is carbon free and analyzing the sorbent by combustion and...
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6180417 |
Immunochromatographic assay
Disclosed is a device and method for carrying out an assay for an analyte in a fluid test sample by immunochromatography. The device involves a strip having a non-porous receiving member of a...
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6174732 |
Analytical methodology for qualitative and quantitative determination of chemical agent vapor
A method for producing and sampling chemical agent vapor comprising the steps of placing neat chemical agent in a reservoir, purging the chemical agent in the reservoir with a dry air, and...
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6162398 |
Assay device using shrink wrap
Devices for conducting an assay are disclosed which utilize shrink wrap as a casing material. The use of shrink wrap casings enables the preliminary fluid filtering step and the chemical detection...
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6156577 |
Method of measuring amount of polyphenol compound
A method of measuring an amount of a polyphenol compound in a liquid sample containing at least one polyphenol compound comprises a step of separating the liquid sample into each component, a step...
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6153438 |
Retention factor database
A method for identifying analytes of interest by referencing to a retention factor database corresponding to a plurality of identified analytes that is independent of column dimensions and carrier...
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6153101 |
Device for ion-exchange chromatography and method of cyclically regenerating a plurality of suppressors of such a device
In order to regenerate a plurality of suppressors (6, 6a, 6b) that are inserted alternatingly into a device for ion-exchange chromatography, apart from an analysis branch (9), at least one...
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6149882 |
Parallel fixed bed reactor and fluid contacting apparatus
The present invention discloses an apparatus and method for rapid analysis of members of a combinatorial library. The apparatus includes a plurality of vessels for containing individual library...
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6146895 |
Method of static headspace analyzer
A method of preparing a volatile sample from a material for gas chromatographic analysis includes the steps of: introducing a vial with the material containing the volatile sample and a headspace...
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6130095 |
Method for the measurement of sulfur compounds
An improved system for the measurement of sulfur compounds is described. The system comprises an enclosed burner assembly for the conversion of sulfur-containing compounds to sulfur monoxide and...
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6125689 |
Non-destructive semiconductor wafer test system
The invention provides methods and systems for identifying compounds released from a semi-conductor wafer. Compounds are released from the wafer by subjecting the wafer to a rapid temperature...
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