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8183046 |
Temperature resistant pH buffers for use at low temperatures
A method for preparing a composition that includes selecting a pH of the composition; selecting a first buffer with a negative temperature coefficient; selecting a second buffer with a positive...
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8158430 |
Systems and methods of fluidic sample processing
The present invention provides fluidic devices and systems that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care...
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8114633 |
Methods for differentiating plasma-derived protein from recombinant protein in a sample
The present invention relates, in general, to methods for detecting and quantitating plasma-derived protein and recombinant protein in a sample based on the difference in protein glycosylation,...
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8088624 |
Method of detecting thrombosis by measuring von Willenbrand factor-cleaving protease
A method of detecting thrombosis or the degree of thrombophilia by measuring a von Willebrand factor cleaving protease, and a kit for detecting thrombosis or the degree of thrombophilia, comprising...
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8084223 |
Detection of false results in assays
Methods and reagents are disclosed for detecting a false result in an assay for determining a concentration of an analyte in a whole blood sample suspected of containing the analyte. The method...
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8071384 |
Control and calibration solutions and methods for their use
Control and calibration solutions are described that provide control and calibration data that is recognized by a test meter allowing the meter to segregate the control and calibration data from...
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8066958 |
Device and kit for calibrating bodily fluid sampling devices
A control solution packet for calibrating a bodily fluid sampling device includes a container, a control solution pressurized within the container, and a membrane for covering and sealing the...
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7888053 |
Making encoded ghost cells for multiplexed detection of anti-red cell alloantibodies
Disclosed are methods for detecting antibody in a sample, where the antibody targets an antigen expressed by red blood cells or red blood cell ghosts. Rather than detecting the binding events...
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7842463 |
Method of diagnosing early stage renal impairment
There is disclosed a method of diagnosing early stage renal impairment in humans, characterized by the following steps: measuring the amount of apoA-IV in a body liquid or tissue sample of a human,...
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7803046 |
Simulcast pari-mutuel gaming machine with casino and lottery styled wagers for continuous play
An gaming machine for and method of par-mutuel wagering that allows individuals to continuously place multiple casino and lottery styled pari-mutuel wagers on simulcast live and/or recorded...
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7776601 |
Method for determining and monitoring ageing of blood bags
The invention concerns a method which consists in determining ageing an ageing index of a blood bag (11, 62), to determine whether the blood bag is or not suitable for transfusion to a patient. The...
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7754436 |
Diagnostic assay for stroke
Heart and brain fatty acid binding proteins (H-FABP, B-FABP) are markers for stroke. The invention provides a diagnostic assay for either of these markers, preferably by ELISA using a anti-H-FABP...
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7732210 |
Multi-analyte reference solutions
The present invention provides a reference solution for use in instruments that determine hematocrit levels in biological samples by measuring the resistance and/or conductivity of the biological...
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7727769 |
Measurement result correction method, urine analysis system, and urine analyzer
A urine analysis system includes a urinary particle analyzer and a computer. The urinary particle analyzer has a measuring unit that measures a cast concentration from the urine and an electric...
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7722858 |
Prevention and treatment of atherosclerosis by reducing carbamylation of LDL or the effects of carbamylated LDL
The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of measuring the level of cLDL and/or autoantibody to cLDL in a...
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7718387 |
Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays
The present invention relates to the field of immunology and hyperproliferative diseases. More specifically, the present invention relates to a method of detecting and monitoring therapeutic...
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7695973 |
Determination of glycated protein
The present invention provides methods for quantitation of glycated protein in a biological sample using a solid support matrix by making a first bound protein measurement total bound protein under...
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7670846 |
Automatic differentiation of a sample solution and a control solution
The invention concerns a method for automatically differentiating between a sample liquid and a control liquid especially within the context of analytical measuring systems, wherein the presence of...
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7659122 |
Single population of simulated leukocyte granules, calibrators comprising the same and methods of preparing the same
Disclosed is a single population of simulated leukocyte granules prepared from mammalian whole white blood cells, which is useful in calibrators for a hematology analyzer, a calibrator which...
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7618792 |
Multiplexed detection of anti-red cell alloantibodies
Disclosed are methods for detecting antibody in a sample, where the antibody targets an antigen expressed by red blood cells or red blood cell ghosts. Rather than detecting the binding events...
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7601539 |
Standard material for particle analyzer
A standard material that is used for judging an abnormal portion in a particle analyzer is described. The standard material comprises first standard particles to be fluorescence-stained by a...
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7598089 |
Methods and compositions for separating cells
The invention provides compositions and methods for cell separation. These reagents and techniques specifically agglutinate cells via surface antigen recognition and can be used to recover rare...
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7592179 |
Five-part differential white blood cell control and method for preparation of the same
The present invention provides a method for preparing a five-part differential white blood cell control and a white blood cell control prepared thereby. The white blood cell control obtained by the...
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7580119 |
Method and apparatus for chemical monitoring
The present invention relates to monitoring chemicals in a process chamber using a spectrometer having a plasma generator, based on patterns over time of chemical consumption. The relevant patterns...
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7534616 |
Uninterrupted flow pump apparatus and method
This invention describes a method for pumping or delivering fluids utilizing a flexible vessel subject to controlled pressures within another pressure vessel. The pressure vessel can be sourced...
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7494782 |
Assay for measuring factor viia-antithrombin complexes
A method for determining the concentration of factor VIIa-antithrombin complexes is disclosed which has application to estimating the level of intravascular exposure of tissue factor, assessing...
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7476551 |
Diagnosing atherosclerosis risk by measuring carbamylated low density lipoprotein levels
The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of: measuring the level of carbamylated LDL in a sample obtained...
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7462489 |
Methods for identifying and analyzing biomarkers from plasma-derived microparticles
The present invention provides methods for identifying candidate biomarkers in the plasma microparticle proteome. It also provides methods for isolating, identifying, and analyzing microparticles...
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7422903 |
Multi-analyte reference solutions
The present invention provides a reference solution for use in instruments that determine hematocrit levels in biological samples by measuring the resistance and/or conductivity of the biological...
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7422848 |
Hepatitis-B viral variants with reduced susceptibility to nucleoside analogs and uses thereof
The present invention relates generally to the field of Hepatitis B variants exhibiting a reduced sensitivity to nucleoside analogues, both in vivo and in vitro. More in particular, reverse...
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7393688 |
Method of using a hematology reference control for measurement of immature granulocytes
A method of using a reference control for measurement of immature granulocytes on a blood analyzer is disclosed. The method includes analyzing a reference control that contains an immature...
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7390663 |
Process, composition and kit for providing a stable whole blood calibrator/control
The present invention is directed toward a stable calibrator and/or control, kit and process for using in a glucose monitoring instrumentation. Principally, the instant invention teaches a...
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7390677 |
Immunoassay and immunoassay apparatus
An immunoassay comprises the steps of: (a) mixing a whole blood sample with sensitized insoluble carrier particles smaller than erythrocytes to cause an immune agglutination reaction; (b)...
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7368247 |
Diagnostic assay for transmissible spongiform encephalopathies
Heart and brain fatty acid binding proteins (H-FABP, B-FABP) are markers for TSEs, especially CJD. The invention provides a diagnostic assay for either of these markers, preferably by enzyme...
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7285418 |
Method and kit for the diagnosis of troponin I
The invention provides a method for assaying for troponin I in a sample such as serum, the method comprising a determination of the troponin I concentration in a sample using a standard preparation...
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7195923 |
Ratiometric determination of glycated protein
The present invention provides methods for determining a ratio of an amount of a glycated form of a protein to a total amount of the protein in a sample containing the glycated protein, the...
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7172902 |
Quality control material for reagentless measurement of analytes
A method of monitoring calibration of a spectrophotometric apparatus that includes one or more than one calibration algorithm for one or more than one analyte, involves measuring absorbance of a...
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7156662 |
Light gun for pistol and rifle
A light gun includes a trigger unit; a grip coupled to the trigger apparatus; and a barrel unit coupled with the trigger apparatus. The trigger unit has a trigger and a hammer, and the barrel unit...
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7151000 |
Method of concentrating proteins from serum
A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected...
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7148067 |
Thromboplastin reagents
A thromboplastin reagent includes tissue factor, Factor VIIa, and a net negatively charged phospholipid. The thromboplastin reagent is a synthetic thromboplastin reagent, and is in dried form.
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7144705 |
Diagnostic assay for stroke
Heart and brain fatty acid binding proteins (H-FABP, B-FABP) are markers for stroke. The invention provides a diagnostic assay for either of these markers, preferably by ELISA using anti-H-FABP or...
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7109036 |
Hematology reference control containing an immature granulocyte component
A hematology reference control containing an immature granulocyte component and the method of making are disclosed. The reference control includes an immature granulocyte component made of...
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7026131 |
Methods and apparatus for blood typing with optical bio-discs
This invention relates to clinical diagnostic assays, related optical bio-discs, and a disc-reading apparatus. The invention is directed to methods and apparatuses for performing immunohematology...
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7011940 |
Quality control for cytochemical assays
The invention describes quality control devices for assays that measure analytes in cells and tissue samples, and methods of use thereof. In particular, the quality control device comprises a...
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6984526 |
Spectrophotometric method for determining the viability of a sample containing platelets
A method and apparatus for characterizing the type of a blood sample and a variety of blood components are provided wherein a transmission spectrum of the sample is collected over a predetermined...
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6929952 |
Gaming device having a bonus scheme with symbol generator and symbol terminating condition
A gaming device with a bonus scheme which includes a symbol generator and a plurality of symbols. When two or more predetermined symbols are generated and displayed, the bonus round terminates....
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6900058 |
Control solution for photometric analysis
An aqueous control solution is disclosed for use with a spectrophotometer or photometric test strip that includes a predetermined amount of an analyte, a hydrophobic reference dye and a surfactant....
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6852540 |
Control serum for dry analytical element
A control serum for a dry process is provided that does not show misfit in measurement values by the dry process and a wet process. The above-mentioned control serum is obtained by freezing or...
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6852541 |
Rapid assay for testing overall oxidative stress
The invention relates to an assay for testing oxidative stress of a subject by measurement of oxidants in biological fluids such as urine, plasma, bioreactor medium and respiratory aspirants. There...
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6835571 |
Multi-analyte reference solutions with stable pO2 in zero headspace containers
Multi-analyte reference solutions having a stable partial pressure of oxygen (pO2) in zero headspace packaging and methods for preparing such solutions are disclosed. The solutions have long shelf...
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