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7615376 |
Masking background fluorescence and luminescence in the optical analysis of biomedical assays
In a process for the quantitative optical analysis of fluorescently labelled biological cells 5 , a cell layer on a transparent support at the bottom 2 of a reaction vessel 1 is in contact...
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7585682 |
Magnetic in situ dilution
The invention involves methods, assays, and components for the detection and analysis of binding between biological or chemical species, and can specifically be used for drug discovery. In an...
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7575933 |
Modification of selectivity for sensing for nanostructure device arrays
An electronic system for selectively detecting and identifying a plurality of chemical species, which comprises an array of nanostructure sensing devices, is disclosed. Within the array, there are...
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7531136 |
Chemical sensor
The application relates to a chemical sensor device comprising a substrate ( 1 ), a sensor medium ( 3 ) formed on the substrate, the sensor medium comprising one-dimensional nanoparticles, wherein...
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7504262 |
High sensitivity biomolecule detection with magnetic particles
The present invention generally relates to the field of biomolecule detection. More specifically, the present invention relates to compositions, methods and systems for the detection and...
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7501091 |
Sensors with improved properties
A sensor or a sensor array connected to an electrical measuring apparatus is disclosed. In one embodiment, at least one sensor contains a layer of conductive modified particles which forms an...
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7495300 |
Gas-sensing semiconductor devices
A gas-sensing semiconductor device is fabricated on a silicon substrate having a thin silicon oxide insulating layer in which a resistive heater made of a CMOS compatible high temperature metal is...
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7494816 |
System and method for determining a temperature during analyte measurement
A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC...
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7488991 |
Molecular controlled semiconductor device
A semiconductor sensing device for sensing presence, absence or level of species-of-interest in the environment is disclosed. The semiconductor sensing device comprises at least one layer of...
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7488601 |
System and method for determining an abused sensor during analyte measurement
A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC...
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7459312 |
Photodesorption in carbon nanotubes
Carbon nanotube devices are manipulated in a manner that is useful for a variety of implementations. According to an example embodiment of the present invention, light ( 632 ) is used to...
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7455979 |
Polysaccharide structure and sequence determination
The invention provides a method for the structural analysis of a saccharide, comprising: a) providing on a surface a plurality of essentially sequence- and/or site-specific binding agents; b)...
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7442555 |
Ammonia gas sensor method and device
A mixed potential sensor device and methods for measuring total ammonia (NH 3 ) concentration in a gas is provided. The gas is first partitioned into two streams directed into two sensing chambers....
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7416699 |
Carbon nanotube devices
Nanotubes and nanotube-based devices are implemented in a variety of applications. According to an example embodiment of the present invention, a nanotube is adapted to pass current between two...
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7407811 |
System and method for analyte measurement using AC excitation
A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC...
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7404928 |
Thiol terminated monodisperse ethylene oxide oligomer capped gold nanoclusters
A thiol terminated ethylene oxide oligomer and the method of substituting the oligomer onto a gold nanocluster surface using a thiol-exchange reaction to form a charge-neutral, non-ionizable, water...
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7396683 |
Detection of allergen-associated materials
Measurement of the redox properties of household dust is used to detect the presence of allergen-associated materials. Measurement may be electrochemical, preferably amperometric. A disposable...
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7391225 |
Carbon nanotube sensor and apparatus and method for detecting change time of engine oil for automobile using the same
A system and method for determining the time to change the oil of an automobile engine including a power source unit for converting power into necessary power and supplies power at the startup...
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7374942 |
Process and apparatus for the combinatorial production and testing of catalyst material libraries by using at least two analytical methods
A process and apparatus for testing material libraries, in particular catalysts, by means of coupled use of at least two analytical methods, preferably IR thermography and mass spectrometry. Owing...
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7354770 |
Sensing device and method using photo-induced charge movements
A device and method which comprises a sensing surface on a membrane, solid surface or electrode, where the sensing surface contains a dye or chromophore chosen in relation to a particular target...
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7347974 |
Materials, method and apparatus for detection and monitoring of chemical species
A method for investigating a target environment to determine whether or in what amount a chemical species may be present therein, which comprises: (a) exposing to said environment an article of...
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7341694 |
Ammonia sensor
In an ammonia sensor ( 1 ), lead portions ( 7 ) and ( 9 ) are provided on an insulating substrate ( 5 ); a pair of comb-shaped electrodes ( 11 ) and ( 13 ) are connected to the lead portions ( 7 )...
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7338811 |
Integrated circuit chip for bioassays
The invention is directed to novel IC chips containing substances used particularly in bioassays. Furthermore, the invention is directed to assay methods and kits using these chips.
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7338639 |
System and method for analyte measurement
A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC...
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7329389 |
Sensor device and method for qualitative and quantitative analysis of gas phase substances
New sensors and methods for qualitative and quantitative analysis of multiple gaseous substances simultaneously with both high selectivity and high sensitivity are provided. The new sensors rely on...
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7314761 |
Leak sensor for flowing electrolyte batteries
A leak detection system for a flowing electrolyte battery comprising a containment member associated with at least one of a stack of a flowing electrolyte battery and an electrolyte reservoir of a...
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7291503 |
Reversible resistivity-based sensors
One aspect of the present invention relates to a method for detecting the presence of an analyte by comparing the conductivity of a mixture containing an analyte and a sensor to the conductivity of...
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7291310 |
Microsystem for determining clotting time of blood and low-cost, single-use device for use therein
A microsystem for determining clotting time of blood and a low-cost, single-use device for use therein are provided wherein the device has no moving parts or expensive optical sensors or magnets....
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7267751 |
Programmable multiplexed active biologic array
The present invention is directed to devices and methods for carrying out and/or monitoring biological reactions in response to electrical stimuli. A programmable multiplexed active biologic array...
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7247494 |
Scanner with array anti-degradation features
A reader is provided that, itself, addresses the issue of damage or degradation to arrays within the reader by virtue of air exposure. In doing so, experimental variability is reduced, and...
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7247485 |
Karl Fischer reagent
Karl Fischer reagent comprising iodide, sulphur dioxide with an initial concentration above 0.5 M, and imidazole/imidazole derivative dissolved in alcoholic solvent, whereby the molar ratio between...
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7247271 |
Compact ceramic sensor for fuel volatility and oxygenate concentration
A compact ceramic fuel property sensor comprises a plurality of laminated ceramic layers. The heater, temperature sensor, and capacitance measurement electrodes are embedded between the layers. The...
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7226563 |
Ion-detecting sensors comprising plasticizer-free copolymers
Plasticizer-free ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers...
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7223607 |
Process and device for the detection of hydrocarbons in a gas
The invention relates to a process for the detection of hydrocarbons other than methane in a gas predominantly or essentially comprising oxygen, as well as methane and the said hydrocarbons other...
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7211439 |
Selective chemical sensors based on interlinked nanoparticle assemblies
The invention relates to a nanoparticle film comprising a nanoparticle network formed of nanoparticles interlinked by linker molecules. The linker molecules have at least two linker units that can...
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7208322 |
Sensor surfaces for detecting analytes
The present invention provides a sensor surface comprising: a substrate coated with a free electron metal; and a matrix layer disposed on the free electron metal, wherein the matrix layer comprises...
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7205153 |
Analytical reagent for acid copper sulfate solutions
Embodiments of the invention provide an analytical method and analytical reagent solutions for determining the concentration of electrolyte components, such as copper, acid and chloride...
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7201876 |
Ion-detecting sensors comprising plasticizer-free copolymers
Ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers having pendent...
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7195923 |
Ratiometric determination of glycated protein
The present invention provides methods for determining a ratio of an amount of a glycated form of a protein to a total amount of the protein in a sample containing the glycated protein, the...
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7189503 |
Characterization of individual polymer molecules based on monomer-interface interactions
The invention relates to a method for detecting a double-stranded region in a nucleic acid by (1) providing two separate, adjacent pools of a medium and a interface between the two pools, the...
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7189315 |
Ion sensor and clinical analyzer using the same
An ion sensor has a flow path through which a sample flows. An ion-exchange membrane is in contact with the sample in the sample flow path. An internal solution is provided on one side of the...
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7183117 |
Apparatus for measuring characteristics of chemical solution, chemical solution supply apparatus, and method for measuring concentration of chemical solution
A supply apparatus for preparing a mixed chemical solution of a predetermined mixing ratio at a low cost and for supplying the mixed chemical solution stably. The supply apparatus includes a...
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7179659 |
Sensor surfaces for detecting analytes and methods of use
The present invention provides a method for detecting an analyte, comprising providing a sensor comprising a substrate coated with a free electron metal, a matrix layer disposed on the free...
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7179605 |
Fibronectin precursor biopolymer markers indicative of alzheimer's disease
The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers...
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7169618 |
Magnetic particles and methods of producing coated magnetic particles
An improved method for separating materials is provided, using colloidal, magnetizable aggregates, optionally silanized, and coated with a one or more layers of novel polysaccharide derivatives....
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7153693 |
Method and apparatus for determining urea concentration
A method for determining a urea concentration in an aqueous solution containing urea, includes: hydrolyzing the urea in the aqueous solution, measuring an electric conductivity χ of the aqueous...
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7150997 |
Multiplexed active biologic array
A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method,...
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7138280 |
Masking of the background fluorescence and luminescence in the optical analysis of biomedical assays
In a process for the quantitative optical analysis of biological cells labelled with a fluorescent dye, the sensitivity of analytical detection can be considerably improved if a masking dye, which...
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7135297 |
Protein biopolymer markers indicative of insulin resistance
The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers...
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7129095 |
Method and system for using a weighted response
The present invention is related to the sensing of analytes and in particular, to methods of determining, resolving, identifying, or quantitating such analytes once detected. This invention...
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