|
Match
|
Document |
Document Title |
|
|
8173382 |
Assay for cardiac troponin autoantibodies
The invention provides among other things methods and kits based on assaying for cardiac troponin autoantibodies, either in conjunction with an assay for cardiac troponin and/or as an independent...
|
|
|
8168402 |
Diagnostic tests of substance use disorders
The present invention relates to compositions and methods for identifying and quantifying platelet proteins that relate to various bodily states. The present invention further provides methods and...
|
|
|
8163559 |
White blood cell differentiation reagent and method
A reagent for four-part differentiation of white blood cells is provided. In one embodiment the reagent has an osmolality below 50 mOsm/kg H2O. A method for differentiating white blood cells using...
|
|
|
8158434 |
Method for performing counts within a biologic fluid sample
A method for enumerating cellular elements and particulates within a biologic fluid sample is provided. According to one aspect of the invention, the method includes the steps of: a) providing a...
|
|
|
8158429 |
Multicolor reagents containing compensation controls
The present invention provides multicolor reagent formulations containing in a single container both fluorescently labeled detection reagents and single-color compensation control reagents, wherein...
|
|
|
8150645 |
Automatic analzyer
Measurement of the uncertainty used for quality control typically involves a plurality of factors. When the uncertainty exceeds a clinical permissible value, time is required for a medical...
|
|
|
8148094 |
Methods and compositions for detecting the activation state of multiple proteins in single cells
The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides...
|
|
|
8143064 |
Reagents and methods for classifying leukocytes
A reagent for classification of leukocytes includes (a) at least two cationic surfactants; (b) at least one organic compound bearing a hydrophobic group and an anionic group; (c) a buffer for...
|
|
|
8137975 |
Method for a rapid antibody-based analysis of platelet populations
A method for identifying a platelet population, preferably a population of immature, reticulated platelets, in a biological sample involves incubating the biological sample for less than 5 minutes...
|
|
|
8137987 |
Simultaneous assay for determining drugs
Bodily fluid is analyzed for the presence of drugs of a selected panel of drugs in a simultaneous assay in which sample of the fluid is incubated with additional amounts of all drugs of the panel,...
|
|
|
8114580 |
Simulation of normal fresh blood platelets for reference control
The present invention provides for novel analogs of fresh human platelets for use in hematological instrument. Methods for preparing such analogs are also described.
|
|
|
8110407 |
Fluorescent semiconductor microparticle assembly, fluorescent labeling agent assembly for biological substance, and bioimaging method and biological substance analysis method using the assemblies
Disclosed is a fluorescent semiconductor microparticle assembly comprising at least three kinds of fluorescent semiconductor microparticles with an average particle size of from 1 to 10 nm, having...
|
|
|
8101414 |
Reagent for sample analysis, reagent kit for sample analysis and method for sample analysis
A reagent for measuring a basophil and/or a nucleated red blood cell is described. The reagent comprises (a) an alcohol having 4 to 8 total carbon atoms, and (b) one or more fluorescent dyes...
|
|
|
8080383 |
Method of discriminating at least two cell populations, and application
A subject of the invention is a method for discriminating between and counting at least two populations of biological elements carrying specific characteristics, optionally present in a sample. The...
|
|
|
8076095 |
Method for enumeration of mammalian micronucleated erythrocyte populations, while distinguishing platelets and/or platelet-associated aggregates
A method for the enumeration of micronucleated erythrocyte populations while distinguishing platelet and platelet-associated aggregates involves the use of a first fluorescent labeled antibody...
|
|
|
8071384 |
Control and calibration solutions and methods for their use
Control and calibration solutions are described that provide control and calibration data that is recognized by a test meter allowing the meter to segregate the control and calibration data from...
|
|
|
8062860 |
Kit for measuring in vivo mutation frequency at an endogenous gene locus
The present invention relates a method for the enumeration of in vivo gene mutation. The method utilizes differential staining of GPI-anchor deficient erythrocyte populations to distinguish between...
|
|
|
8030094 |
Self-encoding sensor with microspheres
A microsphere-based analytic chemistry system is disclosed in which self-encoding microspheres having distinct characteristic optical response signatures to specific target analytes may be mixed...
|
|
|
8029978 |
Processing method for the long-term stabilization of biological red blood cell volume
The present invention relates to a processing method for long-term stabilization of biological red blood cell volume. The red blood cells can be further used in reference materials and calibrators...
|
|
|
8008032 |
Tagged ligands for enrichment of rare analytes from a mixed sample
Method of enriching specific cells from cellular samples are disclosed, comprising contacting in solution a cellular sample with affinity-tagged ligands (ATLs) each comprising a first ligand linked...
|
|
|
8008089 |
Method and system for checking measurement result
A system for checking measurement results is provided with a urine qualitative analyzer for measuring the specific gravity of a urine, urinary particle analyzer for measuring urine conductivity,...
|
|
|
8008029 |
Method and device for characterizing cellular components of a biological fluid
The invention concerns a method for differentiating and counting cellular components present in a biological fluid sample comprising a primary cytological analysis step typically implemented by a...
|
|
|
7981682 |
High resolution flow cytometer
High resolution particle differentiation process and separation system that provides enhanced resolution of particles based upon selected particle characteristics. In particular, the system may...
|
|
|
7981681 |
Method for the analysis of a blood sample, and apparatus and reagent for its implementation
Method for the automatic analysis of a blood sample in which: an analysis solution containing the blood sample, a diluent, and at least one compound to lyze the erythrocytes; at least one compound...
|
|
|
7968279 |
Reference control for cell by cell analysis
A reference control for cell by cell analysis on flow cytometric analyzers contains cellular analogs made of permeated blood cells containing therein aggregated intracellular proteins and preserved...
|
|
|
7947465 |
Simultaneous assay for determining drugs
Bodily fluid is analyzed for the presence of drugs of a selected panel of drugs in a simultaneous assay in which sample of the fluid is incubated with additional amounts of all drugs of the panel,...
|
|
|
7943397 |
Methods and algorithms for cell enumeration in low-cost cytometer
The enumeration of cells in fluids by flow cytometry is widely used across many disciplines such as assessment of leukocyte subsets in different bodily fluids or of bacterial contamination in...
|
|
|
7943383 |
Apparatus and method for automatically determining the validity of white blood sample measurements based on the characteristics of optical scattering data
A blood analyzer configured to prevent an abnormal number of white blood cells caused by lipid particles or red blood cells of poor hemolysis from being output. The blood analyzer includes a system...
|
|
|
7943327 |
Simultaneous assay of target and target-drug binding
Whole cell, simultaneous target and drug-target assay using differentially labeled antibodies and flow cytometry. First antibody binds to total target and second antibody binds to the drug binding...
|
|
|
7939278 |
Methods and compositions for risk stratification
The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of...
|
|
|
7901950 |
Method for assessing disease states by profile analysis of isolated circulating endothelial cells
Elevated number of Circulating Endothelial Cells (CEC) have been implicated in disease conditions associated with the formation or destruction of blood vessels such as acute coronary syndrome,...
|
|
|
7897328 |
Blood group antigens of different types for diagnostic and therapeutic applications
The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection and blood typing.
|
|
|
7892841 |
Method and apparatus for measuring hematological sample
A measuring method and a measuring apparatus which can classify and count myeloblast more precisely without influence of other component in a sample including platelet aggregation in measurement of...
|
|
|
7879569 |
Methods for diagnosis of myelodysplastic syndromes (MDS)
The present invention relates to methods and kits for diagnosing, ascertaining the clinical course a of myelodysplastic syndrome(MDS) and ascertaining response to a therapy regimen of...
|
|
|
7867765 |
Blood cell sorting methods and systems
The invention relates to methods of isolating white blood cells (WBCs) from a sample, e.g., whole blood, using magnetic particles that specifically bind to WBCs and a series of specific steps and...
|
|
|
7863012 |
Analysis of circulating tumor cells, fragments, and debris
The methods and reagents described in this invention are used to analyze circulating tumor cells, clusters, fragments, and debris. Analysis is performed with a number of platforms, including flow...
|
|
|
7855078 |
High resolution flow cytometer
High resolution particle differentiation process and separation system that provides enhanced resolution of particles based upon selected particle characteristics. In particular, the system may...
|
|
|
7850916 |
Disposable chamber for analyzing biologic fluids
An apparatus for analyzing biologic fluid is provided that includes a first planar member, a second planar member, and at least three separators. At least one of planar members is transparent. The...
|
|
|
7842247 |
Sample holder for dynamic light scattering
A sample holder holds various sizes of capillaries or cuvettes for use in dynamic light scattering (DLS) or quasi-elastic light scattering (QELS), such as in DLS of fluid samples such as platelet...
|
|
|
7838296 |
Methods and apparatus for ultrasonic determination of red blood cell indices
The present invention provides an apparatus and method for measuring the properties of blood using ultrasound. The present invention is particularly suitable for measuring HCT, HGB, MCV, RBC, MCHC,...
|
|
|
7824916 |
Sheath liquid for particle analyzer
A sheath liquid for a particle analyzer used to analyze particles contained in a sample is described. The sheath liquid includes water and a refractive-index adjustment agent with glycerols and/or...
|
|
|
7824874 |
Method for measuring in vivo mutation frequency at an endogenous gene locus
The present invention relates a method for the enumeration of in vivo gene mutation. The method utilizes differential staining of GPI-anchor deficient erythrocyte populations to distinguish between...
|
|
|
7807389 |
Methods and compositions related to joint inflammation diseases
Disclosed are compositions and methods related to joint inflammation diseases. Disclosed is the relationship between osteoclasts and inflammatory joint diseases and osteoclast precursor cells.
|
|
|
7803624 |
Automated cytological sample classification
An automated method for classifying a cytological sample is provided. The method comprises interrogating the sample with one or more wavelengths of light to obtain a result, and then attaching one...
|
|
|
7785898 |
Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood
The present invention provides methods for identifying and/or enriching fetal cells from maternal blood, using as fetal cell markers the antibodies that the mother produces against paternally...
|
|
|
7781227 |
Multiplex microparticle system
Arrays of microparticle populations, each population labeled with a single fluorescent dye, are provided for use in multiplex assays. The populations form a virtual multidimensional array wherein...
|
|
|
7776605 |
Assay for cardiac troponin autoantibodies
The invention provides among other things methods and kits based on assaying for cardiac troponin autoantibodies, either in conjunction with an assay for cardiac troponin and/or as an independent...
|
|
|
7776612 |
Method of quantifying antigen expression
The present invention is directed to a novel method for quantifying antigen, such as the amount expressed on a cell. The method comprises formulating an equation of correlation between the amount...
|
|
|
7754498 |
Self-encoding sensor with microspheres
A microsphere-based analytic chemistry system is disclosed in which self-encoding microspheres having distinct characteristic optical response signatures to specific target analytes may be mixed...
|
|
|
7754487 |
Hematology linearity control composition, system and method of use
A linearity control system includes a series of linearity control compositions, each thereof includes white blood cell analogs and stabilized red blood cells in a suspension medium. The...
|