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9034602 Modified beta-lactamases and methods and uses related thereto  
The present invention relates to pharmaceuticals and modified beta-lactamases. Specifically, the invention relates to novel recombinant beta-lactamases and pharmaceutical compositions comprising...
9034609 Bio-engineered multi-enzyme complexes comprising xylanases and uses thereof  
The present invention relates to bio-engineered multi-enzyme complexes having synergistic enzyme activity comprising xylanases and optionally further comprising additional carbohydrate active...
9034636 Microfluidic hanging drop chip  
A microfluidic hanging drop chip is disclosed. Also disclosed are methods for culturing cells and forming cell aggregates in hanging drops.
9034615 Glycolic acid production by fermentation from renewable resources  
The present invention provides a method for the biological production of glycolic acid from a fermentable carbon source in a microorganism. In one aspect of the present invention, a process for...
9035148 Maize inbred PH1MBR  
A novel maize variety designated PH1MBR and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1MBR with another maize plant. Methods...
9034612 Compositions and methods for making and modifying oils  
The invention provides novel methods for making or modifying oils, e.g., plant animal or microbial oils, such as vegetable oils or related compounds, that are low in a particular fatty acid(s),...
9034635 Thermocycler and sample vessel for rapid amplification of DNA  
A thermocycler apparatus and method for rapidly performing the PCR process employs at least two thermoelectric modules which are in substantial spatial opposition with an interior space present...
9034590 Method for detecting substance in biological sample  
The present invention provides a method for detecting a substance in a biological sample, a carrier for using in the method, and a kit. The method of the present invention includes 1) providing a...
9034330 Preparation of antibody or an antibody fragment-targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof  
A method of preparing an antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex comprises the steps of (a) preparing an antibody or antibody fragment; (b) mixing said...
9034581 Compositions and methods for detection of Staphylococcus aureus  
The present invention relates to methods for the rapid detection of the presence or absence of Staphylococcus aureus in a biological or nonbiological sample. The present invention includes methods...
9034575 Workflow timing between modules  
The invention relates to a method of isolating and analyzing an analyte using an analytical apparatus which comprises modules of different types, wherein any one module of one type has a specific,...
9034343 Attenuated human parainfluenza virus, methods and uses thereof  
The invention provides self replicating infectious recombinant paramyxoviruses. The recombinant paramyxovirus preferably have one or more attenuating mutations. In some embodiments, the...
9034610 Polypeptides and biosynthetic pathways for the production of monatin and its precursors  
Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided....
9034624 Process for the synthesis of conjugates of glycosaminoglycanes (GAG) with biologically active molecules, polymeric conjugates and relative uses thereof  
The present invention relates to a process for the synthesis of conjugates of glycosaminoglycanes (GAG) with biologically active molecules of varying nature, comprising small molecules and...
9034577 Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell  
In one aspect, the invention provides methods and compositions for the expression of small RNA molecules within a cell using a retroviral vector (FIG. 1A). Small interfering RNA (siRNA) can be...
9034592 Immunoassay for quantification of an unstable antigen selected from BNP and proBNP  
The present invention relates to an immunoassay for detection of BNP, proBNP and fragments thereof. Essentially the assay comprises: a) contacting the antigen with a first antibody specific to a...
9034648 Artificial tissue construct and method for producing the same  
An object of the present invention is to provide an artificial tissue construct that has means for transporting nutrients, oxygen, waste products, or the like and is viable in vivo. The present...
9034574 Agents for reversing epigenetic silencing of genes  
The present invention provides methods for discovering agents that are effective in reversing epigenetic silencing by inhibiting the interaction of methyl-binding (MBD) proteins with methylated...
9034646 Virally-inactivated growth factors-containing platelet lysate depleted of PDGF and VEGF and preparation method thereof  
The invention concerns human platelet extracts rich in growth factors (PGF) for wound healing and stem cell expansion. Accordingly the subject invention relates to a virally-inactivated growth...
9034622 Preparation for photodynamic control of microorganisms and use thereof  
The invention relates to a preparation for the photodynamic control of micro-organisms, said preparation being in a liquid or pasty form and containing a photosensitizer which comprises a dyestuff...
9034631 Systems and methods for yeast propagation  
The present invention relates to systems and methods for propagating yeast using a feedstock material such as starch and one or more enzymes (e.g., an enzyme cocktail) to break down the feedstock...
9034583 Rapid enzyme-linked immunosorbent assay for detection and identification of pathogens and determination of antimicrobial susceptibility  
The present invention provides a rapid, highly sensitive and specific enzyme-linked immunosorbent assay (ELISA), referred to as N-Assay, a device, and a kit, for detection and identification of...
9034344 Chimeric adenoviruses for use in cancer treatment  
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of...
9035128 Hybrid light chain mice  
Genetically modified mice are provided that express human λ variable (hVλ) sequences, including mice that express hVλ sequences from an endogenous mouse λ light chain locus, mice that express hVλ...
9034633 Method for bioremediation of highly aromatic hydrocarbon wastes  
Disclosed herein is a method for biopile-based bioremediation of hydrocarbon waste with high aromatic content. The method comprises of isolating specific microorganisms and preparing microbial...
9035156 Plants and seeds of corn variety CV052803  
According to the invention, there is provided seed and plants of the corn variety designated CV052803. The invention thus relates to the plants, seeds and tissue cultures of the variety CV052803,...
9035149 Maize inbred PH1K8P  
A novel maize variety designated PH1K8P and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1K8P with another maize plant. Methods...
9034660 Detection of analytes via nanoparticle-labeled substances with electromagnetic read-write heads  
A first set of antibodies are bonded to a substrate, and are exposed to and bonded with target antigens. A second set of antibodies are bonded to nanoparticles, and the nanoparticle labeled...
9034625 High fidelity restriction endonucleases  
Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins....
9035137 Soybean variety XR31L13  
A novel soybean variety, designated XR31L13 is provided. Also provided are the seeds of soybean variety XR31L13, cells from soybean variety XR31L13, plants of soybean XR31L13, and plant parts of...
9034595 Integrated bioprocessing for fuel production  
Systems and methods are provided for enhancing the integration of processes for recovering products from algae-derived biomass. The enhanced process integration allows for increased use of input...
9034313 Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same  
Nucleic acid molecules comprising a nucleotide sequence encoding RANTES and fragments and variants thereof are disclosed. Additionally, nucleic acid molecules and compositions comprising the...
9029082 Detection device for detecting biological microparticles such as bacteria, viruses, spores, pollen or biological toxins, and detection method  
A device for the detection of micro particles that can be marked by probes or antibodies capable of being detected by radiation has a filter, a supply system, and a detection system. Fluid to be...
9029132 Sensor for biomolecules  
A sensor for biomolecules includes a silicon fin comprising undoped silicon; a source region adjacent to the silicon fin, the source region comprising heavily doped silicon; a drain region...
9028664 Proton concentration topographies, methods and devices for producing the same  
A device for isoelectric focusing. The device comprises a focusing container configured to contain an electrolyte solution and having a longitudinal axis and at least one electrolysis unit mounted...
9029342 Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof  
A method for treating and/or diagnosing pain and the source or type of pain, shock, and/or inflammatory conditions in a subject. A method of using a therapeutically effective amount of a DNA or...
9029089 Methods for predicting survival in cancer patients  
A method for survival prediction in cancer patients is provided. In one embodiment, the survival prediction is determined by the presence or absence of KRAS gene region deletion and/or loss of...
9028811 Methods for promoting HSC self-renewal  
The present invention provides for compositions and methods for modulating hematopoetic stem cell populations by using HCS modulators, which are agents that either increase HSC numbers or decrease...
9029111 Isolation and characterization of a novel pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains  
The present invention relates to a polynucleotide encoding an omega 3 (ω-3) desaturase from Pythium irregulare with specificity to long chain polyunsaturated omega 6 (ω-6) fatty acids as well as a...
9028834 Pneumovirus compositions and methods for using the same  
Provided are newly identified pneumoviruses that can infect mammals, including dogs cats and potentially humans. Isolated polynucleotides and proteins of the viruses, as well as the isolated...
9029126 Process and method for improving the water reuse, energy efficiency, fermentation and products of an ethanol fermentation plant  
A method of hydrothermally treating stillage by heating stillage to 200 degrees F. to 350 degrees F., altering physicochemical properties of the stillage, enabling facile separation of the...
9029094 Biomechanical-based methods of diagnosing scoliosis  
Methods for diagnosing a scoliosis (e.g., adolescent idiopathic scoliosis (AIS)) and/or a predisposition to developing a scoliosis based on the determination of the variation of osteopontin (OPN)...
9029092 Solution phase homogeneous assays  
Methods, reagents, kits and systems are disclosed for determining an analyte in a sample suspected of containing the analyte where all reagents are soluble in aqueous solution. One assay method...
9029091 Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line  
The present invention provides a structural characterization platform that can be used to assess the stability of a polyclonal cell line during production, as well as batch-to-batch consistency of...
9028838 Influenza hemagglutinin and neuraminidase variants  
Polypeptides, polynucleotides, methods, compositions, and vaccines comprising (avian pandemic) influenza hemagglutinin and neuraminidase variants are provided.
9029110 Method for producing functional microbially fermented tea extract containing polyphenol derivative  
A functional microbially fermented tea extract containing a novel polyphenol derivative and a method for producing the same are provided. A functional microbially fermented tea extract containing...
9029401 Sorafenib derivatives as sEH inhibitors  
The present invention provides compounds for the inhibition of soluble epoxide hydrolase and associated disease conditions.
9029108 Pulsed electric field (PEF) method for continuous enhanced extraction of oil and lipids from small aquatic plants  
A pulsed electric field method for the continuous extraction of oil and lipids from small aquatic plants, the method including providing a continuous flow of a slurry of small aquatic plants. A...
9029114 Type II restriction-modification system methylation subunit of Alicyclobacillus acidocaldarius  
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering...
9029161 Apparatus and method for dating a body or body sample  
A method and apparatus for dating a body sample, such as blood, includes taking at least one spectroscopic measurement of the sample at at least two predetermined positions in the spectrum having...