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7608436 |
Process for producing saccharide oligomers
A process for preparing saccharide oligomers uses an aqueous feed composition that comprises at least one monosaccharide or linear saccharide oligomer, and has a solids concentration of at least...
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7560126 |
Amylases, nucleic acids encoding them and methods for making and using them
In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and...
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7556945 |
Method for converting sucrose to β-D-glucose
Disclosed is an apparatus and method for continuously converting sucrose to β-D-glucose. The method comprises a three-stage enzymatic reactor in which an aqueous solution of sucrose is first...
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7524654 |
Isomaltulose synthases, polynucleotides encoding them and uses therefor
The invention is directed to novel enzymes that convert sucrose to isomaltulose. More particularly, the present invention discloses novel sucrose isomerases, polynucleotides encoding these sucrose...
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7488390 |
Corn and fiber refining
Plant materials such as corn kernels which contain starch and fiber comprising cellulose, hemicellulose, lignin, and pectin are refined. The starch, cellulose, hemicellulose, and pectin are...
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7452425 |
Corn refining process
A grain containing starch, such as corn, is refined. The grain is steeped in water at a temperature of about 125 to 160° F., which water is essentially free of sulfurous acid and contains recycled...
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7282359 |
Plant 1-deoxy-D-xylulose 5-phosphate reductoisomerase
This invention relates to an isolated nucleic acid fragment encoding a 1-deoxy-D-xylulose 5-phosphate reductoisomerase. The invention also relates to the construction of a chimeric gene encoding...
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7264962 |
Enzymatic cascade bioreactor
Disclosed is an apparatus and method for continuously converting sucrose to β-D-glucose. The method comprises a three stage enzymatic reactor in which an aqueous solution of sucrose is first...
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7238473 |
TTP-related zinc finger domains and methods of use
The present invention provides methods of regulating the destruction of mRNA molecules containing an AU-rich element (ARE), for example, methods of stimulating the degradation of an mRNA molecule...
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7226731 |
PB 39, a gene dysregulated in prostate cancer, and uses thereof
A novel gene, PB39, that is up-regulated, or over-expressed, in prostate cancer has been identified. The gene has been identified by means of its cDNA obtained by reverse transcription of the...
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7176293 |
Compositions and methods to enhance sensitivity of cancer cells to mitotic stress
An isolated nucleic acid sequence of a mitotic checkpoint gene, chfr, encodes a Chfr protein having a Forkhead-associated domain and a Ring Finger. This protein is required for regulation of the...
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7052898 |
Thermostable isomerase and use hereof, in particular for producing tagatose
A novel L-arabinose isomerase active enzyme and its corresponding gene, derived from a thermophilic source are provided. The enzyme is suitable for the production of D-tagatose, a useful...
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7026142 |
Methods for enzymatic conversion of GDP-mannose to GDP-fucose
This invention provides methods for practical enzymatic conversion of GDP-mannose to GDP-fucose. These methods are useful for efficient synthesis of reactants used in the synthesis of fucosylated...
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6991923 |
Process for manufacturing of tagatose
Tagatose is manufactured by hydrolyzing lactose to galactose and glucose and isomerizing galactose to tagatose and chromatographic separation and recycling any unconverted compounds. Thereby high...
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6974671 |
Methods for indentifying compounds that modulate gluconeogenesis through the binding of CREB to the PGC-1 promoter
In accordance with the present invention, it has been discovered that CREB regulates hepatic gluconeogenesis via the co-activator, PGC-1. PGC-1 potentiated glucocorticoid induction of the gene for...
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6946281 |
N-acetylglucosamine 2-epimerase and DNA encoding the same
The present invention provides a novel protein having N-acetylglucosamine 2-epimerase activity; a DNA encoding the protein; a recombinant vector containing the DNA; a transformant obtainable by...
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6933138 |
Thermostable L-arabinose isomerase and process for preparing D-tagatose
Disclosed are a novel gene coding for L-arabinose isomease derived from Thermotoga neapolitana 5068, a thermostable arabinose isomerase expressed from the said gene, a recombinant expression...
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6919176 |
Polypeptides and nucleic acids associated with cancer
The present invention provides methods, reagents, and kits for diagnosing and treating cancer in a mammal, e.g., a human. This invention is based upon the discovery that G2A, GPR4, GPR65, and OGR1...
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6913878 |
Method of detecting DNA single strand breaks
A method of detecting increased levels of DNA single strand breaks in a eukaryotic cell sample, comprising the steps of: (a) contacting a eukaryotic cell sample to a water-soluble tetrazolium salt...
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6911565 |
Process for the production of xylitol
The present invention relates to a process for the production of xylitol. The process utilises ribulose for the preparation of xylitol and involves several different conversion reactions, such as...
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6902903 |
Helicobacter pylori diagnostics
Novel methods, membrane supports and immunodiagnostic test kits for diagnosing Helicobacter pylori infection, are disclosed. The methods can also be used to monitor the progress of treatment of...
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6897047 |
Heat-resistant mannose isomerase, process for producing the same and process for producing mannose by using the same
A thermostable mannose isomerase generated from a bacterium belonging to the genus Agrobacterium , excellent in thermostability, capable of being continuously used at a temperature of 55° C. to...
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6893818 |
Gene upregulated in cancers of the prostate
The present invention relates to a novel protein designated 20P2H8 which shares homology with several heterogenous nuclear ribonucleoproteins (hnRNPs). A full length approximately 3600 bp 20P2H8...
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6846656 |
Process for producing N-acetylneuraminic acid
The present invention provides a process for economically producing N-acetylneuraminic acid without using expensive materials such as pyruvic acid and phosphoenolpyruvic acid. The process...
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6825013 |
Isolation of biosynthesis genes for pseudo-oligosaccharides from Streptomyces glaucescens GLA.O, and their use
The invention relates to a recombinant DNA molecule which comprises genes for biosynthesizing acarbose and homologous pseudo-oligosaccharides; to oligonucleotide primers for the PCR amplification...
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6746847 |
Diagnostic assay for human matrix Gla-protein and its use as a biomarker
A diagnostic assay, preferably immunoassay, is provided for the detection and determination of MGP in a human serum sample, which comprises the use of one or more antibodies, in particular...
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6743602 |
Polynucleotides differentially expressed in adenocarcinomas, polypeptides encoded thereby, and methods of use thereof
The present invention features human HX2004-6 polypeptide and nucleotide sequences encoding HX2004-6 polypeptides. In a particular aspect, the polynucleotide is the nucleotide sequence of SEQ ID...
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6713287 |
Enzymatic synthesis of L-fucose and L-fucose analogs
Fucose and fucose analogs are synthesized enzymatically in a three step synthetic protocol. In the first step, L-fuculose-1-phosphate of analog thereof is produced by means of an aldolase catalyzed...
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6686147 |
Cancer associated antigens and uses therefor
Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in testis cells using antisera from seminoma patients. The invention relates...
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6673581 |
Mannose isomerase and DNA encoding the enzyme
The present invention provides a novel protein having mannose isomerase activity, DNA encoding the protein, a recombinant vector comprising the DNA, a transformant obtained by introducing the...
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6673544 |
Method for the light-controlled synthesis of biochips
The present invention relates to a method for the photolithographic synthesis of biochips in which photolabile protective groups of the 2-(2-nitrophenyl)ethyl type are used, whereby the irradiation...
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6670329 |
Selenocosmia huwena toxin and analgesic uses thereof
Disclosed is a analgesic composition containing the purified HWAP-I polypeptide of the Chinese bird spider, Selenocosmia Huwena.
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6664383 |
Polypeptides, cDNA encoding the same and utilization thereof
A new human polypeptide, a cDNA encoding the same and a pharmaceutical use of it. The polypeptides of the present invention possess hematopoiesis regulating activity, tissue...
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6610486 |
Methods of screening nucleic acids for nucleotide variations
The present invention provides a method of detecting nucleotide variation within a first nucleic acid, comprising generating a set of single-stranded extension products from a first nucleic acid in...
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6599699 |
Methods for diagnosing a disorder by assaying for MAGE-3
The invention relates to nucleic acid molecules which code for the tumor rejection antigen precursor MAGE-3. Also disclosed are vectors, cell lines, and so forth, which utilize the nucleic acid...
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6423490 |
Method for measuring the concentration of polynucleotides
A method for measuring the presence of polynucleotide in a sample, comprising the steps of: (1) preparing a sample, an agglutinative agent and an agglutination promoter capable of binding to...
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6410265 |
Gene encoding a putive efflux protein for solvents/antibiotics in Pseudomonas mendocina
This invention relates to the isolation of a novel putative efflux gene from Pseudomonas mendocina . The putative efflux gene is useful for probing an organism's efflux system to gain an...
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6395518 |
Method and reagents for combined PCR amplification and hybridization probing
An oligonucleotide probe is disclosed, the probe including an oligonucleotide, a fluorescer molecule attached to a first end of the oligonucleotide and a quencher molecule attached to the opposite...
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6379888 |
Universal probes and methods for detection of nucleic acids
Signal primers are employed for detection of nucleic acid target sequences by fluorescence quenching mechanisms. The signal primer comprises a first and a second oligonucleotide and is partially...
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6355420 |
Methods and products for analyzing polymers
Methods and products for analyzing polymers are provided. The methods include methods for determining various other structural properties of the polymers.
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6348326 |
Process for producing L-ribose
L-Ribose is produced by the steps of producing ribitol from a saccharide raw material by using a microorganism having an ability to produce ribitol from a saccharide raw material, producing...
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6346400 |
Process for the preparation of a maltose-rich syrup
The present invention relates to a process for the preparation of a maltose-rich syrup comprising the steps of (a) carrying out liquefaction of a starch milk; (b) carrying out saccharification of...
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6346399 |
Methods for reducing the complexity of DNA sequence
Genomic or cDNA, or fragments and mixtures thereof, can be screened by generation of subsets and then subjecting the subsets to mismatch scanning procedures. Alternatively, DNA fragments can be...
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6294369 |
L-ribose isomerase, its preparation and uses
An L-ribose isomerase which isomerizes aldoses such as L-ribose, D-lyxose, D-talose, D-mannose, L-allose and L-gulose into their corresponding ketoses such as L-ribulose, D-xylulose, D-tagatose,...
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6245505 |
Selective ligation and amplification method
The present invention provides a method for amplifying a specific target nucleic acid sequence. The method comprises (1) forming a reaction mixture comprising: (i) the target sequence; (ii) primers...
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6218116 |
Method and device for treatment by complexing of a liquid medium
A method for determining the presence, in a liquid medium, of a plurality of different nucleic ligands in the free state comprises: (a) providing a support for plural complexing on which are...
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6214628 |
Method of conducting an assay of a sample containing an analyte of interest
In accordance with the present invention, a method of conducting an assay of a sample containing an analyte of interest includes the step of forming a mixture so as to bring a metal-ligand complex...
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6130046 |
Techniques for synthesis integrity evaluation utilizing cycle fidelity probes
Techniques for designing polymer probes to verify the integrity of the probe synthesis are provided. Multiple probes with identical sequences are designed so that the probes will be formed...
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6025168 |
Method for the production of isomalto-oligosaccharide rich syrups
The present invention describes a method for the production of isomalto-oligosaccharides syrups. The method comprises the use of enzymes immobilized on a re-usable carrier. The carrier is...
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5985668 |
Sucrose metabolism mutants
The invention relates to sucrose isomerases, to DNA sequences coding therefor, and to novel processes for producing noncariogenic sugars.
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