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7608435 |
Microorganism producing 5′-xanthylic acid
The invention relates to a microorganism, obtained by treating Corynebacterium ammoniagenes KCCM 10488 producing 5′-Xanthylic acid as parent strain with UV radiation and mutation Derivatives...
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6875591 |
Process for producing GDP-fucose
Processes for producing GDP-fucose, comprising allowing GKDM and a culture broth of a microorganism capable of converting GKDM into GDP-fucose to be present in an aqueous medium, forming and...
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6147211 |
Method for treating cyclic phosphate compound
The invention relates to a compound of formula (I) ##STR1## Wherein: B is adenine, guanine or hypoxanthine Z is hydrogen or a negative charge R is --[CH 2 CH(R 1 )--O] n -R 2 , --CH 2 CH 2 X,...
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6090408 |
Use of polymerized lipid diagnostic agents
Polymerized liposome particles which are linked to a targeting agent and may also be linked to a contrast enhancement agent and/or linked to or encapsulating a treatment agent. The targeting...
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6040158 |
Process for preparing sugar nucleotide
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5968787 |
Process for producing fructose 2,6,-bisphosphate and purification process thereof
This invention relates to a process for the production of fructose 2,6-bisphosphate which comprises effecting reactions among (i) fructose 6-phosphate, (ii) glucose, (iii) fructose or (iv) glucose...
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5919673 |
One-pot enzymatic sulfation process using 3'-phosphoadenosine-5'-phosphosulfate and recycled phosphorylated adenosine intermediates
A process for the enzymatic synthase of sulfate esters is disclosed in which intermediate phosphorylated adenosine compounds are recycled to minimize enzyme inhibition. Exemplary enzymes include...
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5874272 |
Inosine-guanosine kinase
The present invention relates to an inosine-guanosine kinase which catalyzes the reaction of forming 5'-inosinic acid (5'-IMP) from inosine and adenosine triphosphate (ATP) or deoxyadenosine...
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5688940 |
Linker for immobilization, modification and subsequent release of oligomers with a terminal hydroxyl group
The invention is a method which allows the attachment of an alcohol to a substrate by the use of which chemical and/or enzymatic transformations of the alcohol are facilitated, and subsequently the...
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5501965 |
Process for producing fructose 2,6-bisphosphate and purification process thereof
This invention relates to a process for the production of fructose 2,6-bisphosphate which comprises effecting reactions among (i) fructose 6-phosphate, (ii) glucose, (iii) fructose or (iv) glucose...
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5376535 |
Method for producing 3'-phosphoadenosine 5'-phosphosulfate
A method for producing 3'-phosphoadenosine 5'-phosphosulfate, which comprises (1) reacting adenosine 5'-triphosphate with a sulfate donor in the presence of heat-stable adenosine 5'-triphosphate...
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5296473 |
Process for preparing a powder having a high concentration of lactosucrose and use of said powder
The lactosucrose high-content powder according to the present invention is prepared by allowing an aqueous solution containing sucrose and lactose to act on a saccharidetransferring enzyme,...
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5221608 |
Methods for rendering amplified nucleic acid subsequently unamplifiable
Method for treating nucleic acid that is to be amplified such that the nucleic acid is, after amplification, subsequently unamplifiable. Nucleic acid amplification is performed in a reaction...
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5164306 |
Process for producing 5'-inosinic acid by fermentation
A process for producing 5'-inosinic acid by culturing 5'-inosinic acid-producing bacteria in a medium containing inosine, and cane molasses, sucrose or glucose as the main carbon source and...
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5094947 |
Process for producing fructose-1,6-diphosphate
A process for producing fructose-1,6-diphosphate comprising the steps of: (a) enzymatically converting adenosine 5'-diphosphate to adenosine 5'-triphosphate using an acetate kinase-containing...
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5001055 |
Process for producing physiologically active substance
A process for producing a physiologically active substance by a combined enzymatic method is disclosed. In the combined enzymatic method, a reactant solution containing a precursor or precursors...
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4960696 |
Process for producing physiololgically active substance by multienzyme process
A process for converting AMP into ATP which comprises (a) using an enzyme which converts AMP into ADP and has been produced from microorganisms having an optimum growth temperature of 50° C. to...
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4835104 |
Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides
A biological process for producing a 2',3'-dideoxyncleoside from 2',3'-dideoxyuridine is disclosed. The 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin adsorbent.
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4783402 |
Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique
A process for producing a primary or secondary alcohol derivative of a phosopholipid which comprises reacting the phospholipid with a primary or secondary alcohol in the presence of phospholipase DM.
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4782019 |
Enzymatic production of sphingophospholipid derivatives
A process for producing a sphingophospholipid derivative comprising reacting a sphingophospholipid with a specified compound having an alcoholic hydroxyl group selected from the group consisting of...
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4766071 |
Process for regenerating coenzymes
The invention relates to a process for the enzymatic preparation or regeneration of coenzymes selected from the group consisting of ATP, acetyl-CoA, acetyl-phosphate, NAD, NADP, NADH, and NADPH...
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4701285 |
Acyl phosphate salts and their use
This invention consists of the production of a salt of acyl phosphate in an aqueous solution by a process which involves (1) acylation of phosphoric acid (H 3 PO 4 ) with an acid anhydride of the...
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4656128 |
Modified alkaline phosphatase
This invention provides a proteolytically modified alkaline phosphatase which is irreversibly inactivated upon removal of divalent ions. The modified enzyme is particularly useful as a molecular...
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4617268 |
Process for the preparation of adenosine-5'-triphosphate by fermentation
Disclosed in this invention is a process for the preparation of adenosine-5'-triphosphate by means of fermentation, using an adenosine-5-triphosphate-producing bacterium which assimilates methanol.
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4584272 |
Adenylate kinase and process for the production thereof
A heat-resistant adenylate kinase is described whose activity after an incubation in a buffer solution at about 50° C. for about 15 minutes is at least about 80% of the original activity prior to...
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4562149 |
Yeast culture containing S-adenosyl methionine in high concentrations, and process for production of S-adenosyl methionine
A yeast culture containing at least 10% by weight, based on the dry cell, of S-adenosyl methionine; and a process for producing S-adenosyl methionine, which comprises cultivating a yeast having the...
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4554253 |
Apparatus for synthesizing adenosine-5'-triphosphate
An apparatus for converting into ATP which comprises an enzyme reactor, a source of AMP supply, a source of phosphoric acid donator supply, variable fluid sending apparatus, an automatic sampling...
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4464466 |
Process of producing lincomycin nucleotides
Novel and useful ribonucleotides of analogs of the well known antibiotics lincomycin and clindamycin. These ribonucleotides are unexpectedly highly active against Streptococcus hemolyticus and...
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4396713 |
Restriction endonuclease fingerprinting of kinetoplast DNA minicircles
Hemoflagellates are characterized by restriction endonuclease digestion of the mitochondrial DNA to provide for substantial cleavage of the kDNA network. The resulting electrophoretic profile of...
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4383109 |
Lincomycin nucleotides
Novel and useful ribonucleotides of analogs of the well known antibiotics lincomycin and clindamycin. These ribonucleotides are unexpectedly highly active against Streptococcus hemolyticus and...
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4371613 |
Method for producing purine arabinosides
Purine-arabinosides and a method for making purine-arabinosides are disclosed. The method comprises contacting an arabinose donor and a purine source in the presence of an effective amount of...
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4299823 |
Pyrazolo pyrimidine riboside compounds, pharmaceutical compositions and method of use
4-Substituted alkyl-1-α-D-ribofuransylpyrazole-(3,4-d) pyrimidines are active against coccidia in vivo and unlike the 4-methylthio analogue, are non-toxic. Methods for preparing and using the...
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4212941 |
Method for the production of 9-(2-O-acyl-β-D-arabinofuranosyl)adenine compounds
9-(2-O-Acyl-β-D-arabinofuranosyl)adenine compounds and their production by enzymatic removal of the 3-O-acyl and 5-O-acyl groups of a 9-(2,3-di-O-acyl-β-D-arabinofuranosyl)adenine compound or a...
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4209589 |
Enzymatic process for preparing [γ-.sup.32 P]-labeled nucleotides
ATP and other nucleoside triphosphates labeled in the γ-phosphate with 32 P are prepared from L-α-glycerophosphate and their corresponding nucleoside diphosphates by a series of enzymatic...
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4178210 |
Accellular synthesis of cephalosporins
A cephalosporin antibiotic is produced from a precursor comprising the five membered thiazolidine ring and the β lactam moiety characteristics of penicillins by contacting the precursor with a...
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4169011 |
Facile synthesis of 3'-phosphoadenosine 5'-phosphosulfate (PAPS)
3'-Phosphoadenosine 5'-phosphosulfate, also known as PAPS, is useful in establishing sulfate transfer mechanisms in animals and may be produced by a chemical process yielding 68-72% product from a...
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4164444 |
Method for preparing adenosine triphosphate
Acyl phosphate salts suitable for use as phosphate donors in the production of cofactors, such as adenosine triphosphate, are prepared by acylation of phosphoric acid with a ketene, followed by...
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4141972 |
Purine nucleoside 5'-phosphate (mono, di or tri) 3'(2')-diphosphates and processes for their preparation
New purine nucleoside 5'-phosphate (mono, di or tri) 3'(2')-diphosphates and the sodium, lithium and potassium salts thereof are elaborated by the enzymatic transfer of pyrophosphoryl group from...
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4136175 |
Purine nucleotide antiveral composition and methods of use
The nucleotide derivatives of certain 2,6 substituted purines have been discovered to have anti-viral activity. Novel compounds and their pharmaceutically acceptable salts, pharmaceutical...
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4078971 |
Bound, active cellular organelles and method of producing same
Cellular organelles, examples of which are mitochondria, microsomes and chloroplasts, are bound in an active state on a substantially inert and insoluble support surface, examples of which are...
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4028184 |
Process for producing 3',5'-cyclic adenylic acid
A process for producing 3',5'-cyclic adenylic acid in a high yield at a lower price by culturing a strain belonging to the genus selected from the group consisting of Corynebacterium, Arthrobacter...
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3935072 |
Purification of coenzyme A
Coenzyme A is purified by a process involving contacting a cyanogen halide-activated water-insoluble polysaccharide with a cell-free extract of a coenzyme A-producing microorganism to immobilize...
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3925154 |
Method of producing inosine-5'-monophosphate
Inosinic acid is produced more effectively from inosine or hypoxanthine and phosphate ions in the culture broths of hypoxanthine-requiring mutants of Corynebacterium sp. ATCC 21251 than in the...
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3922193 |
Method of producing guanosine-5'-monophosphate
Inosine and hypoxanthine are converted in the presence of phosphate ions to 5'-guanylic acid in good yield in culture media of an artificially induced mutant of Corynebacterium sp. ATCC 21251 which...
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3920519 |
Enzymatic hydrolysis of ribonucleic acid
Ribonucleic acid is hydrolyzed in an aqueous reaction medium into nucleoside 2', 3'-cyclic phosphates and/or nucleoside 3', 5'-cyclic phosphates with intact cells of microorganisms having a...
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3904477 |
Process for producing 3', 5'-cyclic adenylic acid with microorganism
3',5'-Cyclic adenylic acid is produced in a high yield at a lower price by culturing a strain of microorganism belonging to the genus Microbacterium, such as, for example, Microbacterium No. MT-3...
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3883508 |
Process for the preparation of guanosine tetra- and penta-phosphates and products
The chemical synthesis of guanosine 3',5'-bis-diphosphate (Magic Spot I) and guanosine 3'-diphosphate, 5'-triphosphate (Magic Spot II) starting from the readily available guanosine 2',3'-cyclic...
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3854240 |
ISOTOPICALLY LABELLED COMPOUNDS
The micro-organism Anacystis nidulans is used in place of Chlorella for the production of 14 C-labelled nucleosides, nucleotides and amino-acids by growing the micro-organism in a medium...
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3816251 |
PROCESS FOR PRODUCING ADENOSINE-3,5 -CYCLIC MONOPHOSPHORIC ACID BY FERMENTATION
Adenosine-3',5'-cyclic monophosphoric acid is produced by fermentation of a nutrient medium, containing a fluoride, by a microorganism which is capable of producing the nucleotide. The...
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3784444 |
PROCESS FOR PRODUCING 2-SUBSTITUTED 6-AMINO PURINE RIBOTIDES
Ribosyl phosphates of 2-substituted 6-amino purine derivatives are produced by fermentation of an aqueous nutrient medium containing a 2-substituted 6-amino purine derivative or the riboside...
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