Matches 401 - 426 out of 426 < 1 2 3 4 5 6 7 8 9
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5068189 Recombinant DNA vectors encoding a 4"-O-isovaleryl acylase derived from a carbomycin biosynthetic gene, designated carE, for use in streptomyces and other organisms  
The carE gene of Streptomyces thermotolerans has been isolated and used to construct recombinant DNA expression vectors. The carE gene encodes 4"-O-isovaleryl acylase activity important in the...
5015575 Hybrid DNA synthesis of insulin  
Methods and compositions are provided for efficient production of polypeptides having insulin activity. The proinsulin gene is joined to secretion and processing signals for expression and...
5013658 Transposon tagging of genes in transformed plants  
This invention relates to improved methods for transposon tagging as a route to plant gene isolation. The specific improvements comprise efficient means for preselecting plants which have undergone...
4959314 Cysteine-depleted muteins of biologically active proteins  
Muteins of biologically active proteins such as IFN-β and IL-2 in which cysteine residues that are not essential to biological activity have been deleted or replaced with other amino acids to...
4885242 Genes from pichia histidine pathway and uses thereof  
Novel DNA sequences which code for the production of Pichia histidinol dehydrogenase, phosphoribosyl-ATP-cyclohydrase and phosphoribosyl-ATP-pyrophosphohydratase are provided. Novel constructs...
4830969 Process for the rapid and simple isolation of nucleic acids  
A process for the separation from other cellular materials of heat agglomeration resistant water soluble nitrogen containing organic compounds such as plasmids, RNA's, mitochondrial DNA's, viral...
4808537 Methanol inducible genes obtained from pichia and methods of use  
A method for isolating and cloning methanol inducible genes from Pichia is taught. The regulatory regions are useful for the methanol regulated expression of heterologous genes.
4784952 Conferred susceptibility to lambda phage in non-coliform procaryotic hosts  
Vectors suitable for effecting expression of lamB protein in a desired procaryotic host, and methods for their construction, are disclosed. Transformation with these vectors results in the ability...
4761372 Mutant enterotoxin of E. coli  
A plasmid which comprises genes coding for an immunogenic, non-toxic, heat-labile enterotoxin and/or a non-toxic, heat-stable enterotoxin are disclosed. The E. coli containing this plasmid is also...
4740470 Biologically functional molecular chimeras  
Method and compositions are provided for replication and expression of exogenous genes in microorganisms. Plasmids or virus DNA are cleaved to provide linear DNA having ligatable termini, which are...
4731327 Method for stabilizing recombinant DNA molecules and enhancing the expression thereof in strains of Bacillus  
A recombinant DNA molecule, a portion of which includes a vector whose replication is initiated independently of the temperature-sensitive mutant gene of a temperature-sensitive mutant strain of...
4711848 Site specific mutagenesis in alpha-1-antitrypsin  
Methods are provided for producing sites specific mutagenized alpha-1-antitrypsin. Particular mutants are formed having a mutation in the active site of alpha-1-antitrypsin at amino acid position...
4656134 Gene amplification in eukaryotic cells  
Method and compositions are provided for gene amplification. A DNA unit is prepared capable of replication in a eukaryotic host having tandem genes, where the first gene is capable of complementing...
4621061 Plasmid p SG 2 and process for its preparation  
The new streptomyces plasmid p SG 2, having a molecular weight of 9.2 megadaltons, a contour length of 4.58 μm and a molecular length of about 13.8 kilobases, is described, together with its...
4617267 Plasmid pCG1 from Corynebacterium glutamicum  
Disclosed is a novel vector, plasmid pCG1, and a process of producing plasmid pCG1 from Corynebacterium glutamicum.
4582802 Stimulation of enzymatic ligation of DNA by high concentrations of nonspecific polymers  
DNA ligase activity is strongly accelerated in the presence of high concentrations of non-specific polymers, with an accompanying change in product distribution characteristics. The rate of...
4518698 Plasmid and production thereof  
A novel plasmid pATM3 is obtainable from a microorganism belonging to the genus Streptomyces. The plasmid pATM3 is useful as a cloning vector in recombinant DNA work.
4517300 Plasmid pSAN 181  
A novel plasmid, named pSAN 181, has a molecular weight of 5±0.2 megadaltons and single cleavage sites for each of the restriction endonucleases BamHI, PstI, XhoI and BglII, the positions of said...
4506014 Plasmid pAC 1, a process for obtaining it and its use  
Plasmid pAC 1, which is obtained from Acremonium chrysogenum ATCC 14553 and has a contour length of about 6.7 μm and a molecular size of about 20.9 kilobases (=kb), a process for obtaining it and...
4495280 Cloned high signal strength promoters  
Method for preparing high signal strength promoters and terminators and DNA compositions employing such promoters and terminators. T5 phage is cleaved to provide for DNA sequences having intact...
4489160 Plasmid pCG2  
Disclosed is a novel vector, plasmid pCG2, and a process of producing plasmid pCG2 from Corynebacterium glutamicum.
4460688 Plasmid and its use  
Plasmid conferring resistance to streptomycin (Sm R ) and neomycin (Neo R ) upon its host (e.g. a Bacillus, Staphylococcus or Escherichia coli) and which after having taken up a foreign DNA...
4418194 DNA Fragments for forming plasmids  
The present invention relates to novel, broad bacterial host range small plasmid deoxyribonucleic acid rings which serve as cloning vehicles for DNA fragments, particularly those separated from...
4376164 Process for preparing broad host range small plasmid rings as cloning vehicles  
The present invention relates to novel, broad bacterial host range small plasmid deoxyribonucleic acid rings which serve as cloning vehicles for DNA fragments, particularly those separated from...
4273875 Plasmid and process of isolating same  
A novel chemical compound, essentially pure plasmid pUC6, which is obtainable from a biologically pure culture of the microorganism Streptomyces espinosus biotype 23724a, NRRL 11439. The pUC6...
4237224 Process for producing biologically functional molecular chimeras  
Method and compositions are provided for replication and expression of exogenous genes in microorganisms. Plasmids or virus DNA are cleaved to provide linear DNA having ligatable termini to which...
Matches 401 - 426 out of 426 < 1 2 3 4 5 6 7 8 9