|
Match
|
Document |
Document Title |
|
|
7323319 |
RNA containing coenzymes, biotin, or fluorophores, and methods for their preparation and use
Materials and methods for incorporating adenosine derivatives into the 5′ end of transcribed RNA are disclosed. Adenosine derivatives include naturally occurring compounds such as Coenzyme A,...
|
|
|
7270982 |
Helicobacter pylori antigens in blood
The present invention provides methods for detecting Helicobacter pylori ( H. pylori ) DNA and/or fragments thereof in blood. The first method involves extracting DNA from a blood sample,...
|
|
|
7202022 |
Method for identification, separation and quantitative measurement of nucleic acid fragments
The invention relates to a new method for sequence-specific identification, separation and quantitative measurement of nucleic acid fragments. The invention is based on the use of restriction...
|
|
|
7189505 |
Methods of assessing HIV integrase inhibitor therapy
The present invention relates to methods and products for the evaluation of HIV treatment. The methods are based on evaluating molecular events at the HIV integrase resulting in altered therapeutic...
|
|
|
7186507 |
Fluorescent in situ RT-PCR
The present invention describes an in situ reverse transcriptase PCR method in which the background fluorescence is greatly reduced as compared to traditional in situ PCR.
|
|
|
7179590 |
High temperature reverse transcription using mutant DNA polymerases
The present invention relates to improved reverse transcription methods using a modified thermostable DNA polymerases, particularly in a magnesium ion buffer. These methods are particularly useful...
|
|
|
7176002 |
Universal-tagged oligonucleotide primers and methods of use
The present invention relates to universal-tagged oligonucleotide primers, and to methods of using the primers for amplifying the genome.
|
|
|
7163789 |
Cancer diagnosis method
The invention concerns a method for the diagnosis and/or the follow up of the evolution of cancer comprising the analysis of the RNA components of the telomerase enzyme present in the plasma or...
|
|
|
7135302 |
Method for predicting transplant rejection
The present invention relates to a method for predicting whether or not transplant recipients are likely to reject tissue allografts. It is based, at least in part, on the discovery that, based on...
|
|
|
7132238 |
Method of determining a chemotherapeutic regimen based on ERCC1 expression
The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing ERCC1 expression...
|
|
|
7112404 |
Process for high throughput DNA methylation analysis
There is disclosed an improved high-throughput and quantitative process for determining methylation patterns in genomic DNA samples based on amplifying modified nucleic acid, and detecting...
|
|
|
7083922 |
Detection of HIV
The present invention relates to oligonucleotides for use in amplifying and detecting HIV nucleic acid in a sample.
|
|
|
7074558 |
Nucleic acid amplification using an RNA polymerase and DNA/RNA mixed polymer intermediate products
This invention provides for a novel amplification procedure for nucleic acid. The method uses a wild type or mutant RNA polymerase designed to transcribe both deoxyribonucleotides and ribonucleotides.
|
|
|
7052890 |
Transglutaminase gene products
The invention provides a nucleotide sequence comprising at least a portion of the nucleotide sequence of FIG. 10 A, FIG. 6 B or FIG. 10 A or FIG. 10 B; nucleotides which hybridise to the...
|
|
|
7049067 |
Oligonucleotide for detection of HIV-1 and detection method
An oligonucleotide useful for detection of an RNA derived from HIV-1 consisting of at least 10 consecutive bases in any of SEQ ID NOS:1, 2, 4 to 10 and 13 to 17, which can bind to a specific site...
|
|
|
RE39031 |
RNA amplification method requiring only one manipulation step
An RNA amplification method is particularly useful for diagnosing bacterial or viral infections or genetic disorders and for cell typing. The method includes the steps of denaturing a solution...
|
|
|
7005278 |
Method of determining dihydropyrimidine dehydrogenase gene expression
The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing Dihydropyrimidine...
|
|
|
6986988 |
Method for enrichment of natural antisense messenger RNA
A method for enrichment of natural antisense mRNA which involves hybridization of cDNA obtained from sense RNA with cDNA obtained from antisense RNA, followed by DNA polymerase treatment of the...
|
|
|
6982143 |
Normalizing and amplifying RNA
The invention provides methods and compositions for normalizing and amplifying RNA populations. The methods generally comprise the steps of copying message RNA (mRNA) to form first single-stranded...
|
|
|
6955901 |
Multiplex ligatable probe amplification
Described is an improved multiplex ligation-dependent amplification method for detecting the presence and quantification of at least one specific single stranded target nucleic acid sequence in a...
|
|
|
6949634 |
Method for synthesizing cDNA
A method for synthesizing cDNA characterized by performing a reverse transcription reaction in the presence of an enzyme having a reverse transcriptional activity and another enzyme different from...
|
|
|
6924099 |
Biomarkers and assays for carcinogenesis
The present invention relates to carcinogenesis biomarkers produced by phenobarbital-treated rat hepatocytes, nucleic acid molecules that encode carcinogenesis biomarkers or a fragment thereof and...
|
|
|
6892141 |
Primer design system
A primer design system in which DNA nucleotide sequences are obtained from a database comprising a plurality of different DNA nucleotide sequences, and the nucleotide sequences of primers capable...
|
|
|
6890712 |
Cycling DNA/RNA amplification electrochemiluminescent probe assay
This invention relates to an improved process for detecting and quantifying a desired nucleic acid sequence. The process involves synthesizing single stranded RNA, single stranded DNA,...
|
|
|
6887662 |
Oligonucleotides and assemblies thereof useful in the detection of the presence or absence of target nucleic acid sequences in a sample
Oligonucleotides useful in the detection of a nucleic acid target sequence in a sample.
|
|
|
6881537 |
Nucleic acid sequences that can be used as primers and probes in the amplification and detection of all subtypes of HIV-1
The present invention is related to nucleic acid sequences that can be used in the field of virus diagnostics, more specifically the diagnosis of infections with the AIDS causing Human...
|
|
|
6861222 |
Nucleic acid detection using structured probes
Disclosed are compositions and a method for detection of nucleic acid sequences. The disclosed method uses a structured probe to distinguish between sequences. Structured probes are bifunctional...
|
|
|
6855520 |
Cell volume-regulated human kinase h-sgk
The present invention relates to the cloning and characterization of a human serine/threonine kinase (h-sgk: serum and glucocorticoid dependent kinase). The invention furthermore relates to...
|
|
|
6849430 |
PCR-based monitoring in wastewater biotreatment systems
PCR-based monitoring of microorganisms in systems for the biological treatment of wastewater. In particular, measuring both the abundance and expression of indicator/effector genes or gene...
|
|
|
6849429 |
Viral pseudo-capsids including assembly agonists and antagonists
Recombinant hepatitis C virus (HCV) capsid proteins that self-assemble into large spherical virus-like particles structures and viral capsids that include conformational antigenic epitopes are...
|
|
|
6849404 |
Polymerase chain reaction of DNA of which base sequence is completely unidentified
The present invention relates to a process for amplifying DNA of an organism. More particularly, the present invention is directed to a process for amplifying DNA of an organism through Polymerase...
|
|
|
6846632 |
Method for rapidly identifying porcine estrogen receptor marker
A method for rapidly identifying porcine estrogen receptor (ESR) marker comprises using published primers to amplify the target DNA fragment by polymerase chain reaction (PCR). The DNA fragment is...
|
|
|
6841363 |
Preparation of capped mRNA
The invention provides a process for preparing capped mRNAs from an RNA mixture, e.g. whole RNA isolated from a cell or tissue extract, that includes combining in a reaction mixture RNA comprising...
|
|
|
6838244 |
Fluorescent oligonucleotides and uses thereof
Oligonucleotide molecules labeled with a plurality of fluorophores of one or more types embedded in the backbone of said oligonucleotide, wherein at least one of said fluorophores is not located at...
|
|
|
6828139 |
Production of replicative hepatitis C virus
A nucleic acid having a first nucleotide sequence encoding an infectious hepatitis C virus, a second nucleotide sequence encoding a ribozyme, and an inducible promoter operably linked to the first...
|
|
|
6828127 |
Method of amplifying an RNA target sequence using an RNA polymerase functioning preferably on RNA template
Disclosed is a process for transcribing RNA using a nucleotide reagent as the promoter. Such a reagent enables any type of RNA to be transcribed without sequence specification and without protein...
|
|
|
6821734 |
Method for testing nucleic acid sequence
A method for examining nucleotide sequences of a sample includes adding a group of primers of multiple species to a solution containing the sample and simultaneously synthesizing complementary...
|
|
|
6803189 |
Methods for the detection of cervical cancer
The invention provides a wide range of methods and compositions for detecting and treating cervical cancer in an individual. Specifically, the invention provides target cervical cancer-associated...
|
|
|
6777210 |
Method and reagents for inactivating ribonucleases RNase A, RNase I and RNase T1
The present invention is a general method for irreversibly inactivating ribonucleases. Ribonucleases are completely inactivated by treating them with a reducing agent and heat. RNA samples...
|
|
|
6720144 |
Detection of clonal T-cell receptor-&ggr gene rearrangement by PCR/temporal temperature gradient gel electrophoresis (TTGE)
The present invention provides methods and compositions for detecting and analyzing clonal T-cell receptor (TCR) gene rearrangement using temporal temperature gradient gel electrophoresis (TTGE),...
|
|
|
6699670 |
Quantitative assay for the simultaneous detection and speciation of bacterial infections
An adaptation of the real-time PCR assay allows for highly sensitive detection of any eubacterial species with simultaneous speciation. The assay relies on a ‘multiprobe’ design in which a...
|
|
|
6664056 |
Non-invasive prenatal monitoring
Embodiments of the present invention are directed to the detection of fetal or maternal RNA in a blood sample from a pregnant subject, and may involve subjecting the sample to a test for fetal or...
|
|
|
6613515 |
Ovarian tumor sequences and methods of use therefor
Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, portions thereof,...
|
|
|
6605451 |
Methods and devices for multiplexing amplification reactions
The present invention pertains to methods, reagents, compositions, kits, and instruments for use in simultaneously amplifying multiple targets. In particular, this invention is based on the...
|
|
|
6589734 |
Detection of HIV
The present invention related to oligonucleotides for use in amplifying and detecting HIV nucleic acid in a sample.
|
|
|
6586584 |
Sequences and methods for detection of Hepatitis C virus
Primers and probes derived from the 5′ untranslated region of the HCV genome which facilitate detection and/or quantification of all presently known genotypes of HCV. Disclosed sequences may be...
|
|
|
6582938 |
Amplification of nucleic acids
The present invention relates to the amplification of nucleic acids, preferably from mRNA. A primer and promoter are added to a target sequence to be amplified and then the target is amplified in...
|
|
|
6566103 |
Isothermal polymerase chain reaction by cycling the concentration of divalent metal ions
The present invention provides an alternative PCR amplification which does not draw upon the use of thermostable DNA polymerases. It provides means for the controlled manipulation of denaturing...
|
|
|
6566067 |
High fidelity PCR cloning
The present invention describes a methodology for generating high fidelity PCR products, and also cloning of such high fidelity PCR products in a suitable vector. Generation of polymerase-induced...
|
|
|
6566058 |
Assay involving looped nucleic acid
Disclosed is a method of detecting the presence of a nucleic acid target sequence of interest in a sample, comprising the steps of: (a) reacting the sample containing the target sequence of...
|