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7435560 Method for producing purine nucleoside by fermentation  
A microorganism which has a gene encoding an enzyme in which feedback inhibition is desensitized by substitution of one or two amino acids in PRPP amidotransferase encoded by purF of Escherichia...
7335496 Method for producing target substance  
A target substance is produced by culturing a bacterium which has the ability to produce the target substance in a medium to cause accumulation of said target substance in the medium and collecting...
7229797 Enzymatic synthesis of deoxyribonucleosides  
The present invention relates to a method for the in vitro enzymatic synthesis of deoxyribonucleosides and enzymes suitable for this method.
7148042 Method of preparing a guanosine-group compound and an intermediate thereof  
A glyoxal-guanosine-group compound is prepared either by reacting glyoxal-guanine with any one of ribose-1-phosphate and 2-deoxyribose-1-phosphate in the presence of purine nucleoside...
7141396 Method of preparing a guanosine-group compound and an intermediate thereof  
A glyoxal-guanosine-group compound is prepared either by reacting glyoxal-guanine with any one of ribose-1-phosphate and 2-deoxyribose-1-phosphate in the presence of purine nucleoside...
7141397 Method of preparing a guanosine-group compound and an intermediate thereof  
A glyoxal-guanosine-group compound is prepared either by reacting glyoxal-guanine with any one of ribose-1-phosphate and 2-deoxyribose-1-phosphate in the presence of purine nucleoside...
7067261 Methods and compositions for treatment of central nervous system disorders  
The invention provides methods of screening for substances having an effect on a nicotine receptor by contacting a cell having a nicotine receptor with a test substance; and determining any...
7038039 Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside  
A desired isomer is selectively prepared by phosphorolyzing and isomerizing an anomer mixture of a 1-phosphorylated saccharide derivative while crystallizing one of the isomers to displace the...
6777208 Method for producing 2′ -deoxyribonucleoside  
A 2′-deoxyribonucleoside is produced by culturing a microorganism, which is transformed with a gene encoding a ribonucleotide reductase and in which 2′-deoxyribonucleoside degradation activity...
6743910 Stereoselective synthesis of nucleoside analogues  
The invention is a process for stereoselectively producing a dioxolane nucleoside analogue from an anomeric mixture of β and α anomers represented by the following formula A or formula B: ...
6649753 Stable salts of S-adenosyl-L-methionine (SAMe) and the process for their preparation  
This invention relates to the production of new & stable salts of S-adenosyl-L-methionine SAMe). The source of SAMe used in the salt formation is from chemical process wherein stereoselective...
6635615 Stable salts of S-adenosyl-l-methionine  
Stable salts of S-adenosyl-1-methionine with polycations such as chitosan are described. The salts according to the invention are very stable and are valuable for use as active constituents in...
6620596 Method of preparing a guanosine-group compound  
A glyoxal-guanosine-group compound is prepared either by reacting glyoxal-guanine with any one of ribose-1-phosphate and 2-deoxyribose-1-phosphate in the presence of purine nucleoside...
6506896 Use of a pentopyranosyl nucleoside for producing an electronic component, and conjugates of said pentopyranosyl nucleoside  
The invention relates to a pentopyranosylnucleoside of the formula (I) or of the formula (II) their preparation and use for the production of a therapeutic, diagnostic and/or electronic component.
6306647 Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides  
A process for converting uridines to 2',3'-dideoxy-2',3'-didehydrouridines by reacting acetic anhydride with a 2',3'-0-alkoxymethylideneuridine intermediate.
6291215 Inhibitory effects on synthetic and natural colorants on carcinogenes  
A method of reducing the percentage of Epstein-Barr virus genome-carrying cells which exhibit Epstein-Barr virus early antigen induction, where the Epstein-Barr virus genome-carrying cells have...
6197552 Process for preparing 2,6-diaminopurine-2'-deoxyriboside and 2'-deoxyguanosine  
A process for preparing 2,6-diaminopurine-2'-deoxyriboside and 2'-deoxyguanosine. These compounds may be used as materials for pharmaceuticals, such as antiviral agents and the like, and...
6172209 Aminooxy-modified oligonucleotides and methods for making same  
Oligonucleotides and other macromolecules are provided which have increased nuclease resistance, substituent groups (such as 2'-aminooxy groups) for increasing binding affinity to complementary...
6087132 Multi-functional enzymes including derivable 2'3'-dideoxyribofuranoside triprosphates  
The invention relates to a multifunctional nucleoside didesoxyribosyl or nucleoside deoxyribosyl transferase which has one or more of the following additional activities (desoxy) nucleoside kinase,...
6040158 Process for preparing sugar nucleotide  
6017736 Method of preparing purine nucleoside compound  
The present invention provides a method of preparing stably and at a high yield a purine nucleoside compound by utilizing an exchange reaction of a nucleic acid base which is carried out in the...
5851494 Solid phase synthesis reaction vessel and method of using the same  
A solid phase synthesis reaction vessel includes a vessel with a first inlet, a second inlet, and an outlet. A first stopcock is disposed within the first inlet and a second stopcock is disposed...
5821090 Riboflavin-biosynthesis in fungi  
The present invention relates to the genes for riboflavin biosynthesis in the fungus Ashbya gossypii and to genetic engineering processes for preparing riboflavin using these genes and gene products.
5770716 Substituted propargylethoxyamido nucleosides, oligonucleotides and methods for using same  
Substituted propargylethoxyamido nucleosides are disclosed having the structure ##STR1## wherein X is selected from the group consisting of amino alkanoic acid, alkylamino benzoic acid, α-amino...
5714351 Cyclopentenes  
The individual enantiomers of the compounds (Ia), (Ib), (IIa) or (IIb), optionally substituted by non-interfering substituent(s). The novel enantiomers can be obtained by biotransformation. The...
5700666 Process for the production of arabinonucleotides  
A process for the production of arabinonucleotides of general formula I ##STR1## in which X represents a hydrogen atom or a fluorine atom, is described, which is characterized in that an...
5563049 2',3'-dideoxy purine nucleosides and process for the preparation thereof  
2',3'-Dideoxy purine nucleosides represented by following general formulae [I] and/or [II] ##STR1## (wherein X and Y indicate nitrogen atoms or carbon atoms and R 1 , R 2 , R 3 , R 4 and R 5 ...
5506122 Process for producing nucleosides  
The present invention concerns a process for producing nucleosides by carrying out the reaction of a base donor, a saccharide residue donor and a phosphoric acid donor by the use of an enzyme...
5391550 Compositions of matter and methods for increasing intracellular ATP levels and physical performance levels and for increasing the rate of wound repair  
Disclosed are methods and compositions of matter for increasing the intracellular synthesis of ATP. The compositions comprise amino acids, metabolites, electrolyte and/or a pentose sugar. When...
5306629 Method for producing dinucleoside polyphosphate, nucleoside polyphosphate or derivatives thereof  
A method for producing a dinucleoside polyphosphate, a nucleoside polyphosphate or a derivative thereof which comprises using adenosine-5'-triphosphate, polyphosphate or a derivative thereof and a...
5214048 Oxetanocins  
This invention relates to novel oxetanocins represented by the following general formula (I): ##STR1## wherein R represents a group represented by ##STR2## and their pharmacologically acceptable...
5204245 Extraction of thymidine and other nucleosides  
An enzymatic process for extracting a nucleoside, such as thymidine, from a biomass without substantial thymine production.
5164306 Process for producing 5'-inosinic acid by fermentation  
A process for producing 5'-inosinic acid by culturing 5'-inosinic acid-producing bacteria in a medium containing inosine, and cane molasses, sucrose or glucose as the main carbon source and...
5149640 Method for producing galactose transfer products  
A galactose transfer product is prepared by a process of allowing a microorganism capable of producing a galactose transfer product of the formula: (Gal) n --R, wherein Gal represents a galactose...
5137698 Apparatus for carrying out chemical reaction sequences  
An apparatus for carrying out chemical reaction sequences includes a stack of reaction plates arranged one above another and displaceable according to choice step by step in relation to one...
5120645 Production of 2-deoxyuridine  
A process for the preparation of 2-deoxyuridine, which can be used as a nucleus for compositions useful as therapeutic drugs, in which a strain of the genus Brevibacterium is cultivated on a...
5116741 Biosynthetic uses of thermostable proteases  
The invention relates to the novel use of mutants of subtilisin in organic syntheses reactions in non-native environments. Especially the invention relates to methods for the use of mutant...
5075225 Process for the enzymatic synthesis of nucleosides  
A process for synthesizing nucleosides is disclosed. The process includes the reaction of an alkylated nucleoside (such as 7-methylguanosine or 7-methylinosine) with a heterocyclic base (such as...
5053499 2',3'-dideoxy purine nucleoside  
2', 3'-Dideoxy purine nucleosides represented by following general formulae [I] and/or [II] ##STR1## (wherein X and Y indicate nitrogen atoms or carbon atoms and R 1 , R 2 , R 3 , R 4 and R 5 ...
5011774 Dideoxyinosine by enzymatic deamination of dideoxyadenosine  
A novel process utilizing adenosine deaminase to selectively produce β-(D)-2',3'-dideoxyinosine in high yields from an α,β-anomeric mixture. β-(D)-2',3'-Dideoxyinosine so produced is useful as...
5008188 Process for producing S-adenosyl-L-homocysteine  
Process for producing S-adenosyl-L-homocysteine, which comprises reacting adenosine with homocysteine by contacting them in an aqueous medium in the presence of cells or treated cells of a...
4992368 Novel process for producing oxetanocin G  
The present invention provides a novel process for producing oxetanocin G by hydrolysis of alkoxylated 2-amino-oxetanocin A thereby to convert ##STR1## at the 6-position thereof into >CO....
4970148 Method of producing 2',3'-dideoxyinosine  
A method of producing dideoxyinosine involving contacting as a substrate 2',3'-dideoxyadenosine with a microorganism which is capable of converting the substrate into 2',3'-dideoxyinosine.
4960696 Process for producing physiololgically active substance by multienzyme process  
A process for converting AMP into ATP which comprises (a) using an enzyme which converts AMP into ADP and has been produced from microorganisms having an optimum growth temperature of 50° C. to...
4923851 Composition of matter for increasing intracellular ATP levels and physical performance levels and for increasing the rate of wound repair  
A composition of matter for increasing the intracellular synthesis of ATP. The composition consists of amino acids, metabolites, electrolyte and a pentose sugar. When applied to wounds, the...
4914028 Method of preparing beta-2',2'-difluoronucleosides  
A process for preparing β-2',2'-difluoronucleosides, and a novel intermediate thereto, are disclosed.
4904585 Novel antibiotic NK84-0218 and process for the production of the same  
This invention relates to a novel antibiotic NK84-0218 of the formula: ##STR1## which exhibits antibacterial, antiviral and antineo-plastic activities and is expected as a pharmaceutical as well as...
4835104 Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides  
A biological process for producing a 2',3'-dideoxyncleoside from 2',3'-dideoxyuridine is disclosed. The 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin adsorbent.
4749650 Bacillus containing a 5'inosinate dehydrocenase gene  
A DNA having a 5'-inosinate dehydrogenase gene and further having a Hind III cleavage site 2.9 kilo base pairs can be produced from the chromosomal DNA of a guanosine and/or xanthosine-producing...
4743689 Antibiotic derivative of adenine  
This invention relates to a novel antibiotic NK84-0218 of the formula: ##STR1## which exhibits antibacterial, antiviral and antineoplastic activities and is expected as a pharmaceutical as well as...
Matches 1 - 50 out of 120 1 2 3 >