Patents in Class 435/87

Matches 1 - 50 out of 97

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Match	Document	Document Title
1	7608432	Method for producing purine nucleoside by fermentation A microorganism which has a gene encoding an enzyme in which feedback inhibition is desensitized by substitution of one or two amino acids in PRPP amidotransferase encoded by purF of Escherichia...
2	7601519	Method for producing purine nucleoside by fermentation A microorganism which has a gene encoding an enzyme in which feedback inhibition is desensitized by substitution of one or two amino acids in PRPP amidotransferase encoded by purF of Escherichia...
3	7575901	Method for producing nucleotide by fermentation Nucleoside 5′-phosphate ester is produced by culturing a bacterium belonging to the genus Escherichia having an ability to produce nucleoside 5′-phosphate ester, in which ushA gene and aphA...
4	7566545	Method for producing a nucleosome preparation and use thereof in in vitro diagnosis of disseminated lupus erythematosus (DLE) Compositions and methods are provided for decreasing blood glucose levels in an animal or for preventing or delaying the onset of a rise in blood glucose levels in an animal, comprising...
5	7511125	Pyrimidine derivatives for labeled binding partners Compounds having structure (1) wherein R 1 is —H a protecting group, a linker or a binding partner; and R 2 and R 34 are as defined in the specification. The invention also provides...
6	7435560	Method for producing purine nucleoside by fermentation A microorganism which has a gene encoding an enzyme in which feedback inhibition is desensitized by substitution of one or two amino acids in PRPP amidotransferase encoded by purF of Escherichia...
7	7338792	Process for the preparation of D-pantothenic acid and/or salts thereof The invention provides a process for the preparation of D-pantothenic acid and/or salts thereof or feedstuffs additives comprising these by fermentation of microorganisms of the Bacillus group,...
8	7294486	Enzymatic process for the synthesis of organo-fluorine compounds There is described a process for the synthesis of a fluoronucleoside compound, said process comprising mixing a substrate and an enzyme from Streptomyces cattelya as catalyst. The process may be...
9	7270980	Compounds for immunodiagnosis of prostate cancer and methods for their use Compounds and methods for diagnosing prostate cancer are provided. The inventive compounds include polypeptides containing at least a portion of a prostate tumor protein. The inventive polypeptides...
10	7238338	System and method for the large scale labeling of compounds with radiohalogens Disclosed are methods for manufacturing radiohalogen-labeled steroids, nucleosides, nucleotides and proteins, for example, pyrimidines and proteins. Methods according to the example embodiments...
11	7229797	Enzymatic synthesis of deoxyribonucleosides The present invention relates to a method for the in vitro enzymatic synthesis of deoxyribonucleosides and enzymes suitable for this method.
12	7148042	Method of preparing a guanosine-group compound and an intermediate thereof A glyoxal-guanosine-group compound is prepared either by reacting glyoxal-guanine with any one of ribose-1-phosphate and 2-deoxyribose-1-phosphate in the presence of purine nucleoside...
13	7141397	Method of preparing a guanosine-group compound and an intermediate thereof A glyoxal-guanosine-group compound is prepared either by reacting glyoxal-guanine with any one of ribose-1-phosphate and 2-deoxyribose-1-phosphate in the presence of purine nucleoside...
14	7141396	Method of preparing a guanosine-group compound and an intermediate thereof A glyoxal-guanosine-group compound is prepared either by reacting glyoxal-guanine with any one of ribose-1-phosphate and 2-deoxyribose-1-phosphate in the presence of purine nucleoside...
15	7038039	Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside A desired isomer is selectively prepared by phosphorolyzing and isomerizing an anomer mixture of a 1-phosphorylated saccharide derivative while crystallizing one of the isomers to displace the...
16	6974865	C3′ -methylene hydrogen phosphonate oligomers and related compounds The present invention is directed to nucleoside monomers wherein the 3′-O atom is replaced with a methylene group. The present invention also provides oligomers comprising a plurality of such...
17	6900301	Backbone modified oligonucleotide analogues Therapeutic oligonucleotide analogues which have improved nuclease resistance and improved cellular uptake are provided. Replacement of the normal phosphorodiester inter-sugar linkages found in...
18	6890739	Use of uridine diphosphate glucose 4-epimerase The present invention relates to a new use of uridine diphosphate glucose 4-epimerase (also called uridine diphosphate galactose 4-epimerase), and a method of converting uridine diphosphate...
19	6858721	Method for producing cytosine nucleoside compounds The invention provides a method for producing a cytosine nucleoside compound from pentose-1-phosphate and cytosine or a derivative thereof using a nucleoside phosphorylase reactive to cytosine or a...
20	6777208	Method for producing 2′ -deoxyribonucleoside A 2′-deoxyribonucleoside is produced by culturing a microorganism, which is transformed with a gene encoding a ribonucleotide reductase and in which 2′-deoxyribonucleoside degradation activity...
21	6743910	Stereoselective synthesis of nucleoside analogues The invention is a process for stereoselectively producing a dioxolane nucleoside analogue from an anomeric mixture of β and α anomers represented by the following formula A or formula B: ...
22	6649753	Stable salts of S-adenosyl-L-methionine (SAMe) and the process for their preparation This invention relates to the production of new & stable salts of S-adenosyl-L-methionine SAMe). The source of SAMe used in the salt formation is from chemical process wherein stereoselective...
23	6620596	Method of preparing a guanosine-group compound A glyoxal-guanosine-group compound is prepared either by reacting glyoxal-guanine with any one of ribose-1-phosphate and 2-deoxyribose-1-phosphate in the presence of purine nucleoside...
24	6365374	2′-deoxy-2′-alkylnucleotide containing nucleic acid 2′-deoxy-2′-alkylnucleotides useful for stabilizing enzymatic nucleic acid molecules and antisense molecules.
25	6344344	Method for producing uridine-5'-monophosphate by fermentation using mutant strains of coryneform bacteria Uridine-5′-monophosphate is produced by cultivating in a nutrient medium an uridine-5′-monophosphate producing mutant of coryneform bacterium and which is characterized by at least a resistance...
26	6316228	Efficient synthesis of nucleosides Methods and compositions, including cell cultures, for producing nucleosides are provided which comprise contacting a nucleoside precursor and a sugar moiety donor with a cell containing a...
27	6268183	Method of purifying thuringiensin The invention discloses a two-step process for recovery of thuringiensin, comprising adsorbing the thuringiensin from fermentation broth by calcium silicate, and dissociating the thuringiensin by...
28	6197552	Process for preparing 2,6-diaminopurine-2'-deoxyriboside and 2'-deoxyguanosine A process for preparing 2,6-diaminopurine-2'-deoxyriboside and 2'-deoxyguanosine. These compounds may be used as materials for pharmaceuticals, such as antiviral agents and the like, and...
29	6127152	Process for producing nucleoside derivatives There is disclosed a process for producing a nucleoside derivative of the formula [I]: ##STR1## characterized by contacting 2',3',5'-O-triacylribonucleoside derivative of the formula [II]: ##STR2##...
30	6087132	Multi-functional enzymes including derivable 2'3'-dideoxyribofuranoside triprosphates The invention relates to a multifunctional nucleoside didesoxyribosyl or nucleoside deoxyribosyl transferase which has one or more of the following additional activities (desoxy) nucleoside kinase,...
31	6017736	Method of preparing purine nucleoside compound The present invention provides a method of preparing stably and at a high yield a purine nucleoside compound by utilizing an exchange reaction of a nucleic acid base which is carried out in the...
32	5888777	Process for the complete removal of protective groups on nucleoside diphosphate and triphosphate sugars with acetylesterase A process for the preparation of nucleoside diphosphate and triphosphate sugars wherein hydroxyl protective groups are removed enzymatically, with acetylesterase and a process for the preparation...
33	5859235	Dipteran-active uracil derivative The invention relates to a novel substance with activity against insect pests of the order Diptera. The invention further relates to the substance which acts together with a Bacillus related...
34	5851494	Solid phase synthesis reaction vessel and method of using the same A solid phase synthesis reaction vessel includes a vessel with a first inlet, a second inlet, and an outlet. A first stopcock is disposed within the first inlet and a second stopcock is disposed...
35	5773228	Activation-dependent protein expressed on the surface of activated platelets and antibodies thereto The present invention provides a thrombin-activated platelet protein (TAPP). The protein is selectively expressed on the surface of thrombin-activated platelets. Antibodies which selectively bind...
36	5770716	Substituted propargylethoxyamido nucleosides, oligonucleotides and methods for using same Substituted propargylethoxyamido nucleosides are disclosed having the structure ##STR1## wherein X is selected from the group consisting of amino alkanoic acid, alkylamino benzoic acid, α-amino...
37	5714351	Cyclopentenes The individual enantiomers of the compounds (Ia), (Ib), (IIa) or (IIb), optionally substituted by non-interfering substituent(s). The novel enantiomers can be obtained by biotransformation. The...
38	5547858	Method for purification of amino acids, nucleic acids using a hydrocyclone Crystals of an amino acid, a nucleic acid or a derivative thereof can be efficiently isolated and purified at low cost from a solution containing the crystals, bacterial cells and medium components...
39	5547857	Process for producing 5-methyluridine and purification by sedimentation velocity The present provides a process for obtaining high-purity 5-methyluridine crystals from nucleic acid ingredients as starting materials using a microorganism. The process comprises culturing a...
40	5506122	Process for producing nucleosides The present invention concerns a process for producing nucleosides by carrying out the reaction of a base donor, a saccharide residue donor and a phosphoric acid donor by the use of an enzyme...
41	5468849	Rebeccamycin analogs by tryptophan analogs feeding Addition of certain tryptophan analogs to the culture medium during fermentation of a rebeccamycin-producing strain of Saccharothrix aerocolonigenes results in production of new rebeccamycin...
42	5463035	Process for purifying pentostatin A process for purifying pentostatin from a crude fermentation beer comprising the steps of 1) applying the fermentation beer to a strong cation exchange resin; 2) eluting with ammonium hydroxide;...
43	5391550	Compositions of matter and methods for increasing intracellular ATP levels and physical performance levels and for increasing the rate of wound repair Disclosed are methods and compositions of matter for increasing the intracellular synthesis of ATP. The compositions comprise amino acids, metabolites, electrolyte and/or a pentose sugar. When...
44	5356772	Process for preparing an improved western blot immunoassay The present invention encompasses an improved immunoassay method which involves the simultaneous transfer of multiple antigens onto a single solid support. The antigens which may be utilized by...
45	5306629	Method for producing dinucleoside polyphosphate, nucleoside polyphosphate or derivatives thereof A method for producing a dinucleoside polyphosphate, a nucleoside polyphosphate or a derivative thereof which comprises using adenosine-5'-triphosphate, polyphosphate or a derivative thereof and a...
46	5288606	Reagent for specific determination of fructosamine The present invention provides a process for the specific determination of the serum fructosamine content in blood or samples derived from blood by reaction with an appropriate color reagent and...
47	5204245	Extraction of thymidine and other nucleosides An enzymatic process for extracting a nucleoside, such as thymidine, from a biomass without substantial thymine production.
48	5169759	Removal of riboflavin from fermentation suspensions Riboflavin is removed from fermentation suspensions by them being heated at from 50° to 90° C. for from 1 to 3 hours, than cooled to from 0° to 30° C. over a period of from 1 to 5 hours, and...
49	5166327	Process for producing 3'-deoxy-3-'-fluorothymidine This invention provides a process for producing 3'-deoxy-'-fluorothymidine, which comprises allowing 3'-deoxy-'-fluoro-5'-mesylthymidine (the stating material) to react with an acetylating agent,...
50	5158938	Rebeccamycin Addition of bromine to the culture medium during fermentation of a rebeccamycin-producing strain of Saccharothrix aerocolonigenes results in production of a new rebeccamycin derivative having...

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