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8999671 Production of sialylated N-glycans in lower eukaryotes  
The present invention relates to eukaryotic host cells which have been modified to produce sialylated glycoproteins by the heterologous expression of a set of glycosyltransferases, including...
8986973 Streptococcus dysgalactiae ID9103 and method for production of hyaluronic acid using the same  
Provided is a Streptococcus dysgalactiae ID9103 strain having accession number KCTC11818BP, and a method of producing hyaluronic acid by culturing the strain to produce hyaluronic acid having an...
8975043 Enzymatic degradation of lipid A fatty acids of bacterial LPS  
Novel enzymes, processes and antigenic structures useful in producing vaccines and compounds useful in combating gram-negative bacteria are described. Enzymes were isolated from the slime mold...
8927234 Method for producing hyaluronic acid  
It is intended to provide a simple method for producing hyaluronic acid at a high yield. Further, it is also intended to provide a method for producing hyaluronic acid in a short period of time....
8883452 K5 heparosan fermentation and purification  
A method for the production of heparosan from fermentation culture of E. coli K5 suitable for industrial production, exhibiting superior yield and purity, smaller culture volumes, faster growth,...
8852891 N-acetylglucosamine-2-epimerase and method for producing CMP-neuraminic acid using the same  
The present invention relates to a novel N-acetylglucosamine-2-epimerase and a method for preparing CMP-N-acetylneuraminic acid, more specifically, relates to a N-acetylglucosamine-2-epimerase...
8778636 Chemo-enzymatic approach to the synthesis of pimecrolimus  
Processes for preparing pimecrolimus starting from ascomycin, exploiting the selectivity characteristics of the purified enzymatic systems particularly regarding the selective functionalization of...
8771992 Biotechnological production of chondroitin  
Chondroitin is produced by culturing a recombinant microorganism which is obtained by inactivation of a gene encoding an enzyme responsible for addition of fructose residues to the linear...
8759033 CSNR-deficient actinobacteria for the production of an enzyme having chitosanase activity  
The present invention relates to genetically modified actinobacteria for the production of an enzyme having chitosanase activity. The genetically modified actinobacteria have a reduced (or...
8735102 Hyaluronan synthase genes and expression thereof in Bacillus hosts  
The present invention relates to a recombinant Bacillus host cell containing a recombinant vector including a nucleic acid segment having a coding region segment encoding enzymatically active...
8722365 Metabolically engineered Escherichia coli for enhanced production of sialic acid  
A metabolically engineered E. coli strain which produces sialic acid and a method of making said strain. In the engineered E. coli cells, the nanT (sialic acid transporter) and nanA (sialic acid...
8722366 Methods for synthesizing sugar chains using β1,3-N-acetylglucosaminyltransferase  
The present invention provides a novel polypeptide having a β1,3-N-acetylglucosaminyltransferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a...
8697398 Compositions and methods for bacterial production of chondroitin  
The invention relates to the field of recombinant DNA technology for the production of chondroitin, including the production of chondroitin sulfate via a combination of recombinant bacterial...
8685673 Method for producing indole derivative  
The present invention provides a method for in vitro producing an indole derivative in a one-pot reaction. The method for producing a rhamnosylated indolocarbazole compound includes the steps of...
8685674 Chondroitin synthase, method for producing the same and method for producing saccharide chain-extended chondroitin  
A vector of the present invention has DNA encoding a protein or a product having the same effect as the protein, the protein containing an amino acid sequence from amino acid numbers 47 to 802 in...
8586332 Method for producing oligopolysaccharides  
The invention concerns the production by microbiological process of oligopolysaccharides of biological interest. More particularly, the invention concerns a method for synthesizing in vivo the...
8574886 Methods for producing hyaluronan in a recombinant host cell  
The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a Bacillus host cell under conditions suitable for production of the hyaluronic acid, wherein...
8551736 Inosine producing microorganism belonging to the genus Corynebacterium and process of producing inosine using the same  
A microorganism of the genus Corynebacterium having the ability to produce inosine in which the inosine catabolic pathway is blocked and that has a leaky adenine auxotrophic phenotype and further...
8507227 Method of producing sialylated oligosaccharides  
The present invention relates to a method for the large scale in vivo synthesis of sialylated oligosaccharides, culturing a microorganism in a culture medium, optionally comprising an exogenous...
8466127 Pegylated and fatty acid grafted chitosan oligosaccharide, synthesis method and application for drug delivery system  
The present invention provides a PEGylated and fatty acid grafted chitosan oligosaccharide comprising a structural unit represented by the following Formula (I) and a structural unit represented...
8450088 Process for producing CMP-N-acetylneuraminic acid  
A method by which high-purity CMP-N-acetylneuraminic acid (HPLC purity, 95% or higher), which has been difficult to obtain with any technique other than chromatography, can be easily obtained in...
8431365 β1,3-N-acetyl-D-galactosamine transferase protein, nucleic acid encoding the same and method of examining canceration using the same  
The N-acetyl-D-galactosamine transferase protein of the present invention is characterized by transferring N-acetyl-D-galactosamine to N-acetyl-D-glucosamine with β1,3 linkage, and it preferably...
8404461 Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester  
Disclosed is a method for the preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl esters, comprising the enantioselective enzyme reduction of a 1-aryl-2-tetrazolyl-ethyl ketone to form a...
8383368 Method for fermentative production of N-acetyl-D-glucosamine by microorganism  
N-Acetyl-D-glucosamine can be produced by cultivating a fungus capable of producing N-acetyl-D-glucosamine, such as Trichoderma hamatum AB 10282 strain (FERM BP-10623) or Trichoderma harzianum...
8334115 Chondroitin synthase, method for producing the same and method for producing saccharide chain-extended chondroitin  
A vector of the present invention has DNA encoding a protein or a product having the same effect as the protein, the protein containing an amino acid sequence from amino acid numbers 47 to 802 in...
8263332 Mismatched end DNA ligase  
A mismatched end DNA ligase is provided, which ligates two single strands to each other at a high efficiency, even if the other two single strands are not compatible. In one embodiment, the...
8257949 Self-priming polysialyltransferase  
The invention relates to a fusion protein comprising a bifunctional sialytransferase and a poly-sialytransferase and methods to use the fusion proteins for production of poly-sialylated end...
8227213 β1,3-N-acetyl-D-galactosamine transferase protein, nucleic acid encoding the same and method of examining canceration using the same  
The N-acetyl-D-galactosamine transferase protein of the present invention is characterized by transferring N-acetyl-D-galactosamine to N-acetyl-D-glucosamine with β1,3 linkage, and it preferably...
8202705 Sialyltransferase and DNA encoding the same  
A sialyltransferase having the following physico-chemical properties: (1) Activity: transfers sialic acid from a sialic acid donor selectively to a 3-hydroxyl group of a galactose residue...
8148112 Sugar chain containing 4-position halogenated galactose and application thereof  
The present invention is directed to, for example, an oligosaccharide having at an end thereof a 4-position halogenated galactose residue represented by formula (I): (wherein X represents a...
8148113 Method for producing glucosamine by culturing microorganism with low-cost medium  
A method for producing glucosamine with microorganism comprises of fermenting with a microorganism selected from the group consisting of Monascus pilosus and Aspergillus sp. in a novel low-cost...
8137951 Methods for producing hyaluronan in a recombinant host cell  
The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a Bacillus host cell under conditions suitable for production of the hyaluronic acid, wherein...
8129147 Meningococcal oligosaccharide linked polysaccharides and diptheria protein conjugate vaccine for all ages  
Methods for producing quadrivalent meningococcal meningitis polysaccharide and conjugate vaccines for serotypes A, C, Y and W-135 disclosed. Neisseria meningitidis fastidious medium was designed...
8129148 Process for preparation of chondroitin fraction  
Provided are a method for producing a fraction containing more than 50% of CH represented by the general formula (1), which comprises at least the step of allowing a glucuronic acid donor, an...
8124381 Process and materials for production of glucosamine and N-acetylglucosamine  
A biosynthetic method for producing glucosamine and N-acetylglucosamine is disclosed. Such a method includes the fermentation of a genetically modified microorganism to produce glucosamine and/or...
8097437 Highly pure polysialic acid and process for preparation thereof  
The instant invention provides highly pure Polysialic acid and process for preparation thereof.
8093036 Methods for producing hyaluronan in a recombinant host cell  
The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a Bacillus host cell under conditions suitable for production of the hyaluronic acid, wherein...
8093061 Methods of determining potency of chemically-synthesized oligonucleotides  
Provided herein are methods for determining potency of RNAi agents. Such methods include, but are not limited to, cell-based and cell-free assays that measure binding of an RNAi agent with Ago2 or...
7972815 Method of producing sugar chain using human G4 polypeptide  
The present invention provides a novel polypeptide having a β1,3-N-acetylglucosaminyl transferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a...
7955825 Process for producing CMP-N-acetylneuraminic acid  
The present invention is directed to a process for producing CMP-N-acetylneuraminic acid (CMP-NeuAc), comprising adding to the cultured E. coli cells which has been transformed with both the DNA...
7910304 Random array DNA analysis by hybridization  
The invention relates to methods and devices for analyzing single molecules, i.e. nucleic acids. Such single molecules may be derived from natural samples, such as cells, tissues, soil, air and...
7901912 Method of producing uridine 5′-diphospho-N-acetylgalactosamine  
The present invention provides a method for enzymatically producing uridine 5′-diphospho-N-acetylgalactosamine (UDP-GalNAc) (which is an important substrate for oligosaccharide synthesis) from...
7863020 Production of sialylated N-glycans in lower eukaryotes  
The present invention relates to eukaryotic host cells which have been modified to produce sialylated glycoproteins by the heterologous expression of a set of glycosyltransferases, including...
7820422 Efficient production of oligosaccharides using metabolically engineered microorganisms  
The present invention relates to the enzymatic synthesis of oligosaccharides, particularly, sialylated oligosaccharides comprising the carbohydrate moeities of the gangliosides GM3, GD3, and GT3.
7811806 Methods for producing hyaluronan in a recombinant host cell  
The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a Bacillus host cell under conditions suitable for production of the hyaluronic acid, wherein...
7785841 Methods for the early diagnosis of ovarian cancer  
The disclosed nucleic acid primer sets, used in combination with quantitative amplification (PCR) of tissue cDNA, can indicate the presence of specific proteases in a tissue sample. Specifically,...
7776565 Engineering intracellular sialylation pathways  
Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using...
7767394 Nucleotide compositions and uses thereof  
The present invention relates to preparation of nucleotide compositions and uses thereof for conducting nucleic acid analyses. The compositions and methods embodied in the present invention are...
7723080 Murine α (1,3) fucosyltransferase Fuc-TVII, DNA encoding the same, method for preparing the same, antibodies recognizing the same, immunoassays for detecting the same, plasmids containing such DNA, and cells containing such a plasmid  
A gene which encodes a murine leukocyte α(1,3)fucosyltransferase capable of synthesizing the sialyl Lewis x determinant has been cloned.
7622291 Agarase and gene thereof  
Production of efficiently producing agaro-oligosaccharide; a polypeptide having an agarase activity which is usable in, for example, efficiently extracting a substance such as a nucleic acid from...
Matches 1 - 50 out of 208 1 2 3 4 5 >