|
Match
|
Document |
Document Title |
|
|
7413886 |
Process for producing phosphorylase
It is intended to provide a process for conveniently producing phosphorylase at a high purity using a phosphorylase-producing microorganism. Namely, a process for producing phosphorylase...
|
|
|
7413877 |
Bacterial expression of bowman-birk protease inhibitors and variants thereof
The present invention provides compositions and methods related to the expression of Bowman-Birk protease inhibitors and variants thereof in bacterial species. The present invention further...
|
|
|
7410788 |
Compositions and methods for production of disulfide bond containing proteins in host cells
The invention provides composition and methods for producing proteins of interest which comprise at least one disulfide bond, include proteins which in their mature form do not contain disulfide...
|
|
|
7407791 |
Production of secreted polypeptides
Described herein are methods and compositions for the production and secretion of polypeptides. Included herein is the use of interrupting peptide transport activity for an increase in polypeptide...
|
|
|
7405060 |
Gene amplification methods
The present invention provides multivalent vaccines for the treatment of B-cell malignancies (e.g., lymphomas and leukemias). The present invention also provides methods for the production of...
|
|
|
7402417 |
P450 oxygenases and methods of use
This disclosure provides the nucleic acid and protein sequences of novel P450 oxygenases that utilize, at least, taxoid substrates, including taxadiene isomers. The disclosed oxygenases, such as a...
|
|
|
7402419 |
Phosphite dehydrogenase mutants for nicotinamide cofactor regeneration
Phosphite dehydrogenase mutant enzymes were generated that provide relaxed cofactor specificity and increased thermostability over the wild type enzyme. The mutant enzymes are useful for...
|
|
|
7399612 |
VEGF-binding fusion proteins and nucleic acids encoding the same
Nucleic acid molecules encoding fusion proteins which bind and inhibit vascular endothelial growth factor (VEGF). The VEGF-binding fusion proteins are therapeutically useful for treating...
|
|
|
7399615 |
Animal component free meningococcal polysaccharide fermentation and seedbank development
Animal-free meninge fermentation media and process is developed based upon use of a chemically defined medium. To improve polysaccharide production, fed-batch fermentation is examined using...
|
|
|
7396665 |
Method of producing FR901228
Depsipeptides and congeners thereof are disclosed having structure (I), wherein m, n, p, q, X, R1, R2 and R3 are as defined herein. These compounds, including FR901228, have activity as, for...
|
|
|
7393660 |
CC-chemokine binding tick proteins
A novel CC-chemokine binding protein is isolated from the saliva of Rhipicephalus sanguineus . Compounds prepared in accordance with the present invention can be used as anti-inflammatory...
|
|
|
7390633 |
Methods for preparing low molecular weight heparin with modified heparinase III
The invention relates to heparinase III and mutants thereof. Modified forms of heparinase III having reduced enzymatic activity which are useful for a variety of purposes, including sequencing of...
|
|
|
7384767 |
Nucleic acid encoding an interleukin-9 receptor variant
This invention relates to the diagnosis, treatment and methods for discovery of new therapeutics for atopic asthma and related disorders based on variants of Asthma Associated Factor 2. One...
|
|
|
7384771 |
Beta 1,4-N-acetylgalactosaminyltransferases from C. jejuni
This invention provides prokaryotic β1,4-N-acetylgucosaminyl (GalNAc) transferases involved in synthesis of lipooligosaccharide (LOS). The β1,4-GalNAc transferases can be obtained from, for...
|
|
|
7381545 |
Method for controlling metallophosphate precipitation in high cell density fermentations
The invention relates to the use of a phosphate glass as a phosphorous source in the media of high cell density bacterial fermentation processes in order to reduce metallophosphate precipitation...
|
|
|
7378257 |
Bacterial superantigen vaccines
The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an...
|
|
|
7374917 |
Mutant 2.5-diketo-L-gluconic acid reductases
Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated...
|
|
|
7375205 |
Elongase genes and uses thereof
The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated fatty acids (i.e., “elongases”) and to uses thereof. At least two of these...
|
|
|
7371821 |
Cloning and expression of the full length 110 kDa antigen of Orientia tsutsugamushi to be used as a vaccine component against scrub typhus
The inventive subject matter relates to a recombinant 110 kDa protein from O. tsutsugamuchi , Karp, Kato and Gilliam strains and for a DNA expression system containing DNA encoding the 110 kDa...
|
|
|
7371838 |
Nucleic acids encoding β 1,4-N-acetylgalactosaminyltransferases from C. jejuni
This invention provides prokaryotic β1,4-N-acetylglucosaminyl (GalNAc) traosferases involved in synthesis of lipooligosaccharide (LOS). The β1,4-GalNAc transferases can be obtained from, for...
|
|
|
7371824 |
PRO6093 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
|
|
|
7368547 |
Use of novel virulence-specific genes as targets for diagnosis and potential control of virulent strains of Listeria monocytogenes
A method for identifying virulent strains of L. monocytogenes that includes the use of primers or probes in a PCR assay or hybridization technique that employs primers or probes, which are...
|
|
|
7368272 |
Expression of proteolytic enzymes in koji mold in the presence of carbon sources
The present invention refers to a koji mold capable of expressing proteolytic enzymes in the presence of a carbon source in at least the same amount as in the absence thereof. In particular, the...
|
|
|
7368261 |
Conserved Neisserial antigens
To ensure maximum cross-strain recognition and reactivity, regions of proteins that are conserved between different Neisserial species, serogroups and strains can be used. The invention provides...
|
|
|
7365157 |
PRO9912 polypeptides
The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
|
|
|
7365184 |
B. anthracis prevention and treatment: mutant B. anthracis lacking luxS activity and furanone inhibition of growth, AI-2 quorum sensing, and toxin production
The present invention pertains to the discovery that B. anthracis possesses a luxS gene that encodes a functional LuxS polypeptide, and that B. anthracis synthesizes a functional AI-2...
|
|
|
7364724 |
Recombinant super-compound interferon
This invention provides a recombinant super-compound interferon or an equivalent thereof with changed spatial configuration. The super-compound interferon possesses anti-viral or anti-tumor...
|
|
|
7361348 |
Immunogenic glycopeptides, screening, preparation and uses
The invention concerns immunogenic glycopeptides derived from pathogenic microorganisms, useful for vaccination and diagnosis of infections caused by said pathogenic microorganisms (bacteria or...
|
|
|
7361738 |
Megakaryocyte stimulating factors
Novel polypeptides of human megakaryocyte stimulating factors (MSFs). Pharmaceutical compositions containing same, and methods for their preparation and use are provided.
|
|
|
7358355 |
Antibodies against human parathyroid hormone related protein
Disclosed are an antibody against human para-thyroid-hormone-related protein, a DNA coding for the antibody, a recombinant vector containing the DNA, a transformant transformed with the recombinant...
|
|
|
7358074 |
Human phosphatase RET31, and variants thereof
The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant...
|
|
|
7354740 |
Animal product free system and process for purifying a botulinum toxin
Chromatographic processes and systems for purifying a botulinum toxin from an APF fermentation medium.
|
|
|
7351555 |
Mouse cytokine receptor Zcytor16
Cytokines and their receptors have proven usefulness in both basic research, animal models, and as therapeutics. The present invention provides a new cytokine receptor designated as “mouse...
|
|
|
7351550 |
Exoenzyme toxin of Aeromonas salmonicida, and uses thereof
A protein toxin named Aeromonas salmonicida exoenzyme T (AcxT), which belongs to the family of ADP-ribosylating toxins, is disclosed as is a Calcium (or other cation concentration) dependent...
|
|
|
7348015 |
Antigen modified cancer cell vaccines for cancer therapy
Disclosed are methods for treating cancers, particularly tumorigenic types. Cancer cells are modified to express highly immunogenic antigens so that the cells will generate a defensive response in...
|
|
|
7347995 |
Compositions and methods for achieving immune suppression
Disclosed herein are therapeutic compositions containing agents that modulate the immune response in a patient.
|
|
|
7344880 |
Nucleic acid encoding PRO9912 polypeptides
The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
|
|
|
7344856 |
Method of controlling cleavage by OmpT protease
Methods of using OmpT protease are provided. In particular, the invention provides for a method of controlling cleavage of a polypeptide by OmpT protease comprising, converting a sequence site...
|
|
|
7339037 |
Glycosylation-resistant cyanovirins and related conjugates, compositions, nucleic acids, vectors, host cells, methods of production and methods of using nonglycosylated cyanovirins
The invention provides a method of inhibiting prophylactically or therapeutically an influenza viral infection in a host. The method comprises instilling into or onto a host a cell producing an...
|
|
|
7335495 |
Process for the isolation of pharmaceutical compound cyclosporin a from fungus fusarium nivale
The present invention describes the development and standardization of a facile method for the isolation and purification of cyclosporin A from a new source, viz., Fusarium nivale and evaluation...
|
|
|
7335504 |
Engineered enzymes and uses thereof
The present invention provides engineered enzymes generated from protein scaffolds combined with Specificity Determining Regions, the production thereof and the use of said engineered enzymes for...
|
|
|
7332316 |
Plant cytokinin oxidase
The present invention relates to methods for stimulating root growth and/or enhancing the formation of lateral or adventitious roots and/or altering root geotropism comprising expression of a plant...
|
|
|
7332322 |
Venezuelan equine encephalitis virus replicons with adaptive mutations in the genome and uses thereof
The present invention provides a Venezuelan equine encephalitis virus replicon RNA useful in the development of stable lines of mammalian, avian and insect cells in which these replicons will...
|
|
|
7329518 |
Enzyme for producing optically active pyridineethanol derivatives
The present invention relates to a method of producing an optically active pyridineethanol derivative. More particularly, it relates to a method of producing an optically active polycyclic...
|
|
|
7329513 |
High level constitutive production of anthrax protective antigen
The present invention relates to a process for preparing anthrax protective antigen protein from E. coli using fed batch culture. This process creates a constitutively expressing system for...
|
|
|
7329527 |
Serine proteases from gram-positive microorganisms
The present invention relates to the identification of novel serine proteases in Gram-positive microorganisms. The present invention provides the nuclei acid and amino acid sequences for the ...
|
|
|
7329523 |
Phosphoserine phosphatase of coryneform bacteria and variants thereof
The present invention provides a DNA coding for a protein defined in the following (A) or (B) is obtained from Brevibacterium flavum chromosomal DNA library by cloning a DNA fragment that...
|
|
|
7326782 |
Metabolic engineering of viomycin biosynthesis
The invention provides a nucleic acid molecule comprising at least a functional fragment of the viomycin biosynthetic gene cluster, functional proteins encoded by the cluster, expression cassettes...
|
|
|
7323558 |
Nucleic acids encoding dendritic cell transmembrane serine protease
Isolated Dendritic Cell Transmembrane Serine Proteases (DCTSPs), DNAs encoding such DCTSPs, and pharmaceutical and/or diagnostic compositions made therefrom, are disclosed. The isolated DCTSPs can...
|
|
|
7320794 |
Transporter protein
A novel protein which has an activity to transport hydantoin compounds is described, as well as a recombinant expressing this transporter protein. From Microbacterium liquefaciens strain AJ3912,...
|