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7425622 Antibodies against C3a receptor  
The present invention relates to antibodies and related molecules that specifically bind to C3a Receptor. Such antibodies have uses, for example, in the prevention and treatment of asthma,...
7410771 Reagent and method for detecting a Cryptosporidium parvum sporozoite antigen  
A reagent and method for the specific and highly sensitive detection of C. parvum in which the reagent is an antibody for a soluble C. parvum sporozoite antigen and the method is an immunoassay in...
7411050 Monoclonal blocking antibody to human RANKL  
Disclosed herein are kits for detecting RANKL protein or nucleic acids, the kits comprising isolated human RANKL polypeptides, RANKL nucleic acids and/or antibodies specific for RANKL.
7411045 Autocrine growth factor receptor antibodies and methods  
Disclosed herein are antitumor compositions and methods of interfering with the biological activity of PC cell derived growth factor (PCDGF), anti-PCDGF receptor antibodies, fragments thereof, and...
7407743 Kit and method of screening wilson's disease  
The present invention relates to a method for measuring a ceruloplasmin concentration, and more particularly, to a method for measuring a ceruloplasmin in a blood spot based on a standard...
7405061 Antigen PIPA and antibodies that bind thereto  
Provided herein is disclosure about the identification and characterization of disease and cancer associated antigen PIPA. The invention also provides a family of monoclonal antibodies that bind...
7402409 Cell fusion method  
The invention provides methods for fusing a first cell with a second cell to form a hybrid cell. The methods involve incubating a first parental cell producing a first partner of a fusogenic...
7393650 Method of producing an antibody to G-protein parathyroid hormone receptor HLTDG74  
Human G-protein parathyroid hormone (PTH) receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed....
7390489 Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody  
The present invention relates to a monoclonal antibody binding specifically to the p60 protein of Listeria monocytogenes, a hybridoma cell producing the monoclonal antibody, a test kit comprising...
7387873 Human myeloma cell line  
There is provided a human myeloma cell tine for use in a method for producing a human monoclonal antibody.
7384632 Agonist anti-trk-C monoclonal antibodies  
The invention concerns agonist anti-trkC monoclonal antoibodies which mimic certain biological activities of NT-3, the native ligand of trkC. The invention further concerns the use of such...
7381412 Anti-TECK antibodies and methods of use therefor  
The invention relates to antibodies or antigen-binding fragments thereof which binds the chemokine mammalian TECK and inhibit binding of the chemokine to mammalian GPR-9-6. The invention also...
7361341 Methods of treating cancer using antibodies that immunospecifically bind to trail receptors  
The present invention relates to antibodies and related molecules that immunospecifically bind to TRAIL receptor, TR4. Such antibodies have uses, for example, in the treatment of cancers and other...
7335748 RG1 antibodies and uses thereof  
The present invention relates to antibodies, and antigen-binding antibody fragments, directed against an RG1 polypeptide. The invention further relates to methods for utilizing the antibodies, and...
7329738 Assays for detection of Bacillus anthracis  
This invention provides novel methods, reagents, and kits that are useful for detecting B. anthracis. The methods are based on the discovery of binding agents, including recombinant polyclonal...
7321026 Framework-patched immunoglobulins  
Framework (FR)-patching is a novel approach to modify immunoglobulin for reducing potential immunogenicity without significant alterations in specificity and affinity. Unlike previous described...
7314621 Cytidine deaminase  
Antibodies that specifically bind to AID (Activation-Induced cytidine Deaminase) proteins, compositions comprising said antibodies, and cells producing said antibodies, are described. The AID...
7279561 Anti-rapamycin monoclonal antibodies  
Provided are rapamycin conjugates which are useful as immunogenic molecules for the generation of antibodies specific for rapamycin, for measuring levels of rapamycin or derivatives thereof; for...
7273709 Detection of sarcocystis neurona  
A gene encoding a 29 kilodalton protein found on the surface of merozoite stage S. neurona has been cloned and sequenced. The protein encoded by this gene, termed SnSAG-1, is an immunodominant...
7264939 Method of detecting native proBNP  
The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the...
7264805 Proteins with a high immunoreactivity and a method for the production thereof  
The invention relates to (glyco-) proteins, in particular monoclonal antibodies, which have an immunoreactivity of >81%, preferably >90%. The inventive monoclonal antibodies are produced using a...
7258989 Carbohydrate deficient transferrin (CDT) -specific antibodies, their preparation and use  
The present invention relates to antibodies which, in agueous solution, selectively bind to a transferrin-homologous carbohydrate deficient transferrin (CDT) without the latter needing to be bound...
7250494 Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria  
The present invention encompasses monoclonal antibodies that bind to lipoteichoic acid (LTA) of Gram positive bacteria. The antibodies also bind to whole bacteria and enhance phagocytosis and...
7244580 Epsilon immunoglobulin chain derived peptides for induction of anti-IgE antibodies  
The present invention relates to identification of polypeptides useful for generating antibodies specific for non-human IgE, particularly equine IgE. The invention, therefore, also relates to...
7241578 Immunoassay method/equipment, biological component measurable toilet, anti-albumin monoclonal antibody, cell strain producing the same, and albumin detection kit  
The immunoassay method of this invention measures the content of a subject substance in a sample. The method includes the steps of: (a) preparing a mixed solution by mixing the sample and an...
7223549 Compositions for identification and isolation of stem cells  
The invention provides monoclonal antibodies that selectively bind to ectodermally- and endodermally-derived stem cells and methods for the diagnosis of a neoplasm in a subject by contacting a...
7220559 Development of human monoclonal antibodies and uses thereof  
This invention provides: a heteromyeloma, other than B6B11, capable of producing a trioma when fused with a human lymphoid cell, wherein the trioma is capable of producing a monoclonal...
7217528 Antibodies to HFXJW48 polypeptide  
The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells,...
RE39586 Human monoclonal antibody against Hepatitis B virus surface antigen (HBVSAG)  
Disclosed is a hybridoma cell line which produces human antibodies capable of binding to the hepatitis B virus surface antigen (HBVsAg), as well as antibodies produced by the cell line. Also...
7195926 Antibodies to a cathepsin C homolog  
The present invention provides nucleotide and amino acid sequences that identify and encode a new cathepsin C homolog (RCP) expressed in THP-1 cells. The present invention also provides for...
7196175 Antibodies to JTT-1 protein and cells secreting such antibodies  
Novel cell surface molecules recognized by monoclonal antibodies against a cell surface molecule of lymphocytic cells that play an important role in autoimmune diseases and allergic diseases have...
7189397 Cytotoxicity mediation of cells evidencing surface expression of CD44  
This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease...
7189824 Tumor vessel endothelial cell-binding monoclonal antibodies  
A monoclonal antibody which recognizes an antigen of a molecular weight of 40 kD or 80 kD on the surface of tumor vessel endothelial cells, hybridomas producing the monoclonal antibody,...
7189825 Cancerous disease modifying antibodies  
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
7157257 Method of treating biological cells and/or their cell components with electrical fields  
A method is described for treating biological cells and/or their cell components with electrical fields in a reaction medium, in which an inhibitor is added to the reaction medium to counteract...
7153701 Method for quantitatively detecting antigen  
A method for quantitatively detecting an antigen which comprises (1) a first step of providing an Fab′ antibody having a uniform isoelectric point, said antibody forming an immune complex with an...
7148332 High affinity monoclonal antibody for recognizing the estrogen receptor (ER) and method for creating the antibody  
High affinity monoclonal antibodies for recognizing estrogen receptor (clone SP1) with immunohistochemistry and methods for creating such an antibody are disclosed. The lagomorph derived ER...
7148040 Method of rapid production of hybridomas expressing monoclonal antibodies on the cell surface  
The present invention relates to genetically altered hybridomas, myelomas and B cells. The invention also relates to utilizing genetically altered hybridomas, myelomas and B cells in methods of...
7138228 Protein O-sulfonation  
Post-translational O-sulfonation of a serine or threonine residue of proteins is detected, optionally comparatively, wherein the detected O-sulfonation is detected under a first physiological...
7138241 Hybridoma, an antibody resistant to an interfering substance, and a kit for immunological analysis  
The present invention provides for a method of selecting an antibody against a target substance to be measured, which comprises selecting the antibody against the target substance by...
7135295 Detection of small molecules by use of a piezoelectric sensor  
A protein comprising an antigen-binding portion formed by two cooperating peptide sequences of FIGS. 3A and 3B of the application. The protein may alternatively comprise an altered antigen-binding...
7135555 Mammalian TNF-α convertases  
The present invention provides isolated human and bovine TNF-α convertases, nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and...
7132281 Methods and host cells for producing human monoclonal antibodies to CTLA-4  
In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucelotide sequences encoding and amino acid...
7132511 Modified anti-EGFR antibodies with reduced immunogenicity  
The present invention relates to antibodies which are directed to the EGF receptor (HER1) to be administered especially to humans and in particular for therapeutic use in tumors. The antibodies...
7118924 Method for producing human antibodies in SCID mice which uses dendritic cells pulsed with antigen-antibody complexes and antigen-antibody complexes as immunizing agents  
An improved method for producing human antibodies in SCID mice is provided. The improvement includes the use of dendritic cells pulsed with antigen-antibody complexes and antigen-antibody...
7118890 Antibodies to vertebrate delta proteins and fragments  
The present invention relates to nucleotide sequences of vertebrate Delta genes, and amino acid sequences of their encoded proteins, as well as derivatives (e.g., fragments) and analogs thereof....
7115715 Anti-idiotype antibodies to MN proteins and MN polypeptides  
Herein disclosed is a novel oncogene named MN or alternatively MN/CA IX. Abnormal expression of the MN gene is shown to signify oncogenesis, and diagnostic/prognostic methods for...
7109309 Peptide fructose and protein conjugate with the same  
It is intended to provide an antibody specific to HbA1c, antibody-producing cells capable of supplying the antibody in a stable state in the future, and a method of constructing the...
7109003 Methods for expressing and recovering human monoclonal antibodies to CTLA-4  
In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucelotide sequences encoding and amino acid...
7105643 Monoclonal antibodies specific for crack cocaine metabolites, a cell line producing the same, and crack cocaine conjugates  
A monoclonal antibody, and a cell line capable of producing the same, has been produced with the ability to detect the primary metabolites generated from the pyrolysis of smokeable, or “crack”,...