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7045692 |
Hybrid maize 33N29
A novel hybrid maize variety designated 33N29 and seed, plants and plant parts thereof, produced by crossing two Pioneer Hi-Bred International, Inc. proprietary inbred maize lines. Methods for...
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7041479 |
Enhanced in vitro synthesis of active proteins containing disulfide bonds
Compositions and methods are provided for the enhanced in vitro synthesis of polypeptides containing disulfide bonds. In order to improve the performance of in vitro protein synthesis reactions,...
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7041808 |
Antimicrobial proteins, genes encoding the proteins and method of using the same
It is intended to provide thermotolerant and antimicrobial proteins having a broad antibacterial spectrum and being useful in the agricultural, medical and industrial field; and plants resistant to...
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7041887 |
Hybrid maize 33D63
A novel hybrid maize variety designated 33D63 and seed, plants and plant parts thereof, produced by crossing two Pioneer Hi-Bred International, Inc. proprietary inbred maize lines. Methods for...
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7037662 |
Receptor-ligand system and assay
An Eph family RTK (receptor tyrosine kinase) ligand-binding domain as well as a method of identifying Eph family RTK agonists or antagonist. The ligand-binding domain is suitably encoded by exon...
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7037676 |
Drosophila tumor necrosis factor class molecule polynucleotides and variants thereof
The present invention provides novel polynucleotides encoding Drosophila DmTNF polypeptides, fragments and homologs thereof. The present invention also is directed to novel polynucleotides...
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7037677 |
Megakaryocytic protein tyrosine kinase I
The present invention relates to novel cytoplasmic tyrosine kinases isolated from megakaryoctyes (megakaryocyte kinases or MKKs) which are involved in cellular signal transduction pathways and to...
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7034002 |
Angiotensin converting enzyme inhibitor
The present invention provides an angiotensin converting enzyme inhibitor having strong activity of inhibiting angiotensin converting enzyme, good hue and easily to take in which is a composition...
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7034214 |
Hybrid maize 35Y33
A novel hybrid maize variety designated 35Y33 and seed, plants and plant parts thereof, produced by crossing two Pioneer Hi-Bred International, Inc. proprietary inbred maize lines. Methods for...
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7030303 |
Hybrid maize 38B85
According to the invention, there is provided a hybrid maize plant, designated as 38B85, produced by crossing two Pioneer Hi-Bred International, Inc. proprietary inbred maize lines. This invention...
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7030295 |
Modified Cry3A toxins and nucleic acid sequences coding therefor
Compositions and methods for controlling plant pests are disclosed. In particular, novel nucleic acid sequences encoding modified Cry3A toxins having increased toxicity to corn rootworm are...
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7022329 |
Method for treating neurogenic inflammation pain with botulinum toxin and substance P components
The present invention relates to methods for treating neurogenic inflammation pain. The methods include administering an effective amount of a composition which includes a botulinum toxin...
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7022903 |
Inbred corn line W69079
An inbred corn line, designated W69079, is disclosed. The invention relates to the seeds of inbred corn line W69079, to the plants of inbred corn line W69079 and to methods for producing a corn...
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7018809 |
Expression of functional antibody fragments
Methods for the high yield production of antibody Fv-containing polypeptides, especially Fab′ and F(ab′) 2 antibody fragments are provided. Expression of heavy and light chain Fv in a...
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7008779 |
PHELIX: a testis-specific protein expressed in cancer
Described is a novel gene and its encoded basic Helix Loop Helix protein, termed PHELIX, and to diagnostic and therapeutic methods and compositions useful in the management of various cancers which...
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7009043 |
Plus end-directed microtubule motor required for chromosome congression
The invention provides isolated nucleic acid and amino acid sequences of Xenopus CENP-E (XCENP-E), antibodies to XCENP-E, methods of screening for CENP-E modulators using biologically active...
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7002064 |
Inbred corn line A60059
An inbred corn line, designated A60059, is disclosed. The invention relates to the seeds of inbred corn line A60059, to the plants of inbred corn line A60059 and to methods for producing a corn...
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6996472 |
Drift compensation method for fingerprint spectra
Methods of compensating for drift in fingerprint spectra of microorganisms caused by changes in their environment are disclosed. These methods of compensating for drift permit identification of...
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6989477 |
Inbred corn line 5020
An inbred corn line, designated 5020, is disclosed. The invention relates to the seeds of inbred corn line 5020, to the plants of inbred corn line 5020 and to methods for producing a corn plant,...
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6984382 |
Bifunctional protein, preparation and use
A bifunctional protein comprising: 1) a single-chain antibody directed against a suitable antigen on a tumour cell, 2) a hinge region comprising from about 40 to about 200 amino acids joined to the...
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6984488 |
Determination and control of bimolecular interactions
Methods of using overlapping peptides for the discovery of discontinuous epitopes, as vaccines, for drug design, for diagnostic purposes and for the elucidation of three-dimensional protein...
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6984779 |
Inbred corn line G1103
Broadly this invention provides an invention which is inbred corn line G1103. The methods for producing a corn plant by crossing the inbred line G1103 are also encompassed by the invention....
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6982371 |
Hybrid maize plant and seed 31Y43
According to the invention, there is provided a hybrid maize plant, designated as 31Y43, produced by crossing two Pioneer Hi-Bred International, Inc. proprietary inbred maize lines. This invention...
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6979763 |
Hybrid maize plant & seed 38G60
According to the invention, there is provided a hybrid maize plant, designated as 38G60, produced by crossing two Pioneer Hi-Bred International, Inc. proprietary inbred maize lines. This invention...
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6977150 |
Process and compositions for peptide, protein and peptidomimetic synthesis
The present invention is a simplified, highly-purified, processive translation system that does not require the addition of translation factors EF-P, W, W2 or rescue. A new translation process...
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6972350 |
Pest-resistant plants comprising a construct encoding a vacuole targeting sequence and avidin or streptavidin
This invention relates to nucleic acids encoding chimeric polypeptides comprising vacuole targeting sequences and sequences encoding avidin or streptavidin. The nucleic acids are useful for...
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6965063 |
Hybrid maize plant and seed 30A29
According to the invention, there is provided a hybrid maize plant, designated as 30A29, produced by crossing two Pioneer Hi-Bred International, Inc. proprietary inbred maize lines. This invention...
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6962814 |
Decellularized tissue engineered constructs and tissues
New methods for producing tissue engineered constructs and engineered native tissues are disclosed. The methods include producing a tissue engineered construct by growing cells in vitro on a...
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6962797 |
Nucleic acids encoding PRO615
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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6962812 |
Culture medium for culture of animal cell and method for producing protein using same
A culture medium for culture of an animal cell, characterized by containing an enzymatic degradation product of fish meat or a fish meat extract, and a method for producing a desired protein with...
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6962695 |
Modification of interferon alpha production
A process for the production of α-interferon comprising the steps: i) inducing of human leukocytes by means of a virus; ii) treating the leukocytes with an enhancing agent selected from: a)...
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6953844 |
Isolation of neurotrophins from a mixture containing neurotrophin variants using hydrophobic interaction chromatography
Methods are provided for large scale purification of neurotrophins, including mature NGF, suitable for clinical use. The methods provide means to separate neurotrophins from various less desirable...
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6951928 |
Nucleic acid molecule encoding a (poly)peptide co-segregating in mutated form with Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)
APECED (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) is the only described systemic autoimmune disease with monogenic background. We have isolated a novel polynucleotide in...
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6951756 |
Closure of bacterial ghost
The invention relates to a method for preparing closed bacterial ghosts by means of vesicle membrane fusion and to the bacterial ghosts which can be obtained in this way. Active compounds, e.g....
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6946292 |
Cells producing antibody compositions with increased antibody dependent cytotoxic activity
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a...
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6936437 |
Methods and compositions for production of recombinant peptides
This invention provides a method for solubilizing and recovering in bioactive form, a target polypeptide or protein that has been expressed from a host organism in insoluble form. The polypeptide...
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6933135 |
Antibodies specific for intracellular domain of protein tyrosine phosphatase
Antibodies to intracellular domains of two or more kinds of protein tyrosine phosphatases, methods for generation thereof and cells producing these antibodies are disclosed. The antibody of the...
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6929917 |
Method for cloning of a rare, specifically mutated cell
The invention concerns a new method of detecting a rare product of a directed genetic alteration of a cultured cell. The method is applicable to any method of making the alteration provided that a...
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6927043 |
Interleukin-2 mutein expressed from mammalian cells
Glycosylated interleukin-2 muteins are described. A method of producing the muteins using mammalian cells is included. The muteins may be incorporated into pharmaceutical preparations useful for,...
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6927279 |
Antithrombin nucleotides and proteins from horn fly
Compositions and methods for preventing hematophagous infestation of cattle are provided, directed at isolated proteins with antithrombin activity and nucleotide sequences encoding the proteins....
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6924356 |
Human protein HHEPU32
The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells,...
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6924124 |
Feeding strategies for cell culture
The invention is in the field of cell culture, particularly recombinant cell culture. More specifically, the invention relates to methods of fed batch CHO cell culture.
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6921665 |
Selective antibody targeting of undifferentiated stem cells
This invention provides a system for producing differentiated cells from a stem cell population for use wherever a relatively homogenous cell population is desirable. The cells contain an effector...
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6921634 |
Replication competent hepatitus C virus and methods of use
The present invention provides a replication competent hepatitis C virus that includes a heterologous polynucleotide. The invention also includes methods for modifying a hepatitis C virus...
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6919186 |
Fluorescent proteins
The present invention provides novel engineered derivatives of green fluorescent protein (GFP) which have an amino acid sequence which is modified by amino acid substitution compared with the amino...
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6911324 |
Induction of beta cell differentiation in human cells
The present invention provides methods for inducing insulin gene expression in cultured pancreas cells, the method comprising contacting a culture of endocrine pancreas cells expressing a PDX-1...
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6908619 |
Camp factor of streptococcus uberis
The CAMP factor gene of Streptococcus uberis ( S. uberis ) is described, as well as the recombinant production of CAMP factor therefrom. CAMP factors can be used in vaccine compositions for the...
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6903202 |
DNA encoding proteins that inhibit Hsp70 function
Human heat-shock protein-binding proteins (HspBP-1 and HspBP-2) are disclosed with the polynucleotides which identify and encode them. Genetically engineered expression vectors and host cells...
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6900010 |
Compositions and methods for detecting human immunodeficiency virus
Methods are provided for screening natural and synthetic anti-HIV agents using recombinant cells that are rendered susceptible to productive infection of various strains, subtypes or clades of HIV...
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6900036 |
Prion isomers, methods of making, methods of using, and compositions and products comprising prion isomers
Prion peptides exhibiting structural isomerism to wild-type prion peptide are disclosed. The invention further discloses methods of making prion isomers, compositions comprising prion isomers, and...
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