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5968815 |
Promoter of M. paratuberculosis and its use for the expression of immunogenic sequences
The invention relates to a nucleotide sequence which is present at a position adjacent to the 5' end of the reverse sequence complementary to the open reading frame coding for a potential...
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5968775 |
Hepatitis C virus infected cell systems
The present invention is directed to extracorporeal cell systems infected with hepatitis C virus (HCV). The present invention also relates to products of such cell systems and their use as vaccines...
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5965404 |
Method for introducing nucleic acids into higher eukaryotic cells
Process and medium for the transfection of higher eukaryotic cells with DNA/polycation complexes, wherein a medium is used which contains ethyleneglycol and/or glycerol. The medium may also contain...
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5965132 |
Methods and compositions for targeting the vasculature of solid tumors
The present invention relates generally to methods and compositions for targeting the vasculature of solid tumors using immunological- and growth factor-based reagents. In particular aspects,...
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5965792 |
Nucleic acids encoding metal uptake transporters and their uses
The invention provides LCT1 nucleic acids which encode metal ion uptake transporters. The invention also provides methods of modulating heavy metal and alkali metal uptake in plants. The methods...
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5962224 |
Isolated DNA encoding p62 polypeptides and uses therefor
Isolated nucleic acid molecules encoding novel members of the p62 family of polypeptides which include, in preferred embodiment, an SH2 binding domain and a ubiquitin binding domain are described....
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5958676 |
Genetically engineered cell lines for detecting infectious herpesvirus and methods therefor
A diagnostic assay for detecting the presence of an infectious herpesvirus in a specimen and a genetically engineered cell line for use in such assay are disclosed. The cell line used in the assay...
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5958733 |
Threonyl tRNA synthetase polynucleotides
The invention provides thrS polypeptides and DNA (RNA) encoding thrS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing thrS...
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5958734 |
Polynucleotides encoding gluS polypeptides of streptococcus pneumoniae
The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS...
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5955313 |
Nucleic acid molecule encoding a bifunctional protein, the protein so encoded uses thereof
The invention involves the identification of an isolated nucleic acid molecule which encodes a tumor rejection antigen. Various uses of this nucleic acid molecule and the protein it encodes are...
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5945287 |
Nucleic acids encoding two human heat shock protein homologs, and methods of detection thereof
The invention provides two human heat shock protein homologs (HSPHH-1, HSPHH-2) and polynucleotides which identify and encode HSPHH-1 and HSPHH-2. The invention also provides expression vectors,...
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5942417 |
CD44-like protein and nucleic acids
The present invention concerns a novel CD44-like protein receptor. In particular, isolated nucleic acid molecules are provided encoding the CD44-like protein. CD44-like polypeptides are also...
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5942662 |
Inducible herbicide resistance
The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing...
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5939318 |
Cholesterol disposal fusion enzymes
Fusion enzymes having multiple segments of different biological activity including one segment having P450scc activity and at least one segment having electron-transfer activity for transferring...
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5939288 |
Plant secretory signal peptides and nectarins
Provided herein are signal peptides, and constructs and vectors having signal peptides, as well as methods of using signal peptides to deliver proteins into secretory material. The invention...
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5935820 |
Polynucleotides encoding vascular endothelial growth factor 2
The present invention relates to polynucleotides encoding a novel human protein called Vascular Endothelial Growth Factor 2, or VEGF-2, as well as mature forms, proproteins, and fragments of...
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5932438 |
Preparation of thaumatin sweeteners
Thaumatins, protein sweeteners, are obtained through the expression of artificial, synthetic and substantially optimized genes, preferably in filamentous fungi such as Penicillium roquefortii,...
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5932449 |
Detection of botulinum toxin
Recombinant antibody fragments (rFabs) specific to botulinum types A and B oxin complexes are provided. These rFabs are useful as immunosensors for detecting botulinum toxin in food, health care,...
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5928914 |
Methods and compositions for transforming cells
Methods and compositions for transforming cells, resulting in efficient and stable site-specific integration of transgenes, are disclosed. Transformation is achieved by introducing into a cell an...
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5928882 |
Treatment and prevention of neurodegenerative diseases using modulators of Fe65
Modulators of the protein Fe65 can be utilized to affect the interaction of the protein Fe65 with the cytoplasmic domain of amyloid precursor protein and thus provide therapeutics for the treatment...
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5928868 |
Three hybrid screening assay
Methods and a kit are provided for characterizing small molecules from a library of small molecules or alternatively identifying protein targets to which known small molecules bind. The methods...
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5928895 |
IgA Fc binding protein
The invention provides IgA Fc binding protein polypeptides and DNA (RNA) encoding IgA Fc binding protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also...
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5925807 |
GA4 DNA, protein and method of use
The invention relates to the DNA and protein encoded by the GA4 locus. This protein is believed to be a member of the family of enzymes involved in the biosynthesis of the gibberellin family (GA)...
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5919636 |
Attachment enhanced 293 cells
Attachment enhanced human embryonic kidney cells, 293, are provided. These cells have been modified to contain a selected mammalian scavenger gene, which has been found to improve the ability of...
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5917122 |
Tetracycline repressor-mediated binary regulation system for control of gene expression in transgenic mice
The present invention relates to a tetracycline repressor-mediated binary regulation system for the control of gene expression in transgenic mice. It is based, at least in part, on the discovery...
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5912411 |
Mice transgenic for a tetracycline-inducible transcriptional activator
Transgenic mice carrying a transgene comprising a nucleic acid molecule encoding protein useful for regulating the expression of genes in eukaryotic cells in a highly controlled manner are...
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5891670 |
Tetracycline resistance protein
The invention provides tetracycline resistance protein polypeptides and DNA (RNA) encoding tetracycline resistance protein polypeptides and methods for producing such polypeptides by recombinant...
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5891665 |
Untranslated leader sequences from RNA viruses as enhancers of translation
It has been shown that a 5' untranslated leader sequences of RNA virus non-structural genes act as enhancers of translation of mRNA. These leader sequences can be ligated upstream of an appropriate...
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5889190 |
Recombinant plant viral nucleic acids
The present invention is directed to recombinant plant viral nucleic acids and to hosts infected thereby. The recombinant plant viral nucleic acids comprise a native plant viral subgenomic...
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5885780 |
Method of obtaining small conformationally rigid conopeptides
A method for separating, identifying and purifying small, conotoxin-like rigidly conformed peptides ("conopeptides") containing multiple Cys residues comprises forming a conoeffector library, each...
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5885804 |
PhoH
The invention provides phoh polypeptides and DNA (RNA) encoding phoh polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing phoH...
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5882885 |
Glycogen phosphorylase
The invention provides glycogen phosphorylase polypeptides and DNA (RNA) encoding glycogen phosphorylase polypeptides and methods for producing such polypeptides by recombinant techniques. Also...
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5882891 |
Ferrichrome transport ATP-binding protein
The invention provides Ferrichrome transport ATP-Binding Protein polypeptides and DNA (RNA) encoding Ferrichrome transport ATP-Binding Protein polypeptides and methods for producing such...
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5882871 |
Saliva binding protein
The invention provides Saliva Binding Protein polypeptides and DNA (RNA) encoding Saliva Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also...
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5876962 |
Expression vectors for the synthesis of proteins and plasmid replicons and sequence cassettes for use in constructing such vectors
Expression vectors for the expression of proteins, particularly eukaryotic proteins are provided which are based on novel plasmid replicons. Sequence cassettes useful in constructing such vectors...
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5871742 |
Recombinant Avipox virus encoding polypeptide of mycoplasma gallisepticum, and utilized a live vaccine
A polypeptide exhibiting the antigenicity of Mycoplasma gallisepticum, a fused polypeptide comprising the above polypeptide and, connected to the N-terminus thereof, a signal membrane anchor of a...
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5869340 |
Plant clones containing elevated secondary metabolite levels
A method for selecting plants and plant tissue cultures that contain elevated levels of secondary metabolites is disclosed. The method uses clonal organogenic tissue culture lines, the cultures...
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5869636 |
Immunoreactive peptide sequence from a 43 kD human cancer antigen
A recombinant cell line expressing a polypeptide with the amino acid sequence -Gln-Asp-Leu-Thr-Met-Lys-Tyr-Gln-Ile- has been isolated. The cell line was described as a recombinant E. coli strain....
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5869256 |
Human coatomer vesicle protein
The present invention provides a human coatomer vesicle protein (HECOP) and polynucleotides which identify and encode HECOP. The invention also provides genetically engineered expression vectors...
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5866369 |
Amps
The invention provides ampS polypeptides and DNA (RNA) encoding ampS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ampS...
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5866365 |
RNC polynucleotides
The invention provides rnc polypeptides and DNA (RNA) encoding rnc polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing rnc...
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5866367 |
GIDB
The invention provides gidB polypeptides and DNA (RNA) encoding gidB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gidB...
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5866368 |
GreA
The invention provides greA polypeptides and DNA (RNA) encoding greA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing greA...
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5866370 |
Aminopeptidase
The invention provides aminopeptidase polypeptides and DNA (RNA) encoding aminopeptidase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are...
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5863770 |
Stable meterologous propagation of CFTR protein variant cDNA
A modified DNA sequence encoding full length cystic fibrosis transmembrane conductance regulator protein is provided to facilitate propagation and/or expression of the protein in living cells and...
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5861542 |
Gene controlling floral development and apical dominance in plants
The present invention provides compositions and methods for affecting the transition from vegetative to reproductive growth in a wide variety of plants. A MADS-box gene from rice, OsMADS1, has been...
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5861487 |
Genetic sequences encoding flavonoid pathway enzymes and uses therefor
The present invention relates to a nucleic acid isolate comprising a sequence of nucleotides encoding, or complementary to a sequence encoding, a dihydrokaempferol (DHK) hydroxylating enzyme or...
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5861281 |
Lacc
The invention provides lacC polypeptides and DNA (RNA) encoding lacC polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing lacC...
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5858720 |
Hiss
The invention provides hisS polypeptides and DNA (RNA) encoding hisS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing hisS...
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5859347 |
Enhanced expression in plants
This invention provides HSP70 introns that when present in a non-translated leader of a chimeric gene enhance expression in plants.
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